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Semler Scientific® Reports Second Quarter 2025 Financial Results, BTC Holdings of 5,021 and BTC Yield of 31.3% YTD through July 31, 2025

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Semler Scientific (NASDAQ:SMLR) reported Q2 2025 financial results and significant Bitcoin holdings. The company held 5,021 Bitcoins valued at $586.2 million as of July 31, 2025, achieving a 31.3% BTC yield YTD with unrealized gains of $110.4 million.

Q2 2025 financial highlights include revenues of $8.2 million (43% decrease YoY), net income of $66.9 million ($5.71 per basic share), and pre-tax income of $80.6 million. The company launched CardioVanta™, a subsidiary focused on heart failure detection, and raised approximately $194.3 million through an ATM offering.

[ "Bitcoin holdings generated $110.4 million in unrealized gains YTD", "Strong BTC yield of 31.3% YTD through July 31, 2025", "Net income increased to $66.9 million in Q2 2025 from $11,000 in Q2 2024", "Successfully raised $194.3 million through ATM offering", "Launched CardioVanta subsidiary for healthcare expansion" ]

Semler Scientific (NASDAQ:SMLR) ha riportato i risultati finanziari del secondo trimestre 2025 e importanti partecipazioni in Bitcoin. Al 31 luglio 2025, la società deteneva 5.021 Bitcoin valutati 586,2 milioni di dollari, con un rendimento BTC del 31,3% da inizio anno e guadagni non realizzati pari a 110,4 milioni di dollari.

I principali dati finanziari del Q2 2025 includono ricavi per 8,2 milioni di dollari (in calo del 43% rispetto all'anno precedente), un utile netto di 66,9 milioni di dollari (5,71 dollari per azione base) e un reddito ante imposte di 80,6 milioni di dollari. L'azienda ha lanciato CardioVanta™, una controllata focalizzata sulla rilevazione dell'insufficienza cardiaca, e ha raccolto circa 194,3 milioni di dollari tramite un'offerta ATM.

Semler Scientific (NASDAQ:SMLR) informó los resultados financieros del segundo trimestre de 2025 y una significativa tenencia de Bitcoin. La compañía poseía 5,021 Bitcoins valorados en 586,2 millones de dólares al 31 de julio de 2025, logrando un rendimiento BTC del 31,3% en lo que va del año con ganancias no realizadas de 110,4 millones de dólares.

Los aspectos destacados financieros del Q2 2025 incluyen ingresos de 8,2 millones de dólares (una disminución del 43% interanual), un ingreso neto de 66,9 millones de dólares (5,71 dólares por acción básica) y un ingreso antes de impuestos de 80,6 millones de dólares. La empresa lanzó CardioVanta™, una subsidiaria enfocada en la detección de insuficiencia cardíaca, y recaudó aproximadamente 194,3 millones de dólares a través de una oferta ATM.

Semler Scientific (NASDAQ:SMLR)은 2025년 2분기 재무 실적과 상당한 비트코인 보유량을 보고했습니다. 2025년 7월 31일 기준으로 회사는 5,021 비트코인, 가치 5억 8,620만 달러를 보유하고 있으며, 연초 대비 31.3% BTC 수익률과 1억 1,040만 달러의 미실현 이익을 기록했습니다.

2025년 2분기 주요 재무 하이라이트는 매출 820만 달러(전년 대비 43% 감소), 순이익 6690만 달러(기본 주당 5.71달러), 세전 이익 8,060만 달러입니다. 회사는 심부전 탐지에 중점을 둔 자회사 CardioVanta™를 출범시키고 ATM 공모를 통해 약 1억 9,430만 달러를 조달했습니다.

Semler Scientific (NASDAQ:SMLR) a publié ses résultats financiers du deuxième trimestre 2025 ainsi que ses importantes détentions en Bitcoin. Au 31 juillet 2025, la société détenait 5 021 Bitcoins d'une valeur de 586,2 millions de dollars, réalisant un rendement BTC de 31,3 % depuis le début de l'année avec des gains non réalisés de 110,4 millions de dollars.

