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MARKET LEADERS
52-WEEK LEADER
WOLF +1961%
Wolfspeed, Inc.
2022 YTD LEADER
ENLT +4533%
Enlight Renewable Ener..
MAY 2022 LEADER
GYRE +164%
Gyre Therapeutics, Inc.
📈 52-Week Top 5 Full List →
1 WOLF +1961.4% 2 BW +851.0% 3 BE +747.6% 4 EVC +362.8% 5 CIEN +338.1%
📅 2022 YTD Top 5 Full List →
1 ENLT +4533.2% 2 META +4136.1% 3 SNDK +2687.7% 4 CLS +2588.1% 5 TRVI +2313.9%
🗓 May 2022 Top 5 Full List →
1 GYRE +163.8% 2 CBIO +162.7% 3 CMPX +108.9% 4 BKSY +99.4% 5 BLTE +70.5%
Quick Access: 52-Week 2022 YTD May 2022 Market Cap Dividends
#1 GYRE leads with +164% May 2022

GYRE (Gyre Therapeutics, Inc.) is the best performing stock in May 2022. Following are CBIO (+163%) and CMPX (+109%). Top performing sectors: Real Estate (+55% avg), Healthcare (+52% avg, 7 in top 10), Industrials (+41% avg, 1 in top 10).

Top Stock Gainers May 2022 - Monthly Performance Ranked

Track the top performing stocks of May 2022 ranked by monthly price gain. See which stock gainers delivered the highest gains this month, with market caps over $100 million on Nasdaq and NYSE.

Best performing large-cap stocks in May 2022

SQM Sociedad Química y Minera d... +45.36% $19.94B
MOD Modine Manufacturing Company +44.68% $12.18B
ALB Albemarle Corporation +36.05% $14.24B
DVN Devon Energy Corporation +28.36% $50.55B
UTHR United Therapeutics Corpora... +28.09% $22.74B
2022
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

This ranking shows the top performing stocks and biggest stock gainers during May 2022, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

May 2022 Stock Market Momentum

This page answers a current-month trend question with data: which NYSE and NASDAQ stocks have shown the strongest price gains so far in May 2022. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?

