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Lexeo Therapeutics, Inc. (LXEO) Financials

LXEO
FY2025 annual
Net Income -$100.0M -1.7% YoY
EPS (Diluted) -$1.86 YoY not available
Free Cash Flow -$99.0M -21.2% YoY
Operating Cash Flow -$98.6M -21.5% YoY
Market Cap $216.7M as of Oct 17, 2026
Price / Sales n/m no revenue reported
Price / Earnings n/m net loss, so no earnings multiple, FY2025
Price / Book 0.9x on $235.1M equity, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 17, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 12, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the LXEO SEC filings page.

This page shows Lexeo Therapeutics, Inc. (LXEO) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 4 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI LXEO FY2025

Lexeo remains a research-led business: operations consume cash, while new financing—not sales—has expanded its balance sheet.

In FY2025, the net loss of $100M closely matched operating cash outflow of $98.6M, indicating that reported losses are translating into immediate cash use rather than being driven mainly by non-cash charges. Meanwhile, financing cash flow supplied $216.8M as assets rose to $268.7M, so the larger balance sheet reflects capital raised more than internally generated funds.

The company is funding development before establishing a meaningful sales base: FY2022 R&D spending was $49.2M against reported revenue of only $654K, and later periods contain no reported revenue figure. That makes research spending, rather than gross-margin economics, the clearest lens for understanding operations.

The cost structure shifted toward corporate overhead: R&D was 1.4x SG&A in FY2025 versus 2.3x in FY2024, even as the annual net loss remained near $100M. The balance sheet is less debt-dependent than before, with debt-to-equity falling from 0.3x to 0.1x, while the reported liquidity measure equaled 30 months of annual operating outflow.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

Lexeo Therapeutics, Inc. does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Piotroski F-Score Partial
3/6

Lexeo Therapeutics, Inc. passes 3 of 6 computable financial strength tests (3 of the nine could not be computed from available data). 2 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass.

Earnings Quality No Cash Backing
N/A

Lexeo Therapeutics, Inc. reported a net loss of $100.0M while operations used $98.6M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Lexeo Therapeutics, Inc. reported an operating loss of $109.3M against $95K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

EBITDA
-$27.9M
YoY+8.8%
QoQ-25.5%

Lexeo Therapeutics, Inc.'s EBITDA was -$27.9M in Q2 2026, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 8.8% from the same quarter a year earlier. Against the prior quarter it is down 25.5%.

Net Income
-$25.9M
YoY+0.9%
QoQ-28.1%

Lexeo Therapeutics, Inc. reported -$25.9M in net income in Q2 2026. This represents an increase of 0.9% from the same quarter a year earlier. Against the prior quarter it is down 28.1%.

EPS (Diluted)
-$0.30
QoQ-20.0%

Lexeo Therapeutics, Inc. earned -$0.30 per diluted share (EPS) in Q2 2026. Against the prior quarter it is down 20.0%.

Revenue

Not reported for Q2 2026.

Cash & Balance Sheet

Free Cash Flow
-$17.6M
QoQ+16.9%

Lexeo Therapeutics, Inc. recorded an outflow of $17.6M in free cash flow in Q2 2026, representing a cash shortfall after capex. Against the prior quarter it is up 16.9%.

Cash & Debt
$92.8M
YoY+161.7%
QoQ+29.4%

Lexeo Therapeutics, Inc. held $92.8M in cash as of Q2 2026; long-term debt is not reported for that period.

Shares Outstanding
82M
QoQ+4.5%

Lexeo Therapeutics, Inc. had 82M shares outstanding in Q2 2026. Against the prior quarter it is up 4.5%.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Return on Equity
-11.0%
YoY+7.9pp
QoQ-2.3pp

Lexeo Therapeutics, Inc.'s ROE was -11.0% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is up 7.9 percentage points from the same quarter a year earlier. Against the prior quarter it is down 2.3 percentage points.

Gross Margin

Not reported for Q2 2026.

Operating Margin

Not reported for Q2 2026.

Net Margin

Not reported for Q2 2026.

Capital Allocation

R&D Spending
$19.0M
YoY+29.3%
QoQ+21.2%

Lexeo Therapeutics, Inc. invested $19.0M in research and development in Q2 2026. This represents an increase of 29.3% from the same quarter a year earlier. Against the prior quarter it is up 21.2%.

Capital Expenditures
$7K
QoQ-80.0%

Lexeo Therapeutics, Inc. invested $7K in capex in Q2 2026, funding long-term assets and infrastructure. Against the prior quarter it is down 80.0%.

Share Buybacks

Not reported for Q2 2026.