Les points forts financiers du T2 2025 incluent des revenus de 8,2 millions de dollars (en baisse de 43 % en glissement annuel), un bénéfice net de 66,9 millions de dollars (5,71 dollars par action de base) et un résultat avant impôts de 80,6 millions de dollars. L'entreprise a lancé CardioVanta™, une filiale dédiée à la détection de l'insuffisance cardiaque, et a levé environ 194,3 millions de dollars via une offre ATM.

Semler Scientific (NASDAQ:SMLR) meldete die Finanzergebnisse für das zweite Quartal 2025 sowie bedeutende Bitcoin-Bestände. Das Unternehmen hielt zum 31. Juli 2025 5.021 Bitcoins im Wert von 586,2 Millionen US-Dollar und erzielte eine BTC-Rendite von 31,3 % seit Jahresbeginn mit unrealisierte Gewinnen von 110,4 Millionen US-Dollar.

Die wichtigsten finanziellen Eckdaten im Q2 2025 umfassen Umsätze von 8,2 Millionen US-Dollar (Rückgang um 43 % gegenüber dem Vorjahr), einen Nettogewinn von 66,9 Millionen US-Dollar (5,71 US-Dollar je Stammaktie) sowie ein Vorsteuerergebnis von 80,6 Millionen US-Dollar. Das Unternehmen brachte CardioVanta™ auf den Markt, eine Tochtergesellschaft, die sich auf die Erkennung von Herzinsuffizienz spezialisiert hat, und sammelte rund 194,3 Millionen US-Dollar durch ein ATM-Angebot ein.

Positive
  • None.
Negative
  • Revenue declined 43% year-over-year to $8.2 million
  • Operating loss of $2.1 million compared to $5.4 million income in Q2 2024
  • High customer concentration with two clients representing 76% of revenue
  • $29.75 million litigation contingency for DOJ settlement
  • Operating expenses increased to $10.3 million from $9.1 million YoY

Insights

Semler transformed from healthcare to Bitcoin play with 5,021 BTC ($586.2M), showing 31.3% YTD yield despite 43% revenue decline.

Semler Scientific has undergone a dramatic strategic pivot, transforming from a medical device company to a corporate Bitcoin holder with $586.2 million in BTC assets (5,021 Bitcoin) as of July 31, 2025. The company's Bitcoin treasury strategy has generated $110.4 million in unrealized gains YTD, delivering a 31.3% yield through July.

However, this Bitcoin strategy coincides with significant deterioration in the core healthcare business. Q2 revenues plummeted 43% year-over-year to $8.2 million, resulting in an operating loss of $2.1 million compared to operating income of $5.4 million in Q2 2024. The healthcare revenue decline appears substantial and concerning.

Notably, Semler reported net income of $66.9 million ($5.71 per basic share), but this was driven by an $83.8 million unrealized gain from Bitcoin appreciation. Without this paper gain, the company would have shown a significant loss.

The balance sheet has transformed dramatically, with digital assets now comprising $496.9 million of the company's $522.6 million total assets. To fund Bitcoin purchases, Semler has raised capital through:

  • ATM equity offerings generating net proceeds of $320.3 million
  • Issuance of senior convertible notes raising $100 million

The company also faces a $29.8 million contingent liability related to a proposed settlement with the DOJ, adding further pressure on operations.

Semler's Bitcoin strategy represents an extraordinary pivot - they've essentially transformed into a publicly-traded Bitcoin investment vehicle with a declining healthcare business attached. This makes the stock primarily a leveraged bet on Bitcoin's performance rather than a healthcare technology investment.

CAMPBELL, Calif., Aug. 4, 2025 /PRNewswire/ -- Semler Scientific, Inc. (Nasdaq: SMLR), a publicly traded company that has adopted Bitcoin as its primary treasury reserve asset and is one of the leading corporate holders of Bitcoin, today reported financial results for the second quarter ended June 30, 2025 and provided an update on its Bitcoin holdings and other key performance indicators (KPIs).

