Indicate by check mark whether the registrant
files or will file annual reports under cover of Form 20-F or Form 40-F.
On March 24, 2026, CollPlant Biotechnologies Ltd.
issued a press release entitled “CollPlant Biotechnologies Reports 2025 Financial Results and Provides Corporate Update.”
A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.
Pursuant to the requirements
of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto
duly authorized.
Exhibit
99.1

COLLPLANT BIOTECHNOLOGIES REPORTS 2025 FINANCIAL
RESULTS AND PROVIDES CORPORATE UPDATE
REHOVOT, Israel, March 26, 2026 -- CollPlant
Biotechnologies (Nasdaq: CLGN), a regenerative and aesthetics medicine company developing innovative technologies and products based on
its non-animal-derived rhCollagen for tissue regeneration and medical aesthetics, today announced its 2025 financial results and provided
a corporate update.
“Over the past year, we have made meaningful
progress across all fronts-from advancing our collaborative programs to building momentum in our proprietary pipeline and commercial product
portfolio. In aesthetic medicine, we achieved a development milestone that triggered a $2 million payment from our collaboration partner,
AbbVie. We also expanded our commercial reach by broadening our distribution footprint into North America through a new partnership with
a U.S.-based logistics center, while strengthening the European distribution network for our commercial product, Vergenix STR.
We further strengthened our pipeline by leveraging
new preclinical data to refine the commercial design of our regenerative breast implants. In addition, we expanded our intellectual property
portfolio with newly granted patents in the United States and South Korea covering our photocurable dermal filler technology.
CollPlant also continued to drive innovation beyond
its core development programs. Using our rhCollagen, researchers at Mayo Clinic created the first fully humanized 3D bioprinted skin model
designed to serve as an alternative to animal testing in preclinical research. In parallel, we reported results from a comparative study
demonstrating that CollPlant’s rhCollagen-based bioink, Collink.3D™, outperformed Matrigel®, a leading extracellular matrix,
in supporting structured tissue formation. We believe these findings reinforce the potential of Collink.3D™ as a consistent, tunable,
and animal-free alternative for advanced tissue engineering and research applications-an opportunity representing an approximately $100
million market that is projected to grow at more than 10% annually.

Mr. Tal added, “These achievements collectively
highlight how our rhCollagen platform enables animal-free solutions across healthcare and industry. Its applications range from drug discovery
and regenerative medicine to advanced tissue modeling and safety testing for cosmetics and pharmaceutical products.”
2025 and Recent Corporate Updates
rhCollagen 3D Bioprinting Portfolio
In February 2026, CollPlant announced the launch
of BioFlex, a ready-to-print rhCollagen-based kit designed for Digital Light Processing (DLP) 3D bioprinting applications. BioFlex
is engineered to support the biofabrication of advanced tissue models for drug discovery, as well as the development of engineered tissues
and potentially transplantable organs. The ready-to-use system includes Collink.3D™ 50, a biodegradable polymer component,
together with proprietary photoactive agents optimized for high-resolution DLP printing.
Designed for both academic laboratories and industrial
R&D environments, BioFlex enables advanced applications in 3D bioprinting, tissue engineering, and regenerative medicine, helping
accelerate the translation of research concepts into functional tissue constructs.
In October 2025, CollPlant announced that a scientific
article published in Archives of Dermatological Research reported that researchers at the Mayo Clinic developed the first fully
humanized 3D bioprinted skin model using CollPlant’s plant-derived rhCollagen. By combining rhCollagen with key human skin cell
types, the model provides an innovative, sustainable, and ethical alternative to animal testing in preclinical research, with potential
applications in cosmetic and pharmaceutical testing, disease modeling, and drug development.
Also in October 2025, CollPlant announced the
expansion of its distribution footprint into North America through a new partnership with a U.S.-based logistics center. The logistics
hub provides full cGMP-compliant storage and distribution services and will serve as a clinical supply depot. This expansion is expected
to support CollPlant’s growing customer base for its rhCollagen and BioInk product lines across the United States and Canada.
AbbVie Collaboration
Under CollPlant’s existing development and commercialization
agreement with development partner, AbbVie, CollPlant has granted AbbVie a worldwide exclusive license to use CollPlant’s rhCollagen technology
in combination with AbbVie’s proprietary technologies for the development and commercialization of dermal and soft tissue fillers. AbbVie
is conducting a review of interim results from the first cohort of patients enrolled under the clinical trials initiated in 2023.
Next steps for the program are to be determined by AbbVie upon concluding their assessment.

