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Top Stock Gainers May 2022 - Monthly Performance Ranked

The top US-listed stocks of May 2022 by monthly gain, on split-adjusted closes. Ranks 3,840 companies above $100M on NYSE, Nasdaq and NYSE American.

Looking for intraday moves instead? Today's stock movers ranks the current session's alert board, so it measures against whichever session is running rather than covering a fixed window.

2022
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

May 2022 ranking, complete through May 31, 2022

The same month on news: the biggest gains on news in May 2022 and the biggest drops, each ranked by the move on the day its story landed.

28 stocks are withheld from this ranking because their price history is under review.

The gain covers the period; price, market cap, sector and country show each company as it is today.

Swipe or scroll the table sideways for more columns.

Rank
Symbol
Company Name
May Gain
Market Cap (today)
Price (today)
Country
Sector
1
GYRE
Gyre Therapeutics, Inc.
+163.84%
$686.04M
$6.47
United States
Healthcare
2
CBIO
Crescent Biopharma, Inc.
+162.66%
$467.31M
$12.58
United States
Healthcare
3
CMPX
Compass Therapeutics, Inc.
+108.90%
$158.30M
$0.8790
United States
Healthcare
4
BKSY
BlackSky Technology Inc.
+99.39%
$722.32M
$17.65
United States
Industrials
5
BLTE
Belite Bio, Inc
+70.46%
$6.15B
$152.72
United States
Healthcare
6
APLD
Applied Digital Corporation
+63.73%
$6.15B
$20.32
United States
Technology
7
IMMX
Immix Biopharma, Inc.
+62.12%
$705.50M
$8.51
United States
Healthcare
8
NVCT
Nuvectis Pharma, Inc.
+61.44%
$587.59M
$18.00
United States
Healthcare
9
APYX
Apyx Medical Corporation
+60.16%
$108.26M
$2.57
United States
Healthcare
10
PMTS
CPI Card Group Inc.
+57.57%
$293.39M
$25.31
United States
Financial Services
11
PKOH
Park-Ohio Holdings Corp
+55.80%
$685.38M
$47.30
United States
Industrials
12
SIGA
SIGA Technologies, Inc.
+54.74%
$222.73M
$3.10
United States
Healthcare
13
ARRY
Array Technologies, Inc.
+53.68%
$519.93M
$3.38
United States
Technology
14
QUBT
Quantum Computing Inc.
+49.34%
$1.43B
$6.31
United States
Technology
15
HDSN
Hudson Technologies Inc
+49.03%
$212.97M
$5.06
United States
Basic Materials
16
SAVA
Cassava Sciences, Inc.
+47.12%
$114.97M
$2.38
United States
Healthcare
17
WTI
W&T Offshore, Inc.
+45.99%
$550.94M
$3.65
United States
Energy
18
BORR
Borr Drilling Limited
+45.43%
$1.44B
$4.68
Bermuda
Energy
19
SQM
Sociedad Quimica y Minera de Chile SA
+45.36%
$17.61B
$61.64
Chile
Basic Materials
20
VHI
Valhi, Inc.
+44.89%
$405.84M
$14.33
United States
Basic Materials
21
MOD
Modine Manufacturing Co
+44.68%
$8.38B
$157.75
United States
Consumer Cyclical
22
GFF
Griffon Corp
+42.98%
$4.22B
$92.08
United States
Industrials
23
TSAT
Telesat Corporation
+42.75%
$2.27B
$44.23
Canada
Technology
24
PLAB
Photronics Inc
+42.46%
$1.67B
$28.36
United States
Technology
25
VANI
Vivani Medical, Inc.
+42.42%
$104.64M
$1.16
United States
Healthcare
26
BOOM
