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#1 NKTX leads with +61% April 2022

NKTX (Nkarta, Inc.) is the best performing stock in April 2022. Following are RCMT (+60%) and DDL (+45%). Top performing sectors: Real Estate (+33% avg, 1 in top 10), Healthcare (+27% avg, 3 in top 10), Industrials (+23% avg, 3 in top 10).

Top Stock Gainers April 2022 - Monthly Performance Ranked

Track the top performing stocks of April 2022 ranked by monthly price gain. See which stock gainers delivered the highest gains this month, with market caps over $100 million on Nasdaq and NYSE.
2022

This ranking shows the top performing stocks and biggest stock gainers during April 2022, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

April 2022 Stock Market Momentum

This page answers a current-month trend question with data: which NYSE and NASDAQ stocks have shown the strongest price gains so far in April 2022. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?

Data as of June 20, 2026 at 5:50 PM EDT

Rank
Symbol
Company Name
Apr Gain
Market Cap
Price
Country
Sector
1
61.19%
204.62 M
$ 2.86
United States
Healthcare
2
59.63%
186.97 M
$ 26.38
United States
Industrials
3
45.48%
448.25 M
$ 2.05
China
Consumer Defensive
4
42.17%
340.21 M
$ 3.03
Singapore
Technology
5
42.11%
2.44 B
$ 17.21
United States
Healthcare
6
35.73%
696.50 M
$ 17.07
Bermuda
Industrials
7
35.33%
366.58 M
$ 13.82
United States
Healthcare
8
33.05%
258.43 M
$ 16
United States
Real Estate
9
32.1%
1.58 B
$ 39.66
United States
Basic Materials
10
27.73%
236.05 M
$ 29.05
United States
Industrials
11
27.62%
100.79 M
$ 0.8218
Israel
Technology
12
23.48%
916.69 M
$ 19.45
United States
Utilities
13
22.7%
7.56 B
$ 13.33
United States
Technology
14
22.54%
205.90 M
$ 4.79
United States
Energy
15
21.73%
3.85 B
$ 13.1
United States
Energy
16
21.45%
976.55 M
$ 26.6
United States
Technology
17
20.81%
118.58 M
$ 2.98
United States
Energy
18
20.2%
456.74 M
$ 18.44
United States
Technology
19
20.04%
907.25 M
$ 7.18
United States
Energy
20
19.74%
1.88 B
$ 3.92
United States
Technology
21
19.21%
4.80 B
$ 84.02
United States
Consumer Defensive
22
18%
144.95 M
$ 3.11
United States
Energy
23
17.46%
4.41 B
$ 37.29
United States
Energy
24
17.43%
1.24 B
$ 5.85
Bermuda
Energy
25
17.41%
441.37 M
$ 13.14
United States
Consumer Cyclical
26
17.27%
6.32 B
$ 188.74
United States
Consumer Cyclical
27
17.16%
270.74 M
$ 16.79
United States
Basic Materials
28
17.03%
713.48 M
$ 27.48
United States
Consumer Cyclical
29
16.64%
2.98 B
$ 14.01
United States
Energy
30
16.41%
152.64 M
$ 2.78
United States
Industrials
31
16.38%
3.67 B
$ 197.05
United States
Consumer Cyclical
32
16.22%
3.03 B
$ 23.52
United States
Energy
33
16.17%
10.18 B
$ 551.26
United States
Consumer Cyclical
34
16.06%
2.88 B
$ 3.98
Canada
Energy
35
15.57%
170.52 M
$ 4.13
United States
Energy
36
15.37%
2.22 B
$ 40.35
United States
Consumer Defensive
37
15.19%
10.91 B
$ 321.66
Hong Kong
Technology
38
14.76%
2.36 B
$ 185.77
United States
Basic Materials
39
14.62%
192.33 M
$ 15.9
United States
Financial Services
40
14.52%
811.73 M
$ 3.15
United States
Healthcare
41
14.37%
565.31 M
$ 29.09
United States
Industrials
42
14.04%
264.31 M
$ 64.85
United States
Consumer Cyclical
43
14.04%
9.95 B
$ 227.05
United States
Financial Services
44
13.96%
4.01 B
$ 80.58
Monaco
Energy
45
13.79%
6.76 B
$ 103.86
United States
Healthcare
46
13.75%
1.18 B
$ 5.04
United States
Technology
47
13.54%
6.85 B
$ 112.3
United States
Consumer Cyclical
48
13.5%
160.32 M
$ 5.3
United States
Energy
49
13.47%
1.51 B
$ 9.78
United States
Basic Materials
50
13.29%
10.29 B
$ 33.22
United States
Energy
51
13.27%
376.05 M
$ 49.87