LXEO Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

LXEO quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
R&D Expenses$19.0M+29.3%$15.7M-8.5%N/A$15.7M-33.0%$14.7M-11.1%$17.2M+9.1%N/A$23.4M+35.8%
SG&A Expenses$9.0M-43.7%$6.6M-60.1%N/A$6.0M-26.7%$16.0M+128.4%$16.6M+120.3%N/A$8.1M+168.3%
Operating Income-$28.0M+8.7%-$22.3M+33.9%N/A-$21.6M+31.4%-$30.7M-30.3%-$33.8M-45.1%N/A-$31.5M-55.6%
EBITDA-$27.9M+8.8%-$22.3M+34.0%N/A-$21.6M+31.4%-$30.6M-30.5%-$33.7M-45.3%N/A-$31.5M-55.8%
Interest Expense$14K-44.0%$17K-39.3%N/A$22K-37.1%$25K-28.6%$28K-24.3%N/A$35K-32.7%
Net Income-$25.9M+0.9%-$20.2M+38.2%N/A-$20.3M+31.2%-$26.1M-22.9%-$32.7M-50.6%N/A-$29.5M-46.7%
EPS (Basic)-$0.30+50.0%-$0.25+74.7%-$0.14+82.1%-$0.33+62.9%-$0.60+6.3%-$0.99-28.6%-$0.78-103.9%-$0.89+92.8%
EPS (Diluted)-$0.30-$0.25-$0.14-$0.33-$0.60+6.3%-$0.99-28.6%-$0.78-103.9%-$0.89
Diluted Shares (Avg)86M81MN/A61M44M+32.0%33M+18.3%N/A33M

Not reported in any period shown, so not listed: Revenue, Cost of Revenue, Gross Profit, Income Tax.

LXEO Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

LXEO quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$254.9M+44.8%$250.4M+99.2%$268.7M+82.9%$143.8M-17.3%$176.1M-8.3%$125.7M-41.0%$146.9M+5.1%$173.9M+217.7%
Current Assets$217.9M+55.6%$200.9M+90.8%$188.4M+49.4%$127.8M-19.9%$140.1M-20.9%$105.3M-46.9%$126.1M+1.5%$159.5M+310.2%
Cash & Equivalents$92.8M+161.7%$71.8M+148.2%$63.0M+79.9%$41.0M-73.9%$35.5M-79.7%$28.9M-85.2%$35.0M-71.2%$157.0M+342.9%
Short-Term Investments$118.9M+22.0%$121.3M+71.0%$118.8M+37.3%$81.8M$97.4M$70.9M$86.5M$0
Long-Term Investments$22.5M+14.6%$34.5M+390.5%$64.8M+824.1%$0$19.6M$7.0M$7.0M$0
Total Liabilities$19.8M-47.6%$18.9M-49.8%$22.0M-26.8%$23.0M-33.4%$37.9M+39.9%$37.6M+24.2%$30.1M+14.6%$34.5M-84.1%
Current Liabilities$15.7M-50.3%$14.2M-54.0%$16.8M-26.4%$17.3M-35.6%$31.6M+67.4%$30.8M+42.5%$22.8M+32.5%$26.8M+16.4%
Non-Current Liabilities$4.1M-33.8%$4.7M-30.8%$5.2M-28.2%$5.7M-25.6%$6.3M-23.5%$6.8M-21.7%$7.3M-19.7%$7.7M-96.0%
Total Equity$235.1M+70.1%$231.5M+162.7%$246.7M+111.1%$120.8M-13.3%$138.2M-16.2%$88.1M-51.8%$116.8M+2.9%$139.3M+185.6%
Retained Earnings-$426.2M-25.7%-$400.3M-28.0%-$380.1M-35.7%-$359.2M-41.3%-$338.9M-50.8%-$312.8M-39.2%-$280.2M-54.1%-$254.2M-51.7%

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

LXEO Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

LXEO quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow-$17.6M+35.4%-$21.1M+2.6%-$20.1M+29.1%-$29.5M-65.9%-$27.2M-35.1%-$21.7M-46.1%-$28.3M-102.6%-$17.8M-27.7%
Depreciation & Amortization$74K+19.4%$73K+21.7%$73K-2.7%$73K-12.0%$62K-19.5%$60K-13.0%$75K-2.6%$83K+6.4%
Stock-Based Compensation$5.7M+85.3%$2.8M-25.5%N/A$2.7M-30.1%$3.1M+7.9%$3.7M+58.6%N/A$3.8M+333.1%
Capital Expenditures$7K$35K$0$289K+248.2%N/AN/A$0-100.0%$83K+2666.7%
Free Cash Flow-$17.6M-$21.2M-$20.1M+29.1%-$29.8M-66.8%N/AN/A-$28.3M-101.6%-$17.9M-28.2%
Investing Cash Flow$14.3M+136.4%$27.5M+76.0%-$101.7M-8.7%$35.0M+42281.9%-$39.2M-17869.7%$15.6M+8182.9%-$93.6M-128095.9%-$83K-56.6%
Financing Cash Flow$24.4M-66.6%$2.5M+22190.9%$143.8M+148318.6%$52K+172.2%$73.0M+24972.2%$11K-100.0%-$97K-100.1%-$72K-101.8%

