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MARKET LEADERS
52-WEEK LEADER
BW +3367%
Babcock & Wilcox Enter..
2022 YTD LEADER
BEAG +9999%
Bold Eagle Acquisition..
MAY 2022 LEADER
GYRE +164%
Gyre Therapeutics, Inc.
📈 52-Week Top 5 Full List →
1 BW +3367.2% 2 BE +1101.5% 3 PL +939.3% 4 AMPX +713.4% 5 CIEN +683.4%
📅 2022 YTD Top 5 Full List →
1 BEAG +9999.0% 2 SNWV +9999.0% 3 META +4326.4% 4 CLS +3559.3% 5 TSSI +3384.5%
🗓 May 2022 Top 5 Full List →
1 GYRE +163.8% 2 CBIO +162.7% 3 CMPX +108.9% 4 BKSY +99.4% 5 BMEA +83.0%
Quick Access: 52-Week 2022 YTD May 2022 Market Cap Dividends
#1 GYRE leads with +164% May 2022

GYRE (Gyre Therapeutics, Inc.) is the best performing stock in May 2022. Following are CBIO (+163%) and CMPX (+109%). Top performing sectors: Real Estate (+55% avg), Healthcare (+53% avg, 8 in top 10), Technology (+42% avg, 1 in top 10).

Top Stock Gainers May 2022 - Monthly Performance Ranked

Track the top performing stocks of May 2022 ranked by monthly price gain. See which stock gainers delivered the highest gains this month, with market caps over $100 million on Nasdaq and NYSE.
2022
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

This ranking shows the top performing stocks and biggest stock gainers during May 2022, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

May 2022 Stock Market Momentum

This page answers a current-month trend question with data: which NYSE and NASDAQ stocks have shown the strongest price gains so far in May 2022. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?

