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Iteos Therapeutics, Inc. Financials

ITOS
FY2024 annual
Revenue $35.0M +177.9% YoY
Net Income -$134.4M -19.3% YoY
EPS (Diluted) -$3.32 -5.4% YoY
Free Cash Flow -$99.8M +6.5% YoY
Source SEC Filings (10-K/10-Q) Latest period Q2 FY2025, ended Jun 30, 2025 Reported Currency USD FYE December

Iteos Therapeutics, Inc. (ITOS) reported $35.0M in revenue for fiscal year 2024, up 177.9% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ITOS FY2024

A cash-funded development model is absorbing heavy R&D while revenue remains episodic and losses stay structurally large.

Revenue contracted between FY2021 and FY2022 while operating cash flow turned from positive to negative. That reversal, alongside positive earnings in FY2022, indicates the earlier profit burst did not establish a repeatable cash-generating operating base.

In FY2024, R&D consumed $145M against $35M of revenue, so development spending is occurring at a scale far above current commercial inflow. Operating cash flow was -$98.2M versus a net loss of -$134.4M; the gap means accounting loss exceeded cash outflow, an earnings-quality difference that likely reflects noncash items or working-capital timing.

Liabilities were 14.1% of assets, while debt-to-equity was 0.2x, indicating the asset base is not primarily debt-financed. The 12.6x current ratio and 80.1 months of reported outflow comparison describe substantial reported liquidity relative to near-term obligations and the latest annual operating deficit.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Profitability Growth Leverage Liquidity CashFlow Returns 34 / 100
Financial Health Score 34/100

Scored against operating companies for FY2024. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Iteos Therapeutics, Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Profitability
11

Iteos Therapeutics, Inc.'s reported operating margin for fiscal year 2024 is below the lowest share of revenue this page publishes, so the figure is not shown here. This dimension scores 11/100.

Growth
1

Iteos Therapeutics, Inc.'s revenue surged 177.9% year-over-year to $35.0M, reflecting rapid business expansion. This strong growth earns a score of 1/100.

Leverage
77

Iteos Therapeutics, Inc. carries a low D/E ratio of 0.16, meaning only $0.16 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 77/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
98

With a current ratio of 12.62, Iteos Therapeutics, Inc. holds $12.62 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 98/100.

Cash Flow
3

Iteos Therapeutics, Inc.'s reported free cash flow margin for fiscal year 2024 is below the lowest share of revenue this page publishes, so the figure is not shown here. This dimension scores 3/100.

Returns
13

Iteos Therapeutics, Inc. posts a -22.8% return on equity (ROE), meaning it loses $23 for every $100 of shareholders' equity. This results in a returns score of 13/100. This is down from -19.6% the prior year.

Altman Z-Score Grey Zone
2.87

Iteos Therapeutics, Inc. scores 2.87, placing it in the grey zone between 1.81 and 2.99. The score is driven primarily by a large market capitalization ($448.7M) relative to total liabilities ($96.7M). This signals moderate financial risk that warrants monitoring.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
2/7

Iteos Therapeutics, Inc. passes 2 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Iteos Therapeutics, Inc. reported a net loss of $134.4M while operations used $98.2M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$35.0M
YoY+177.9%

Iteos Therapeutics, Inc. generated $35.0M in revenue in fiscal year 2024. This represents an increase of 177.9% from the prior year.

EBITDA
-$158.3M
YoY-5.4%

Iteos Therapeutics, Inc.'s EBITDA was -$158.3M in fiscal year 2024, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 5.4% from the prior year.

Net Income
-$134.4M
YoY-19.3%

Iteos Therapeutics, Inc. reported -$134.4M in net income in fiscal year 2024. This represents a decrease of 19.3% from the prior year.

EPS (Diluted)
-$3.32
YoY-5.4%

Iteos Therapeutics, Inc. earned -$3.32 per diluted share (EPS) in fiscal year 2024. This represents a decrease of 5.4% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$99.8M
YoY+6.5%

Iteos Therapeutics, Inc. recorded an outflow of $99.8M in free cash flow in fiscal year 2024, representing a cash shortfall after capex. This represents an increase of 6.5% from the prior year.

Cash & Debt
$142.1M
YoY-43.4%
5Y CAGR+48.2%

Iteos Therapeutics, Inc. held $142.1M in cash as of fiscal year 2024; long-term debt is not reported for that period.

Shares Outstanding
38M
YoY+6.6%

Iteos Therapeutics, Inc. had 38M shares outstanding in fiscal year 2024. This represents an increase of 6.6% from the prior year.

Dividends Per Share

Not reported for fiscal year 2024.