In February 2025, following a development achievement,
CollPlant received a $2 million payment from AbbVie, according to the development and commercialization agreement.
Regenerative Breast Implants
In August 2024, CollPlant initiated a preclinical
study evaluating its 200cc clinical-sized regenerative breast implants, which were manufactured with enhanced durability. The surgical
protocol was refined to enable implantation through a small incision while minimizing the risk of implant displacement or inversion. Analysis
of MRI and ultrasound imaging conducted in 2025 confirmed tissue integration and vascularization, providing valuable diagnostic insights
for future clinical applications. At six months post-implantation, one study arm demonstrated promising outcomes, with the implant showing
vascularization and rapid tissue ingrowth throughout the clinical-sized implant. No complications, including capsule formation, calcifications,
or local tissue reactions, were observed. In addition, implant volume retention and mechanical properties were maintained in the successful
study arm.
Following completion of this study phase, CollPlant
plans to further optimize the regenerative breast implants to support long-term durability and remodeling of the newly vascularized tissue.
Mr. Tal added, “CollPlant’s breast
implants currently under development represent a paradigm-shifting approach, designed not only to regenerate breast tissue but also to
offer inherent safety advantages. Following upgrades to our bioprinting process and related manufacturing capabilities, we have been able
to produce and test commercial-sized implants. We are encouraged by the results observed to date. This program represents one of our lead
development initiatives and has the potential to position CollPlant at the forefront of regenerative medicine.”
In the United States alone, hundreds of thousands
of patients each year experience complications associated with breast implants, ranging from autoimmune-related symptoms to the rare
but serious condition of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). CollPlant’s breast implants, composed
of the Company’s proprietary plant-derived rhCollagen and additional biomaterials, are designed to support the regeneration of
breast tissue without eliciting an immune response. As such, they may offer a transformative alternative for both aesthetic and reconstructive
procedures, including post-mastectomy breast reconstruction for cancer patients.

Intellectual Property
Photocurable Dermal Filler Product Candidate
In February 2025, CollPlant announced that it
had been granted U.S. Patent No. 12,186,449 related to its photocurable dermal filler product candidate. The patent covers polymerizable
solutions comprised of modified rhCollagen and additional components such as hyaluronic acid and is expected to remain in force until
2039.
More recently, CollPlant announced that the Korean
Patent Office has allowed a patent application covering key aspects of the Company’s photocurable dermal filler technology currently
under development for the aesthetic medicine market. South Korea represents one of the largest target markets for CollPlant’s photocurable
dermal filler product candidate.
rhCollagen Curable BioInk Product Portfolio
In November 2025, CollPlant announced that the
Japan Patent Office (JPO) granted a second patent under Patent Application No. 2023-101072, securing intellectual property protection
in Japan for CollPlant’s portfolio of rhCollagen-based curable BioInks through 2038.
The newly granted patent relates to CollPlant’s
innovative curable Collink.3D® BioInk product pipeline, which represents the first and only line of human collagen BioInk products
based on chemically modified plant-derived rhCollagen that can be mass produced with high purity and consistency. Collink.3D enables scalable
and reproducible biofabrication of tissue models, tissues, and potentially organ transplants, while closely mimicking the native properties
of biological tissues. In addition, these BioInks are animal-free, exhibit optimal rheological properties at room temperature, support
high cell viability across multiple cell types, and are biocompatible and non-immunogenic.
“These patent allowances and grants represent
important milestones in executing our strategy to expand the clinical and commercial applications of our rhCollagen platform into high-value
aesthetic and regenerative medicine markets,” said Yehiel Tal, Chief Executive Officer of CollPlant. “The United States and
South Korea are strategically important markets in aesthetic medicine, and strengthening our intellectual property position in these regions
further enhances the long-term value of our technology.”