"We have made excellent progress with our Bitcoin treasury strategy," said Eric Semler, executive chairman of Semler Scientific. "We purchased approximately $195.4 million of Bitcoin since the first quarter, bringing the value of our total holdings to nearly $586.2 million as of July 31, 2025. Year-to-date through July 31, 2025, this strategy has generated more than $110.4 million in unrealized gains and delivered a 31.3% BTC yield. We also deepened our connection to the Bitcoin community by appointing Natalie Brunell to our board of directors and hiring Joe Burnett as director of Bitcoin strategy." 

"During the quarter, we were very pleased to launch CardioVanta™, a wholly owned subsidiary that will drive our future healthcare initiatives focused on early detection of heart failure and cardiac arrhythmia," said Doug Murphy-Chutorian, MD, chief executive officer of Semler Scientific. "We believe CardioVanta positions us to deliver long-term value in our healthcare business as we continue to aggressively execute on our Bitcoin treasury strategy — establishing Semler Scientific as a dual-engine platform for growth." 

BITCOIN TREASURY HIGHLIGHTS AND OTHER RECENT DEVELOPMENTS

  • "BTC Yield" KPI: Achieved BTC Yield of 29.0% in Q2 and 31.3% year-to-date through July 31, 2025.
  • "BTC Gain" KPI: Achieved BTC Gain of 185 in Q2 and 719 year-to-date through July 31, 2025.
  • "BTC $ Gain" KPI: Achieved BTC $ Gain of $20.3 million in Q2 and $84.0 million year-to-date through July 31, 2025.
  • Digital Assets: As of June 30, 2025, Semler Scientific held 4,636 Bitcoins with a fair value of $496.9 million, which reflects a cumulative increase in fair value of $66.9 million. During the quarter ended June 30, 2025, Semler Scientific purchased 1,444 Bitcoins for an aggregate cost of $149.6 million. Subsequently through July 31, 2025, Semler Scientific purchased an additional 385 Bitcoins for an aggregate cost of $45.8 million. Semler Scientific's total holdings as of July 31, 2025 were 5,021 Bitcoins with a fair value of $586.2 million and an aggregate purchase amount of $475.8 million from operating cashflow, monetization of a minority investment, and proceeds from its at the market (ATM) and senior convertible notes offerings. All purchase amounts include fees and expenses. Fair value on July 31, 2025 is based on 4:00pm ET $116,758 price per Bitcoin as reported on Coinbase exchange.
  • At-the-Market Equity Offering Program: On April 15, 2025, Semler Scientific entered into a new Controlled Equity OfferingSM Sales Agreement (the new Sales Agreement) with Barclays Capital Inc., Cantor Fitzgerald & Co., Canaccord Genuity LLC, Needham & Company, LLC, Craig-Hallum Capital Group LLC and Lake Street Capital Markets, LLC pursuant to which it may issue and sell from time to time up to $500.0 million of its common stock in an ATM offering. The new Sales Agreement replaced the Controlled Equity OfferingSM Sales Agreement (the initial Sales Agreement) that Semler Scientific entered into with Cantor Fitzgerald & Co. in June 2024. As of July 31, 2025, Semler Scientific had sold an aggregate of 2,438,274 shares of its common stock under the initial Sales Agreement for aggregate net proceeds of approximately $126.0 million. As the registration statement and prospectus for the new Sales Agreement is now effective, Semler Scientific is no longer selling any shares under the initial Sales Agreement. From the time of effectiveness through July 31, 2025, Semler Scientific issued and sold 4,932,737 shares of its common stock for aggregate net proceeds of approximately $194.3 million under the new Sales Agreement.

