A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 8, 2026; every other figure is from the SEC filings on this page. Not financial advice.
Newest figures come from the 10-Q for Q2 FY2026, filed Aug 11, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the SYBX SEC filings page.
SYNLOGIC INC (SYBX) reported $0 in revenue for fiscal year 2025, down 100.0% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 13 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).
Synlogic’s reported numbers describe a development-stage business shrinking its research footprint, with losses and cash use falling as activity contracts.
R&D contraction took spending from$9.2M in FY2024 to$43K in FY2025, a sharper change than ordinary efficiency gains. Operating cash flow also improved from-$31.7M to-$4.4M ; because the spending base shrank simultaneously, the narrower loss reflects reduced activity rather than demonstrated sales economics.
FY2025’s current ratio was 4.3x and debt-to-equity was 0.3x, indicating near-term assets materially exceeded reported obligations without heavy debt financing. The reported liquidity comparison was 40.4 months of annual outflow, reinforcing that the balance sheet—not sales—was the immediate source of financial capacity.
Total assets fell from
Financial Health Signals
SYNLOGIC INC does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.
SYNLOGIC INC scores -37.80, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($13.5M) relative to total liabilities ($3.6M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.
Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.
SYNLOGIC INC passes 2 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, neither operating efficiency signal passes.
SYNLOGIC INC reported a net loss of $1.0M while operations used $4.4M of cash. With neither figure positive, the ratio between the two carries no quality signal.
Key Financial Metrics
Earnings & Revenue
SYNLOGIC INC generated $0 in revenue in Q2 2026.
SYNLOGIC INC reported -$543K in net income in Q2 2026. This represents a decrease of 2.6% from the same quarter a year earlier. Against the prior quarter it is down 179.7%.
SYNLOGIC INC earned -$0.04 per diluted share (EPS) in Q2 2026. That is unchanged from the same quarter a year earlier. Against the prior quarter it is down 180.0%.
Not reported for Q2 2026.
Cash & Balance Sheet
SYNLOGIC INC held $13.2M in cash as of Q2 2026; long-term debt is not reported for that period.
Not reported for Q2 2026.
Not reported for Q2 2026.
Margins & Returns
SYNLOGIC INC's ROE was -4.5% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is down 0.3 percentage points from the same quarter a year earlier. Against the prior quarter it is down 9.9 percentage points.
Not reported for Q2 2026.
Not reported for Q2 2026.
Not reported for Q2 2026.
Capital Allocation
None of these metrics is reported for Q2 2026.
SYBX Income Statement
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.
| Metric | Q2'2610-Q | Q1'2610-Q | Q4'2510-Q | Q3'2510-Q | Q2'2510-Q | Q1'2510-Q | Q4'2410-K | Q3'2410-Q |
|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | N/A | $0 | $0 | $0-100.0% | N/A | $0-100.0% |
| R&D Expenses | N/A | $49K+122.7% | N/A | N/A | N/A | $22K-99.7% | N/A | N/A |
| SG&A Expenses | $828K+3.5% | $1.1M+27.3% | N/A | $818K-29.8% | $800K-32.1% | $836K-71.0% | N/A | $1.2M-65.7% |
| Operating Income | -$1.0M-30.2% | -$1.3M-46.9% | N/A | -$991K-32.5% | -$777K-285.4% | -$898K+97.7% | N/A | -$748K+94.1% |
| EBITDA | N/A | N/A | N/A | -$991K-32.5% | -$777K-285.4% | -$898K+97.7% | N/A | -$748K+93.9% |
| Interest Expense | N/A | N/A | N/A | N/A | N/A | N/A | N/A | $0 |
| Income Tax | N/A | N/A | N/A | $0 | $0-100.0% | N/A | N/A | $0-100.0% |
| Net Income | -$543K-2.6% | $681K+114.8% | N/A | -$2.3M-1866.7% | -$529K-117.2% | $317K+101.2% | N/A | -$117K+99.0% |
| EPS (Basic) | -$0.040.0% | $0.05+66.7% | $0.12+300.0% | -$0.19-1800.0% | -$0.04-116.0% | $0.03+101.4% | -$0.06+76.0% | -$0.01+99.6% |
| EPS (Diluted) | -$0.040.0% | $0.05+66.7% | $0.12+300.0% | -$0.19-1800.0% | -$0.04-116.0% | $0.03+101.4% | -$0.06+76.0% | -$0.01 |
| Diluted Shares (Avg) | 12M+0.8% | 12M+0.1% | N/A | 12M+0.8% | 12M-0.6% | 12M+2.1% | N/A | 12M |
Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.