Data as of July 19, 2026 at 9:36 PM EDT

Rank
Symbol
Company Name
May Gain
Market Cap
Price
Country
Sector
1
GYRE
Gyre Therapeutics, Inc.
163.84%
674.51 M
$ 6.05
United States
Healthcare
2
CBIO
Crescent Biopharma, Inc.
162.66%
526.13 M
$ 14.75
United States
Healthcare
3
CMPX
Compass Therapeutics, Inc.
108.9%
369.18 M
$ 2.05
United States
Healthcare
4
BKSY
BlackSky Technology Inc.
99.39%
823.45 M
$ 22.19
United States
Industrials
5
BLTE
Belite Bio, Inc
70.46%
6.02 B
$ 150.08
United States
Healthcare
6
APLD
Applied Digital Corporation
63.73%
7.37 B
$ 25.79
United States
Technology
7
IMMX
Immix Biopharma, Inc.
62.12%
729.70 M
$ 10.25
United States
Healthcare
8
NVCT
Nuvectis Pharma, Inc.
61.44%
603.40 M
$ 19.14
United States
Healthcare
9
APYX
Apyx Medical Corporation
60.16%
180.23 M
$ 4.28
United States
Healthcare
10
PMTS
CPI Card Group Inc.
57.57%
215.86 M
$ 18.81
United States
Financial Services
11
PKOH
Park-Ohio Holdings Corp.
55.8%
543.67 M
$ 37.76
United States
Industrials
12
JAN
Janus Living, Inc.
54.77%
6.44 B
$ 30.35
United States
Real Estate
13
SIGA
SIGA Technologies, Inc.
54.74%
246.73 M
$ 3.44
United States
Healthcare
14
BHVN
Biohaven Ltd.
53.69%
2.32 B
$ 15.44
United States
Healthcare
15
ARRY
Array Technologies, Inc.
53.68%
939.88 M
$ 6.11
United States
Technology
16
QUBT
Quantum Computing Inc.
49.34%
1.76 B
$ 7.8
United States
Technology
17
HDSN
Hudson Technologies, Inc.
49.03%
259.56 M
$ 6.17
United States
Basic Materials
18
SAVA
Cassava Sciences Inc
47.12%
114.97 M
$ 2.38
United States
Healthcare
19
WTI
W&T Offshore, Inc.
45.99%
519.23 M
$ 3.49
United States
Energy
20
BORR
Borr Drilling Limited
45.43%
1.28 B
$ 4.16
Bermuda
Energy
21
SQM
Sociedad Química y Minera d...
45.36%
19.94 B
$ 69.81
Chile
Basic Materials
22
VHI
Valhi, Inc.
44.89%
393.12 M
$ 13.89
United States
Basic Materials
23
MOD
Modine Manufacturing Company
44.68%
12.18 B
$ 229.34
United States
Consumer Cyclical
24
GFF
Griffon Corporation
42.98%
4.20 B
$ 91.47
United States
Industrials
25
TSAT
Telesat Corporation
42.75%
1.87 B
$ 36.38
Canada
Technology
26
PLAB
Photronics, Inc.
42.46%
1.70 B
$ 28.85
United States
Technology
27
VANI
Vivani Medical, Inc.
42.42%
113.83 M
$ 1.32
United States
Healthcare
28
BOOM
DMC Global Inc.
41.9%
128.13 M
$ 6.26
United States
Industrials
29
SHLS
Shoals Technologies Group, ...
41.82%
1.73 B
$ 10.3
United States
Technology
30
PANL
Pangaea Logistics Solutions...
40.08%
459.87 M
$ 7.03
United States
Industrials
31
AHCO
AdaptHealth Corp.
39.89%
1.49 B
$ 10.96
United States
Healthcare
32
SM
SM Energy Company
39.59%
7.51 B
$ 31.32
United States
Energy
33
ETNB
89bio, Inc.
38.71%
1.28 B
$ 8.65
United States
Healthcare
34
ONIT
Onity Group Inc.
38.31%
344.12 M
$ 40.81
United States
Financial Services
35
YMAB
Y-mAbs Therapeutics, Inc.
38.07%
390.32 M
$ 8.59
United States
Healthcare
36
EXFY
Expensify, Inc.
37.27%
176.48 M
$ 1.83
United States
Technology
37
ULH
Universal Logistics Holding...
37.19%
376.82 M
$ 14.29
United States
Industrials
38
STKL
SunOpta Inc
36.97%
770.97 M
$ 6.5
United States
Consumer Defensive
39
RGC
Regencell Bioscience Holdin...
36.91%
2.48 B
$ 5.02
Hong Kong
Healthcare
40
ASRT
Assertio Holdings Inc
36.82%
151.86 M
$ 23.5
United States
Healthcare
41
ALB
Albemarle Corporation
36.05%
14.24 B
$ 120.78
United States
Basic Materials
42
HRB
H&R Block, Inc.
36.01%
5.33 B
$ 42.08
United States
Consumer Cyclical
43
POWL
Powell Industries, Inc.
35.96%
8.48 B
$ 232.79
United States
Industrials
44
PBT
Permian Basin Royalty Trust
35.83%
1.32 B
$ 28.4
United States
Energy
45
UDMY
Udemy, Inc.
35.82%
677.28 M
$ 4.63
United States
Consumer Defensive
46
TTI
TETRA Technologies, Inc.
35.68%
1.37 B
$ 9.26
United States
Industrials
47
NL
NLI Holdings, Inc.
35.6%
288.50 M
$ 5.9
United States
Industrials
48
CVI
CVR Energy, Inc.
35.23%
3.53 B
$ 35.13
United States
Energy
49
DLNG
Dynagas LNG Partners LP
35.08%
122.61 M
$ 3.37
Greece
Energy
50
ENVX
Enovix Corporation
34.71%
1.03 B
$ 4.72
United States
Industrials
51
ESEA
Euroseas Ltd.
34.68%
488.44 M
$ 69.23
Greece
Industrials
52
NC
NACCO Industries, Inc.
33.57%
361.72 M
$ 47.97
United States
Energy
53
TRMD
TORM plc
33.47%
2.91 B
$ 28.45
United Kingdom
Energy
54
AMPY
Amplify Energy Corp.
33.28%
162.67 M
$ 3.94
United States
Energy
55
CWCO
Consolidated Water Co. Ltd.
33.11%
466.73 M
$ 29.17
Cayman Islands
Utilities
56
DSX
Diana Shipping Inc.
32.91%
255.03 M
$ 2.05
Greece
Industrials
57
NOG