DMC Global Inc.
+41.90%
$110.10M
$5.36
United States
Industrials
27
SHLS
Shoals Technologies Group, Inc.
+41.82%
$1.32B
$7.84
United States
Technology
28
PANL
Pangaea Logistics Solutions Ltd.
+40.08%
$534.92M
$8.17
United States
Industrials
29
AHCO
AdaptHealth Corp.
+39.89%
$833.81M
$6.25
United States
Healthcare
30
SM
SM Energy Company
+39.59%
$9.09B
$38.22
United States
Energy
31
ETNB
89bio, Inc.
+38.71%
$1.28B
$8.65
United States
Healthcare
32
ONIT
Onity Group Inc.
+38.31%
$211.95M
$25.37
United States
Financial Services
33
YMAB
Y-mAbs Therapeutics, Inc.
+38.07%
$390.32M
$8.59
United States
Healthcare
34
EXFY
Expensify, Inc.
+37.27%
$223.41M
$2.45
United States
Technology
35
ULH
Universal Logistics Holdings, Inc.
+37.19%
$443.51M
$16.82
United States
Industrials
36
STKL
SunOpta, Inc.
+36.97%
$770.97M
$6.50
United States
Consumer Defensive
37
RGC
Regencell Bioscience Holdings Limited
+36.91%
$4.02B
$8.11
Hong Kong
Healthcare
38
ASRT
Assertio Holdings, Inc.
+36.82%
$151.86M
$23.50
United States
Healthcare
39
ALB
Albemarle Corporation
+36.05%
$11.56B
$97.97
United States
Basic Materials
40
HRB
H&R Block, Inc.
+36.01%
$5.64B
$46.02
United States
Consumer Cyclical
41
POWL
Powell Industries Inc
+35.96%
$6.18B
$169.53
United States
Industrials
42
PBT
Permian Basin Royalty Trust
+35.83%
$1.61B
$34.60
United States
Energy
43
UDMY
Udemy, Inc.
+35.82%
$677.28M
$4.63
United States
Consumer Defensive
44
TTI
TETRA Technologies, Inc.
+35.68%
$789.23M
$5.33
United States
Energy
45
CVI
CVR ENERGY, INC.
+35.23%
$6.23B
$61.96
United States
Energy
46
DLNG
DYNAGAS LNG PARNERS LP
+35.08%
$125.88M
$3.46
Greece
Energy
47
ENVX
Enovix Corporation
+34.71%
$535.45M
$2.44
United States
Industrials
48
ESEA
Euroseas Ltd.(Marshall Islands)
+34.68%
$486.47M
$68.95
Greece
Industrials
49
NC
NACCO Industries, Inc.
+33.57%
$256.53M
$34.02
United States
Energy
50
TRMD
TORM plc
+33.47%
$4.10B
$39.91
United Kingdom
Energy
51
AMPY
Amplify Energy Corp.
+33.28%
$179.92M
$4.34
United States
Energy
52
CWCO
Consolidated Water Co Inc
+33.11%
$467.74M
$29.21
Cayman Islands
Utilities
53
DSX
Diana Shipping, Inc.
+32.91%
$328.45M
$2.64
Greece
Industrials
54
NOG
Northern Oil and Gas, Inc.
+32.83%
$2.80B
$26.30
United States
Energy
55
OPT
Opthea Limited American
+32.76%
$524.82M
$3.41
Australia
Healthcare
56
TMDX
TransMedics Group, Inc.
+32.59%
$2.62B
$75.52
United States
Healthcare
57
DGICB
Donegal Group Inc
+32.56%
$918.70M
$24.75
United States
Financial Services
58
CIVI
Civitas Resources, Inc.
+32.55%
$2.34B
$27.38
United States
Energy
59
BWLP
BW LPG Limited
+32.46%
$3.78B
$24.89
Singapore
Energy
60
AMBC
Ambac Financial Group, Inc.
+32.22%
$413.90M
$8.92
United States
Financial Services
61
EEX
Emerald Holding, Inc.
+31.89%
$995.53M
$5.03
United States
Communication Services
62
CECO
Ceco Environmental Corp
+31.79%
$3.65B
$62.39
United States
Industrials
63
THS
Treehouse Foods, Inc.
+31.58%
$1.23B
$24.43
United States
Consumer Defensive
64
TWI
Titan International, Inc.(Delaware)
+31.29%
