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#1 NKTX leads with +61% April 2022

NKTX (Nkarta, Inc.) is the best performing stock in April 2022. Following are RCMT (+60%) and DDL (+45%). Top performing sectors: Real Estate (+33% avg, 1 in top 10), Healthcare (+26% avg, 3 in top 10), Industrials (+23% avg, 3 in top 10).

Top Stock Gainers April 2022 - Monthly Performance Ranked

Track the top performing stocks of April 2022 ranked by monthly price gain. See which stock gainers delivered the highest gains this month, with market caps over $100 million on Nasdaq and NYSE.
2022

This ranking shows the top performing stocks and biggest stock gainers during April 2022, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

April 2022 Stock Market Momentum

This page answers a current-month trend question with data: which NYSE and NASDAQ stocks have shown the strongest price gains so far in April 2022. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?

Data as of April 27, 2026 at 3:27 AM EDT

Rank
Symbol
Company Name
Apr Gain
Market Cap
Price
Country
Sector
1
61.19%
208.17 M
$ 2.92
United States
Healthcare
2
59.63%
234.32 M
$ 31.62
United States
Industrials
3
45.48%
559.27 M
$ 2.58
China
Consumer Defensive
4
42.17%
246.69 M
$ 3.22
Singapore
Technology
5
42.11%
2.05 B
$ 14.41
United States
Healthcare
6
35.73%
683.85 M
$ 16.76
Bermuda
Industrials
7
35.33%
235.78 M
$ 8.9
United States
Healthcare
8
33.05%
234.20 M
$ 14.5
United States
Real Estate
9
32.1%
1.64 B
$ 41.18
United States
Basic Materials
10
27.73%
260.76 M
$ 32.1
United States
Industrials
11
25%
130.43 M
$ 3.57
United States
Technology
12
23.48%
752.67 M
$ 15.97
United States
Energy
13
22.7%
6.74 B
$ 11.95
United States
Technology
14
22.54%
225.24 M
$ 5.24
United States
Energy
15
21.73%
4.98 B
$ 16.94
United States
Energy
16
21.45%
809.96 M
$ 22.1
United States
Technology
17
20.81%
102.03 M
$ 2.88
United States
Energy
18
20.53%
172.70 M
$ 0.421
United States
Financial Services
19
20.2%
240.51 M
$ 9.71
United States
Technology
20
20.04%
787.21 M
$ 6.23
United States
Energy
21
19.74%
1.76 B
$ 3.7
United States
Technology
22
19.21%
2.88 B
$ 50.39
United States
Consumer Defensive
23
18%
195.76 M
$ 4.2
United States
Energy
24
17.46%
4.79 B
$ 40.74
United States
Energy
25
17.43%
1.17 B
$ 5.54
Bermuda
Energy
26
17.41%
456.85 M
$ 13.54
United States
Consumer Cyclical
27
17.27%
6.97 B
$ 203.07
United States
Consumer Cyclical
28
17.16%
234.64 M
$ 14.63
United States
Basic Materials
29
17.03%
480.32 M
$ 18.5
United States
Consumer Cyclical
30
16.91%
102.26 M
$ 3.05
United States
Healthcare
31
16.64%
3.01 B
$ 14.19
United States
Energy
32
16.41%
118.74 M
$ 2.78
United States
Industrials
33
16.38%
3.92 B
$ 203.06
United States
Consumer Cyclical
34
16.22%
3.20 B
$ 24.9
United States
Energy
35
16.17%
9.83 B
$ 531.29
United States
Consumer Cyclical
36
16.06%
3.38 B
$ 4.58
Canada
Energy
37
15.57%
241.12 M
$ 5.84
United States
Energy
38
15.37%
1.95 B
$ 35.49
United States
Consumer Defensive
39
15.19%
5.22 B
$ 153.46
Hong Kong
Technology
40
14.76%
2.40 B
$ 187.23
United States
Basic Materials
41
14.62%
192.33 M
$ 15.9
United States
Financial Services
42
14.52%
491.64 M
$ 1.91
United States
Healthcare
43
14.37%
490.50 M
$ 25.24
United States
Industrials
44
14.04%
258.14 M
$ 48.2
United States
Consumer Cyclical
45
14.04%
9.67 B
$ 219
United States
Financial Services
46
13.96%
3.95 B
$ 78.37
Monaco
Energy
47
13.79%
5.49 B
$ 84.33
United States
Healthcare
48
13.75%
1.25 B
$ 5.02
United States
Technology
49
13.54%
6.59 B
$ 107.74
United States
Consumer Cyclical
50
13.5%
183.31 M
$ 6.06
United States
Energy
51
13.47%
1.91 B
$ 12.665