United States
Energy
52
13.27%
1.95 B
$ 31.72
United States
Financial Services
53
13.16%
289.39 M
$ 1.14
United States
Energy
54
12.8%
477.58 M
$ 3.21
United States
Energy
55
12.77%
247.36 M
$ 5.88
United States
Basic Materials
56
12.62%
2.68 B
$ 50.41
United States
Energy
57
12.58%
439.98 M
$ 5.13
United States
Communication Services
58
12.26%
283.62 M
$ 175.29
United States
Energy
59
12.17%
176.12 M
$ 20.34
United States
Financial Services
60
12.14%
4.65 B
$ 76.91
United States
Consumer Defensive
61
12.1%
4.18 B
$ 84.49
United States
Energy
62
11.88%
21.21 B
$ 336.95
United States
Consumer Cyclical
63
11.83%
6.50 B
$ 27.32
United States
Consumer Defensive
64
11.82%
8.67 B
$ 554.86
United States
Consumer Cyclical
65
11.74%
7.10 B
$ 21.36
United States
Technology
66
11.55%
211.34 M
$ 9.74
United States
Financial Services
67
11.44%
4.14 B
$ 20.56
United States
Consumer Cyclical
68
11.27%
1.29 B
$ 14.07
Brazil
Consumer Defensive
69
11.21%
11.52 B
$ 175.2
United States
Consumer Cyclical
70
11.12%
1.47 B
$ 90.56
United States
Industrials
71
11.09%
500.89 M
$ 29.42
United States
Financial Services
72
11.04%
34.04 B
$ 102.56
United States
Consumer Defensive
73
11.02%
18.44 B
$ 30.66
United States
Technology
74
10.8%
2.58 B
$ 74.45
Bermuda
Energy
75
10.79%
7.04 B
$ 207.4
United States
Industrials
76
10.73%
517.59 M
$ 14.02
United States
Energy
77
10.62%
6.88 B
$ 51.45
United States
Technology
78
10.59%
367.59 M
$ 33.59
United States
Consumer Cyclical
79
10.58%
450.92 M
$ 2.56
United States
Technology
80
10.55%
5.50 B
$ 70.2
Canada
Basic Materials
81
10.48%
178.87 M
$ 2.22
United States
Healthcare
82
10.32%
31.72 B
$ 50.72
United States
Energy
83
10.31%
38.40 B
$ 118.32
United States
Industrials
84
10.11%
74.68 B
$ 232.8
United States
Consumer Cyclical
85
10.08%
525.91 M
$ 5.26
United States
Healthcare
86
10.08%
6.40 B
$ 88.48
United States
Utilities
87
10.08%
70.17 B
$ 236.3
United States
Energy
88
10.06%
3.88 B
$ 87.24
United States
Consumer Cyclical
89
10.05%
1.34 B
$ 100.79
United States
Energy
90
10.01%
3.89 B
$ 95.4
United States
Consumer Defensive
91
9.9%
1.08 B
$ 126.49
United States
Financial Services
92
9.85%
215.73 M
$ 5.92
South Korea
Technology
93
9.8%
6.57 B
$ 25.8
United States
Consumer Cyclical
94
9.73%
7.78 B
$ 46.53
United States
Energy
95
9.73%
2.25 B
$ 1.84
China
Consumer Defensive
96
9.67%
65.33 B
$ 55.33
Canada
Energy
97
9.67%
257.21 B
$ 746.23
United States
Technology
98
9.52%
326.54 M
$ 67.96
United States
Financial Services
99
9.49%
128.83 M
$ 0.582
Israel
Consumer Cyclical
100
9.48%
7.50 B
$ 91.47
United States
Technology
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q Which stock has gained the most in April 2022?
A

NKTX (Nkarta, Inc.) has the highest monthly gain in this ranking for April 2022, with a gain of 61%. Top performers this month include NKTX, RCMT, DDL.

Q What stocks gained the most in April 2022?
A

The biggest gainers in April 2022 were: NKTX (+61%), RCMT (+60%), DDL (+45%), CURR (+42%), TRVI (+42%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during April 2022. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during April 2022. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which sectors performed best in April 2022?
A

The top performing sectors in April 2022 included Healthcare, Industrials, Consumer Defensive, based on the stocks with highest monthly gains. NKTX led the Healthcare sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in April 2022. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner which tracks live intraday market activity across NYSE and NASDAQ.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.