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Autonomix Medical Expands Precision Neuromodulation Platform with Broad New U.S. Patent Supporting Nerve Sensing, Mapping and Targeted Therapy

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Autonomix Medical (NASDAQ: AMIX) announced issuance of U.S. Patent No. 12,433,670, titled “Systems and Methods for Treating Cancer and/or Augmenting Organ Function.” The patent expands protection for minimally invasive technologies that sense, map and selectively target nerves linked to tumors, cancer-related pain, organ function and autonomic nervous system disorders.

The patent covers catheter-based microsurgical tools that record neural signals and deliver energy or therapeutic agents to block or modulate identified nerves. According to Autonomix Medical, it broadens the company’s precision neuromodulation platform and complements previously issued patents in autonomic assessment, neural sensing, treatment guidance and transvascular neuromodulation.

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Negative

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Market reaction after precision neuromodulation patent: AMIX +60.09%

+60.09% $5.84 5.6x vol
15m delay
+60.09% Vs previous close
+26.5% Peak Tracked
-6.4% Trough Tracked
$5.84 Last Price
$3.41 $7.43 Day Range
$2.99M Market Cap
5.6x Rel. Volume

Following this news, AMIX has gained 60.09%, reflecting a significant positive market reaction. Argus tracked a peak move of +26.5% during the session. Argus tracked a trough of -6.4% from its starting point during tracking. Our momentum scanner has triggered 71 alerts so far, indicating high trading interest and price volatility. The stock is currently trading at $5.84. Trading volume is exceptionally heavy at 5.6x the average, suggesting very strong buying interest.

Data tracked by StockTitan Argus (15 min delayed). Upgrade to Gold for real-time data.

Market Context

The stock is down -5.8% following this news. AMIX's July 23 patent announcement was followed by -12....
Analysis

The stock is down -5.8% following this news. AMIX's July 23 patent announcement was followed by -12.06% over 24 hours. The current patent similarly expanded intellectual-property coverage, but the platform record showed that favorable corporate updates had not aligned with historical trading outcomes.

Key Figures

U.S. Patent Number: 12,433,670 Patent Issuance Date: Aug. 04, 2026
2 metrics
U.S. Patent Number 12,433,670 Issued Aug. 04, 2026
Patent Issuance Date Aug. 04, 2026 U.S. patent issuance

Historical Context

5 past events · Latest: Jul 24 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jul 24 Preclinical study Positive -16.6% Preclinical renal nerve sensing results showed detectable signals and post-ablation attenuation.
Jul 23 U.S. patent grant Positive -12.1% Patent issuance expanded protection for autonomic nervous system assessment and precision neuromodulation technologies.
Jul 15 Bladder platform patent Positive -1.2% Patent covered catheter-based bladder nerve mapping and targeted therapeutic delivery methods.
Jul 13 Warrant inducement Negative -9.7% Warrant inducement offered immediate exercise terms and new Series D warrants.
Jul 13 Canadian patent grant Positive -12.5% Canadian patent grant broadened global protection for minimally invasive nerve-targeted therapies.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent positive or expansion-oriented announcements were followed by negative 24-hour reactions in all five selected historical events.

Key Terms

electrophysiological activity, autonomic nervous system, neuromodulation, neural mapping
4 terms
electrophysiological activity medical
"sense and map electrophysiological activity in nerves associated with tumors"
Electrophysiological activity is the electrical signaling produced by cells and tissues—most commonly nerves, the heart, or the brain—that shows how well they are working. Investors care because changes in these signals are used to diagnose conditions, measure whether a drug or device is helping or harming, and support regulatory approval; think of it as the electrical readout doctors use like a car’s dashboard to judge performance and safety.
autonomic nervous system medical
"broader organ-function applications and other autonomic nervous system disorders"
A network of nerves that automatically controls involuntary body functions such as heart rate, blood pressure, digestion and breathing, operating without conscious effort. Like an automatic thermostat that keeps a building’s climate steady, it is a major clinical target: drugs, devices or tests that affect this system can change patient outcomes, regulatory approval prospects and commercial value, so investors watch developments closely.
neuromodulation medical
"precision neuromodulation platform"
Neuromodulation is the use of devices or targeted treatments to change how nerves or brain circuits send signals, much like adjusting the volume or tuning on an audio system to alter what you hear. For investors, it matters because these therapies can treat chronic conditions (pain, movement disorders, depression) where existing medicines fall short, creating potential markets, regulatory milestones, and durable revenue streams if technologies prove safe and effective.
neural mapping technical
"Use neural mapping information to identify and guide treatment"
Mapping of how neurons or artificial neural units are organized and how they communicate, using measurements, images, or computational models to reveal circuits, activity patterns, and functional roles. Think of it like drawing a detailed road map of a brain or an AI system so engineers and scientists can see which routes carry information. For investors, neural mapping matters because it underpins the development, testing, and regulatory review of medical devices, drugs, and AI products that rely on understanding neural structure or behavior.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Patent expands protection for technology designed to sense, map and selectively target nerves associated with tumors and cancer-related pain