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

LXEO Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

LXEO quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Return on Equity-11.0%+7.9pp-8.7%+28.3ppN/A-16.8%+4.4pp-18.9%-6.0pp-37.1%-25.2ppN/A-21.2%
Return on Assets-10.2%+4.7pp-8.1%+17.9ppN/A-14.1%+2.9pp-14.8%-3.8pp-26.0%-15.8ppN/A-17.0%+19.8pp
Current Ratio13.89+9.5x14.16+10.7x11.21+5.7x7.40+1.5x4.43-5.0x3.42-5.7x5.52-1.7x5.95+4.3x
Debt-to-Equity0.08-0.2x0.08-0.3x0.09-0.2x0.19-0.1x0.27+0.1x0.43+0.3x0.260.0x0.25

Not reported in any period shown, so not listed: Gross Margin, Operating Margin, Net Margin, Asset Turnover, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
Lexeo Therapeutics, Inc. LXEO FY2025 N/A -$100.0M N/A $216.7M —
Monopar Therapeutics Inc. MNPR FY2025 $0 -$13.7M N/A $465.0M —
Omeros Corporation OMER FY2025 N/A N/A N/A $1.2B —
Capricor Therapeutics Inc CAPR FY2025 $0 -$105.0M N/A $390.1M —
Alector, Inc. ALEC FY2025 $21.0M -$143.0M N/A $205.4M 49/100
Mereo BioPharma Group plc MREO FY2025 $500K $41.9M N/A $48.4M —

Frequently Asked Questions

Is Lexeo Therapeutics, Inc. profitable?

No, Lexeo Therapeutics, Inc. (LXEO) reported a net income of -$100.0M in fiscal year 2025.

What is Lexeo Therapeutics, Inc.'s earnings per share (EPS)?

Lexeo Therapeutics, Inc. (LXEO) reported diluted earnings per share of -$1.86 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

What is Lexeo Therapeutics, Inc.'s EBITDA?

Lexeo Therapeutics, Inc. (LXEO) had EBITDA of -$109.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Lexeo Therapeutics, Inc. (LXEO) has a return on equity of -40.5% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Lexeo Therapeutics, Inc. (LXEO) recorded an outflow of $99.0M in free cash flow during fiscal year 2025. This represents a -21.2% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Lexeo Therapeutics, Inc. (LXEO) recorded an outflow of $98.6M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Lexeo Therapeutics, Inc. (LXEO) had $268.7M in total assets as of fiscal year 2025, including both current and long-term assets.

Lexeo Therapeutics, Inc. (LXEO) invested $397K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Lexeo Therapeutics, Inc. (LXEO) invested $63.8M in research and development during fiscal year 2025.

Lexeo Therapeutics, Inc. (LXEO) had 74M shares outstanding as of fiscal year 2025.

Lexeo Therapeutics, Inc. (LXEO) had a current ratio of 11.21 as of fiscal year 2025, which is generally considered healthy.

Lexeo Therapeutics, Inc. (LXEO) had a debt-to-equity ratio of 0.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Lexeo Therapeutics, Inc. (LXEO) had a return on assets of -37.2% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Lexeo Therapeutics, Inc. (LXEO) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (FY2025). The market capitalization is $216.7M as of Oct 17, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

Lexeo Therapeutics, Inc. (LXEO) has no price-to-sales ratio at the moment: no revenue reported. The market capitalization is $216.7M as of Oct 17, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, Lexeo Therapeutics, Inc. (LXEO) held $246.6M in cash, cash equivalents and investments, and reported an operating cash outflow of $98.6M over that year. Dividing the one by the other, the reported balance equals about 30 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Lexeo Therapeutics, Inc. (LXEO) has a Piotroski F-Score of 3 out of 6 computable signals; 3 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Lexeo Therapeutics, Inc. (LXEO) reported a net loss of $100.0M while operations used $98.6M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Lexeo Therapeutics, Inc. (LXEO) reported an operating loss of $109.3M against $95K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

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