Margins & Returns

Return on Equity
-22.8%
YoY-3.2pp

Iteos Therapeutics, Inc.'s ROE was -22.8% in fiscal year 2024, measuring profit generated per dollar of shareholder equity. This is down 3.2 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2024.

Operating Margin

Not shown for fiscal year 2024: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2024: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$145.4M
YoY+28.4%
5Y CAGR+49.9%

Iteos Therapeutics, Inc. invested $145.4M in research and development in fiscal year 2024. This represents an increase of 28.4% from the prior year.

Capital Expenditures
$1.6M
YoY-44.9%
5Y CAGR+17.8%

Iteos Therapeutics, Inc. invested $1.6M in capex in fiscal year 2024, funding long-term assets and infrastructure. This represents a decrease of 44.9% from the prior year.

Share Buybacks

Not reported for fiscal year 2024.

ITOS Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ITOS quarterly income statement
MetricQ2'25Q1'25Q4'24Q3'24Q2'24Q1'24Q4'23Q3'23
Revenue$0N/AN/A$0-100.0%$35.0M$0N/A$0
R&D Expenses$57.3M+97.2%$29.0MN/A$36.7M-0.1%$36.7M+6.3%$34.5MN/A$30.6M
SG&A Expenses$10.2M-7.3%$11.0MN/A$12.1M-2.8%$12.5M-1.9%$12.7MN/A$12.6M
Operating Income-$83.8M-109.4%-$40.0MN/A-$48.8M-244.5%-$14.2M+70.0%-$47.2MN/A-$43.3M
Income Tax$1.7M+51.8%$1.1MN/A$2.2M-0.8%$2.3M+2.1%$2.2MN/A-$1.2M
Net Income-$78.7M-127.5%-$34.6MN/A-$45.4M-536.3%-$7.1M+81.3%-$38.2MN/A-$32.2M
EPS (Diluted)-$1.81-126.3%-$0.80+22.3%-$1.03+1.9%-$1.05-483.3%-$0.18+83.2%-$1.07-25.9%-$0.85+5.6%-$0.90

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Interest Expense.

ITOS Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ITOS quarterly balance sheet
MetricQ2'25Q1'25Q4'24Q3'24Q2'24Q1'24Q4'23Q3'23
Total Assets$623.1M-5.4%$658.9M-4.1%$687.0M-5.0%$723.1M-3.8%$751.8M+19.4%$629.8M-5.7%$667.6M-1.5%$677.6M
Current Assets$529.0M-1.5%$537.0M+5.4%$509.5M-6.5%$544.9M-13.0%$626.6M+30.4%$480.4M-12.8%$550.7M-11.1%$619.1M
Cash & Equivalents$207.8M+32.8%$156.5M+10.1%$142.1M+14.9%$123.7M-50.7%$251.1M+71.2%$146.6M-41.6%$251.2M+23.0%$204.1M
Total Liabilities$129.3M+35.4%$95.4M-1.3%$96.7M+5.8%$91.4M+3.9%$88.0M-0.7%$88.6M-4.1%$92.4M+16.3%$79.4M
Current Liabilities$70.3M+84.9%$38.0M-5.8%$40.4M+9.6%$36.8M+6.2%$34.7M-2.5%$35.6M-11.1%$40.0M+41.8%$28.2M
Total Equity$493.8M-12.4%$563.4M-4.6%$590.3M-6.6%$631.7M-4.8%$663.9M+22.7%$541.2M-5.9%$575.2M-3.9%$598.3M
Retained Earnings-$123.1M-177.3%-$44.4M-353.9%-$9.8M-128.8%$33.9M-57.2%$79.3M+191.8%-$86.4M-169.3%$124.6M-19.7%$155.2M

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

ITOS Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ITOS quarterly cash flow statement
MetricQ2'25Q1'25Q4'24Q3'24Q2'24Q1'24Q4'23Q3'23
Operating Cash Flow-$42.4M-25.7%-$33.8M-714.2%$5.5M+114.7%-$37.4M-10.1%-$33.9M-4.7%-$32.4M-135.4%-$13.8M+59.4%-$33.9M
Capital Expenditures$283K+180.2%$101K-33.6%$152K+61.7%$94K-78.7%$442K-53.2%$945K-32.3%$1.4M+85.9%$751K
Free Cash Flow-$42.7M-26.2%-$33.9M-733.6%$5.3M+114.3%-$37.4M-8.9%-$34.4M-3.1%-$33.3M-119.9%-$15.2M+56.2%-$34.6M
Investing Cash Flow$87.0M+82.3%$47.7M+250.2%$13.6M+114.9%-$91.5M-660.5%$16.3M+123.5%-$69.6M-213.1%$61.6M+171.3%$22.7M
Financing Cash Flow$4.5M+13940.6%$32K-88.8%$285K+164.5%-$442K-100.4%$122.4M+556154.5%$22K-92.8%$307K+2970.0%$10K

