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Sutro Biopharma Financials

STRO
Trailing 12 months to June 30, 2026
Revenue $45.7M -56.3% YoY
Net Income -$180.6M +13.3% YoY
EPS (Diluted) -$22.49 FY2025 annual
Free Cash Flow Not reported for the trailing 12 months
Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Sutro Biopharma (STRO) reported $45.7M in revenue over the twelve months to Jun 30, 2026, down 56.3% from the prior twelve months. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 10 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI STRO FY2025

Sutro's dominant mechanic is development spending that continues to consume cash despite partial revenue and loss recovery.

Revenue recovery moved from $62.0M in FY2024 to $102.5M in FY2025, yet operating cash flow remained negative. The operating loss narrowed to -$158.4M while operating cash flow was -$177.2M, showing that accounting improvement still did not produce cash.

R&D fell from $252.0M to $166.4M, yet it still exceeded FY2025 revenue, keeping the model dependent on development spending rather than commercial scale. Operating margin improved from -384.3% to -154.5%, but remained negative; the recovery therefore reflects lower expense intensity, not profitable operating leverage.

At FY2025, total liabilities of $306.3M exceeded total assets of $173.8M, leaving negative equity and making balance-sheet structure more consequential than revenue margins. Current ratio was 2.0x, while reported liquidity equaled 9.6 months of latest annual operating outflow, indicating limited short-term flexibility without implying operating self-funding.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 48 / 100
Financial Health Score 48/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Sutro Biopharma's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
27
Dilution
84
R&D Intensity
87
Revenue Progress
24
Burn Trend
23
Balance Sheet
43
Altman Z-Score Distress
-9.11

Sutro Biopharma scores -9.11, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($339.1M) relative to total liabilities ($306.3M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
3/7

Sutro Biopharma passes 3 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Sutro Biopharma reported a net loss of $191.0M while operations used $177.2M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$102.5M
YoY+65.2%
5Y CAGR+19.1%

Sutro Biopharma generated $102.5M in revenue in fiscal year 2025. This represents an increase of 65.2% from the prior year.

EBITDA
-$151.0M
YoY+34.7%

Sutro Biopharma's EBITDA was -$151.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 34.7% from the prior year.

Net Income
-$191.0M
YoY+15.9%

Sutro Biopharma reported -$191.0M in net income in fiscal year 2025. This represents an increase of 15.9% from the prior year.

EPS (Diluted)
-$22.49

Sutro Biopharma earned -$22.49 per diluted share (EPS) in fiscal year 2025.

Cash & Balance Sheet

Cash & Debt
$58.1M
YoY-69.5%
5Y CAGR-22.4%

Sutro Biopharma held $58.1M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
17M

Sutro Biopharma had 17M shares outstanding in fiscal year 2025.

Free Cash Flow

Not reported for fiscal year 2025.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Return on Equity

Not reported for fiscal year 2025.

Capital Allocation

R&D Spending
$166.4M
YoY-34.0%
5Y CAGR+16.7%

Sutro Biopharma invested $166.4M in research and development in fiscal year 2025. This represents a decrease of 34.0% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

Capital Expenditures

Not reported for fiscal year 2025.

STRO Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

STRO quarterly income statement
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Revenue$9.8M-32.3%$14.5M+24.7%$11.6M+20.2%$9.7M-84.8%$63.7M+266.4%$17.4M+17.5%$14.8M+73.8%$8.5M
R&D Expenses$31.7M-13.3%$36.6M-0.2%$36.6M-8.1%$39.9M+4.0%$38.3M-25.7%$51.6M-27.4%$71.0M+14.4%$62.1M
SG&A Expenses$7.8M+3.3%$7.6M-12.4%$8.7M-0.9%$8.7M-15.5%$10.3M-22.1%$13.3M+47.0%$9.0M-37.0%$14.3M
Operating Income-$29.9M-0.8%-$29.7M+22.1%-$38.0M+21.5%-$48.5M-1348.7%-$3.3M+95.1%-$68.5M-5.0%-$65.3M+3.9%-$67.9M
Income Tax$1K+106.7%-$15K+81.7%-$82K$0+100.0%-$18K-357.1%$7KN/A$0
Net Income-$38.5M-0.1%-$38.5M+17.6%-$46.7M+17.9%-$56.9M-394.5%-$11.5M+84.9%-$76.0M-5.5%-$72.0M-47.5%-$48.8M
EPS (Diluted)-$2.33+20.7%-$2.94-$20.78-$0.67-$1.35+85.1%-$9.08-$0.89-50.8%-$0.59

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Interest Expense.

