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Top Stock Gainers May 2022 - Monthly Performance Ranked

The top US-listed stocks of May 2022 by monthly gain, on split-adjusted closes. Ranks 3,414 companies above $100M on NYSE, Nasdaq and NYSE American.

Looking for intraday moves instead? Today's stock movers ranks the current session's alert board, so it measures against whichever session is running rather than covering a fixed window.

2022
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

May 2022 ranking, complete through May 31, 2022

29 stocks are withheld from this ranking because their price history is under review.

The gain covers the period; price, market cap, sector and country show each company as it is today.

Swipe or scroll the table sideways for more columns.

Rank
Symbol
Company Name
May Gain
Market Cap (today)
Price (today)
Country
Sector
1
GYRE
Gyre Therapeutics Inc
+163.84%
$732.69M
$6.91
United States
Healthcare
2
CBIO
Crescent Biopharma Inc
+162.66%
$637.02M
$17.15
United States
Healthcare
3
CMPX
Compass Therapeutics Inc
+108.90%
$432.21M
$2.40
United States
Healthcare
4
BKSY
Blacksky Technology Inc
+99.39%
$1.14B
$27.75
United States
Industrials
5
BLTE
Belite Bio, Inc
+70.46%
$6.49B
$161.06
United States
Healthcare
6
APLD
Applied Digital
+63.73%
$7.74B
$27.21
United States
Technology
7
IMMX
Immix Biopharma Inc
+62.12%
$972.45M
$13.66
United States
Healthcare
8
NVCT
Nuvectis Pharma, Inc.
+61.44%
$767.62M
$23.56
United States
Healthcare
9
APYX
Apyx Medical Corporation
+60.16%
$131.43M
$3.12
United States
Healthcare
10
PMTS
CPI Card Group Inc.
+57.57%
$323.32M
$28.04
United States
Financial Services
11
PKOH
Park-Ohio Hldgs Corp
+55.80%
$662.19M
$45.70
United States
Industrials
12
SIGA
Siga Technologie
+54.74%
$218.42M
$3.04
United States
Healthcare
13
ARRY
Array Technologies, Inc.
+53.68%
$721.45M
$4.69
United States
Technology
14
QUBT
Quantum Computing Inc
+49.34%
$2.02B
$8.92
United States
Technology
15
HDSN
Hudson Tech
+49.03%
$236.96M
$5.63
United States
Basic Materials
16
SAVA
Cassava Sciences
+47.12%
$114.97M
$2.38
United States
Healthcare
17
WTI
W&T Offshore
+45.99%
$591.70M
$3.92
United States
Energy
18
BORR
BORR DRILLING LTD
+45.43%
$1.39B
$4.50
Bermuda
Energy
19
SQM
Sociedad Quimica y Minera
+45.36%
$23.41B
$81.96
Chile
Basic Materials
20
VHI
Valhi
+44.89%
$475.51M
$16.79
United States
Basic Materials
21
MOD
Modine Manf
+44.68%
$10.50B
$197.68
United States
Consumer Cyclical
22
GFF
Griffon Corp
+42.98%
$4.61B
$100.55
United States
Industrials
23
TSAT
TELESAT CORP
+42.75%
$2.28B
$44.29
Canada
Technology
24
PLAB
Photronics Inc
+42.46%
$1.80B
$30.51
United States
Technology
25
VANI
Vivani Medical
+42.42%
$124.48M
$1.38
United States
Healthcare
26
BOOM
Dmc Global Inc
+41.90%
$143.99M
$7.01
United States
Industrials
27
SHLS
Shoals Technologies Group, ...
+41.82%
$1.19B
$7.09
United States
Technology
28
PANL
Pangaea Logistics Solution Ltd
+40.08%
$532.96M
$8.14
United States
Industrials
29
AHCO
Adapthealth Corp
+39.89%
$751.09M
$5.63
United States
Healthcare
30
SM
Sm Energy
+39.59%
$8.85B
$37.20
United States
Energy
31
ETNB
89Bio, Inc.
+38.71%
$1.28B
$8.65
United States
Healthcare
32
ONIT
Onity Group Inc
+38.31%
$301.01M
$36.03
United States
Financial Services
33
YMAB
Y-Mabs Therapeutics
+38.07%
$390.32M
$8.59
United States
Healthcare
34
EXFY
Expensify, Inc.
+37.27%
$240.73M
$2.64
United States
Technology
35
ULH
Universal Logistics Hldgs Inc
+37.19%
$504.68M
$19.14
United States
Industrials
36
STKL
Sunopta Inc
+36.97%
$770.97M
$6.50
United States
Consumer Defensive
37
ASRT
Assertio Holdings Inc
+36.82%
$151.86M
$23.50
United States
Healthcare
38
ALB
Albemarle Corp
+36.05%
$16.90B
$143.25
United States
Basic Materials
39
HRB
Block (H.&R.), Inc.
+36.01%
$6.62B
$53.68
United States
Consumer Cyclical
40
POWL
Powell Inds
+35.96%
$7.20B
$197.67
United States
Industrials
41
PBT
Permian Basin
+35.83%
$1.60B
$34.27
United States
Energy
42
UDMY
Udemy, Inc.
+35.82%
$677.28M
$4.63
United States
Consumer Defensive
43
CVI
CVR Energy
+35.23%
$3.97B
$39.51
United States
Energy
44
DLNG
Dynagas Lng Partners Lp
+35.08%
$140.80M
$3.87
Greece
Energy
45
ENVX
Enovix Corporation