Data as of April 27, 2026 at 8:17 AM EDT

Rank
Symbol
Company Name
May Gain
Market Cap
Price
Country
Sector
1
GYRE
Gyre Therapeutics, Inc.
163.84%
679.38 M
$ 7.44
United States
Healthcare
2
CBIO
Crescent Biopharma, Inc.
162.66%
755.46 M
$ 24.8
United States
Healthcare
3
CMPX
Compass Therapeutics, Inc.
108.9%
905.84 M
$ 5.03
United States
Healthcare
4
BKSY
BlackSky Technology Inc.
99.39%
1.26 B
$ 33.83
United States
Industrials
5
BMEA
Biomea Fusion, Inc.
83%
136.65 M
$ 1.89
United States
Healthcare
6
BLTE
Belite Bio, Inc
70.46%
6.44 B
$ 161.26
United States
Healthcare
7
APLD
Applied Digital Corporation
63.73%
10.00 B
$ 34.98
United States
Technology
8
IMMX
Immix Biopharma, Inc.
62.12%
522.17 M
$ 9.85
United States
Healthcare
9
NVCT
Nuvectis Pharma, Inc.
61.44%
235.78 M
$ 8.9
United States
Healthcare
10
APYX
Apyx Medical Corporation
60.16%
155.60 M
$ 3.72
United States
Healthcare
11
PMTS
CPI Card Group Inc.
57.57%
208.24 M
$ 18.17
United States
Financial Services
12
PKOH
Park-Ohio Holdings Corp.
55.8%
410.09 M
$ 28.48
United States
Industrials
13
JAN
Janus Living, Inc.
54.77%
6.61 B
$ 25.11
United States
Real Estate
14
SIGA
SIGA Technologies, Inc.
54.74%
327.41 M
$ 4.57
United States
Healthcare
15
BHVN
Biohaven Ltd.
53.69%
1.49 B
$ 9.88
United States
Healthcare
16
ARRY
Array Technologies, Inc.
53.68%
1.24 B
$ 8.11
United States
Technology
17
CNTX
Context Therapeutics Inc.
50.34%
207.65 M
$ 2.26
United States
Healthcare
18
QUBT
Quantum Computing Inc.
49.34%
2.02 B
$ 8.94
United States
Technology
19
HDSN
Hudson Technologies, Inc.
49.03%
267.55 M
$ 6.3
United States
Basic Materials
20
SAVA
Cassava Sciences Inc
47.12%
114.97 M
$ 2.38
United States
Healthcare
21
WTI
W&T Offshore, Inc.
45.99%
568.33 M
$ 3.82
United States
Energy
22
BORR
Borr Drilling Limited
45.43%
1.75 B
$ 5.69
Bermuda
Energy
23
SQM
Sociedad Química y Minera d...
45.36%
25.36 B
$ 88.79
Chile
Basic Materials
24
VHI
Valhi, Inc.
44.89%
410.10 M
$ 14.49
United States
Basic Materials
25
MOD
Modine Manufacturing Company
44.68%
13.27 B
$ 251.7
United States
Consumer Cyclical
26
GFF
Griffon Corporation
42.98%
4.33 B
$ 93.03
United States
Industrials
27
TSAT
Telesat Corporation
42.75%
2.43 B
$ 47.69
Canada
Technology
28
PLAB
Photronics, Inc.
42.46%
3.08 B
$ 52.27
United States
Technology
29
VANI
Vivani Medical, Inc.
42.42%
114.27 M
$ 1.35
United States
Healthcare
30
BOOM
DMC Global Inc.
41.9%
131.31 M
$ 6.41
United States
Industrials
31
SHLS
Shoals Technologies Group, ...
41.82%
1.33 B
$ 7.93
United States
Technology
32
PANL
Pangaea Logistics Solutions...
40.08%
468.33 M
$ 7.17
United States
Industrials
33
AHCO
AdaptHealth Corp.
39.89%
1.74 B
$ 12.8
United States
Healthcare
34
SM
SM Energy Company
39.59%
6.90 B
$ 28.78
United States
Energy
35
ETNB
89bio, Inc.
38.71%
1.28 B
$ 8.65
United States
Healthcare
36
ONIT
Onity Group Inc.
38.31%
394.21 M
$ 46.26
United States
Financial Services
37
YMAB
Y-mAbs Therapeutics, Inc.
38.07%
390.32 M
$ 8.59
United States
Healthcare
38
ULH
Universal Logistics Holding...
37.19%
623.71 M
$ 23.67
United States
Industrials
39
STKL
SunOpta Inc.
36.97%
769.79 M
$ 6.49
United States
Consumer Defensive
40
RGC
Regencell Bioscience Holdin...
36.91%
13.59 B
$ 27.49
Hong Kong
Healthcare
41
ASRT
Assertio Holdings, Inc.
36.82%
116.45 M
$ 18.04
United States
Healthcare
42
ALB
Albemarle Corporation
36.05%
22.20 B
$ 188.33
United States
Basic Materials
43
HRB
H&R Block, Inc.
36.01%
3.84 B
$ 30.26
United States
Consumer Cyclical
44
POWL
Powell Industries, Inc.
35.96%
9.21 B
$ 252.76
United States
Industrials
45
PBT
Permian Basin Royalty Trust
35.83%
1.04 B
$ 22.24
United States
Energy
46
UDMY
Udemy, Inc.
35.82%
620.23 M
$ 4.25
United States
Consumer Defensive
47
TTI
TETRA Technologies, Inc.
35.68%
1.31 B
$ 9.69
United States
Industrials
48
NL
NL Industries, Inc.
35.6%
291.71 M
$ 5.97
United States
Industrials
49
CVI
CVR Energy, Inc.
35.23%
3.17 B
$ 31.52
United States
Energy
50
DLNG
Dynagas LNG Partners LP
35.08%
143.35 M
$ 3.94
Greece
Energy
51
ENVX
Enovix Corporation
34.71%
1.44 B
$ 6.61
United States
Industrials
52
ESEA
Euroseas Ltd.
34.68%
480.01 M
$ 68.03
Greece
Industrials
53
NC
NACCO Industries, Inc.
33.57%
379.44 M
$ 50.36
United States
Energy
54
TRMD
TORM plc
33.47%
3.21 B
$ 31.16
United Kingdom
Energy
55
AMPY
Amplify Energy Corp.
33.28%
241.12 M
$ 5.84
United States
Energy
56
CWCO
Consolidated Water Co. Ltd.
33.11%
539.53 M
$ 33.72
Cayman Islands
Utilities
57
DSX
Diana Shipping Inc.
