Synlogic Financials
Synlogic (SYBX) reported $0 in revenue for fiscal year 2025, down 100.0% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 13 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).
Cash preservation replaced development spending as Synlogic slashed research outlays and sharply narrowed cash burn.
The non-obvious shift is that loss reduction came from pulling back the cost base, not from building scale: R&D fell from$44.0M in FY2023 to$43K in FY2025. At the same time, operating cash burn dropped from-$51.6M to-$4.4M , and cash still exceeded liabilities in FY2025, so the company now looks structured more for preserving resources than for running a full research engine.
Capex reached
Liquidity improved faster than the cash balance alone suggests because total liabilities fell from
Financial Health Signals
Synlogic does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.
Synlogic scores -37.58, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($14.8M) relative to total liabilities ($3.6M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.
Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.
Synlogic passes 2 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, neither operating efficiency signal passes.
Synlogic reported a net loss of $1.0M while operations used $4.4M of cash. With neither figure positive, the ratio between the two carries no quality signal.
Key Financial Metrics
Earnings & Revenue
Synlogic generated $0 in revenue in fiscal year 2025. This represents a decrease of 100.0% from the prior year.
Synlogic's EBITDA was -$4.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 90.1% from the prior year.
Synlogic reported -$1.0M in net income in fiscal year 2025. This represents an increase of 95.7% from the prior year.
Synlogic earned -$0.08 per diluted share (EPS) in fiscal year 2025. This represents an increase of 95.8% from the prior year.
Cash & Balance Sheet
Synlogic recorded an outflow of $4.4M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents an increase of 86.2% from the prior year.
Synlogic held $14.7M in cash as of fiscal year 2025; long-term debt is not reported for that period.
Not reported for fiscal year 2025.
Margins & Returns
Synlogic's ROE was -8.5% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 174.7 percentage points from the prior year.
Not reported for fiscal year 2025.
Not reported for fiscal year 2025.
Not reported for fiscal year 2025.
Capital Allocation
Synlogic invested $43K in research and development in fiscal year 2025. This represents a decrease of 99.5% from the prior year.
Synlogic reported no capital expenditure in fiscal year 2025. This represents a decrease of 100.0% from the prior year.
Not reported for fiscal year 2025.
SYBX Income Statement
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.
| Metric | TTM | FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | FY19 | FY18 | FY17 | FY16 | FY15 | FY14 | FY13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | N/A | $0-100.0% | $8K-99.8% | $3.4M+185.7% | $1.2M-32.7% | $1.8M+221.8% | $545K-75.5% | $2.2M-11.7% | $2.5M+3.1% | $2.4M+450.5% | $444K | N/A | N/A | N/A |
| R&D Expenses | N/A | $43K-99.5% | $9.2M-79.2% | $44.0M-15.5% | $52.0M+10.4% | $47.1M-0.7% | $47.5M+13.3% | $41.9M+10.2% | $38.0M+25.4% | $30.3M+102.1% | $15.0M-20.8% | $18.9M+79.7% | $10.5M+140.2% | $4.4M |
| SG&A Expenses | N/A | $3.5M-47.4% | $6.6M-54.5% | $14.6M-12.0% | $16.6M+7.6% | $15.4M+13.7% | $13.5M-8.1% | $14.7M-6.3% | $15.7M+21.6% | $12.9M+102.0% | $6.4M+5.2% | $6.1M+80.5% | $3.4M+41.3% | $2.4M |
| Operating Income | N/A | -$4.0M+90.2% | -$41.0M+25.8% | -$55.2M+18.2% | -$67.4M-11.0% | -$60.8M-0.5% | -$60.5M-11.1% | -$54.4M-6.2% | -$51.2M-25.5% | -$40.8M-94.7% | -$21.0M | N/A | N/A | N/A |
| Interest Expense | N/A | N/A | $0-100.0% | $1K-50.0% | $2K0.0% | $2K-66.7% | $6K-71.4% | $21K-51.2% | $43K-24.6% | $57K+714.3% | $7K | N/A | N/A | N/A |
| Income Tax | N/A | $0-100.0% | $5K-64.3% | $14K | $0 | $0 | $0 | $0 | $0 | N/A | $0 | $0 | $0 | N/A |
| Net Income | N/A | -$1.0M+95.7% | -$23.4M+61.9% | -$61.3M+7.4% | -$66.1M-9.2% | -$60.6M-2.3% | -$59.2M-15.2% | -$51.4M-6.1% | -$48.4M-20.0% | -$40.4M-92.7% | -$21.0M+16.1% | -$25.0M-57.8% | -$15.8M-146.0% | -$6.4M |
| EPS (Diluted) | — | -$0.08+95.8% | -$1.92 | -$9.42 | -$13.83 | -$1.09 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.
TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.
SYBX Balance Sheet
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.
| Metric | FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | FY19 | FY18 | FY17 | FY16 | FY15 | FY14 | FY13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | $15.4M-22.1% | $19.8M-73.8% | $75.5M-31.9% | $110.9M-36.6% | $174.7M+21.5% | $143.8M-23.7% | $188.6M+34.4% | $140.3M+40.8% | $99.7M+397.5% | $20.0M-78.0% | $90.9M+825.4% | $9.8M | N/A |
| Current Assets | $15.4M-22.1% | $19.8M-60.4% | $49.9M-37.4% | $79.8M-40.2% | $133.3M+24.8% | $106.8M-19.8% | $133.2M+7.2% | $124.3M+40.4% | $88.6M+451.5% | $16.1M-82.3% | $90.5M+841.5% | $9.6M | N/A |
| Cash & Equivalents | $14.7M-22.2% | $18.9M-21.3% | $24.0M+51.1% | $15.9M-3.5% | $16.4M-49.4% | $32.5M+24.1% | $26.2M+132.7% | $11.3M-80.7% | $58.4M+300.7% | $14.6M-83.7% | $89.7M+862.7% | $9.3M-59.8% | $23.2M |
| Total Liabilities | $3.6M-49.3% | $7.1M-83.5% | $42.8M+51.4% | $28.3M+2.9% | $27.5M-4.3% | $28.7M-9.4% | $31.7M+95.0% | $16.2M+10.8% | $14.7M+27.1% | $11.5M-87.2% | $89.9M+55.7% | $57.8M | N/A |
| Current Liabilities | $3.6M-49.3% | $7.1M-76.6% | $30.3M+149.9% | $12.1M+20.3% | $10.1M+21.4% | $8.3M-6.3% | $8.9M+6.3% | $8.3M-7.6% | $9.0M+115.6% | $4.2M-29.1% | $5.9M+136.1% | $2.5M | N/A |
| Total Equity | $11.9M-7.0% | $12.8M-61.1% | $32.8M-60.3% | $82.6M-43.9% | $147.3M+27.9% | $115.1M-26.6% | $156.9M+26.4% | $124.1M+45.9% | $85.0M+900.1% | $8.5M+770.3% | $977K+102.0% | -$48.0M-60.3% | -$29.9M |
| Retained Earnings | -$442.7M-0.2% | -$441.7M-5.6% | -$418.3M-17.2% | -$357.0M-22.7% | -$290.9M-26.3% | -$230.3M-34.6% | -$171.1M-42.9% | -$119.8M-67.1% | -$71.7M-129.3% | -$31.2M+59.2% | -$76.5M-59.6% | -$48.0M | N/A |
Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.
SYBX Cash Flow Statement
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.
| Metric | TTM | FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | FY19 | FY18 | FY17 | FY16 | FY15 | FY14 | FY13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -$3.8M | -$4.4M+86.2% | -$31.7M+38.7% | -$51.6M+9.3% | -$56.9M-9.0% | -$52.2M-32.0% | -$39.6M+47.6% | -$75.5M-77.7% | -$42.5M-36.8% | -$31.1M-52.2% | -$20.4M+3.4% | -$21.1M-51.3% | -$14.0M-115.1% | -$6.5M |
| Capital Expenditures | N/A | $0-100.0% | $14K-93.5% | $214K-70.6% | $728K+7.2% | $679K+71.9% | $395K-68.4% | $1.3M-77.9% | $5.7M+119.3% | $2.6M+40.0% | $1.8M+633.5% | $251K+146.1% | $102K+1357.1% | $7K |
| Free Cash Flow | N/A | -$4.4M+86.2% | -$31.7M+38.9% | -$51.8M+10.0% | -$57.6M-9.0% | -$52.9M-32.4% | -$39.9M+47.9% | -$76.7M-59.4% | -$48.1M-43.1% | -$33.6M-51.2% | -$22.2M-4.0% | -$21.4M-52.0% | -$14.1M-116.4% | -$6.5M |
| Investing Cash Flow | $0 | $167K-99.3% | $25.3M-34.6% | $38.8M-33.6% | $58.4M+209.6% | -$53.3M-263.9% | $32.5M+200.9% | $10.8M+112.4% | -$87.2M-1039.9% | $9.3M | N/A | N/A | N/A | N/A |
| Financing Cash Flow | N/A | $0-100.0% | $172K-99.2% | $20.9M+1126.7% | -$2.0M-102.3% | $89.4M+567.3% | $13.4M-83.2% | $79.6M-3.5% | $82.5M+23.7% | $66.7M | N/A | N/A | N/A | N/A |
| Share Buybacks | N/A | N/A | N/A | $0-100.0% | $2.5M | $0 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
Not reported in any period shown, so not listed: Dividends Paid.
TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.
SYBX Financial Ratios
Margins and returns are percentages; the remaining ratios are unitless multiples.
| Metric | FY25 | FY24 | FY23 | FY22 | FY21 | FY20 | FY19 | FY18 | FY17 | FY16 | FY15 | FY14 | FY13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | N/A | -511875.0% | -1636.3% | -5713.5% | -3464.4% | -11094.7% | -2446.5% | -2032.9% | -1670.4% | -4721.6% | N/A | N/A | N/A |
| Net Margin | N/A | -291987.5% | -1817.7% | -5605.7% | -3452.7% | -10857.4% | -2309.9% | -1922.0% | -1652.1% | -4719.4% | N/A | N/A | N/A |
| Return on Equity | -8.5%+174.7pp | -183.2%+3.8pp | -187.0%-106.9pp | -80.1%-38.9pp | -41.1%+10.3pp | -51.4%-18.6pp | -32.7%+6.3pp | -39.0%+8.5pp | -47.5%+199.0pp | -246.4%+2310.7pp | -2557.1% | N/A | N/A |
| Return on Assets | -6.5%+111.3pp | -117.8%-36.7pp | -81.1%-21.4pp | -59.7%-25.0pp | -34.7%+6.5pp | -41.1%-13.9pp | -27.2%+7.3pp | -34.5%+6.0pp | -40.5%+64.1pp | -104.6%-77.1pp | -27.5%+133.7pp | -161.2% | N/A |
| Current Ratio | 4.30+1.5x | 2.80+1.1x | 1.65-4.9x | 6.58-6.6x | 13.23+0.4x | 12.87-2.2x | 15.03+0.1x | 14.91+5.1x | 9.81+6.0x | 3.84-11.5x | 15.34+11.5x | 3.85 | N/A |
| Debt-to-Equity | 0.30-0.3x | 0.55-0.8x | 1.31+1.0x | 0.34+0.2x | 0.19-0.1x | 0.250.0x | 0.20+0.1x | 0.130.0x | 0.17-1.2x | 1.36-90.7x | 92.06 | N/A | N/A |
| FCF Margin | N/A | -395900.0% | -1537.5% | -4882.7% | -3014.7% | -7329.9% | -3449.6% | -1909.7% | -1376.2% | -5011.0% | N/A | N/A | N/A |
Not reported in any period shown, so not listed: Gross Margin.
Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.
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Where Synlogic Ranks
Frequently Asked Questions
What is Synlogic's annual revenue?
Synlogic (SYBX) reported $0 in total revenue for fiscal year 2025. This represents a -100.0% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.
How fast is Synlogic's revenue growing?
Synlogic (SYBX) revenue declined by 100.0% year-over-year, from $8K to $0 in fiscal year 2025.
Is Synlogic profitable?
No, Synlogic (SYBX) reported a net income of -$1.0M in fiscal year 2025.
What is Synlogic's EBITDA?
Synlogic (SYBX) had EBITDA of -$4.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.
What is Synlogic's return on equity (ROE)?
Synlogic (SYBX) has a return on equity of -8.5% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.
What is Synlogic's free cash flow?
Synlogic (SYBX) recorded an outflow of $4.4M in free cash flow during fiscal year 2025. This represents a 86.2% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.
What is Synlogic's operating cash flow?
Synlogic (SYBX) recorded an outflow of $4.4M in operating cash flow during fiscal year 2025, representing cash used by core business activities.
What are Synlogic's total assets?
Synlogic (SYBX) had $15.4M in total assets as of fiscal year 2025, including both current and long-term assets.
What are Synlogic's capital expenditures?
Synlogic (SYBX) reported no capital expenditure during fiscal year 2025.
How much does Synlogic spend on research and development?
Synlogic (SYBX) invested $43K in research and development during fiscal year 2025.
What is Synlogic's current ratio?
Synlogic (SYBX) had a current ratio of 4.30 as of fiscal year 2025, which is generally considered healthy.
What is Synlogic's debt-to-equity ratio?
Synlogic (SYBX) had a debt-to-equity ratio of 0.30 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.
What is Synlogic's return on assets (ROA)?
Synlogic (SYBX) had a return on assets of -6.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.
What is Synlogic's Altman Z-Score?
Synlogic (SYBX) has an Altman Z-Score of -37.58, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.
What is Synlogic's Piotroski F-Score?
Synlogic (SYBX) has a Piotroski F-Score of 2 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.
Are Synlogic's earnings high quality?
Synlogic (SYBX) reported a net loss of $1.0M while operations used $4.4M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.