Bitcoin Dashboard

Semler Scientific maintains a dashboard on its website, www.semlerscientific.com, as a disclosure channel to provide broad, non-exclusionary distribution of information regarding Semler Scientific's Bitcoin holdings to the public. Some of the information distributed through the website dashboard may be considered material information. Semler Scientific intends to use this website dashboard as a means of complying with its disclosure obligations under Regulation FD. The website dashboard will include information regarding market data for Semler Scientific's common stock and Bitcoin, BTC Yield, BTC Gain and BTC $ Gain KPIs, Bitcoin purchases, Bitcoin holdings, and other related information. Investors and others are encouraged to regularly review the information that Semler Scientific makes public via the website dashboard.

FINANCIAL RESULTS

For the second quarter ended June 30, 2025, Semler Scientific reported:

  • Revenues of $8.2 million, a 43% decrease year-over-year.
  • Total operating expenses, which include cost of revenues, of $10.3 million, compared to $9.1 million for the second quarter of 2024. Operating expenses include $1.9 million in non-cash stock-based compensation and $0.5 million of legal expenses of related to the proposed settlement agreement with the U.S. Department of Justice (DOJ) pertaining to a civil investigative demand.
  • Loss from operations of $2.1 million, compared to income from operations of $5.4 million for the second quarter of 2024.
  • Pre-tax income of $80.6 million, compared to $1.1 million for the second quarter of 2024. Second quarter 2025 and 2024 pre-tax income includes an unrealized gain and unrealized loss from the change in fair value of Semler Scientific's Bitcoin holdings of $83.8 million and $5.1 million, respectively.
  • Income tax expense of $13.6 million, or an effective tax rate of 17%, compared to expense of $1.1 million, or an effective tax rate of 99% for the second quarter of 2024.
  • Net income of $66.9 million, or $5.71 per basic and $5.04 diluted share, compared to net income of $11 thousand, or $0.0 per basic share and diluted share for the second quarter of 2024.

Semler Scientific's two largest customers (including their affiliates) comprised 45% and 31% of second quarter revenues in 2025, respectively, and its three largest customers comprised 44%, 27% and 11% of second quarter 2024 revenues, respectively.

Notice of Conference Call

Semler Scientific will host a live video webinar today at 4:30 p.m. ET. The webinar will address the results of the Second quarter ended June 30, 2025, as well as provide a business update on Semler Scientific's strategies for the near-term future. Questions can be submitted prior to the start of the call to ir@semlerscientific.com.

A live video webinar of the event can be accessed at: https://event.choruscall.com/mediaframe/webcast.html?webcastid=GSe0xNiE. The live video webinar will also be live streamed on The Bitcoin for Corporations YouTube page at https://www.youtube.com/@BitcoinforCorporations.

Those without internet access may dial in by calling one of the following numbers and specify to the operator that you would like to join the "Semler Scientific Call":
Domestic callers: 833-816-1161
International callers: 412-317-0717

The video webinar will be archived for one year on Semler Scientific's website at www.semlerscientific.com.

 

Semler Scientific, Inc.

Condensed Consolidated Statements of Operations

Unaudited

(In thousands of U.S. Dollars, except share and per share data)




For the three months ended June 30, 


For the six months ended June 30, 




2025


2024


2025


2024

Revenues


$

8,217


$

14,465


$

17,052


$

30,368

Operating expenses:













Cost of revenues



739



1,255



1,677



2,501

Engineering and product development



1,237



1,440



2,552



2,578

Sales and marketing



3,154



3,456



6,195



7,131

General and administrative



5,140



2,964



10,034



5,832

Litigation contingency







29,750



Total operating expenses



10,270



9,115



50,208



18,042

(Loss) income from operations



(2,053)



5,350



(33,156)



12,326

Interest (expense) income, net



(1,145)



714



(1,948)



1,534

Impairment of investments







(1,135)



Change in fair value of notes held for investment





128





128

Change in fair value of intangible digital assets



83,761



(5,055)



41,932



(5,055)

Other income (expense), net



82,616



(4,213)



38,849



(3,393)

Pre-tax income



80,563



1,137



5,693



8,933

Income tax provision



13,630



1,126



3,463



2,849

Net income


$

66,933


$

11


$

2,230


$

6,084

Net income per share, basic


$

5.71


$

0.00


$

0.21


$

0.88

Weighted average number of shares used in computing basic net income per share



11,727,660



6,944,664



10,661,851



6,918,709

Net income per share, diluted


$

5.04


$

0.00


$

0.25


$

0.78

Weighted average number of shares used in computing diluted net income per share



13,484,746



7,795,149



12,260,223



7,789,101

 

Semler Scientific, Inc.

