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Xencor Financials

XNCR
FY2025 annual
Revenue $125.6M +13.7% YoY
Net Income -$91.9M +60.5% YoY
EPS (Diluted) -$1.24 +65.4% YoY
Free Cash Flow -$138.3M +33.6% YoY
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Xencor (XNCR) reported $125.6M in revenue for fiscal year 2025, up 13.7% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 14 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI XNCR FY2025

Xencor’s visible mechanic is a research-heavy model financed by the balance sheet, with revenue not yet absorbing the cost base.

FY2025’s smaller net loss versus FY2024 did not come from healthier core economics: operating loss was still about -$177.5M, and operating cash flow was -$135.1M. That gap says the apparent earnings rebound was driven largely below the operating line, while cash burn still tracked the underlying loss-making engine.

The business is still internally unfunded: FY2025 revenue of $125.6M covered only about half of R&D expense at $239.4M, so reported sales are not yet carrying the research platform. That is why losses persist even when revenue rebounds slightly: the expense base is built for research progress, not current-period sales efficiency.

The balance sheet is doing the cushioning: current assets exceeded current liabilities by roughly $504M, and long-term debt was down to $76.5M, so the immediate constraint is burn rate more than leverage. Free cash flow at -$138.3M sat close to operating cash flow, so the cash drain comes mainly from running the business rather than from heavy capital spending.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 43 / 100
Financial Health Score 43/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Xencor's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
23
Dilution
48
R&D Intensity
97
Revenue Progress
27
Burn Trend
21
Balance Sheet
39
Altman Z-Score Safe
4.28

Xencor scores 4.28, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($2.2B) relative to total liabilities ($239.9M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
3/8

Xencor passes 3 of 8 computable financial strength tests (1 of the nine could not be computed from available data). 1 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Xencor reported a net loss of $91.9M while operations used $135.1M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Xencor reported an operating loss of $177.5M against $31.9M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$125.6M
YoY+13.7%
5Y CAGR+0.5%

Xencor generated $125.6M in revenue in fiscal year 2025. This represents an increase of 13.7% from the prior year.

EBITDA
-$167.0M
YoY-0.4%

Xencor's EBITDA was -$167.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 0.4% from the prior year.

Net Income
-$91.9M
YoY+60.5%

Xencor reported -$91.9M in net income in fiscal year 2025. This represents an increase of 60.5% from the prior year.

EPS (Diluted)
-$1.24
YoY+65.4%

Xencor earned -$1.24 per diluted share (EPS) in fiscal year 2025. This represents an increase of 65.4% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$138.3M
YoY+33.6%

Xencor recorded an outflow of $138.3M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents an increase of 33.6% from the prior year.

Cash & Debt
$54.1M
YoY+32.3%
5Y CAGR-19.9%
10Y CAGR+15.7%

Xencor held $54.1M in cash against $76.5M in long-term debt as of fiscal year 2025.

Shares Outstanding
72M
YoY+2.0%
5Y CAGR+4.4%
10Y CAGR+5.9%

Xencor had 72M shares outstanding in fiscal year 2025. This represents an increase of 2.0% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Net Margin
-73.2%
5Y CAGR-16.7pp

Xencor's net profit margin was -73.2% in fiscal year 2025, showing the share of revenue converted to profit. No change is given against fiscal year 2024: its reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Return on Equity
-14.5%
YoY+19.9pp
5Y CAGR-2.4pp
10Y CAGR-3.6pp

Xencor's ROE was -14.5% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 19.9 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$239.4M
YoY+5.2%
5Y CAGR+7.1%
10Y CAGR+21.5%

Xencor invested $239.4M in research and development in fiscal year 2025. This represents an increase of 5.2% from the prior year.