Cost Reductions and Program Prioritization
In November 2025, CollPlant updated its expense
forecast and implemented a cost-reduction and workforce optimization plan. As part of this initiative, the Company adjusted its resource
allocation and reduced its workforce by approximately 25%.
Redesigned Corporate Website
In March 2026 CollPlant announced the launch
of its redesigned corporate website at www.collplant.com.
The new website provides expanded information
regarding the Company’s technology platform, product pipeline, strategic collaborations and corporate governance, and is intended to enhance
transparency and accessibility for investors, partners, and other stakeholders.
Year-Ended December 31, 2025 Financial Results
GAAP revenues for the year ended December 31,
2025, were $2.4 million compared to $515,000 for the year ended December 31, 2024. The increase in revenues is mainly attributable to
a development milestone achievement relating to the dermal filler product candidate, which triggered a $2 million payment from AbbVie
to CollPlant according to the AbbVie Development Agreement.
GAAP cost of revenues for the year ended December
31, 2025, was $835,000, compared to $1.6 million for the year ended December 31, 2024. The decrease in cost of revenues in the amount
of $790,000 is mainly comprised of (i) a $537,000 decrease in inventory impairments, (ii) a $228,000 decrease relating to bioinks and
rhCollagen sales, and (iii) a $90,000 insurance reimbursement received in 2025.
GAAP gross profit for the year ended December
31, 2025, was $1.5 million, compared to $1.1 million gross loss for the year ended December 31, 2024.

GAAP operating expenses for the year ended December
31, 2025, were $13.0 million, compared to $16.1 million for the year ended December 31, 2024. The decrease of approximately $3.1 million
is mainly as a result of the Company’s cost reduction plan, that includes: (i) a $1.5 million decrease in the workforce expenses
and share-based compensation expenses, (ii) a $1.1 million decrease in research and development materials and subcontractors expenses
mainly related to the breast implants program, and (iii) a decrease of $145,000 in patents expenses. On a non-GAAP basis, operating expenses
for the year ended December 31, 2025, were $12.1 million, compared to $14.4 million in the year ended December 31, 2024.
GAAP financial expenses, net, for the year ended
December 31, 2025, totaled $6,000, compared to $642,000 financial income, net, for the year ended December 31, 2024. The increase in financial
expenses, net is due to (i) a decrease of $358,000 in interest received from our short-term cash deposits, and (ii) an increase of approximately
$292,000 in exchange rate differences expenses.
GAAP net loss for the year ended December 31,
2025, was $11.5 million, or $0.94 basic loss per share, compared to net loss of $ $16.6 million, or $1.45 basic loss per share, for the
year ended December 31, 2024. Non-GAAP net loss for the year ended December 31, 2025, was $10.2 million, or $0.83 loss per share, compared
to a net loss of $14.9 million, or $1.3 basic loss per share, for the year ended December 31, 2024.
Balance Sheet and Cash Flow
The Company’s cash and cash equivalents
balance as of December 31, 2025 was $5.6 million.
Cash used in operating activities during the year
ended December 31, 2025 was $9.4 million compared to $14.1 million during the year ended December 31, 2024.
Cash used in investing activities during the year
ended December 31, 2025, was $27,000 compared to $539,000 during the year ended December 31, 2024, and related primarily to a decrease
in purchases of property and equipment.
Cash provided by financing activities during the
year ended December 31, 2025 was $3.1 million compared to $9,000 during the year ended December 31, 2024. The increase is mainly attributed
to our registered direct offering in June 2025, which resulted in net proceeds of $3.1 million.