+34.71%
$741.74M
$3.38
United States
Industrials
46
ESEA
Euroseas
+34.68%
$529.37M
$75.03
Greece
Industrials
47
NC
NACCO Industries
+33.57%
$309.17M
$41.00
United States
Energy
48
TRMD
Torm Plc
+33.47%
$3.26B
$31.80
United Kingdom
Energy
49
AMPY
Amplify Energy Corp
+33.28%
$199.82M
$4.82
United States
Energy
50
CWCO
Consolidated Water
+33.11%
$471.74M
$29.46
Cayman Islands
Utilities
51
DSX
Diana Shipping Inc
+32.91%
$337.16M
$2.71
Greece
Industrials
52
NOG
Northern O & G
+32.83%
$2.91B
$27.34
United States
Energy
53
OPT
Opthea Ltd
+32.76%
$524.82M
$3.41
Australia
Healthcare
54
TMDX
Transmedics Group
+32.59%
$3.29B
$94.77
United States
Healthcare
55
DGICB
Donegal Group Inc
+32.56%
$916.48M
$24.69
United States
Financial Services
56
CIVI
Civitas Solns
+32.55%
$2.34B
$27.38
United States
Energy
57
BWLP
Bw Lpg
+32.46%
$3.75B
$24.72
Singapore
Energy
58
AMBC
Ambac Finl Group Inc
+32.22%
$413.90M
$8.92
United States
Financial Services
59
EEX
Emerald Holding Inc
+31.89%
$995.53M
$5.03
United States
Communication Services
60
CECO
Ceco Environmental Corp
+31.79%
$4.19B
$71.52
United States
Industrials
61
THS
Treehouse Foods
+31.58%
$1.23B
$24.43
United States
Consumer Defensive
62
SLQT
Selectquote Inc
+31.53%
$146.03M
$0.8281
United States
Financial Services
63
TWI
Titan Intl
+31.29%
$461.48M
$7.15
United States
Industrials
64
MLTX
MoonLake Immunotherapeutics
+31.02%
$1.34B
$15.76
Switzerland
Healthcare
65
DXPE
Dxp Enterprises Inc
+30.66%
$2.95B
$190.28
United States
Industrials
66
CC
Chemours Co
+30.18%
$2.40B
$15.97
United States
Basic Materials
67
TNK
Teekay Tankers
+29.87%
$3.16B
$91.02
Bermuda
Energy
68
QUIK
Quicklogic
+29.25%
$209.55M
$11.44
United States
Technology
69
GHLD
Guild Holdings Co
+28.99%
$1.24B
$19.95
United States
Financial Services
70
AXGN
Axogen Inc
+28.93%
$2.71B
$50.40
United States
Healthcare
71
XHG
XChange TEC
+28.75%
$227.33M
$4.41
China
Financial Services
72
AVIR
Atea Pharmaceuticals, Inc.
+28.34%
$435.51M
$5.43
United States
Healthcare
73
BSGM
BioSig Technologies Inc
+28.23%
$215.15M
$6.10
United States
Healthcare
74
CLPT
Clearpoint Neuro Inc
+28.19%
$469.46M
$15.39
United States
Healthcare
75
EVLV
Evolv Technologies Hldngs Inc
+28.19%
$960.51M
$5.34
United States
Industrials
76
SD
Sandridge Energy
+28.17%
$532.40M
$14.36
United States
Energy
77
UTHR
United Therapeutics Corp.
+28.09%
$22.01B
$513.12
United States
Healthcare
78
STNG
Scorpio Tankers
+28.05%
$3.93B
$78.49
Monaco
Energy
79
RGTI
Rigetti Computing Inc
+27.56%
$5.98B
$17.91
United States
Technology
80
DVAX
Dynavax Technolo
+27.53%
$1.82B
$15.50
United States
Healthcare
81
MNKD
Mannkind
+27.44%
$1.33B
$4.15
United States
Healthcare
82
TDW
Tidewater Inc
+27.19%
$4.74B
$95.25
United States
Energy
83
HUSA
Houston American
+26.72%
$239.27M
$7.07
United States
Energy
84
DINO
HF Sinclair Corp
+25.93%
$17.30B
$97.32
United States
Energy
85
COKE
Coca-Cola Consolidated Inc
+25.89%
$12.59B
$189.10
United States
Consumer Defensive
86
NWPX
NWPX Infrastructure Inc
+25.89%
$1.06B
$110.08
United States
Basic Materials
87
DLO
Dlocal Ltd
+25.35%
$4.46B
$15.17
Uruguay
Technology
88
OEC
Orion Engineered Carbons S.A.
+25.15%
$345.10M
$6.12
Luxembourg
Basic Materials
89
HAE
Haemonetics Corp Mass
+24.45%
$4.95B
$108.80
United States
Healthcare
90
KRO
Kronos Worldwide Inc
+24.43%
$943.80M
$8.20
United States
Basic Materials
91
SMRT
Smartrent Inc
+24.43%
$274.00M
$1.43
United States
Technology
92
GDYN
Grid Dynamics Hldgs Inc
+24.29%
$649.02M
$8.00
United States
Technology
93
SBR
Sabine Royalty
+24.04%
$1.08B
$73.75
United States
Energy
94
CHRD
Chord Energy Corp
+24.01%
$8.09B
$147.85
United States
Energy
95
DMLP
Dorchester Minerals Lp
+23.91%
$1.42B
$29.02
United States
Energy
96
DHX
Dhi Group Inc
+23.80%
$181.00M
$4.19
United States
Technology
97
SKYH
Sky Harbour Group
+23.78%
$841.82M
$10.45
United States
Real Estate
98
VIR
Vir Biotechnology, Inc.
+23.73%
$1.65B
$9.78
United States
Healthcare
99
PDS
Precision Drilng
+23.70%
$1.18B
$91.69
Canada
Energy
100
MTDR
Matador Res Co
+23.53%
$7.22B
$58.38
United States
Energy
Top gain on this page +163.84% GYRE
Rows on this page 100 ranks 1–100
Page 1 of 35
Period May 2022 closed