SYBX Balance Sheet
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.
| Metric | Q2'2610-Q | Q1'2610-Q | Q4'2510-Q | Q3'2510-Q | Q2'2510-Q | Q1'2510-Q | Q4'2410-K | Q3'2410-Q |
|---|---|---|---|---|---|---|---|---|
| Total Assets | $13.5M-22.4% | $14.6M-18.7% | $15.4M-22.1% | $16.6M-20.2% | $17.4M-19.7% | $18.0M-50.2% | $19.8M-73.8% | $20.8M-68.7% |
| Current Assets | $13.4M-22.5% | $14.6M-18.7% | $15.4M-22.1% | $16.5M-20.3% | $17.3M-19.7% | $17.9M-48.7% | $19.8M-60.4% | $20.7M-45.2% |
| Cash & Equivalents | $13.2M-22.6% | $14.1M-18.3% | $14.7M-22.2% | $15.6M-19.6% | $17.0M-14.7% | $17.3M-30.4% | $18.9M-21.3% | $19.4M-21.0% |
| Short-Term Investments | $0 | $0 | $0 | $0 | $0 | $0-100.0% | $0-100.0% | $0-100.0% |
| Long-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $1.5M-69.4% | $2.1M-57.8% | $3.6M-49.3% | $6.2M-18.5% | $4.8M-43.9% | $4.9M-81.7% | $7.1M-83.5% | $7.6M-66.5% |
| Current Liabilities | $1.5M-69.4% | $2.1M-57.8% | $3.6M-49.3% | $6.2M-18.5% | $4.8M-43.9% | $4.9M-67.2% | $7.1M-76.6% | $7.6M-16.4% |
| Non-Current Liabilities | $0 | $0 | $0 | $0 | $0 | $0-100.0% | $0-100.0% | $0-100.0% |
| Total Equity | $12.0M-4.6% | $12.6M-4.1% | $11.9M-7.0% | $10.3M-21.2% | $12.6M-4.0% | $13.1M+39.3% | $12.8M-61.1% | $13.1M-69.8% |
| Retained Earnings | -$442.5M-0.1% | -$442.0M-0.1% | -$442.7M-0.2% | -$444.2M-0.7% | -$441.9M-0.2% | -$441.3M+0.6% | -$441.7M-5.6% | -$440.9M-10.3% |
Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.
SYBX Cash Flow Statement
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.
| Metric | Q2'2610-Q | Q1'2610-Q | Q4'2510-Q | Q3'2510-Q | Q2'2510-Q | Q1'2510-Q | Q4'2410-K | Q3'2410-Q |
|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -$922K-131.1% | -$563K+64.8% | -$923K-62.5% | -$1.4M-121.6% | -$399K+97.3% | -$1.6M+89.6% | -$568K+89.7% | -$648K+95.0% |
| Depreciation & Amortization | N/A | N/A | $0 | $0 | $0 | $0-100.0% | $0-100.0% | $0-100.0% |
| Stock-Based Compensation | $6K-79.3% | $10K-60.0% | N/A | $33K-67.6% | $29K-94.2% | $25K-98.9% | N/A | $102K-84.1% |
| Capital Expenditures | N/A | N/A | $0 | $0 | $0-100.0% | $0-100.0% | $0-100.0% | $0 |
| Free Cash Flow | N/A | N/A | -$923K-62.5% | -$1.4M-121.6% | -$399K+97.4% | -$1.6M+89.9% | -$568K+89.8% | -$648K+95.0% |
| Investing Cash Flow | $0-100.0% | $0-100.0% | $0-100.0% | $0-100.0% | $155K-98.3% | $12K-99.9% | $30K+100.2% | $72K+100.8% |
| Financing Cash Flow | N/A | N/A | $0-100.0% | $0+100.0% | $0-100.0% | $0-100.0% | $9K-100.0% | -$1K-101.6% |
Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.
SYBX Financial Ratios
Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.
| Metric | Q2'2610-Q | Q1'2610-Q | Q4'2510-Q | Q3'2510-Q | Q2'2510-Q | Q1'2510-Q | Q4'2410-K | Q3'2410-Q |
|---|---|---|---|---|---|---|---|---|
| Return on Equity | -4.5%-0.3pp | 5.4%+3.0pp | N/A | -22.3%-21.4pp | -4.2%-27.6pp | 2.4%+274.9pp | N/A | -0.9%+26.9pp |
| Return on Assets | -4.0%-1.0pp | 4.7%+2.9pp | N/A | -13.9%-13.3pp | -3.0%-17.3pp | 1.8%+72.8pp | N/A | -0.6%+17.7pp |
| Current Ratio | 9.19+5.6x | 7.08+3.4x | 4.30+1.5x | 2.65-0.1x | 3.63+1.1x | 3.68+1.3x | 2.80+1.1x | 2.71-1.4x |
| Debt-to-Equity | 0.12-0.3x | 0.16-0.2x | 0.30-0.3x | 0.600.0x | 0.38-0.3x | 0.37-2.5x | 0.55-0.8x | 0.58+0.1x |
| Asset Turnover | 0.000.0x | 0.000.0x | N/A | 0.000.0x | 0.000.0x | 0.000.0x | N/A | 0.000.0x |
Not reported in any period shown, so not listed: Gross Margin, Operating Margin, Net Margin, FCF Margin.
