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Centessa Pharmaceuticals Plc Financials

CNTA
Source SEC Filings (10-K/10-Q) Updated Mar 31, 2026 Currency USD FYE March

This page shows Centessa Pharmaceuticals Plc (CNTA) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 7 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 40 / 100
Financial Profile 40/100

Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
0

Centessa Pharmaceuticals Plc has an operating margin of -1384.6%, meaning the company retains $-1385 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses.

Leverage
98

Centessa Pharmaceuticals Plc carries a low D/E ratio of 0.21, meaning only $0.21 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 98/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
100

With a current ratio of 8.57, Centessa Pharmaceuticals Plc holds $8.57 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 100/100.

Cash Flow
0

While Centessa Pharmaceuticals Plc generated -$193.8M in operating cash flow, capex of $371K consumed most of it, leaving -$194.2M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Returns
0

Centessa Pharmaceuticals Plc generates a -37.5% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is up from -58.7% the prior year.

Piotroski F-Score Neutral
4/9

Centessa Pharmaceuticals Plc passes 4 of 9 financial strength tests. 2 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality Low Quality
0.98x

For every $1 of reported earnings, Centessa Pharmaceuticals Plc generates $0.98 in operating cash flow (-$193.8M OCF vs -$197.5M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Interest Coverage At Risk
-18.1x

Centessa Pharmaceuticals Plc earns $-18.1 in operating income for every $1 of interest expense (-$207.7M vs $11.5M). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$15.0M

Centessa Pharmaceuticals Plc generated $15.0M in revenue in fiscal year 2025.

EBITDA
-$206.8M
YoY-3.3%

Centessa Pharmaceuticals Plc's EBITDA was -$206.8M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 3.3% from the prior year.

Net Income
-$197.5M
YoY+16.2%

Centessa Pharmaceuticals Plc reported -$197.5M in net income in fiscal year 2025. This represents an increase of 16.2% from the prior year.

EPS (Diluted)
$-1.46
YoY+29.1%

Centessa Pharmaceuticals Plc earned $-1.46 per diluted share (EPS) in fiscal year 2025. This represents an increase of 29.1% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$194.2M
YoY-36.7%

Centessa Pharmaceuticals Plc generated -$194.2M in free cash flow in fiscal year 2025, representing cash available after capex. This represents a decrease of 36.7% from the prior year.

Cash & Debt
$61.3M
YoY-84.0%
5Y CAGR+53.4%

Centessa Pharmaceuticals Plc held $61.3M in cash against $110.1M in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
155M
YoY+16.5%

Centessa Pharmaceuticals Plc had 155M shares outstanding in fiscal year 2025. This represents an increase of 16.5% from the prior year.

Margins & Returns

Gross Margin
N/A
Operating Margin
-1384.6%

Centessa Pharmaceuticals Plc's operating margin was -1384.6% in fiscal year 2025, reflecting core business profitability.

Net Margin
-1316.9%

Centessa Pharmaceuticals Plc's net profit margin was -1316.9% in fiscal year 2025, showing the share of revenue converted to profit.

Return on Equity
-37.5%
YoY+21.2pp

Centessa Pharmaceuticals Plc's ROE was -37.5% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 21.2 percentage points from the prior year.

Capital Allocation

R&D Spending
$172.2M
YoY+14.6%
5Y CAGR+79.3%

Centessa Pharmaceuticals Plc invested $172.2M in research and development in fiscal year 2025. This represents an increase of 14.6% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$371K
YoY+991.2%

Centessa Pharmaceuticals Plc invested $371K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 991.2% from the prior year.

CNTA Income Statement

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24
Revenue $0 $0-100.0% $15.0M N/A $0 $0 $0 N/A
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses $41.6M-2.8% $42.7M+27.8% $33.4M N/A $33.9M+3.3% $32.8M+44.9% $22.7M N/A
SG&A Expenses $12.2M+2.6% $11.9M-3.4% $12.3M N/A $12.5M+12.0% $11.2M-16.9% $13.4M N/A
Operating Income -$53.8M+1.6% -$54.7M-77.6% -$30.8M N/A -$46.4M-5.5% -$44.0M-21.9% -$36.1M N/A
Interest Expense $2.9M+0.2% $2.9M+0.2% $2.9M N/A $2.6M+1.3% $2.5M-0.2% $2.5M N/A
Income Tax $166K-78.7% $778K-44.3% $1.4M N/A $608K-13.8% $705K+46.6% $481K N/A
Net Income -$54.9M-9.0% -$50.3M-92.6% -$26.1M N/A -$42.6M+2.9% -$43.8M-15.2% -$38.0M N/A
EPS (Diluted) $-0.41-7.9% $-0.38-90.0% $-0.20 N/A $-0.37+7.5% $-0.40-5.3% $-0.38 N/A