Best performing large-cap stocks in May 2022

SQM Sociedad Química y Minera d... +45.36% $23.41B
MOD Modine Manufacturing Company +44.68% $10.50B
ALB Albemarle Corporation +36.05% $16.90B
UTHR United Therapeutics Corpora... +28.09% $22.01B
DINO HF Sinclair Corporation +25.93% $17.30B

May 2022 Stock Market Momentum

This page answers a current-month trend question with data: which US-listed stocks have shown the strongest price gains so far in May 2022. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?
#1 GYRE leads with +164% May 2022

Among the 3,414 NYSE, Nasdaq and NYSE American stocks currently eligible for this ranking, GYRE (Gyre Therapeutics Inc) has the highest gain in May 2022 with +164%. Following are CBIO (+163%) and CMPX (+109%). Top performing sectors: Healthcare (+51% avg, 7 in top 10), Industrials (+41% avg, 1 in top 10), Consumer Cyclical (+40% avg).

MARKET LEADERS
52-WEEK LEADER
SNDK +3312%
SanDisk Corp
2022 YTD LEADER
NINE +1131%
NINE ENERGY SVC
MAY 2022 LEADER
GYRE +164%
Gyre Therapeutics Inc
52-Week Top 5 Full List →
1 SNDK +3311.9% 2 MGRT +2754.7% 3 AXTI +2390.8% 4 ERAS +1008.8% 5 NUAI +899.0%
2022 YTD Top 5 Full List →
1 NINE +1131.4% 2 META +689.1% 3 INDV +557.1% 4 TUSK +348.2% 5 RDUS +319.0%
May 2022 Top 5 Full List →
1 GYRE +163.8% 2 CBIO +162.7% 3 CMPX +108.9% 4 BKSY +99.4% 5 BLTE +70.5%
Quick Access: 52-Week 2022 YTD May 2022 Market Cap Dividends

This ranking shows the top performing stocks and biggest stock gainers during May 2022, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

Gains are computed on split-adjusted closes, so a split inside the month does not read as a move. This ranking is informational and is not investment advice.

Frequently Asked Questions

Q Which stock has gained the most in May 2022?
A

GYRE (Gyre Therapeutics Inc) has the highest monthly gain in this ranking for May 2022, with a gain of 164%. Top performers this month include GYRE, CBIO, CMPX.

Q What stocks gained the most in May 2022?
A

The biggest gainers in May 2022 were: GYRE (+164%), CBIO (+163%), CMPX (+109%), BKSY (+99%), BLTE (+70%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during May 2022. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during May 2022. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which companies does this ranking include?
A

3,414 companies with a market capitalization above $100 million traded on NYSE, Nasdaq and NYSE American, each with at least one trading day inside May 2022. One close inside the month is enough to qualify, so a company that listed during the month is ranked on the part of it that it traded.

Q Which sectors performed best in May 2022?
A

The top performing sectors in May 2022 included Healthcare, Industrials, based on the stocks with highest monthly gains. GYRE led the Healthcare sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in May 2022. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner, which tracks live intraday activity across US-listed symbols.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.