[Form 4] Guardant Health, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Tariq Musa, a director of Guardant Health, reported two transactions in September 2025. On 09/15/2025 249 restricted stock units (RSUs) vested, converting into 249 common shares and increasing his derivative/underlying holdings. On 09/17/2025 he sold 116 common shares at $55.63 per share, reducing his direct common stock holdings from 7,707 to 7,591 shares. After these transactions, he beneficially owns 7,591 common shares directly and 4,498 shares underlying RSUs.

Positive

• 249 RSUs vested, converting into 249 common shares
• Sale price disclosed: $55.63 per share for the 116-share disposition
• Post-transaction holdings disclosed: direct ownership reported as 7,591 common shares and 4,498 shares underlying RSUs

Negative

• Director's direct common shares decreased from 7,707 to 7,591 after the sale
• Disposition of 116 shares reduced insider's direct stake

Insights

Financial Analyst

TL;DR: Small vesting event followed by a partial sale; modest net change in director's stake.

The filing shows a routine vesting of 249 RSUs that converted to common shares and a subsequent 116-share sale at $55.63. The director's direct common holdings decreased from 7,707 to 7,591. These transactions are transactional and not material relative to a typical public company market cap; they change share counts by low hundreds rather than large ownership blocks.

Corporate Governance Expert

TL;DR: Routine insider reporting of RSU vesting and a small disposition, consistent with normal director compensation liquidity events.

The Form 4 documents standard equity compensation mechanics: an RSU award vesting schedule produced 249 shares, and the director sold 116 shares. The filing is signed by an attorney-in-fact and includes the required explanatory note on the RSU vesting schedule. There are no indications in this filing of unusual governance issues or material related-party transactions.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Tariq Musa

(Last) (First) (Middle)

3100 HANOVER STREET

(Street)

PALO ALTO CA 94304

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Guardant Health, Inc. [ GH ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
09/15/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	09/15/2025		M		249	A	$0	7,707	D
Common Stock	09/17/2025		S		116	D	$55.63	7,591	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Restricted Stock Units	$0	09/15/2025		M			249	(1)	(2)	Common Stock	249	$0	4,498	D

Explanation of Responses:

1. The restricted stock unit award granted on March 6, 2023 vests over a four-year period. 25% of the shares subject to such award vested on the one-year anniversary of March 15, 2023. The remaining 75% vests monthly for the three-year period thereafter.

2. Not applicable for Restricted Stock Units.

Remarks:

	/s/ John G. Saia, as attorney-in-fact for Musa Tariq	09/17/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What transactions did Guardant Health (GH) director Tariq Musa report?

He reported that 249 RSUs vested on 09/15/2025 and that he sold 116 common shares on 09/17/2025 at $55.63 per share.

How many shares does Tariq Musa own after the September 2025 transactions?

After the transactions he beneficially owns 7,591 common shares directly and has 4,498 shares underlying RSUs.

What was the price of the sale reported on the Form 4 for GH?

The Form 4 lists a sale price of $55.63 per share for the 116-share disposition.

When did the RSU award that vested originate and how does it vest?

The RSU award was granted on March 6, 2023 and vests over four years with 25% on the one-year anniversary and the remaining 75% vesting monthly over the next three years.

Who signed the Form 4 filing for Tariq Musa?

The Form 4 was signed by John G. Saia as attorney-in-fact for Tariq Musa on 09/17/2025.