Capital Expenditures
$3.1M
YoY-48.3%
5Y CAGR-21.5%
10Y CAGR+5.0%

Xencor invested $3.1M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 48.3% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

XNCR Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

XNCR annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12
Revenue$105.0M$125.6M+13.7%$110.5M-36.7%$174.6M+6.1%$164.6M-40.2%$275.1M+124.2%$122.7M-21.7%$156.7M+285.9%$40.6M-12.0%$46.1M-57.7%$109.0MN/AN/AN/AN/A
R&D Expenses$255.8M$239.4M+5.2%$227.7M-10.2%$253.6M+27.1%$199.6M+3.7%$192.5M+13.4%$169.8M+43.2%$118.6M+21.6%$97.5M+35.8%$71.8M+38.4%$51.9M+51.9%$34.1M+84.4%$18.5M+8.9%$17.0M+34.2%$12.7M
SG&A Expenses$65.3M$63.6M+4.0%$61.2M+14.7%$53.4M+12.4%$47.5M+22.3%$38.8M+30.8%$29.7M+22.2%$24.3M+8.1%$22.5M+28.4%$17.5M+33.5%$13.1M+9.6%$12.0M+60.3%$7.5M+102.1%$3.7M+19.6%$3.1M
Operating Income-$216.1M-$177.5M+0.5%-$178.4M-34.8%-$132.4M-60.5%-$82.5M-288.4%$43.8M+157.0%-$76.8M-655.5%$13.8M+117.4%-$79.4M-84.1%-$43.1M-197.9%$44.0M+340.2%-$18.3M-11.4%-$16.5M-56.4%-$10.5M-68.9%-$6.2M
Interest Expense$27.1M$31.9M-12.9%$36.6M+493.2%$6.2M+47415.4%$13K0.0%$13K-99.8%$7.3M-46.7%$13.6M+85018.8%$16K+23.1%$13K-38.1%$21K+61.5%$13K+44.4%$9K-99.3%$1.2M-50.7%$2.5M
Income Tax$2.5M$2.5M+54.9%$1.6M-88.2%$13.7M+1930.0%$673K$0$0-100.0%$312K$0+100.0%-$463K-146.7%$991KN/AN/AN/AN/A
Net Income-$163.3M-$91.9M+60.5%-$232.6M-74.7%-$133.1M-141.3%-$55.2M-166.8%$82.6M+219.2%-$69.3M-358.0%$26.9M+138.2%-$70.4M-82.9%-$38.5M-185.3%$45.1M+356.5%-$17.6M-7.1%-$16.4M+72.7%-$60.3M-601.2%-$8.6M
EPS (Diluted)-$1.24+65.4%-$3.58-62.7%-$2.20-136.6%-$0.93-167.9%$1.37+213.2%-$1.21-363.0%$0.46+135.1%-$1.31-59.8%-$0.82-176.6%$1.07+337.8%-$0.45+13.5%-$0.52-$3.85-$118.86