$433.08M
$6.71
United States
Industrials
65
BYRN
Byrna Technologies, Inc.
+31.27%
$108.83M
$4.65
United States
Industrials
66
MLTX
MoonLake Immunotherapeutics
+31.02%
$862.98M
$10.14
Switzerland
Healthcare
67
DXPE
DXP Enterprises Inc
+30.66%
$2.77B
$178.31
United States
Industrials
68
GNE
GENIE ENERGY LTD
+30.63%
$445.59M
$16.93
United States
Utilities
69
CC
The Chemours Company
+30.18%
$1.93B
$12.85
United States
Basic Materials
70
TNK
Teekay Tankers Ltd.
+29.87%
$3.52B
$101.56
Bermuda
Energy
71
QUIK
QuickLogic Corp
+29.25%
$173.65M
$9.48
United States
Technology
72
GHLD
Guild Holdings Company
+28.99%
$1.24B
$19.95
United States
Financial Services
73
AXGN
Axogen, Inc.
+28.93%
$2.06B
$35.14
United States
Healthcare
74
DVN
Devon Energy Corporation
+28.36%
$54.91B
$49.92
United States
Energy
75
AVIR
Atea Pharmaceuticals, Inc.
+28.34%
$371.35M
$4.63
United States
Healthcare
76
BSGM
BioSig Technologies, Inc.
+28.23%
$215.15M
$6.10
United States
Healthcare
77
CLPT
ClearPoint Neuro, Inc.
+28.19%
$281.86M
$9.24
United States
Healthcare
78
EVLV
Evolv Technologies Holdings, Inc.
+28.19%
$728.48M
$4.05
United States
Industrials
79
SD
SandRidge Energy, Inc.
+28.17%
$520.54M
$14.04
United States
Energy
80
UTHR
United Therapeutics Corp
+28.09%
$23.16B
$540.03
United States
Healthcare
81
STNG
Scorpio Tankers Inc.
+28.05%
$4.31B
$85.98
Monaco
Energy
82
RGTI
Rigetti Computing, Inc.
+27.56%
$3.90B
$11.68
United States
Technology
83
DVAX
Dynavax Technologies Corporation
+27.53%
$1.82B
$15.50
United States
Healthcare
84
MNKD
Mannkind Corporation
+27.44%
$971.06M
$3.02
United States
Healthcare
85
TDW
Tidewater, Inc.
+27.19%
$4.12B
$82.78
United States
Energy
86
HUSA
Houston American Energy Corp
+26.72%
$239.27M
$7.07
United States
Energy
87
DINO
HF Sinclair Corporation
+25.93%
$22.70B
$127.69
United States
Energy
88
COKE
Coca-Cola Consolidated, Inc.
+25.89%
$13.31B
$200.00
United States
Consumer Defensive
89
NWPX
NWPX Infrastructure, Inc.
+25.89%
$935.39M
$97.06
United States
Basic Materials
90
CVE
Cenovus Energy Inc.
+25.65%
$60.16B
$32.62
Canada
Energy
91
DLO
DLocal Limited
+25.35%
$4.32B
$14.69
Uruguay
Technology
92
OEC
Orion S.A.
+25.15%
$320.29M
$5.68
Luxembourg
Basic Materials
93
NRG
NRG Energy, Inc.
+24.97%
$21.20B
$100.85
United States
Utilities
94
ZKIN
ZK International Group Co., Ltd
+24.77%
$103.82M
$1.71
China
Basic Materials
95
KLXE
KLX Energy Services Holdings, Inc.
+24.69%
$137.65M
$1.31
United States
Energy
96
HAE
Haemonetics Corporation
+24.45%
$5.51B
$121.11
United States
Healthcare
97
KRO
Kronos Worldwide, Inc.
+24.43%
$842.51M
$7.32
United States
Basic Materials
98
SMRT
SmartRent, Inc.
+24.43%
$222.27M
$1.16
United States
Technology
99
GDYN
Grid Dynamics Holdings, Inc.
+24.29%
$622.24M
$7.67
United States
Technology
100
SBR
Sabine Royalty Trust
+24.04%
$1.06B
$72.43
United States
Energy
S&P 500 fund (SPY) -0.37%
Finished higher 49% of 3,840
Median move -0.2%
Leading sector Energy +11.3% median
Lagging sector Healthcare -4.8% median