Condensed Consolidated Balance Sheets

(In thousands of U.S. Dollars, except share and per share data)




June 30, 


December 31, 



2025


2024




Unaudited




Assets







Current Assets:







Cash and cash equivalents


$

13,482


$

8,819

Restricted cash



134



133

Short-term notes receivable





6,100

Short-term deposits



270



Trade accounts receivable, net of allowance for credit losses of $98 and $199

respectively



2,831



4,378

Inventory



558



358

Prepaid expenses and other current assets



4,623



2,900

Total current assets



21,898



22,688

Assets for lease, net



1,431



1,423

Property and equipment, net



368



487

Long-term investments



512



512

Long-term notes receivable



1,500



Intangible digital assets



496,865



214,633

Other non-current assets



23



85

Total assets


$

522,597


$

239,828








Liabilities and Stockholders' Equity







 Current liabilities:







Accounts payable


$

156


$

140

Accrued expenses



6,013



5,173

Accrued contingent liability



29,750



Deferred revenue



638



774

Other short-term liabilities



215



226

Total current liabilities



36,772



6,313








Long-term liabilities:







Deferred tax liability



6,161



2,765

Long-term notes payable, net



96,255



Total long-term liabilities



102,416



2,765

Commitments and contingencies







Stockholders' equity:







Common stock, $0.001 par value; 50,000,000 shares authorized; 13,902,827 and

9,770,908 shares issued, and 13,688,405 and 9,556,486 shares outstanding (treasury

shares of 214,422 and 214,422), respectively



14



9

Additional paid-in capital



280,463



130,039

Retained earnings



102,932



100,702

Total stockholders' equity



383,409



230,750








Total liabilities and stockholders' equity


$

522,597


$

239,828

 

Semler Scientific, Inc.

Condensed Consolidated Statements of Cash Flows

Unaudited

(In thousands of U.S. Dollars)




For the six months ended June 30, 



2025


2024

CASH FLOWS FROM OPERATING ACTIVITIES:







Net income


$

2,230


$

6,084








Reconciliation of Net Income to Net Cash (Used in) Provided by Operating Activities:







Depreciation



229



346

Amortization of debt issuance costs



272



Deferred tax benefit (expense)



3,396



(163)

Loss on disposal of assets for lease



160



319

Allowance for credit losses



(101)



(44)

Change in fair value of notes held for investment





(128)

Change in fair value of digital assets



(41,932)



5,055

Stock-based compensation



3,378



295

Impairment of investments



1,135



Changes in Operating Assets and Liabilities:







Trade accounts receivable



1,648



(1,292)

Inventory



(200)



60

Prepaid expenses and other current assets



(1,993)



(135)

Other non-current assets



62



43

Accounts payable



16



(175)

Accrued expenses



30,491



584

Other current and non-current liabilities



(47)



(11)

Deferred revenue



(136)



(280)

Net Cash (Used in) Provided by Operating Activities



(1,392)



10,558








CASH FLOWS FROM INVESTING ACTIVITIES:







Additions to property and equipment





(48)

Purchase of notes held for investment





(500)

Purchase of digital assets



(240,300)



(60,000)

Proceeds from maturities of notes receivable



3,600



Purchase of assets for lease



(278)



Net Cash Used in Investing Activities



(236,978)



(60,548)








CASH FLOWS FROM FINANCING ACTIVITIES:







Taxes paid related to net settlement of equity awards





(45)