COLLPLANT BIOTECHNOLOGIES LTD.
CONSOLIDATED BALANCE SHEETS
(U.S. dollars in thousands)
| | |
December 31, | |
| | |
2025 | | |
2024 | |
| Assets | |
| | |
| |
| Current assets: | |
| | |
| |
| Cash and cash equivalents | |
$ | 5,591 | | |
$ | 11,909 | |
| Restricted deposit | |
| 359 | | |
| 248 | |
| Trade receivables, net | |
| 1 | | |
| 150 | |
| Inventories | |
| 573 | | |
| 440 | |
| Other accounts receivable and prepaid expenses | |
| 223 | | |
| 433 | |
| Total current assets | |
| 6,747 | | |
| 13,180 | |
| Non-current assets: | |
| | | |
| | |
| Restricted deposit | |
| 76 | | |
| 118 | |
| Operating lease right-of-use assets | |
| 2,426 | | |
| 2,991 | |
| Property and equipment, net | |
| 1,463 | | |
| 2,290 | |
| Intangible assets, net | |
| 73 | | |
| 131 | |
| Total non-current assets | |
| 4,038 | | |
| 5,530 | |
| Total assets | |
$ | 10,785 | | |
$ | 18,710 | |

COLLPLANT BIOTECHNOLOGIES LTD.
CONSOLIDATED BALANCE SHEETS
(U.S. dollars in thousands, except share data)
| | |
December 31, | |
| | |
2025 | | |
2024 | |
| Liabilities and shareholders’ equity | |
| | |
| |
| Current liabilities: | |
| | |
| |
| Trade payables | |
$ | 610 | | |
$ | 870 | |
| Operating lease liabilities | |
| 814 | | |
| 806 | |
| Accrued liabilities and other payables | |
| 1,248 | | |
| 1,294 | |
| Total current liabilities | |
| 2,672 | | |
| 2,970 | |
| Non-current liabilities: | |
| | | |
| | |
| Operating lease liabilities | |
| 2,032 | | |
| 2,275 | |
| Total non-current liabilities | |
| 2,032 | | |
| 2,275 | |
| Total liabilities | |
| 4,704 | | |
| 5,245 | |
| | |
| | | |
| | |
| Commitments and contingencies | |
| | | |
| | |
| | |
| | | |
| | |
| Shareholders’ Equity: | |
| | | |
| | |
| Ordinary shares, NIS 1.5 par value - authorized: 30,000,000 ordinary shares as of December 31, 2025 and 2024; issued and outstanding: 12,803,006 and 11,454,512 ordinary shares as of December 31, 2025 and 2024, respectively | |
| 5,492 | | |
| 4,983 | |
| Additional paid in capital | |
| 126,397 | | |
| 122,801 | |
| Accumulated other comprehensive loss | |
| (969 | ) | |
| (969 | ) |
| Accumulated deficit | |
| (124,839 | ) | |
| (113,350 | ) |
| Total shareholders’ equity | |
| 6,081 | | |
| 13,465 | |
| Total liabilities and shareholders’ equity | |
$ | 10,785 | | |
$ | 18,710 | |

COLLPLANT BIOTECHNOLOGIES LTD.
CONSOLIDATED STATEMENTS OF OPERATIONS
(U.S. dollars in thousands, except share and per share data)
| | |
Year ended December 31, | |
| | |
2025 | | |
2024 | | |
2023 | |
| Revenues | |
$ | 2,371 | | |
$ | 515 | | |
$ | 10,959 | |
| Cost of revenues | |
| 835 | | |
| 1,625 | | |
| 1,991 | |
| Gross profit (loss) | |
| 1,536 | | |
| (1,110 | ) | |
| 8,968 | |
| | |
| | | |
| | | |
| | |
| Operating expenses: | |
| | | |
| | | |
| | |
| Research and development | |
| 8,187 | | |
| 10,515 | | |
| 10,484 | |
| General, administrative and marketing | |
| 4,832 | | |
| 5,626 | | |
| 5,996 | |
| Total operating loss | |
| (11,483 | ) | |
| (17,251 | ) | |
| (7,512 | ) |
| Financial income (expenses), net | |
| (6 | ) | |
| 642 | | |
| 493 | |
| Net loss | |
$ | (11,489 | ) | |
$ | (16,609 | ) | |
$ | (7,019 | ) |
| Basic and diluted net loss per ordinary share | |
$ | (0.94 | ) | |
$ | (1.45 | ) | |
$ | (0.62 | ) |
| Weighted average number of ordinary shares used in computation of basic and diluted net loss per share | |
| 12,203,269 | | |
| 11,454,180 | | |
| 11,389,168 | |

