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Aprea Therapeutics, Inc. Financials

APRE
FY2025 annual
Revenue Not reported for FY2025
Net Income -$12.6M +2.8% YoY
EPS (Diluted) -$1.93 YoY not available
Free Cash Flow Not reported for FY2025
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

This page shows Aprea Therapeutics, Inc. (APRE) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 9 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI APRE FY2025

Equity-funded drug development is sustaining operations as cash burn eases, but the cash cushion keeps shrinking.

In FY2025, net loss of -$12.6M and operating cash burn of -$12.9M were nearly identical, so the reported loss is translating into real cash use rather than being distorted by large non-cash items. But cash still fell to $14.6M even with financing inflows, and the doubling of shares outstanding over the last two annual periods shows the company is funding that burn mainly through equity issuance instead of debt.

The balance sheet is still liquid: cash of $14.6M and a 5.6x current ratio suggest near-term obligations are manageable. With total liabilities of just $3.5M and no reported long-term debt, the operating constraint is maintaining research funding, not meeting lender claims.

The recent improvement in losses looks more like a research-spend reset than broad operating leverage. R&D fell to $7.0M in FY2025 from $9.4M in FY2024 while SG&A was essentially flat, so lower burn appears to come from dialing back development activity rather than from a structurally leaner corporate base.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

Aprea Therapeutics, Inc. does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Piotroski F-Score Partial
0/6

Aprea Therapeutics, Inc. passes 0 of 6 computable financial strength tests (3 of the nine could not be computed from available data). No profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution).

Earnings Quality No Cash Backing
N/A

Aprea Therapeutics, Inc. reported a net loss of $12.6M while operations used $12.9M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

EBITDA
-$13.2M
YoY+7.6%

Aprea Therapeutics, Inc.'s EBITDA was -$13.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 7.6% from the prior year.

Net Income
-$12.6M
YoY+2.8%

Aprea Therapeutics, Inc. reported -$12.6M in net income in fiscal year 2025. This represents an increase of 2.8% from the prior year.

EPS (Diluted)
-$1.93

Aprea Therapeutics, Inc. earned -$1.93 per diluted share (EPS) in fiscal year 2025.

Revenue

Not reported for fiscal year 2025.

Cash & Balance Sheet

Cash & Debt
$14.6M
YoY-36.1%
5Y CAGR-30.3%

Aprea Therapeutics, Inc. held $14.6M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
11M

Aprea Therapeutics, Inc. had 11M shares outstanding in fiscal year 2025.

Free Cash Flow

Not reported for fiscal year 2025.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Return on Equity
-101.3%
YoY-34.1pp
5Y CAGR-32.2pp

Aprea Therapeutics, Inc.'s ROE was -101.3% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 34.1 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not reported for fiscal year 2025.

Net Margin

Not reported for fiscal year 2025.

Capital Allocation

R&D Spending
$7.0M
YoY-24.8%
5Y CAGR-28.6%

Aprea Therapeutics, Inc. invested $7.0M in research and development in fiscal year 2025. This represents a decrease of 24.8% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

Capital Expenditures

Not reported for fiscal year 2025.

APRE Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

APRE annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17
R&D ExpensesN/A$7.0M-24.8%$9.4M+22.8%$7.6M-53.5%$16.4M-31.4%$23.9M-36.9%$37.9M+80.8%$21.0M+47.6%$14.2M+6.0%$13.4M
SG&A ExpensesN/A$6.5M+0.3%$6.5M-23.4%$8.4M-59.8%$21.0M+54.8%$13.6M-9.3%$14.9M+73.8%$8.6M+274.5%$2.3M-6.7%$2.5M
Operating IncomeN/A-$13.2M+7.6%-$14.3M+7.4%-$15.5M+86.4%-$113.4M-202.8%-$37.4MN/AN/AN/AN/A
Income TaxN/A$0$0$0$0$0$0$0$0$0
Net IncomeN/A-$12.6M+2.8%-$13.0M+9.3%-$14.3M+87.3%-$112.7M-203.4%-$37.1M+30.6%-$53.5M-90.6%-$28.1M-80.7%-$15.5M-2.2%-$15.2M
EPS (Diluted)-$1.93-$2.35-$3.95-$67.99-$34.88+31.1%-$50.61-$4.67N/AN/A

Not reported in any period shown, so not listed: Revenue, Cost of Revenue, Gross Profit, Interest Expense.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