Proceeds from issuance of debt



100,000



Debt issuance costs



(4,017)



Capital call premium



(7,740)



Proceeds from issuance of common stock



156,923



Stock issuance expenses



(2,690)



(102)

Proceeds from exercise of stock options



558



269

Net Cash Provided by Financing Activities



243,034



122

NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS



4,664



(49,868)

CASH, CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD



8,952



57,332

CASH, CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD


$

13,616


$

7,464

 

Digital Assets- Additional Information

Rollforward of Bitcoin holdings

Unaudited

(in thousands of U.S. Dollars, except Bitcoin held and price per Bitcoin)



Source of   












Approximate 


Capital













Average


Used to













Purchase


Purchase


Digital Assets


Change in


Digital Assets

Approximate 


Price Per


Bitcoin


at Cost


Fair Value


at Fair Value

Bitcoin Held


Bitcoin (in $)

Balance as of December 31, 2023



$


$


$



$

Digital assets purchased











Balance as of March 31, 2024











Digital assets purchased

(a)



60,000





60,000


877



68,436

Change in fair value of the digital assets






(5,055)



(5,055)




Balance as of June 30, 2024



$

60,000


$

(5,055)


$

54,945


877


$

68,436

Digital assets purchased

(b)



8,400





8,400


141



59,372

Change in fair value of the digital assets






1,137



1,137




Balance as of September 30, 2024



$

68,400


$

(3,918)


$

64,482


1,018


$

67,177

Digital assets purchased

(b)



121,300





121,300


1,280



94,755

Change in fair value of the digital assets






28,851



28,851




Balance as of December 31, 2024



$

189,700


$

24,933


$

214,633


2,298


$

82,538

Digital assets purchased

(c)



90,700





90,700


894



101,531

Change in fair value of the digital assets






(41,829)



(41,829)




Balance as of March 31, 2025



$

280,400


$

(16,896)


$

263,504


3,192


$

87,854

Digital assets purchased

(b)



149,600





149,600


1,444



103,581

Change in fair value of the digital assets






83,761



83,761




Balance as of June 30, 2025



$

430,000


$

66,865


$

496,865


4,636


$

92,753

 



(a)

Cash from operations.

(b)

Cash from operations and proceeds from ATM offering.

(c)

Proceeds from 4.25% senior convertible notes.

 

Bitcoin Yield Key Performance Indicators

Unaudited

(In thousands)



12/31/2024


3/31/2025


6/30/2025 (2)


7/31/2025

Total Bitcoin holdings

2,298


3,192


4,636


5,021

Shares outstanding








Basic shares outstanding

9,556


9,596


13,788


14,805

Stock options outstanding

692


1,140


1,303


1,311

2030 senior notes


935


935


935

Assumed diluted shares outstanding (1)

10,248


11,671


16,026


17,051

BTC Yield % QTD



21.9 %


5.80 %


1.8 %

BTC Yield % YTD



21.9 %


29.0 %


31.3 %



(1)

Assumed Diluted Shares Outstanding refers to the aggregate of Semler Scientific's Basic Shares outstanding as of the end of each period plus all the additional shares that would result from the assumed conversion of all outstanding convertible notes and related capped calls, and exercise of all outstanding stock option awards. Assumed Diluted Shares Outstanding is not calculated using the treasury method and does not take into account any vesting conditions (in the case of equity awards), the exercise price of any stock option awards or any contractual conditions limiting convertibility of outstanding convertible notes or settlement of capped calls.

(2)

Basic shares outstanding as of 6/30/2025 includes 100 shares sold through the ATM on 6/30/2025 and settled on 7/1/2025

 

Semler Scientific, Inc.