STRO Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

STRO quarterly balance sheet
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Total Assets$194.5M-19.6%$242.0M+39.2%$173.8M-17.1%$209.7M-20.1%$262.4M-18.4%$321.4M-17.0%$387.2M-14.3%$451.8M
Current Assets$175.6M-20.5%$221.0M+46.4%$150.9M-17.1%$182.1M-21.4%$231.6M-19.4%$287.4M-16.3%$343.3M-15.4%$405.8M
Cash & Equivalents$54.3M-26.3%$73.7M+26.8%$58.1M-11.8%$65.9M+3.0%$64.0M-39.7%$106.2M-44.2%$190.3M+9.0%$174.6M
Accounts Receivable$5.8M-53.6%$12.5M+213.9%$4.0M+1.4%$3.9M-51.0%$8.0M-41.0%$13.6M+57.4%$8.6M+29.5%$6.7M
Total Liabilities$297.8M-3.6%$308.9M+0.8%$306.3M+3.2%$296.9M+0.8%$294.5M-15.2%$347.2M+1.4%$342.6M+0.6%$340.6M
Current Liabilities$52.9M-25.3%$70.8M-5.8%$75.1M+4.5%$71.9M-3.2%$74.2M-44.2%$133.0M+0.9%$131.9M+0.5%$131.3M
Total Equity-$103.3M-54.5%-$66.9M+49.5%-$132.5M-51.8%-$87.3M-171.8%-$32.1M-24.4%-$25.8M-157.9%$44.6M-59.9%$111.2M
Retained Earnings-$1.1B-3.8%-$1.0B-3.9%-$978.0M-5.0%-$931.2M-6.5%-$874.3M-1.3%-$862.8M-9.7%-$786.9M-10.1%-$714.4M

Not reported in any period shown, so not listed: Inventory, Goodwill, Long-Term Debt.

STRO Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

STRO quarterly cash flow statement
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Operating Cash Flow-$38.3M+9.4%-$42.3M-59.9%-$26.4M+30.8%-$38.2M+14.6%-$44.7M+34.1%-$67.9M+5.4%-$71.7M-11.2%-$64.5M
Investing Cash Flow$19.4M+142.8%-$45.3M-342.0%$18.7M-53.2%$40.0M+1450.0%$2.6M+115.9%-$16.3M-118.6%$87.5M-40.6%$147.3M
Financing Cash Flow-$418K-100.4%$103.1M+161154.7%-$64K-162.7%$102K+270.0%-$60K-190.9%$66K+375.0%-$24K-102.4%$1.0M

Not reported in any period shown, so not listed: Capital Expenditures, Free Cash Flow, Dividends Paid, Share Buybacks.

STRO Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

STRO quarterly financial ratios
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Operating Margin-303.8%-204.2%-326.7%-499.9%-5.3%-393.8%-440.7%-797.2%
Net Margin-391.6%-265.0%-400.8%-586.6%-18.0%-436.6%-486.1%-572.6%
Return on EquityN/AN/AN/AN/AN/AN/A-161.4%-117.5pp-43.9%
Return on Assets-19.8%-3.9pp-15.9%+11.0pp-26.9%+0.3pp-27.1%-22.7pp-4.4%+19.3pp-23.6%-5.0pp-18.6%-7.8pp-10.8%
Current Ratio3.32+0.2x3.12+1.1x2.01-0.5x2.53-0.6x3.12+1.0x2.16-0.4x2.60-0.5x3.09
Debt-to-EquityN/AN/AN/AN/AN/AN/A7.68+4.6x3.06

Not reported in any period shown, so not listed: Gross Margin, FCF Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin.

Note: Shareholder equity is negative (-$132.5M), which causes debt-to-equity and return on equity ratios to appear negative or not meaningful. This can occur from accumulated losses or large share buyback programs.

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Frequently Asked Questions

What is Sutro Biopharma's annual revenue?

Sutro Biopharma (STRO) reported $102.5M in total revenue for fiscal year 2025. This represents a 65.2% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Sutro Biopharma's revenue growing?

Sutro Biopharma (STRO) revenue grew by 65.2% year-over-year, from $62.0M to $102.5M in fiscal year 2025.

Is Sutro Biopharma profitable?

No, Sutro Biopharma (STRO) reported a net income of -$191.0M in fiscal year 2025.

Sutro Biopharma (STRO) reported diluted earnings per share of -$22.49 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Sutro Biopharma (STRO) had EBITDA of -$151.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Sutro Biopharma (STRO) recorded an outflow of $177.2M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Sutro Biopharma (STRO) had $173.8M in total assets as of fiscal year 2025, including both current and long-term assets.

Sutro Biopharma (STRO) invested $166.4M in research and development during fiscal year 2025.

Sutro Biopharma (STRO) had 17M shares outstanding as of fiscal year 2025.

Sutro Biopharma (STRO) had a current ratio of 2.01 as of fiscal year 2025, which is generally considered healthy.

Sutro Biopharma (STRO) had a return on assets of -109.9% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

At the end of fiscal year 2025, Sutro Biopharma (STRO) held $141.4M in cash, cash equivalents and investments, and reported an operating cash outflow of $177.2M over that year. Dividing the one by the other, the reported balance equals about 10 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Sutro Biopharma (STRO) has negative shareholder equity of -$132.5M as of fiscal year 2025, so no debt-to-equity ratio is reported: dividing debt by equity that is not positive produces a number that cannot be read as leverage. This can occur when accumulated losses exceed invested capital, or after large share buyback programs. Other solvency metrics like the current ratio or interest coverage may be more informative.

Sutro Biopharma (STRO) has an Altman Z-Score of -9.11, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Sutro Biopharma (STRO) has a Piotroski F-Score of 3 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Sutro Biopharma (STRO) reported a net loss of $191.0M while operations used $177.2M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Sutro Biopharma (STRO) scores 48 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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