APRE Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

APRE annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17
Total Assets$15.9M-33.6%$24.0M+5.9%$22.7M-24.9%$30.2M-46.9%$56.8M-38.8%$92.8M-30.5%$133.6M+102.4%$66.0MN/A
Current Assets$15.6M-34.0%$23.6M+4.7%$22.5M-25.3%$30.2M-46.7%$56.6M-38.8%$92.4M-30.5%$133.0M+101.6%$66.0MN/A
Cash & Equivalents$14.6M-36.1%$22.8M+5.8%$21.6M-24.9%$28.8M-45.8%$53.1M-40.4%$89.0M-31.6%$130.1M+98.1%$65.7M+169.1%$24.4M
Total Liabilities$3.5M-25.3%$4.7M-18.0%$5.7M+78.0%$3.2M-56.2%$7.3M-52.5%$15.4M+64.6%$9.4M-92.0%$117.5MN/A
Current Liabilities$2.8M-17.8%$3.4M-23.4%$4.4M+37.0%$3.2M-56.2%$7.3M-52.3%$15.3M+69.2%$9.1M+86.1%$4.9MN/A
Total Equity$12.4M-35.6%$19.3M+13.9%$17.0M-33.9%$25.6M-48.2%$49.5M-36.0%$77.4M-37.7%$124.2M+341.5%-$51.4M-43.8%-$35.8M
Retained Earnings-$333.6M-3.9%-$321.0M-4.2%-$308.1M-4.9%-$293.8M-62.2%-$181.1M-25.8%-$144.0M-59.1%-$90.5M-44.9%-$62.5MN/A

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

APRE Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

APRE annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17
Operating Cash Flow-$12.2M-$12.9M+4.9%-$13.6M-11.3%-$12.2M+51.3%-$25.0M+33.6%-$37.7M+9.8%-$41.8M-56.5%-$26.7M-75.1%-$15.3M-8.9%-$14.0M
Capital ExpendituresN/AN/A$15K-83.4%$93KN/AN/A$26K-16.8%$31K+734.7%$4KN/A
Free Cash FlowN/AN/A-$13.6M-10.6%-$12.3MN/AN/A-$41.8M-56.4%-$26.7M-75.3%-$15.3MN/A
Investing Cash FlowN/AN/A-$15K+83.4%-$93KN/AN/A-$26K+16.8%-$31K-734.7%-$4KN/A
Financing Cash Flow$36.9M$4.6M-68.7%$14.8M+188.4%$5.1M+652.6%$683K-60.9%$1.7M+1057.4%$151K-99.8%$92.6M+64.2%$56.4M+141.5%$23.3M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

APRE Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

APRE annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17
Return on Equity-101.3%-34.1pp-67.1%+17.1pp-84.3%+355.1pp-439.3%-364.3pp-75.0%-5.9pp-69.1%-46.5pp-22.6%N/AN/A
Return on Assets-79.1%-25.0pp-54.0%+9.0pp-63.1%+310.5pp-373.6%-308.3pp-65.3%-7.7pp-57.6%-36.6pp-21.0%+2.5pp-23.5%N/A
Current Ratio5.63-1.4x7.01+1.9x5.14-4.3x9.42+1.7x7.73+1.7x6.03-8.7x14.68+1.1x13.56N/A
Debt-to-Equity0.280.0x0.24-0.1x0.34+0.2x0.120.0x0.15-0.1x0.20+0.1x0.08N/AN/A

Not reported in any period shown, so not listed: Gross Margin, Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

Is Aprea Therapeutics, Inc. profitable?

No, Aprea Therapeutics, Inc. (APRE) reported a net income of -$12.6M in fiscal year 2025.

What is Aprea Therapeutics, Inc.'s earnings per share (EPS)?

Aprea Therapeutics, Inc. (APRE) reported diluted earnings per share of -$1.93 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

What is Aprea Therapeutics, Inc.'s EBITDA?

Aprea Therapeutics, Inc. (APRE) had EBITDA of -$13.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Aprea Therapeutics, Inc. (APRE) has a return on equity of -101.3% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Aprea Therapeutics, Inc. (APRE) recorded an outflow of $12.9M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Aprea Therapeutics, Inc. (APRE) had $15.9M in total assets as of fiscal year 2025, including both current and long-term assets.

Aprea Therapeutics, Inc. (APRE) invested $7.0M in research and development during fiscal year 2025.

Aprea Therapeutics, Inc. (APRE) had 11M shares outstanding as of fiscal year 2025.

Aprea Therapeutics, Inc. (APRE) had a current ratio of 5.63 as of fiscal year 2025, which is generally considered healthy.

Aprea Therapeutics, Inc. (APRE) had a debt-to-equity ratio of 0.28 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Aprea Therapeutics, Inc. (APRE) had a return on assets of -79.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

At the end of fiscal year 2025, Aprea Therapeutics, Inc. (APRE) held $14.6M in cash, cash equivalents and investments, and reported an operating cash outflow of $12.9M over that year. Dividing the one by the other, the reported balance equals about 14 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Aprea Therapeutics, Inc. (APRE) has a Piotroski F-Score of 0 out of 6 computable signals; 3 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Aprea Therapeutics, Inc. (APRE) reported a net loss of $12.6M while operations used $12.9M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

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