Over May 2022, 49% of the 3,840 ranked companies finished higher and the median move was -0.2%; Energy led on median (+11.3%) and Healthcare lagged (-4.8%). The S&P 500 fund (SPY) moved -0.37% between its May 2, 2022 and May 31, 2022 closes. Each ranked company's gain runs from its own first close inside the period, so a company listed later in the period is measured over a shorter window.

Top gain on this page +163.84% GYRE
Rows on this page 100 ranks 1–100
Page 1 of 39
Period May 2022 closed

Best performing large-cap stocks in May 2022

SQM Sociedad Química y Minera d... +45.36% $17.61B
ALB Albemarle Corporation +36.05% $11.56B
DVN Devon Energy Corporation +28.36% $54.91B
UTHR United Therapeutics Corpora... +28.09% $23.16B
DINO HF Sinclair Corporation +25.93% $22.70B

May 2022 Stock Market Momentum

This page answers a current-month trend question with data: which US-listed stocks have shown the strongest price gains so far in May 2022. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?
#1 GYRE leads with +164% May 2022

Among the 3,840 NYSE, Nasdaq and NYSE American stocks currently eligible for this ranking, GYRE (Gyre Therapeutics, Inc.) has the highest gain in May 2022 with +164%. Following are CBIO (+163%) and CMPX (+109%). Top performing sectors: Healthcare (+52% avg, 7 in top 10), Industrials (+41% avg, 1 in top 10), Consumer Cyclical (+40% avg).

MARKET LEADERS
52-WEEK LEADER
MGRT +1886%
Mega Fortune Company L..
2022 YTD LEADER
NINE +1131%
Nine Energy Service, I..
MAY 2022 LEADER
GYRE +164%
Gyre Therapeutics, Inc.
52-Week Top 5 Full List →
1 MGRT +1885.7% 2 AXTI +1184.0% 3 SNDK +895.2% 4 MRNA +809.3% 5 ANL +637.2%
2022 YTD Top 5 Full List →
1 NINE +1131.4% 2 META +689.1% 3 INDV +557.1% 4 KLXE +394.6% 5 TUSK +348.2%
May 2022 Top 5 Full List →
1 GYRE +163.8% 2 CBIO +162.7% 3 CMPX +108.9% 4 BKSY +99.4% 5 BLTE +70.5%
Quick Access: 52-Week 2022 YTD May 2022 Market Cap Dividends

This ranking shows the top performing stocks and biggest stock gainers during May 2022, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

Gains are computed on split-adjusted closes, so a split inside the month does not read as a move. This ranking is informational and is not investment advice.
What this ranking covers
Universe
US-listed companies on NYSE, Nasdaq and NYSE American.
Floors
Market cap of at least $100 million, and one close inside the month to measure from.
Exclusions
Stocks whose price history is under review are withheld, and their count is stated above.
Measured on
Split-adjusted closes, from the first close inside the month to the last one in it.
Refreshed
Rebuilt once the session behind those closes has settled. The date above the table names that session, not the moment the table was written.

Frequently Asked Questions

Q Which stock has gained the most in May 2022?
A

GYRE (Gyre Therapeutics, Inc.) has the highest monthly gain in this ranking for May 2022, with a gain of 164%. Top performers this month include GYRE, CBIO, CMPX.

Q What stocks gained the most in May 2022?
A

The biggest gainers in May 2022 were: GYRE (+164%), CBIO (+163%), CMPX (+109%), BKSY (+99%), BLTE (+70%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during May 2022. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during May 2022. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which companies does this ranking include?
A

3,840 companies with a market capitalization above $100 million traded on NYSE, Nasdaq and NYSE American, each with at least one trading day inside May 2022. One close inside the month is enough to qualify, so a company that listed during the month is ranked on the part of it that it traded.

Q Which sectors performed best in May 2022?
A

The five highest-gaining companies in May 2022 sit in Healthcare, Industrials, with the leader GYRE in Healthcare. That describes the top of this list, not a sector ranking; the market-context strip above the table reports the median move of each sector's ranked companies.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the closing price on its first trading day, both split-adjusted. A company whose trading history begins inside the month is measured from its first close.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in May 2022. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner, which tracks live intraday activity across US-listed symbols.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.