COLLPLANT BIOTECHNOLOGIES LTD.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(U.S. dollars in thousands)
| | |
Year ended December 31, | |
| | |
2025 | | |
2024 | | |
2023 | |
| Cash flows from operating activities: | |
| | |
| | |
| |
| Net loss | |
$ | (11,489 | ) | |
$ | (16,609 | ) | |
$ | (7,019 | ) |
| Adjustments to reconcile net loss to net cash used in operating activities: | |
| | | |
| | | |
| | |
| Loss on sale of property and equipment | |
| - | | |
| - | | |
| 18 | |
| Depreciation and amortization | |
| 912 | | |
| 1,038 | | |
| 1,102 | |
| Accrued interest | |
| (15 | ) | |
| (11 | ) | |
| (28 | ) |
| Share-based compensation to employees and consultants | |
| 999 | | |
| 1,719 | | |
| 1,937 | |
| Exchange differences on cash and cash equivalents and restricted cash | |
| (80 | ) | |
| 142 | | |
| 379 | |
| | |
| | | |
| | | |
| | |
| Changes in assets and liabilities: | |
| | | |
| | | |
| | |
| Decrease (increase) in trade receivables | |
| 149 | | |
| (150 | ) | |
| 9 | |
| Decrease (increase) in inventories | |
| (129 | ) | |
| 280 | | |
| 749 | |
| Decrease (increase) in other receivables and prepaid expenses | |
| 210 | | |
| (40 | ) | |
| 150 | |
| Decrease in operating lease right-of-use assets | |
| 666 | | |
| 651 | | |
| 527 | |
| Decrease in trade payables | |
| (260 | ) | |
| (110 | ) | |
| (153 | ) |
| Decrease in operating lease liabilities | |
| (336 | ) | |
| (650 | ) | |
| (638 | ) |
| Increase in accrued liabilities and other payables | |
| (46 | ) | |
| (353 | ) | |
| 204 | |
| Net cash used in operating activities | |
| (9,419 | ) | |
| (14,093 | ) | |
| (2,763 | ) |
| Cash flows from investing activities: | |
| | | |
| | | |
| | |
| Purchase of property and equipment | |
| (28 | ) | |
| (483 | ) | |
| (954 | ) |
| Investment in restricted deposits | |
| - | | |
| (57 | ) | |
| (270 | |
| Proceeds from sale of property and equipment | |
| 1 | | |
| 1 | | |
| 68 | |
| Net cash used in investing activities | |
| (27 | ) | |
| (539 | ) | |
| (1,156 | ) |
| Cash flows from financing activities: | |
| | | |
| | | |
| | |
| Proceeds from issuance of shares and warrants less issuance expenses | |
| 3,102 | | |
| - | | |
| - | |
| Exercise of options and warrants into shares | |
| - | | |
| 9 | | |
| 1,108 | |
| Net cash provided by financing activities | |
| 3,102 | | |
| 9 | | |
| 1,108 | |
| Effect of exchange rate changes on cash and cash equivalents and restricted cash | |
| 26 | | |
| (142 | ) | |
| (379 | ) |
| Net decrease in cash and cash equivalents | |
| (6,318 | ) | |
| (14,765 | ) | |
| (3,190 | ) |
| Cash and cash equivalents at the beginning of the year | |
| 11,909 | | |
| 26,674 | | |
| 29,864 | |
| | |
| | | |
| | | |
| | |
| Cash and cash equivalents at the end of the year | |
$ | 5,591 | | |
$ | 11,909 | | |
$ | 26,674 | |