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

ITOS Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

ITOS quarterly financial ratios
MetricQ2'25Q1'25Q4'24Q3'24Q2'24Q1'24Q4'23Q3'23
Operating MarginN/AN/AN/AN/A-40.5%N/AN/AN/A
Net MarginN/AN/AN/AN/A-20.4%N/AN/AN/A
Return on Equity-15.9%-9.8pp-6.1%N/A-7.2%-6.1pp-1.1%+6.0pp-7.1%N/A-5.4%
Return on Assets-12.6%-7.4pp-5.3%N/A-6.3%-5.3pp-0.9%+5.1pp-6.1%N/A-4.8%
Current Ratio7.53-6.6x14.13+1.5x12.62-2.2x14.80-3.3x18.08+4.6x13.51-0.3x13.76-8.2x21.94
Debt-to-Equity0.26+0.1x0.170.0x0.160.0x0.140.0x0.130.0x0.160.0x0.160.0x0.13
FCF MarginN/AN/AN/AN/A-98.2%N/AN/AN/A

Not reported in any period shown, so not listed: Gross Margin.

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Frequently Asked Questions

What is Iteos Therapeutics, Inc.'s annual revenue?

Iteos Therapeutics, Inc. (ITOS) reported $35.0M in total revenue for fiscal year 2024. This represents a 177.9% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Iteos Therapeutics, Inc.'s revenue growing?

Iteos Therapeutics, Inc. (ITOS) revenue grew by 177.9% year-over-year, from $12.6M to $35.0M in fiscal year 2024.

Is Iteos Therapeutics, Inc. profitable?

No, Iteos Therapeutics, Inc. (ITOS) reported a net income of -$134.4M in fiscal year 2024.

Iteos Therapeutics, Inc. (ITOS) reported diluted earnings per share of -$3.32 for fiscal year 2024. This represents a -5.4% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Iteos Therapeutics, Inc. (ITOS) had EBITDA of -$158.3M in fiscal year 2024, measuring earnings before interest, taxes, depreciation, and amortization.

Iteos Therapeutics, Inc. (ITOS) has a return on equity of -22.8% for fiscal year 2024, measuring how efficiently the company generates profit from shareholder equity.

Iteos Therapeutics, Inc. (ITOS) recorded an outflow of $99.8M in free cash flow during fiscal year 2024. This represents a 6.5% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Iteos Therapeutics, Inc. (ITOS) recorded an outflow of $98.2M in operating cash flow during fiscal year 2024, representing cash used by core business activities.

Iteos Therapeutics, Inc. (ITOS) had $687.0M in total assets as of fiscal year 2024, including both current and long-term assets.

Iteos Therapeutics, Inc. (ITOS) invested $1.6M in capital expenditures during fiscal year 2024, funding long-term assets and infrastructure.

Iteos Therapeutics, Inc. (ITOS) invested $145.4M in research and development during fiscal year 2024.

Iteos Therapeutics, Inc. (ITOS) had 38M shares outstanding as of fiscal year 2024.

Iteos Therapeutics, Inc. (ITOS) had a current ratio of 12.62 as of fiscal year 2024, which is generally considered healthy.

Iteos Therapeutics, Inc. (ITOS) had a debt-to-equity ratio of 0.16 as of fiscal year 2024, measuring the company's financial leverage by comparing total debt to shareholder equity.

Iteos Therapeutics, Inc. (ITOS) had a return on assets of -19.6% for fiscal year 2024, measuring how efficiently the company uses its assets to generate profit.

At the end of fiscal year 2024, Iteos Therapeutics, Inc. (ITOS) held $655.0M in cash, cash equivalents and investments, and reported an operating cash outflow of $98.2M over that year. Dividing the one by the other, the reported balance equals about 80 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Iteos Therapeutics, Inc. (ITOS) has an Altman Z-Score of 2.87, placing it in the Grey Zone (moderate risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Iteos Therapeutics, Inc. (ITOS) has a Piotroski F-Score of 2 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Iteos Therapeutics, Inc. (ITOS) reported a net loss of $134.4M while operations used $98.2M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Iteos Therapeutics, Inc. (ITOS) scores 34 out of 100 on our Financial Health Score, indicating weak standing within its operating companies peer group. The score is a 0-100 composite of six dimensions (Profitability, Growth, Leverage, Liquidity, Cash Flow, Returns), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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