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MARKET LEADERS
52-WEEK LEADER
WOLF +4039%
Wolfspeed, Inc.
2025 YTD LEADER
RGC +9999%
Regencell Bioscience H..
APR 2025 LEADER
CEP +292%
Cantor Equity Partners..
📈 52-Week Top 5 Full List →
1 WOLF +4038.9% 2 BE +1305.0% 3 BW +1209.6% 4 TE +974.8% 5 CIEN +749.2%
📅 2025 YTD Top 5 Full List →
1 RGC +9999.0% 2 AXTI +4772.1% 3 TOI +1341.7% 4 HYMC +1310.1% 5 RLMD +1306.3%
🗓 April 2025 Top 5 Full List →
1 CEP +291.9% 2 PNBK +240.1% 3 AREC +122.9% 4 RGC +107.0% 5 THTX +102.9%
Quick Access: 52-Week 2025 YTD Apr 2025 Market Cap Dividends
#1 CEP leads with +292% April 2025

CEP (Cantor Equity Partners, Inc. Class A Ordinary Shares) is the best performing stock in April 2025. Following are PNBK (+240%) and AREC (+123%). Top performing sectors: Financial Services (+161% avg, 2 in top 10), Communication Services (+79% avg), Consumer Cyclical (+58% avg).

Top Stock Gainers April 2025 - Monthly Performance Ranked

Track the top performing stocks of April 2025 ranked by monthly price gain. See which stock gainers delivered the highest gains this month, with market caps over $100 million on Nasdaq and NYSE.
2025
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

This ranking shows the top performing stocks and biggest stock gainers during April 2025, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

April 2025 Stock Market Momentum

This page answers a current-month trend question with data: which NYSE and NASDAQ stocks have shown the strongest price gains so far in April 2025. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?