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

XNCR Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

XNCR annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12
Total Assets$875.5M-8.0%$951.9M-1.4%$965.1M+14.0%$846.3M+1.0%$838.2M+19.2%$703.2M+4.9%$670.3M+16.2%$576.7M+47.8%$390.2M-9.0%$428.6M+107.1%$206.9M+205.1%$67.8M-22.3%$87.3MN/A
Current Assets$599.8M+3.8%$577.6M-9.1%$635.6M-5.9%$675.3M+59.1%$424.4M-33.5%$637.7M+14.2%$558.4M+76.9%$315.7M+36.7%$230.9M+63.0%$141.7M+45.0%$97.7M+69.1%$57.7M-26.1%$78.1MN/A
Cash & Equivalents$54.1M+32.3%$40.9M-24.0%$53.8M-0.3%$53.9M-62.4%$143.5M-12.3%$163.5M+225.1%$50.3M+91.7%$26.2M+58.8%$16.5M+13.8%$14.5M+15.4%$12.6M-77.0%$54.6M-29.9%$78.0M+3272.6%$2.3M
Accounts Receivable$29.3M-51.8%$60.8M+156.3%$23.7M-18.1%$29.0M-56.3%$66.4M+480.1%$11.4M-47.0%$21.6M+111.8%$10.2M+792.0%$1.1M-86.7%$8.6M+19481.8%$44K-98.5%$3.0M+4927.1%$59KN/A
Total Liabilities$239.9M-13.7%$277.9M-8.3%$303.0M+155.2%$118.8M+13.4%$104.7M-19.9%$130.8M+69.8%$77.0M+40.0%$55.1M-25.3%$73.7M-35.7%$114.6M+157.7%$44.5M+421.2%$8.5M-38.1%$13.8MN/A
Current Liabilities$95.9M+9.7%$87.4M+18.3%$73.9M+15.8%$63.8M-9.7%$70.7M-41.6%$121.1M+81.9%$66.6M+23.6%$53.9M-25.9%$72.7M-31.6%$106.3M+144.7%$43.4M+600.9%$6.2M-17.2%$7.5MN/A
Long-Term Debt$76.5M-33.6%$115.2M-28.8%$161.8M$0N/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Total Equity$635.6M-6.2%$677.6M+2.4%$661.8M-9.0%$727.5M-0.8%$733.5M+28.1%$572.4M-3.5%$593.2M+13.7%$521.7M+64.8%$316.5M-6.4%$337.9M+108.0%$162.4M+174.0%$59.3M-19.4%$73.5M+144.2%-$166.3M
Retained Earnings-$796.0M-13.1%-$704.0M-49.3%-$471.4M-39.4%-$338.3M-19.5%-$283.1M+22.6%-$365.7M-23.4%-$296.4M+8.3%-$323.3M-27.8%-$252.9M-6.3%-$238.0M+9.0%-$261.6M-7.2%-$244.0M-7.2%-$227.6MN/A

Not reported in any period shown, so not listed: Inventory, Goodwill.

XNCR Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

XNCR annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12
Operating Cash Flow-$205.8M-$135.1M+33.2%-$202.2M-159.5%-$77.9M-418.3%$24.5M+245.3%-$16.9M-236.8%-$5.0M-107.8%$64.4M+180.7%-$79.8M-137.4%-$33.6M-135.3%$95.2M+257.2%$26.7M+224.9%-$21.4M-291.5%-$5.5M+50.7%-$11.1M
Capital Expenditures$2.5M$3.1M-48.3%$6.1M-67.0%$18.4M-52.1%$38.5M+189.5%$13.3M+26.2%$10.5M+43.3%$7.4M+2.0%$7.2M+35.8%$5.3M+252.4%$1.5M-21.9%$1.9M+147.4%$780K+473.5%$136K+231.7%$41K
Free Cash Flow-$208.3M-$138.3M+33.6%-$208.3M-116.1%-$96.4M-587.9%-$14.0M+53.5%-$30.2M-94.0%-$15.5M-127.3%$57.0M+165.6%-$87.0M-123.5%-$38.9M-141.5%$93.7M+278.9%$24.7M+211.8%-$22.1M-296.0%-$5.6M+49.6%-$11.1M
Investing Cash Flow$197.6M$140.0M+1878.3%-$7.9M+92.9%-$111.1M+7.2%-$119.7M-158.9%-$46.2M-146.2%$100.2M+296.6%-$51.0M+69.1%-$164.8M-617.1%$31.9M+114.9%-$214.3M-15.8%-$185.1MN/AN/AN/A
Financing Cash Flow$8.3M$8.2M-95.8%$197.2M+4.2%$189.2M+3218.5%$5.7M-86.8%$43.0M+138.5%$18.0M+69.2%$10.7M-95.8%$254.2M+6710.6%$3.7M-96.9%$121.0M+3.9%$116.4MN/AN/AN/A