COLLPLANT BIOTECHNOLOGIES LTD.
APPENDICES TO CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(U.S. dollars in thousands)
| | |
Year ended December 31, | |
| | |
2025 | | |
2024 | | |
2023 | |
| Supplemental discloser of non-cash activities: | |
| | |
| | |
| |
| | |
| | |
| | |
| |
| Right of use assets recognized with corresponding lease liabilities | |
$ | 101 | | |
$ | 572 | | |
$ | 886 | |
| Capitalization of Share-based compensation to inventory | |
$ | 4 | | |
$ | 6 | | |
$ | 33 | |
| | |
| | | |
| | | |
| | |
| Supplemental discloser of cash activities: | |
| | | |
| | | |
| | |
| | |
| | | |
| | | |
| | |
| Cash paid during the year for taxes | |
$ | 16 | | |
$ | 62 | | |
$ | 8 | |

COLLPLANT BIOTECHNOLOGIES LTD.
RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL
MEASURES
(U.S. dollars in thousands, except per share data)
| | |
Year ended December 31, | |
| | |
2025 | | |
2024 | |
| | |
| | |
| |
| GAAP operating expenses: | |
$ | 13,019 | | |
$ | 16,141 | |
| | |
| | | |
| | |
| Change of operating lease accounts | |
| 50 | | |
| (18 | ) |
| Share-based compensation to employees, directors and consultants | |
| (999 | ) | |
| (1,719 | ) |
| Non-GAAP operating expenses: | |
| 12,070 | | |
| 14,404 | |
| | |
| | | |
| | |
| GAAP operating loss | |
| (11,483 | ) | |
| (17,251 | ) |
| Change of operating lease accounts | |
| (50 | ) | |
| 18 | |
| Share-based compensation to employees, directors and consultants | |
| 999 | | |
| 1,719 | |
| Non-GAAP operating loss | |
| (10,534 | ) | |
| (15,514 | ) |
| | |
| | | |
| | |
| GAAP Net loss | |
| (11,489 | ) | |
| (16,609 | ) |
| Change of operating lease accounts | |
| 330 | | |
| 1 | |
| Share-based compensation to employees, directors and consultants | |
| 999 | | |
| 1,719 | |
| Non-GAAP Net loss | |
$ | (10,160 | ) | |
$ | (14,889 | ) |
| GAAP basic and diluted loss per ordinary share | |
$ | (0.94 | ) | |
$ | (1.45 | ) |
| NON- GAAP basic and diluted loss per ordinary share | |
$ | (0.83 | ) | |
$ | (1.30 | ) |

About CollPlant
CollPlant is a regenerative and aesthetic medicine
company focused on 3D bioprinting of tissues and organs, and medical aesthetics. The Company’s products are based on its rhCollagen
(recombinant human collagen) produced with CollPlant’s proprietary plant-based genetic engineering technology. These products address
indications for the diverse fields of tissue repair, aesthetics, and organ manufacturing, and are ushering in a new era in regenerative
and aesthetic medicine.
In 2021, CollPlant entered into a development
and global commercialization agreement for dermal and soft tissue fillers with Allergan, an AbbVie company, the global leader in the dermal
filler market.
For more information about CollPlant, visit http://www.collplant.com.
Use of Non-US GAAP (“non-GAAP”)
Financial results for 2025 and 2024 are presented
on both a GAAP and a non-GAAP basis. GAAP results were prepared in accordance with U.S. GAAP and include all revenue and expenses recognized
during the period. The release contains certain non-GAAP financial measures for operating costs and expenses, operating income (or loss),
net income (or loss) and basic and diluted net income (or loss) per share that exclude the effects of non-cash expense for share-based
compensation to employees, directors and consultants, and change in operating lease accounts. CollPlant’s management believes that
these non-GAAP financial measures provide meaningful supplemental information regarding the Company’s performance that enhances
management’s and investors’ ability to evaluate the Company’s operating costs, net income (or loss) and income (or loss)
per share, and to compare them to historical Company results.
The presentation of this non-GAAP financial information
is not intended to be considered in isolation or as a substitute for the financial information prepared and presented in accordance with
GAAP. Management uses both GAAP and non-GAAP measures when operating and evaluating the Company’s business internally and therefore
decided to make these non-GAAP adjustments available to investors. The non-GAAP financial measures used by the Company in this press release
may be different from the measures used by other companies.
For more information on the non-GAAP financial
measures, please see the “Reconciliation of GAAP to Non-GAAP Financial Measures” in this release. This accompanying table
has more details on the GAAP financial measures that are most directly comparable to non-GAAP financial measures and the related reconciliations
between these financial measures.
The Company’s consolidated financial statements
for the year ended December 31, 2025, are presented in accordance with generally accepted accounting principles in the U.S.
A copy of the Company’s annual report on Form 20-F for the year
ended December 31, 2025 has been filed with the U.S. Securities and Exchange Commission at www.sec.gov and posted on the Company’s
investor relations website at http://ir.collplant.com/. The Company will deliver a hard copy of its annual report, including its complete
audited consolidated financial statements, free of charge, to its shareholders upon request to CollPlant Investor Relations at 4 Oppenheimer,
Weizmann Science Park, Rehovot 767104, Israel or by phone at +972-73-232 5600.