Data as of June 4, 2026 at 2:21 AM EDT

Rank
Symbol
Company Name
Apr Gain
Market Cap
Price
Country
Sector
1
CEP
Cantor Equity Partners, Inc...
291.91%
223.51 M
$ 21.7
United States
Financial Services
2
PNBK
Patriot National Bancorp, Inc.
240.08%
130.53 M
$ 1.11
United States
Financial Services
3
AREC
American Resources Corporation
122.93%
293.10 M
$ 2.74
United States
Basic Materials
4
RGC
Regencell Bioscience Holdin...
106.96%
11.45 B
$ 23.15
Hong Kong
Healthcare
5
THTX
Theratechnologies Inc.
102.86%
150.81 M
$ 3.28
Canada
Healthcare
6
TOI
The Oncology Institute, Inc.
96.83%
458.92 M
$ 4.59
United States
Healthcare
7
KPTI
Karyopharm Therapeutics Inc.
90.68%
209.18 M
$ 9.23
United States
Healthcare
8
TMC
TMC the metals company Inc.
89.16%
3.62 B
$ 6.49
Canada
Basic Materials
9
BSGM
BioSig Technologies, Inc.
85.59%
215.15 M
$ 6.1
United States
Healthcare
10
HTZ
Hertz Global Holdings, Inc.
83.33%
1.65 B
$ 5.21
United States
Industrials
11
TDUP
ThredUp Inc.
82.52%
580.68 M
$ 4.5
United States
Consumer Cyclical
12
AGEN
Agenus Inc.
80.63%
140.75 M
$ 3.38
United States
Healthcare
13
ANTE
AirNet Technology Inc.
79.26%
546.93 M
$ 4.94
China
Communication Services
14
RZLV
Rezolve AI PLC
77.69%
1.14 B
$ 2.85
United Kingdom
Technology
15
STRO
Sutro Biopharma, Inc.
76.38%
404.82 M
$ 24.43
United States
Healthcare
16
MIST
Milestone Pharmaceuticals Inc.
73.68%
164.34 M
$ 1.32
Canada
Healthcare
17
ICAD
iCAD, Inc.
72.73%
106.31 M
$ 3.87
United States
Healthcare
18
GPCR
Structure Therapeutics Inc.
70.99%
2.64 B
$ 37.19
United States
Healthcare
19
KOD
Kodiak Sciences Inc.
70.31%
2.08 B
$ 33.215
United States
Healthcare
20
FRGE
Forge Global Holdings Inc
69.33%
623.01 M
$ 45
United States
Financial Services
21
FATE
Fate Therapeutics, Inc.
69.07%
299.56 M
$ 2.57
United States
Healthcare
22
ABAT
American Battery Technology...
67.65%
537.47 M
$ 3.94
United States
Industrials
23
USAR
USA Rare Earth, Inc.
67.36%
6.85 B
$ 30.7
United States
Basic Materials
24
MBOT
Microbot Medical Inc.
65.77%
135.00 M
$ 2.01
United States
Healthcare
25
SES
SES AI Corporation
63.6%
531.77 M
$ 1.44
United States
Consumer Cyclical
26
IFRX
InflaRx N.V.
61.9%
319.63 M
$ 2.17
Germany
Healthcare
27
XGN
Exagen Inc.
58.52%
116.45 M
$ 4.82
United States
Healthcare
28
LXRX
Lexicon Pharmaceuticals, Inc.
57.47%
839.53 M
$ 1.89
United States
Healthcare
29
CNTX
Context Therapeutics Inc.
57.32%
222.35 M
$ 2.42
United States
Healthcare
30
STOK
Stoke Therapeutics, Inc.
56.66%
1.79 B
$ 28.68
United States
Healthcare
31
SPAI
Safe Pro Group Inc.
56.27%
122.89 M
$ 5.96
United States
Industrials
32
NGNE
Neurogene Inc.
55.36%
413.06 M
$ 26.14
United States
Healthcare
33
GSIT
GSI Technology, Inc.
54.81%
378.15 M
$ 10.45
United States
Technology
34
SLGL
Sol-Gel Technologies Ltd.
54.69%
241.02 M
$ 73.73
Israel
Healthcare
35
OLMA
Olema Pharmaceuticals, Inc.
54.49%
933.74 M
$ 10.69
United States
Healthcare
36
NUTX
Nutex Health Inc.
54.02%
860.37 M
$ 125.03
United States
Healthcare
37
THRD
Third Harmonic Bio, Inc.
53.87%
242.79 M
$ 5.38
United States
Healthcare
38
TSHA
Taysha Gene Therapies, Inc.
53.36%
1.64 B
$ 5.69
United States
Healthcare
39
AMLX
Amylyx Pharmaceuticals, Inc.
52.99%
1.48 B
$ 13.29
United States
Healthcare
40
MBX
MBX Biosciences, Inc.
52.92%
1.46 B
$ 30.7
United States
Healthcare
41
SLN
Silence Therapeutics plc
52.89%
300.88 M
$ 6.37
United Kingdom
Healthcare
42
GYRE
Gyre Therapeutics, Inc.
52.26%
539.48 M
$ 5.56
United States
Healthcare
43
CRMD
CorMedix Inc.
51.4%
640.95 M
$ 8.17
United States
Healthcare
44
KROS
Keros Therapeutics, Inc.
51.2%
208.80 M
$ 10.55
United States
Healthcare
45
NVFY
Nova LifeStyle, Inc.
51.11%
115.31 M
$ 4.95
United States
Consumer Cyclical
46
ROMA
Roma Green Finance Limited
50.64%
453.88 M
$ 7.62
Hong Kong
Industrials
47
QURE
uniQure N.V.
48.94%
1.69 B
$ 26.76
Netherlands
Healthcare
48
ALMU
Aeluma, Inc.
48.51%
486.19 M
$ 26.56
United States
Technology
49
CRBP
Corbus Pharmaceuticals Hold...
48.51%
139.70 M
$ 7.54
United States
Healthcare
50
NEOV
NeoVolta Inc.
47.79%
115.30 M
$ 2.1
United States
Industrials
51
ABEO
Abeona Therapeutics Inc.
47.42%
324.30 M
$ 5.69
United States
Healthcare
52
CMP
Compass Minerals Internatio...
47.37%
1.40 B
$ 33.32
United States
Basic Materials
53
EDIT
Editas Medicine, Inc.
46.02%
432.76 M
$ 2.82
United States
Healthcare
54
AVR
Anteris Technologies Global...
45.59%
904.31 M
$ 9.29
Australia
Healthcare
55
EVLV
Evolv Technologies Holdings...
44.88%
1.21 B
$ 6.73
United States
Industrials
56
YALA
Yalla Group Limited
43.9%
857.83 M
$ 5.65
United Arab Emirates