CNTA Balance Sheet

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24
Total Assets $448.3M-8.9% $492.1M-6.8% $527.8M-8.5% $576.8M-5.4% $609.7M+52.9% $398.8M+21.5% $328.2M-8.9% $360.2M
Current Assets $307.7M+2.4% $300.4M-13.6% $347.7M-35.2% $536.4M-5.6% $568.4M+59.9% $355.5M+25.0% $284.5M-9.7% $315.1M
Cash & Equivalents $50.8M+14.8% $44.2M-57.9% $105.2M-72.6% $383.2M-3.0% $395.0M+210.1% $127.4M+7.7% $118.2M-7.7% $128.0M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A N/A
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $146.7M-0.3% $147.2M+4.0% $141.6M-19.2% $175.3M+58.5% $110.6M-1.2% $111.9M-1.0% $113.0M-8.9% $124.0M
Current Liabilities $29.1M-1.9% $29.7M+22.7% $24.2M-58.3% $58.0M+119.6% $26.4M-1.3% $26.8M-2.5% $27.4M-30.3% $39.4M
Long-Term Debt $109.8M+0.2% $109.5M+0.3% $109.3M+0.3% $108.9M+43.9% $75.7M-1.0% $76.5M-0.4% $76.8M+1.5% $75.7M
Total Equity $301.6M-12.6% $344.9M-10.7% $386.2M-3.8% $401.5M-19.6% $499.1M+73.9% $287.0M+33.4% $215.2M-8.9% $236.2M
Retained Earnings -$1.1B-5.2% -$1.1B-5.0% -$1.0B-2.6% -$988.7M-12.7% -$877.4M-5.1% -$834.8M-5.5% -$791.0M-5.1% -$752.9M

CNTA Cash Flow Statement

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24
Operating Cash Flow -$58.3M-159.7% -$22.5M+60.8% -$57.2M-33.8% -$42.8M-100.1% -$21.4M+47.3% -$40.6M-8.8% -$37.3M-20.1% -$31.1M
Capital Expenditures $234K N/A N/A $0-100.0% $34K $0 $0-100.0% $28K
Free Cash Flow -$58.5M N/A N/A -$42.8M-99.8% -$21.4M+47.2% -$40.6M-8.8% -$37.3M-20.0% -$31.1M
Investing Cash Flow $61.9M+255.0% -$40.0M+82.0% -$222.4M-989.6% $25.0M-44.4% $45.0M+181.1% -$55.5M-430.9% $16.8M+191.7% -$18.3M
Financing Cash Flow $3.4M+114.1% $1.6M-48.0% $3.1M+4.2% $3.0M-98.8% $246.0M+133.6% $105.3M+903.7% $10.5M+65.0% $6.4M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

CNTA Financial Ratios

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin N/A N/A -205.2% N/A N/A N/A N/A N/A
Net Margin N/A N/A -174.2% N/A N/A N/A N/A N/A
Return on Equity -18.2%-3.6pp -14.6%-7.8pp -6.8% N/A -8.5%+6.7pp -15.3%+2.4pp -17.7% N/A
Return on Assets -12.2%-2.0pp -10.2%-5.3pp -5.0% N/A -7.0%+4.0pp -11.0%+0.6pp -11.6% N/A
Current Ratio 10.56+0.4 10.12-4.3 14.37+5.1 9.25-12.3 21.52+8.2 13.29+2.9 10.37+2.4 8.00
Debt-to-Equity 0.36+0.0 0.32+0.0 0.28+0.0 0.27+0.1 0.15-0.1 0.27-0.1 0.36+0.0 0.32
FCF Margin N/A N/A N/A N/A N/A N/A N/A N/A

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Frequently Asked Questions

Centessa Pharmaceuticals Plc (CNTA) reported $15.0M in total revenue for fiscal year 2025. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

No, Centessa Pharmaceuticals Plc (CNTA) reported a net income of -$197.5M in fiscal year 2025, with a net profit margin of -1316.9%.

Centessa Pharmaceuticals Plc (CNTA) reported diluted earnings per share of $-1.46 for fiscal year 2025. This represents a 29.1% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Centessa Pharmaceuticals Plc (CNTA) had EBITDA of -$206.8M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Centessa Pharmaceuticals Plc (CNTA) had $61.3M in cash and equivalents against $110.1M in long-term debt.

Centessa Pharmaceuticals Plc (CNTA) had an operating margin of -1384.6% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Centessa Pharmaceuticals Plc (CNTA) had a net profit margin of -1316.9% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Centessa Pharmaceuticals Plc (CNTA) has a return on equity of -37.5% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Centessa Pharmaceuticals Plc (CNTA) generated -$194.2M in free cash flow during fiscal year 2025. This represents a -36.7% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Centessa Pharmaceuticals Plc (CNTA) generated -$193.8M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Centessa Pharmaceuticals Plc (CNTA) had $687.5M in total assets as of fiscal year 2025, including both current and long-term assets.

Centessa Pharmaceuticals Plc (CNTA) invested $371K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Centessa Pharmaceuticals Plc (CNTA) invested $172.2M in research and development during fiscal year 2025.

Centessa Pharmaceuticals Plc (CNTA) had 155M shares outstanding as of fiscal year 2025.

Centessa Pharmaceuticals Plc (CNTA) had a current ratio of 8.57 as of fiscal year 2025, which is generally considered healthy.

Centessa Pharmaceuticals Plc (CNTA) had a debt-to-equity ratio of 0.21 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Centessa Pharmaceuticals Plc (CNTA) had a return on assets of -28.7% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Centessa Pharmaceuticals Plc (CNTA) had $61.3M in cash against an annual operating cash burn of $193.8M. This gives an estimated cash runway of approximately 4 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Centessa Pharmaceuticals Plc (CNTA) has a Piotroski F-Score of 4 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Centessa Pharmaceuticals Plc (CNTA) has an earnings quality ratio of 0.98x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Centessa Pharmaceuticals Plc (CNTA) has an interest coverage ratio of -18.1x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Centessa Pharmaceuticals Plc (CNTA) scores 40 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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