32.91%
301.44 M
$ 2.44
Greece
Industrials
58
NOG
Northern Oil and Gas, Inc.
32.83%
2.83 B
$ 26.71
United States
Energy
59
OPT
Opthea Limited
32.76%
524.82 M
$ 3.41
Australia
Healthcare
60
TMDX
TransMedics Group, Inc.
32.59%
3.83 B
$ 110.93
United States
Healthcare
61
DGICB
Donegal Group Inc.
32.56%
767.91 M
$ 19.76
United States
Financial Services
62
CIVI
Civitas Resources, Inc.
32.55%
2.34 B
$ 27.38
United States
Energy
63
BWLP
BW LPG Limited
32.46%
2.82 B
$ 18.55
Singapore
Industrials
64
AMBC
Ambac Financial Group, Inc.
32.22%
413.90 M
$ 8.92
United States
Financial Services
65
CECO
CECO Environmental Corp.
31.79%
2.33 B
$ 64.885
United States
Industrials
66
THS
Treehouse Foods Inc
31.58%
1.23 B
$ 24.43
United States
Consumer Defensive
67
SLQT
SelectQuote, Inc.
31.53%
160.39 M
$ 0.9098
United States
Financial Services
68
ELTX
Elicio Therapeutics, Inc.
31.34%
215.05 M
$ 11.69
United States
Healthcare
69
TWI
Titan International, Inc.
31.29%
526.28 M
$ 8.22
United States
Industrials
70
BYRN
Byrna Technologies Inc.
31.27%
139.52 M
$ 6.15
United States
Industrials
71
MLTX
MoonLake Immunotherapeutics
31.02%
1.25 B
$ 17.18
Switzerland
Healthcare
72
DXPE
DXP Enterprises, Inc.
30.66%
2.63 B
$ 169.51
United States
Industrials
73
GNE
Genie Energy Ltd.
30.63%
369.12 M
$ 13.82
United States
Utilities
74
CC
The Chemours Company
30.18%
3.99 B
$ 26.61
United States
Basic Materials
75
TNK
Teekay Tankers Ltd.
29.87%
2.63 B
$ 75.94
Bermuda
Energy
76
BODI
The Beachbody Company, Inc.
29.48%
112.07 M
$ 15.49
United States
Communication Services
77
QUIK
QuickLogic Corporation
29.25%
231.78 M
$ 13.08
United States
Technology
78
GHLD
Guild Holdings Company
28.99%
1.24 B
$ 19.95
United States
Financial Services
79
AXGN
Axogen, Inc.
28.93%
2.04 B
$ 39.25
United States
Healthcare
80
DVN
Devon Energy Corporation
28.36%
29.79 B
$ 47.94
United States
Energy
81
AVIR
Atea Pharmaceuticals, Inc.
28.34%
435.81 M
$ 5.47
United States
Healthcare
82
BSGM
BioSig Technologies, Inc.
28.23%
215.15 M
$ 6.1
United States
Healthcare
83
EVLV
Evolv Technologies Holdings...
28.19%
1.19 B
$ 6.63
United States
Industrials
84
CLPT
ClearPoint Neuro, Inc.
28.19%
353.24 M
$ 11.78
United States
Healthcare
85
SD
SandRidge Energy, Inc.
28.17%
556.06 M
$ 15.1
United States
Energy
86
CRMT
America's Car-Mart, Inc.
28.15%
103.03 M
$ 12.41
United States
Consumer Cyclical
87
UTHR
United Therapeutics Corpora...
28.09%
24.86 B
$ 567.16
United States
Healthcare
88
STNG
Scorpio Tankers Inc.
28.05%
3.95 B
$ 78.37
Monaco
Energy
89
RGTI
Rigetti Computing, Inc.
27.56%
5.52 B
$ 16.61
United States
Technology
90
DVAX
Dynavax Technologies Corp
27.53%
1.82 B
$ 15.5
United States
Healthcare
91
MNKD
MannKind Corporation
27.44%
833.75 M
$ 2.7
United States
Healthcare
92
TDW
Tidewater Inc.
27.19%
4.39 B
$ 88.52
United States
Energy
93
HUSA
Houston American Energy Corp.
26.72%
239.27 M
$ 7.07
United States
Energy
94
RTLR
Rattler Midstream LP
26.59%
2.23 B
$ 15.22
95
DINO
HF Sinclair Corporation
25.93%
10.86 B
$ 60.26
United States
Energy
96
COKE
Coca-Cola Consolidated, Inc.
25.89%
13.02 B
$ 195.59
United States
Consumer Defensive
97
NWPX
NWPX Infrastructure, Inc.
25.89%
817.03 M
$ 84.78
United States
Basic Materials
98
SJT
San Juan Basin Royalty Trust
25.88%
195.76 M
$ 4.2
United States
Energy
99
CSPI
CSP Inc.
25.81%
101.11 M
$ 10.2
United States
Technology
100
CVE
Cenovus Energy Inc.
25.65%
49.42 B
$ 26.29
Canada
Energy
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q Which stock has gained the most in May 2022?
A

GYRE (Gyre Therapeutics, Inc.) has the highest monthly gain in this ranking for May 2022, with a gain of 164%. Top performers this month include GYRE, CBIO, CMPX.

Q What stocks gained the most in May 2022?
A

The biggest gainers in May 2022 were: GYRE (+164%), CBIO (+163%), CMPX (+109%), BKSY (+99%), BMEA (+83%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during May 2022. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during May 2022. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which sectors performed best in May 2022?
A

The top performing sectors in May 2022 included Healthcare, Industrials, based on the stocks with highest monthly gains. GYRE led the Healthcare sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in May 2022. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner which tracks live intraday market activity across NYSE and NASDAQ.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.