Technology
57
POWW
Outdoor Holding Company
43.8%
241.61 M
$ 2.06
United States
Industrials
58
CNTB
Connect Biopharma Holdings ...
43.59%
135.37 M
$ 2.15
United States
Healthcare
59
SEZL
Sezzle Inc.
42.96%
3.98 B
$ 118.43
United States
Financial Services
60
UAMY
United States Antimony Corp...
42.67%
1.51 B
$ 10.19
United States
Basic Materials
61
CMPS
COMPASS Pathways plc
42.65%
1.80 B
$ 13.33
United Kingdom
Healthcare
62
SLP
Simulations Plus, Inc.
42.53%
338.85 M
$ 16.77
United States
Healthcare
63
MGNX
MacroGenics, Inc.
42.21%
257.43 M
$ 4.05
United States
Healthcare
64
SLS
SELLAS Life Sciences Group,...
42.2%
1.64 B
$ 8.33
United States
Healthcare
65
RGNX
REGENXBIO Inc.
42.16%
337.07 M
$ 6.52
United States
Healthcare
66
NG
NovaGold Resources Inc.
41.95%
3.68 B
$ 8.38
Canada
Basic Materials
67
CTGO
Contango Silver & Gold Inc.
41.31%
606.50 M
$ 19.71
United States
Basic Materials
68
HCSG
Healthcare Services Group, ...
41.11%
1.39 B
$ 20.24
United States
Healthcare
69
WW
WW International, Inc.
40.92%
159.78 M
$ 15.98
United States
Healthcare
70
CERT
Certara, Inc.
40.43%
874.27 M
$ 5.62
United States
Healthcare
71
IMNM
Immunome, Inc.
40.42%
2.19 B
$ 19.34
United States
Healthcare
72
HLVX
HilleVax, Inc.
40.07%
104.76 M
$ 2.09
United States
Healthcare
73
PLTR
Palantir Technologies Inc.
39.87%
364.80 B
$ 152.17
United States
Technology
74
FULC
Fulcrum Therapeutics, Inc.
39.49%
209.23 M
$ 3.14
United States
Healthcare
75
DBVT
DBV Technologies S.A.
39.47%
1.08 B
$ 18.23
France
Healthcare
76
SEPN
Septerna, Inc.
38.65%
1.35 B
$ 29.94
United States
Healthcare
77
ITRG
Integra Resources Corp.
38.52%
523.83 M
$ 2.59
Canada
Basic Materials
78
UPB
Upstream Bio, Inc.
38.21%
394.54 M
$ 7.25
United States
Healthcare
79
SABS
SAB Biotherapeutics, Inc.
38.19%
266.10 M
$ 3.48
United States
Healthcare
80
NUKKW
T3 Defense Inc.
37.52%
1.41 B
$ 0.1284
United States
81
GRAL
GRAIL, Inc.
37.43%
2.57 B
$ 59.9
United States
Healthcare
82
SLSR
Solaris Resources Inc.
37.35%
1.84 B
$ 10.99
Switzerland
Basic Materials
83
VERV
Verve Therapeutics, Inc.
37.12%
994.04 M
$ 11.13
United States
Healthcare
84
PPTA
Perpetua Resources Corp.
36.9%
3.27 B
$ 26.18
United States
Basic Materials
85
ARVN
Arvinas, Inc.
36.84%
516.17 M
$ 8
United States
Healthcare
86
SVV
Savers Value Village, Inc.
36.61%
1.37 B
$ 8.9
United States
Consumer Cyclical
87
ODD
Oddity Tech Ltd.
36.47%
565.20 M
$ 9.84
Israel
Consumer Defensive
88
MTC
MMTec, Inc.
36.36%
483.00 M
$ 4.85
Hong Kong
Technology
89
IDYA
IDEAYA Biosciences, Inc.
36.29%
2.45 B
$ 27.87
United States
Healthcare
90
SDGR
Schrödinger, Inc.
36.04%
1.12 B
$ 14.94
United States
Healthcare
91
ARCT
Arcturus Therapeutics Holdi...
35.84%
217.44 M
$ 7.65
United States
Healthcare
92
KYMR
Kymera Therapeutics, Inc.
35.8%
5.86 B
$ 71.29
United States
Healthcare
93
LFMD
LifeMD, Inc.
35.54%
226.82 M
$ 4.69
United States
Healthcare
94
DNLI
Denali Therapeutics Inc.
35.48%
3.07 B
$ 19.35
United States
Healthcare
95
CGC
Canopy Growth Corporation
35.29%
476.03 M
$ 1.06
Canada
Healthcare
96
THAR
Canton Strategic Holdings Inc
35.16%
187.37 M
$ 4.74
United States
Healthcare
97
EYPT
EyePoint, Inc.
35.05%
1.05 B
$ 12.53
United States
Healthcare
98
RLAY
Relay Therapeutics, Inc.
34.82%
3.42 B
$ 15.7
United States
Healthcare
99
DSGN
Design Therapeutics, Inc.
34.81%
635.19 M
$ 10.17
United States
Healthcare
100
TMDX
TransMedics Group, Inc.
34.77%
2.37 B
$ 68.45
United States
Healthcare
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q Which stock has gained the most in April 2025?
A

CEP (Cantor Equity Partners, Inc. Class A Ordinary Shares) has the highest monthly gain in this ranking for April 2025, with a gain of 292%. Top performers this month include CEP, PNBK, AREC.

Q What stocks gained the most in April 2025?
A

The biggest gainers in April 2025 were: CEP (+292%), PNBK (+240%), AREC (+123%), RGC (+107%), THTX (+103%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during April 2025. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during April 2025. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which sectors performed best in April 2025?
A

The top performing sectors in April 2025 included Financial Services, Basic Materials, Healthcare, based on the stocks with highest monthly gains. CEP led the Financial Services sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in April 2025. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner which tracks live intraday market activity across NYSE and NASDAQ.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.