Strengthens Autonomix’s platform opportunity across oncology, autonomic nervous system disorders and broader organ-function applications

THE WOODLANDS, TX, Aug. 04, 2026 (GLOBE NEWSWIRE) -- Autonomix Medical, Inc. (NASDAQ: AMIX) (“Autonomix” or the “Company”), a medical device company dedicated to advancing precision nerve-targeted treatments, today announced the issuance of U.S. Patent No. 12,433,670, titled “Systems and Methods for Treating Cancer and/or Augmenting Organ Function.” The patent expands the Company’s intellectual property protection for technologies designed to sense, map and selectively target nerves associated with tumors, cancer-related pain, organ function and other autonomic nervous system disorders.

The patent covers minimally invasive systems designed to sense and map electrophysiological activity in nerves associated with tumors or metastatic cells and use that information to guide targeted treatment. The technology includes catheter-based microsurgical tools designed to record neural signals and deliver energy or therapeutic agents to selectively block or modulate identified nerves.

The patent describes technologies intended to:

  • Sense and map electrophysiological activity associated with tumors or metastatic cells;
  • Use neural mapping information to identify and guide treatment of targeted nerves;
  • Selectively block or modulate tumor-associated nerves to address cancer-related pain;
  • Deliver therapeutic energy or agents through minimally invasive catheter-based systems;
  • Target neural pathways that may influence tumors and the surrounding tumor microenvironment; and
  • Modulate autonomic nervous system signaling associated with organ function.

The patent also describes potential applications across a range of solid tumors, including pancreatic, prostate, breast, colorectal, liver, ovarian and bone cancers.

“This patent represents another meaningful expansion of our intellectual property portfolio and further demonstrates the breadth of our proprietary technology platform,” said Brad Hauser, Chief Executive Officer of Autonomix Medical. “Our strategy is to build a comprehensive intellectual property portfolio spanning precision nerve sensing, physiologic assessment and targeted neuromodulation, with potential applications across cancer, organ function and other diseases involving the autonomic nervous system. This latest patent strengthens the foundation supporting that strategy while reinforcing the versatility and long-term potential of our platform.”

The newly issued patent builds upon Autonomix's expanding intellectual property portfolio, which includes previously issued patents covering autonomic nervous system assessment, neural sensing, treatment guidance and transvascular neuromodulation technologies. Together, these patents support the Company's strategy of developing differentiated technologies designed to precisely identify and target disease-associated nerves across multiple therapeutic applications.

Autonomix continues to advance its proprietary technology platform designed to detect and differentiate neural signals with significantly greater sensitivity than conventional technologies, supporting the development of precision nerve-targeted therapies intended to improve patient outcomes while minimizing unintended effects on surrounding tissue.

About Autonomix Medical, Inc. 

Autonomix is a medical device company focused on advancing innovative technologies to revolutionize how diseases involving the nervous system are diagnosed and treated. The Company’s first-in-class platform system technology includes a catheter-based microchip sensing array that may have the ability to detect and differentiate neural signals with greater sensitivity than currently available technologies. We believe this will enable, for the first time ever, transvascular diagnosis and treatment of diseases involving the peripheral nervous system virtually anywhere in the body. 