Reconciliation of GAAP to Non-GAAP measures

Unaudited

(in thousands)




Three months ended June 30, 



Six months ended June 30



2025


2024


2025


2024



(Unaudited)


(Unaudited)


(Unaudited)


(Unaudited)














Reconciliation of non-GAAP (loss) income from operations:













(Loss) income from operations


$

(2,053)


$

5,350


$

(33,156)


$

12,326

Contingent liability







29,750



Stock-based compensation expense



1,895



268



3,378



295

Non-GAAP (loss) income from operations


$

(158)


$

5,618


$

(28)


$

12,621

Important Information about BTC Yield, BTC Gain and BTC $ Gain (KPIs)

BTC Yield, BTC Gain and BTC $ Gain are KPIs that Semler Scientific uses to help assess the performance of its strategy of acquiring Bitcoin in a manner it believes is accretive to stockholders.

BTC Yield is a KPI that represents the percentage change period-to-period of the ratio between Semler Scientific's Bitcoin holdings and its Assumed Diluted Shares Outstanding. Assumed Diluted Shares Outstanding refers to the aggregate of Semler Scientific's actual shares of common stock outstanding as of the end of each period plus all additional shares that would result from the assumed exercise of all outstanding stock option awards. Assumed Diluted Shares Outstanding is not calculated using the treasury method and does not take into account any vesting conditions or the exercise price of any stock option awards.

BTC Gain is a KPI that represents the number of Bitcoins held by Semler Scientific at the beginning of a period multiplied by the BTC Yield for such period.

BTC $ Gain is a KPI that represents the dollar value of the BTC Gain calculated by multiplying the BTC Gain by the market price of Bitcoin as of 4:00 p.m. ET on the Coinbase exchange on the last day of the applicable period. Semler Scientific has elected 4:00 p.m. ET on the last day of the applicable period as the date and time of determination of the market price of Bitcoin solely for the purpose of facilitating this illustrative calculation.

Non-GAAP Financial Measure:

Semler Scientific prepares its condensed consolidated financial statements in conformity with accounting principles generally accepted in the United States of America (GAAP) and pursuant to accounting requirements of the Securities and Exchange Commission (SEC). In an effort to provide investors with additional information regarding the results and to provide a meaningful period-over-period comparison of Semler Scientific's financial performance, Semler Scientific sometimes uses non-U.S. GAAP financial measures (NGFMs) as defined by the SEC. In this press release, Semler Scientific is providing a supplemental NGFM, non-GAAP (loss) income from operations, which NGFM excludes (i) non-cash stock-based compensation expense, and (ii) the DOJ contingent liability, which is a non-recurring item.

Semler Scientific believes this NGFM measure is useful to investors and analysts in comparing its performance across reporting periods on a consistent basis as it excludes a significant non-cash expense and a non-recurring item that Semler Scientific believes are not reflective of its general business performance. Accounting for stock-based compensation expense requires management judgment, and the resulting stock-based compensation expense could vary significantly in comparison to other companies. The DOJ investigation and resulting contingent liability is non-recurring in nature. Semler Scientific used this NGFM to evaluate Semler Scientific's financial performance against internal budgets and targets. Semler Scientific believes the use of this NGFM can also facilitate comparison of Semler Scientific's operating results to those of its competitors. Semler Scientific believes this NGFM should be considered in addition to, and not in lieu of, GAAP financial measures. Semler Scientific's NGFM may be different from the same NGFM used by other companies.

About Semler Scientific, Inc.:

Semler Scientific, Inc. is the second U.S. public company to adopt Bitcoin as its primary treasury reserve asset and is a leader in medical devices and software to combat chronic diseases. By using proceeds from equity and debt financings, as well as cash flows from operations, Semler Scientific intends to strategically accumulate Bitcoin. In addition, through its healthcare businesses, Semler Scientific and its wholly-owned subsidiary, CardioVanta, Inc. develop and market products and services for early detection and monitoring of chronic diseases. Semler Scientific's flagship product, QuantaFlo, which is patented and cleared by the U.S. Food and Drug Administration (FDA), provides rapid point-of-care testing to measure arterial blood flow in the extremities. The QuantaFlo test aids in the diagnosis of peripheral arterial disease. Additional information about Semler Scientific can be found at www.semlerscientific.com.

