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Harrow, Inc. common stock is reported as beneficially owned by Opaleye Management Inc., Opaleye, L.P., and James Silverman. Opaleye, L.P. directly holds 2,105,000 shares, or 5.62% of the class. Opaleye Management, as the Fund's investment adviser, and Silverman, as the adviser's controlling person, may be deemed to beneficially own those same shares. The percentage is based on 37,487,850 shares outstanding as of August 6, 2026.
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.
shared voting powerregulatory
"Shared Voting Power 2,105,000"
Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.
shared dispositive powerregulatory
"Shared Dispositive Power 2,105,000"
Joint Filing Agreementregulatory
"Joint Filing Agreement by and among the reporting persons"
FAQ
AI-generated questions and answers. How Rhea-AI works. Not financial advice.
How many HROW shares does Opaleye report owning?
Opaleye, L.P. directly holds 2,105,000 HROW common shares. Opaleye Management Inc., its investment adviser, and James Silverman, the adviser's controlling person, may be deemed beneficial owners of those same shares.
What percentage of HROW does Opaleye report owning?
The reported position represents 5.62% of HROW's common stock, based on 37,487,850 shares outstanding as of August 6, 2026.
Who receives dividends and sale proceeds from the reported HROW shares?
Opaleye, L.P. is entitled to receive dividends from, and proceeds from the sale of, the reported shares. Its interest in these shares exceeds 5% of HROW's outstanding common stock.
Who has voting and disposition power over the HROW shares?
The reporting persons report shared voting power and shared power to dispose of or direct the disposition of all 2,105,000 shares. Each reports zero sole voting power and zero sole dispositive power.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 10)
Harrow, Inc.
(Name of Issuer)
Common Stock, $0.001 par value per share
(Title of Class of Securities)
415858109
(CUSIP Number)
09/30/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
415858109
1
Names of Reporting Persons
Opaleye Management Inc.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
MASSACHUSETTS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,105,000.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,105,000.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,105,000.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.62 %
12
Type of Reporting Person (See Instructions)
IA, CO
SCHEDULE 13G
CUSIP Number(s):
415858109
1
Names of Reporting Persons
Opaleye, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,105,000.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,105,000.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,105,000.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.62 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: Based on 37,487,850 shares of Common Stock outstanding as of August 6, 2026, as reported by Harrow, Inc. in its Form 10-Q filed with the SEC on August 10, 2026.
SCHEDULE 13G
CUSIP Number(s):
415858109
1
Names of Reporting Persons
James Silverman
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,105,000.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,105,000.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,105,000.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.62 %
12
Type of Reporting Person (See Instructions)
IN
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Harrow, Inc.
(b)
Address of issuer's principal executive offices:
1A Burton Hills Blvd., Suite 200, Nashville, TN 37215
Item 2.
(a)
Name of person filing:
This statement is filed by (i) Opaleye Management Inc. (the "Adviser"), (ii) Opaleye, L.P. (the "Fund"), and (iii) James Silverman (collectively, the "Reporting Persons"). The Fund directly holds 2,105,000 shares of Common Stock, par value $0.001 per share (the "Common Stock"), of Harrow, Inc. (the "Issuer"). The Adviser, as investment adviser to the Fund, and Mr. Silverman, as the controlling person of the Adviser, may be deemed to beneficially own the 2,105,000 shares of Common Stock held directly by the Fund. The filing of this statement shall not be construed as an admission that any Reporting Person is the beneficial owner of any securities covered by this statement for purposes of Section 13 of the Securities Exchange Act of 1934, as amended, or otherwise.
(b)
Address or principal business office or, if none, residence:
One Boston Place, 26th Floor, Boston, MA 02108
(c)
Citizenship:
Opaleye Management Inc. - Massachusetts Opaleye, L.P. - Delaware James Silverman - United States
(d)
Title of class of securities:
Common Stock, $0.001 par value per share
(e)
CUSIP No.:
415858109
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
2,105,000.00
(b)
Percent of class:
5.62 %
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
0
(ii) Shared power to vote or to direct the vote:
2,105,000.00
(iii) Sole power to dispose or to direct the disposition of:
0
(iv) Shared power to dispose or to direct the disposition of:
2,105,000.00
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
The Fund is entitled to receive dividends from, and the proceeds from the sale of, the shares reported herein. The Fund's interest exceeds 5% of the outstanding Common Stock.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Opaleye Management Inc.
Signature:
/s/ James Silverman
Name/Title:
President
Date:
11/06/2026
Opaleye, L.P.
Signature:
Opaleye GP LLC, its general partner /s/ James Silverman
Name/Title:
Managing Member
Date:
11/06/2026
James Silverman
Signature:
/s/ James Silverman
Name/Title:
Individually
Date:
11/06/2026
Exhibit Information
Exhibit 99.1 Joint Filing Agreement by and among the reporting persons