Northern Oil and Gas, Inc.
32.83%
2.31 B
$ 21.19
United States
Energy
58
OPT
Opthea Limited
32.76%
524.82 M
$ 3.41
Australia
Healthcare
59
TMDX
TransMedics Group, Inc.
32.59%
2.56 B
$ 73.98
United States
Healthcare
60
DGICB
Donegal Group Inc.
32.56%
820.65 M
$ 22.15
United States
Financial Services
61
CIVI
Civitas Resources, Inc.
32.55%
2.34 B
$ 27.38
United States
Energy
62
BWLP
BW LPG Limited
32.46%
3.09 B
$ 20.37
Singapore
Energy
63
AMBC
Ambac Financial Group, Inc.
32.22%
413.90 M
$ 8.92
United States
Financial Services
64
EEX
Emerald Holding, Inc.
31.89%
997.51 M
$ 5.04
United States
Communication Services
65
CECO
CECO Environmental Corp.
31.79%
4.67 B
$ 79.93
United States
Industrials
66
THS
Treehouse Foods Inc
31.58%
1.23 B
$ 24.43
United States
Consumer Defensive
67
SLQT
SelectQuote, Inc.
31.53%
126.60 M
$ 0.7179
United States
Financial Services
68
TWI
Titan International, Inc.
31.29%
493.09 M
$ 7.66
United States
Industrials
69
MLTX
MoonLake Immunotherapeutics
31.02%
1.64 B
$ 19.68
Switzerland
Healthcare
70
DXPE
DXP Enterprises, Inc.
30.66%
2.60 B
$ 167.98
United States
Industrials
71
GNE
Genie Energy Ltd.
30.63%
369.39 M
$ 13.99
United States
Utilities
72
CC
The Chemours Company
30.18%
2.63 B
$ 17.52
United States
Basic Materials
73
TNK
Teekay Tankers Ltd.
29.87%
2.43 B
$ 70.07
Bermuda
Energy
74
QUIK
QuickLogic Corporation
29.25%
230.41 M
$ 13
United States
Technology
75
GHLD
Guild Holdings Company
28.99%
1.24 B
$ 19.95
United States
Financial Services
76
AXGN
Axogen, Inc.
28.93%
2.12 B
$ 39.85
United States
Healthcare
77
DVN
Devon Energy Corporation
28.36%
50.55 B
$ 43.83
United States
Energy
78
AVIR
Atea Pharmaceuticals, Inc.
28.34%
389.73 M
$ 4.87
United States
Healthcare
79
BSGM
BioSig Technologies, Inc.
28.23%
215.15 M
$ 6.1
United States
Healthcare
80
CLPT
ClearPoint Neuro, Inc.
28.19%
454.34 M
$ 15.15
United States
Healthcare
81
EVLV
Evolv Technologies Holdings...
28.19%
1.02 B
$ 5.66
United States
Industrials
82
SD
SandRidge Energy, Inc.
28.17%
503.20 M
$ 13.63
United States
Energy
83
UTHR
United Therapeutics Corpora...
28.09%
22.74 B
$ 535.67
United States
Healthcare
84
STNG
Scorpio Tankers Inc.
28.05%
3.81 B
$ 76.49
Monaco
Energy
85
RGTI
Rigetti Computing, Inc.
27.56%
4.69 B
$ 14.11
United States
Technology
86
DVAX
Dynavax Technologies Corp
27.53%
1.82 B
$ 15.5
United States
Healthcare
87
MNKD
MannKind Corporation
27.44%
1.25 B
$ 4.03
United States
Healthcare
88
TDW
Tidewater Inc.
27.19%
3.77 B
$ 75.82
United States
Energy
89
HUSA
Houston American Energy Corp.
26.72%
239.27 M
$ 7.07
United States
Energy
90
RTLR
Rattler Midstream LP
26.59%
2.23 B
$ 15.22
91
DINO
HF Sinclair Corporation
25.93%
15.97 B
$ 88.59
United States
Energy
92
COKE
Coca-Cola Consolidated, Inc.
25.89%
12.03 B
$ 180.74
United States
Consumer Defensive
93
NWPX
NWPX Infrastructure, Inc.
25.89%
1.33 B
$ 138.2
United States
Basic Materials
94
SJT
San Juan Basin Royalty Trust
25.88%
125.84 M
$ 2.7
United States
Energy
95
CVE
Cenovus Energy Inc.
25.65%
52.12 B
$ 27.95
Canada
Energy
96
DLO
DLocal Limited
25.35%
4.26 B
$ 14.48
Uruguay
Technology
97
OEC
Orion S.A.
25.15%
386.26 M
$ 6.85
Luxembourg
Basic Materials
98
NRG
NRG Energy, Inc.
24.97%
27.24 B
$ 129.11
United States
Utilities
99
HAE
Haemonetics Corporation
24.45%
3.54 B
$ 77.86
United States
Healthcare
100
KRO
Kronos Worldwide, Inc.
24.43%
757.05 M
$ 6.58
United States
Basic Materials
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q Which stock has gained the most in May 2022?
A

GYRE (Gyre Therapeutics, Inc.) has the highest monthly gain in this ranking for May 2022, with a gain of 164%. Top performers this month include GYRE, CBIO, CMPX.

Q What stocks gained the most in May 2022?
A

The biggest gainers in May 2022 were: GYRE (+164%), CBIO (+163%), CMPX (+109%), BKSY (+99%), BLTE (+70%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during May 2022. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during May 2022. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which sectors performed best in May 2022?
A

The top performing sectors in May 2022 included Healthcare, Industrials, based on the stocks with highest monthly gains. GYRE led the Healthcare sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in May 2022. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner which tracks live intraday market activity across NYSE and NASDAQ.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.