Semler Scientific intends to use its Bitcoin dashboard and its Investor Relations website as a means of disclosing material nonpublic information and for complying with its disclosure obligations under Regulation FD. Accordingly, investors should monitor Semler Scientific's Bitcoin dashboard and Investor Relations website, in addition to following Semler Scientific's press releases, SEC filings, public conference calls, presentations, and webcasts.

Forward-Looking Statements

This press release contains "forward-looking" statements. Such statements can be identified by, among other things, the use of forward-looking language such as the words "believe," "goal," "may," "will," "intend," "expect," "anticipate," "estimate," "project," "would," "could" or words with similar meaning or the negatives of these terms or by the discussion of strategy or intentions. The forward-looking statements in this release include express or implied statements regarding acquiring and holding Bitcoin; sales of securities under the ATM offering program and other financings to support additional Bitcoin purchases; the strategy for, and innovation and growth in, its healthcare business, including growth and cash generation from FDA-cleared products and CardioVanta; seeking a new 510(k) clearance for QuantaFlo with expanded indications; and potential DOJ settlement; among others. Such forward-looking statements are subject to a number of risks and uncertainties that could cause Semler Scientific's actual results to differ materially from those discussed here, such as risks inherent with investing in Bitcoin, including Bitcoin's volatility; risk of implementing a Bitcoin treasury strategy; risk that insurance plans and other customers will not continue to license its cardiovascular testing products or license new FDA-cleared products and services; risk of changes in the reimbursement landscape for its customers including related to the Centers for Medicare and Medicaid Services (CMS) rate announcement; risk of obtaining a new 510(k) clearance for expanded indications; conducting its healthcare business through CardioVanta; risks related to reaching a final settlement with DOJ, including risk that DOJ will file complaint seeking in excess of the agreed amount if unable to agree on final settlement terms; risks related to Semler Scientific's indebtedness; along with those other risk factors detailed in Semler Scientific's filings with the SEC. These forward-looking statements involve assumptions, estimates, and uncertainties that reflect current internal projections, expectations or beliefs. There can be no assurance that such statements will prove to be accurate, and actual results and future events could differ materially from those anticipated in such statements. All forward-looking statements contained in this press release are qualified in their entirety by these cautionary statements and the risk factors described above. Furthermore, all such statements are made as of the date of this press release and Semler Scientific assumes no obligation to update or revise these statements unless otherwise required by law.

No Offer or Solicitation

This press release does not and shall not constitute an offer to sell or a solicitation of an offer to buy any securities of Semler Scientific, Inc., nor shall there be any offer, solicitation or sale of such securities, in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

INVESTOR CONTACT:

Renae Cormier
Chief Financial Officer
ir@semlerscientific.com

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SOURCE Semler Scientific, Inc.

FAQ

What is Semler Scientific's (SMLR) Bitcoin holdings value as of July 2025?

Semler Scientific held 5,021 Bitcoins valued at $586.2 million as of July 31, 2025, with an aggregate purchase amount of $475.8 million.

How did SMLR perform financially in Q2 2025?

SMLR reported Q2 2025 revenues of $8.2 million (43% decrease YoY), net income of $66.9 million, and pre-tax income of $80.6 million, including $83.8 million in unrealized Bitcoin gains.

What was Semler Scientific's Bitcoin yield in 2025?

SMLR achieved a BTC yield of 29.0% in Q2 and 31.3% year-to-date through July 31, 2025, generating over $110.4 million in unrealized gains.

How much did SMLR raise through its ATM offering?

Through July 31, 2025, SMLR raised $194.3 million by selling 4,932,737 shares under the new Sales Agreement, plus $126.0 million from the initial agreement.

What are the major challenges facing SMLR in 2025?

Key challenges include a 43% revenue decline, operating losses of $2.1 million, high customer concentration with two clients representing 76% of revenue, and a $29.75 million DOJ settlement contingency.
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