United States
Basic Materials
52
13.29%
11.72 B
$ 37.84
United States
Energy
53
13.27%
379.44 M
$ 50.36
United States
Energy
54
13.27%
1.97 B
$ 31.86
United States
Financial Services
55
13.16%
318.28 M
$ 1.52
United States
Energy
56
12.8%
568.33 M
$ 3.82
United States
Energy
57
12.77%
267.55 M
$ 6.3
United States
Basic Materials
58
12.62%
2.70 B
$ 50.41
United States
Energy
59
12.58%
439.98 M
$ 5.13
United States
Communication Services
60
12.26%
372.14 M
$ 230
United States
Energy
61
12.17%
177.46 M
$ 20.28
United States
Financial Services
62
12.14%
5.50 B
$ 90.25
United States
Consumer Defensive
63
12.1%
3.93 B
$ 79.55
United States
Energy
64
11.88%
20.85 B
$ 331.77
United States
Consumer Cyclical
65
11.83%
8.00 B
$ 33.63
United States
Consumer Defensive
66
11.82%
9.30 B
$ 595.2
United States
Consumer Cyclical
67
11.74%
5.52 B
$ 16.61
United States
Technology
68
11.55%
184.31 M
$ 8.47
United States
Financial Services
69
11.44%
4.04 B
$ 20.09
United States
Consumer Cyclical
70
11.27%
1.26 B
$ 13.97
Brazil
Consumer Defensive
71
11.21%
10.55 B
$ 160.42
United States
Consumer Cyclical
72
11.12%
2.10 B
$ 126.51
United States
Industrials
73
11.09%
398.94 M
$ 23.43
United States
Financial Services
74
11.04%
32.48 B
$ 97.85
United States
Consumer Defensive
75
11.02%
17.46 B
$ 29.08
United States
Technology
76
10.8%
2.63 B
$ 75.94
Bermuda
Energy
77
10.79%
6.08 B
$ 179.02
United States
Industrials
78
10.73%
556.06 M
$ 15.1
United States
Energy
79
10.62%
5.52 B
$ 54.81
United States
Technology
80
10.59%
344.28 M
$ 31.46
United States
Consumer Cyclical
81
10.58%
488.18 M
$ 2.78
United States
Technology
82
10.55%
5.13 B
$ 65.44
Canada
Basic Materials
83
10.48%
175.65 M
$ 2.18
United States
Healthcare
84
10.32%
36.85 B
$ 58.91
United States
Energy
85
10.31%
30.18 B
$ 93
United States
Industrials
86
10.11%
73.22 B
$ 226.37
United States
Consumer Cyclical
87
10.08%
321.23 M
$ 3.25
United States
Healthcare
88
10.08%
6.55 B
$ 90.46
United States
Utilities
89
10.08%
70.53 B
$ 235.85
United States
Energy
90
10.06%
3.91 B
$ 87.1
United States
Consumer Cyclical
91
10.05%
1.53 B
$ 115.15
United States
Energy
92
10.01%
2.67 B
$ 65.47
United States
Consumer Defensive
93
9.9%
1.02 B
$ 119.77
United States
Financial Services
94
9.85%
191.31 M
$ 5.25
South Korea
Technology
95
9.8%
8.06 B
$ 31.6
United States
Consumer Cyclical
96
9.73%
3.27 B
$ 47.47
United States
Energy
97
9.73%
2.74 B
$ 2.24
China
Consumer Defensive
98
9.67%
76.21 B
$ 64
Canada
Energy
99
9.67%
138.13 B
$ 404
United States
Technology
100
9.52%
317.08 M
$ 65.96
United States
Financial Services
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q Which stock has gained the most in April 2022?
A

NKTX (Nkarta, Inc.) has the highest monthly gain in this ranking for April 2022, with a gain of 61%. Top performers this month include NKTX, RCMT, DDL.

Q What stocks gained the most in April 2022?
A

The biggest gainers in April 2022 were: NKTX (+61%), RCMT (+60%), DDL (+45%), CURR (+42%), TRVI (+42%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during April 2022. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during April 2022. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which sectors performed best in April 2022?
A

The top performing sectors in April 2022 included Healthcare, Industrials, Consumer Defensive, based on the stocks with highest monthly gains. NKTX led the Healthcare sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in April 2022. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner which tracks live intraday market activity across NYSE and NASDAQ.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.