Similar Companies
Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.
| Company | Fiscal year | Revenue | Net income | Net margin | Market cap | Health score |
|---|---|---|---|---|---|---|
| SYNLOGIC INC SYBX | FY2025 | $0 | -$1.0M | N/A | $13.5M | — |
| Pulmatrix, Inc. PULM | FY2025 | N/A | -$5.2M | N/A | $5.6M | — |
| Tharimmune, Inc. THAR | FY2025 | N/A | -$35.9M | N/A | $187.4M | — |
| MetaVia Inc. MTVA | FY2025 | N/A | -$13.0M | N/A | $8.8M | — |
| Lipocine Inc. LPCN | FY2025 | $2.0M | -$9.6M | N/A | $15.9M | 53/100 |
| CARISMA THERAPEUTICS INC CARM | FY2024 | $19.6M | -$60.5M | N/A | $6.4M | — |
Where SYNLOGIC INC Ranks
Frequently Asked Questions
What is SYNLOGIC INC's annual revenue?
SYNLOGIC INC (SYBX) reported $0 in total revenue for fiscal year 2025. This represents a -100.0% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.
How fast is SYNLOGIC INC's revenue growing?
SYNLOGIC INC (SYBX) revenue declined by 100.0% year-over-year, from $8K to $0 in fiscal year 2025.
Is SYNLOGIC INC profitable?
No, SYNLOGIC INC (SYBX) reported a net income of -$1.0M in fiscal year 2025.
What is SYNLOGIC INC's EBITDA?
SYNLOGIC INC (SYBX) had EBITDA of -$4.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.
What is SYNLOGIC INC's return on equity (ROE)?
SYNLOGIC INC (SYBX) has a return on equity of -8.5% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.
What is SYNLOGIC INC's free cash flow?
SYNLOGIC INC (SYBX) recorded an outflow of $4.4M in free cash flow during fiscal year 2025. This represents a 86.2% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.
What is SYNLOGIC INC's operating cash flow?
SYNLOGIC INC (SYBX) recorded an outflow of $4.4M in operating cash flow during fiscal year 2025, representing cash used by core business activities.
What are SYNLOGIC INC's total assets?
SYNLOGIC INC (SYBX) had $15.4M in total assets as of fiscal year 2025, including both current and long-term assets.
What are SYNLOGIC INC's capital expenditures?
SYNLOGIC INC (SYBX) reported no capital expenditure during fiscal year 2025.
How much does SYNLOGIC INC spend on research and development?
SYNLOGIC INC (SYBX) invested $43K in research and development during fiscal year 2025.
What is SYNLOGIC INC's current ratio?
SYNLOGIC INC (SYBX) had a current ratio of 4.30 as of fiscal year 2025, which is generally considered healthy.
What is SYNLOGIC INC's debt-to-equity ratio?
SYNLOGIC INC (SYBX) had a debt-to-equity ratio of 0.30 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.
What is SYNLOGIC INC's return on assets (ROA)?
SYNLOGIC INC (SYBX) had a return on assets of -6.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.
What is SYNLOGIC INC's P/E ratio?
SYNLOGIC INC (SYBX) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (FY2025). The market capitalization is $13.5M as of Oct 8, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.
What is SYNLOGIC INC's price-to-sales ratio?
SYNLOGIC INC (SYBX) has no price-to-sales ratio at the moment: revenue is not positive (FY2025). The market capitalization is $13.5M as of Oct 8, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.
How does SYNLOGIC INC's liquidity compare with its operating cash outflow?
At the end of fiscal year 2025, SYNLOGIC INC (SYBX) held $14.7M in cash, cash equivalents and investments, and reported an operating cash outflow of $4.4M over that year. Dividing the one by the other, the reported balance equals about 40 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.
What is SYNLOGIC INC's Altman Z-Score?
SYNLOGIC INC (SYBX) has an Altman Z-Score of -37.80, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.
What is SYNLOGIC INC's Piotroski F-Score?
SYNLOGIC INC (SYBX) has a Piotroski F-Score of 2 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.
Are SYNLOGIC INC's earnings high quality?
SYNLOGIC INC (SYBX) reported a net loss of $1.0M while operations used $4.4M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.