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

XNCR Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

XNCR annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12
Operating Margin-141.3%-161.5%-75.8%-25.7pp-50.1%-66.0pp15.9%+78.5pp-62.6%-71.4pp8.8%-195.5%-93.4%-133.8pp40.4%N/AN/AN/AN/A
Net Margin-73.2%-210.5%-76.2%-42.7pp-33.5%-63.6pp30.0%+86.6pp-56.5%-73.7pp17.2%-173.4%-83.4%-124.8pp41.4%N/AN/AN/AN/A
Return on Equity-14.5%+19.9pp-34.3%-14.2pp-20.1%-12.5pp-7.6%-18.9pp11.3%+23.4pp-12.1%-16.6pp4.5%+18.0pp-13.5%-1.3pp-12.2%-25.5pp13.4%+24.2pp-10.8%+16.9pp-27.7%+54.3pp-82.0%N/A
Return on Assets-10.5%+13.9pp-24.4%-10.7pp-13.8%-7.3pp-6.5%-16.4pp9.9%+19.7pp-9.9%-13.9pp4.0%+16.2pp-12.2%-2.4pp-9.9%-20.4pp10.5%+19.0pp-8.5%+15.7pp-24.2%+44.8pp-69.0%N/A
Current Ratio6.25-0.4x6.61-2.0x8.60-2.0x10.58+4.6x6.00+0.7x5.27-3.1x8.39+2.5x5.86+2.7x3.18+1.8x1.33-0.9x2.25-7.1x9.32-1.1x10.44N/A
Debt-to-Equity0.120.0x0.17-0.1x0.24+0.2x0.00-0.1x0.14-0.1x0.23+0.1x0.130.0x0.11-0.1x0.23-0.1x0.34+0.1x0.27+0.1x0.140.0x0.19N/A
FCF Margin-110.1%-188.5%-55.2%-46.7pp-8.5%+2.5pp-11.0%+1.7pp-12.7%-49.1pp36.4%-214.2%-84.3%-170.3pp86.0%N/AN/AN/AN/A

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Xencor's annual revenue?

Xencor (XNCR) reported $125.6M in total revenue for fiscal year 2025. This represents a 13.7% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Xencor's revenue growing?

Xencor (XNCR) revenue grew by 13.7% year-over-year, from $110.5M to $125.6M in fiscal year 2025.

Is Xencor profitable?

No, Xencor (XNCR) reported a net income of -$91.9M in fiscal year 2025, with a net profit margin of -73.2%.

Xencor (XNCR) reported diluted earnings per share of -$1.24 for fiscal year 2025. This represents a 65.4% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Xencor (XNCR) had EBITDA of -$167.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Xencor (XNCR) had $54.1M in cash and equivalents against $76.5M in long-term debt.

Xencor (XNCR) had a net profit margin of -73.2% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Xencor (XNCR) has a return on equity of -14.5% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Xencor (XNCR) recorded an outflow of $138.3M in free cash flow during fiscal year 2025. This represents a 33.6% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Xencor (XNCR) recorded an outflow of $135.1M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Xencor (XNCR) had $875.5M in total assets as of fiscal year 2025, including both current and long-term assets.

Xencor (XNCR) invested $3.1M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Xencor (XNCR) invested $239.4M in research and development during fiscal year 2025.

Xencor (XNCR) had 72M shares outstanding as of fiscal year 2025.

Xencor (XNCR) had a current ratio of 6.25 as of fiscal year 2025, which is generally considered healthy.

Xencor (XNCR) had a debt-to-equity ratio of 0.12 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Xencor (XNCR) had a return on assets of -10.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Xencor (XNCR) had $54.1M in cash against an annual operating cash burn of $135.1M. This gives an estimated cash runway of approximately 5 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Xencor (XNCR) has an Altman Z-Score of 4.28, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Xencor (XNCR) has a Piotroski F-Score of 3 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Xencor (XNCR) reported a net loss of $91.9M while operations used $135.1M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Xencor (XNCR) reported an operating loss of $177.5M against $31.9M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Xencor (XNCR) scores 43 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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