We are initially developing this technology for the treatment of pain, with initial trials focused on pancreatic cancer, a condition that causes debilitating pain and is without a reliable solution. Our technology constitutes a platform to address dozens of potential indications, including cardiology, hypertension and chronic pain management, across a wide disease spectrum. Our technology is investigational and has not yet been cleared for marketing in the United States. 
 
For more information, visit autonomix.com and connect with the Company on XLinkedInInstagram and Facebook.
 
Forward Looking Statements 

Some of the statements in this release are “forward-looking statements,” which involve risks and uncertainties. Such forward-looking statements can be identified by the use of words such as “should,” “might,” “may,” “intends,” “anticipates,” “believes,” “estimates,” “projects,” “forecasts,” “expects,” “plans,” and “proposes.” Forward-looking statements in this press release include, but are not limited to, expectations regarding the scope and strategic value of the Company’s intellectual property portfolio, the potential effectiveness and clinical benefits of Autonomix’s nerve-targeted treatments, including for cancer-related pain and pancreatic cancer pain, the capabilities and potential clinical utility of the Company’s neural sensing platform technology, the ability of the platform to detect, localize and confirm changes in neural activity, the potential role of neural sensing in guiding targeted neuromodulation procedures, and the potential applicability of the technology across multiple indications.

Although Autonomix believes that the expectations reflected in these forward-looking statements are based on reasonable assumptions, there are a number of risks and uncertainties that could cause actual results to differ materially from such forward-looking statements. You are urged to carefully review and consider any cautionary statements and other disclosures, including the statements made under the heading “Risk Factors” and elsewhere in the Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (SEC) on May 27, 2026, and from time to time, our other filings with the SEC. Forward-looking statements speak only as of the date of this press release and Autonomix does not undertake any duty to update any forward-looking statements except as may be required by law.

Investor and Media Contact 

JTC Team, LLC 
Jenene Thomas
908.824.0775
autonomix@jtcir.com


FAQ

What did Autonomix Medical (NASDAQ: AMIX) announce on August 4, 2026?

Autonomix Medical announced issuance of U.S. Patent No. 12,433,670 covering its precision neuromodulation technologies. According to Autonomix Medical, the patent expands protection for systems that sense, map and selectively target nerves related to tumors, cancer pain, organ function and autonomic nervous system disorders.

How does the new U.S. patent support Autonomix Medical’s AMIX neuromodulation platform?

The new patent broadens intellectual property protection around Autonomix Medical’s precision nerve sensing and targeting platform. According to Autonomix Medical, it covers minimally invasive catheter-based systems that record neural signals and deliver energy or agents to modulate disease-associated nerves across multiple therapeutic applications.

Which cancer types are potential targets under Autonomix Medical’s new patent for AMIX?

The patent describes potential applications across several solid tumors, including pancreatic, prostate, breast, colorectal, liver, ovarian and bone cancers. According to Autonomix Medical, the covered technologies aim to sense and map tumor-associated nerve activity and guide targeted neuromodulation or therapy delivery.

What specific technologies are covered by Autonomix Medical’s U.S. Patent No. 12,433,670?

The patent covers minimally invasive systems that sense and map electrophysiological nerve activity and guide targeted treatment. According to Autonomix Medical, it includes catheter-based microsurgical tools that record neural signals and deliver therapeutic energy or agents to selectively block or modulate identified nerves.

How does the new patent fit into Autonomix Medical’s broader IP portfolio and strategy for AMIX?

The patent adds to Autonomix Medical’s existing portfolio covering autonomic assessment, neural sensing, treatment guidance and transvascular neuromodulation. According to Autonomix Medical, these patents collectively support a strategy to develop differentiated technologies for precisely identifying and targeting disease-associated nerves across multiple conditions.

What clinical applications does Autonomix Medical foresee for its newly patented nerve-targeting technology?

The patent outlines potential uses in treating cancer-related pain, influencing tumor-associated neural pathways and modulating organ-related autonomic signaling. According to Autonomix Medical, the technologies are intended for minimally invasive, catheter-based delivery to support precision nerve-targeted therapies while limiting effects on surrounding tissue.