Forward-Looking Statements
This press release may include
forward-looking statements. Forward-looking statements may include, but are not limited to, statements relating to CollPlant’s
objectives plans and strategies, as well as statements, other than historical facts, that address activities, events or developments
that CollPlant intends, expects, projects, believes or anticipates will or may occur in the future. These statements are often
characterized by terminology such as “believes,” “hopes,” “may,” “anticipates,”
“should,” “intends,” “plans,” “will,” “expects,”
“estimates,” “projects,” “positioned,” “strategy” and similar expressions and are
based on assumptions and assessments made in light of management’s experience and perception of historical trends, current
conditions, expected future developments and other factors believed to be appropriate. Forward-looking statements are not guarantees
of future performance and are subject to risks and uncertainties that could cause actual results to differ materially from those
expressed or implied in such statements. Many factors could cause CollPlant’s actual activities or results to differ
materially from the activities and results anticipated in forward-looking statements, including, but not limited to, the following:
the Company’s history of significant losses, its need to raise additional capital and its inability to obtain additional
capital on acceptable terms, or at all; the Company’s expectations regarding the costs and timing of commencing and/or
concluding pre-clinical and clinical trials with respect to breast implants, tissues and organs which are based on its rhCollagen
based BioInk and other products for medical aesthetics, and specifically the Company’s ability to initiate its next
large-animal study for its breast implants in a timely manner, or at all; the Company’s or it strategic partners’
ability to obtain favorable pre-clinical and clinical trial results; regulatory action with respect to rhCollagen based bioink and
medical aesthetics products or product candidates including, but not limited to acceptance of an application for marketing
authorization review and approval of such application, and, if approved, the scope of the approved indication and labeling;
commercial success and market acceptance of the Company’s rhCollagen based products, in 3D bioprinting and medical aesthetics;
the Company’s ability to establish sales and marketing capabilities or enter into agreements with third parties and its
reliance on third party distributors and resellers; the Company’s ability to establish and maintain strategic partnerships and
other corporate collaborations, including its partnership with AbbVie and its ability to continue to receive milestone and royalties
payments under the AbbVie agreement; the Company’s reliance on third parties to conduct some or all aspects of its product
development and manufacturing; the scope of protection the Company is able to establish and maintain for intellectual property
rights and the Company’s ability to operate its business without infringing the intellectual property rights of others;
current or future unfavorable economic and market conditions and adverse developments with respect to financial institutions and
associated liquidity risk; the impact of competition and new technologies; general market, political, and economic conditions in the
countries in which the Company operates, including, with respect to the ongoing war in Israel, projected capital expenditures and
liquidity, changes in the Company’s strategy, and litigation and regulatory proceedings. More detailed information about the
risks and uncertainties affecting CollPlant are contained under the heading “Risk Factors” included in CollPlant’s
most recent annual report on Form 20-F filed with the SEC, and in other filings that CollPlant has made and may make with the SEC in
the future. The forward-looking statements contained in this press release are made as of the date of this press release and reflect
CollPlant’s current views with respect to future events, and CollPlant does not undertake and specifically disclaims any
obligation to update or revise any forward-looking statements, whether as a result of new information, future events or
otherwise.
Contacts
CollPlant:
Eran Rotem
Deputy CEO & CFO
Tel: + 972-73-2325600
Email: Eran@collplant.com