[Form 4] Personalis, Inc. Insider Trading Activity

Personalis, Inc. director Karin Eastham received new equity awards.

Rhea-AI Filing Summary

Personalis, Inc. director Karin Eastham received new equity awards. She was granted 6,250 shares of common stock in the form of restricted stock units and 37,500 stock options with an exercise price of $6.04 per share.

Both the RSUs and options vest 100% on the earlier of the one-year anniversary of the May 12, 2026 grant date or the day before Personalis’ next annual stockholder meeting, subject to continuous service. They also fully vest immediately before a qualifying Change in Control. After these grants, she directly holds 22,366 common shares and 37,500 options.

Insider Trade Summary

Grant/Award: 43,750 shares

Grant/Award 2 txns

Insider EASTHAM KARIN

Role Director

Type	Security	Shares	Price	Value
Grant/Award	Stock Option (right to buy)	37,500	$0.00	$0.00
Grant/Award	Common Stock	6,250	$0.00	$0.00

Holdings After Transaction: Stock Option (right to buy) — 37,500 contracts (Direct); Common Stock — 22,366 shares (Direct)

Footnotes (2)

1. F1. Each share is represented by a restricted stock unit ("RSU"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement. 100% of the shares subject to the RSU shall vest on the earlier of the one-year anniversary of the grant date or the day prior to the Company's next annual meeting of stockholders occurring after the grant date, subject to the reporting person's Continuous Service (as defined in the Company's 2019 Equity Incentive Plan (the "2019 Plan")) through the vesting date. In the event of a Change in Control (as defined in the 2019 Plan), the shares underlying the RSU shall vest immediately prior to the effectiveness of such Change in Control.
2. F2. 100% of the shares subject to the option shall vest on the earlier of the one-year anniversary of the grant date or the day prior to the Company's next annual meeting of stockholders occurring after the grant date, subject to the reporting person's Continuous Service (as defined in the 2019 Plan) through the vesting date. In the event of a Change in Control (as defined in the 2019 Plan), the shares underlying the option shall vest and become exercisable immediately prior to the effectiveness of such Change in Control.

Key Figures

RSU grant size: 6,250 shares Option grant size: 37,500 options Option exercise price: $6.04 per share +5 more

8 metrics

RSU grant size 6,250 shares Restricted stock units granted to director on May 12, 2026

Option grant size 37,500 options Stock options granted to director on May 12, 2026

Option exercise price $6.04 per share Conversion or exercise price for 37,500 options

Option expiration May 12, 2036 Expiration date of stock option grant

Shares held after grant 22,366 shares Total common stock directly owned after RSU grant

Options held after grant 37,500 options Total stock options directly owned after transaction

RSU vesting condition 100% cliff vest Earlier of one year from grant or day before next annual meeting

Change in Control vesting Immediate vesting RSUs and options vest immediately before a qualifying Change in Control

Key Terms

restricted stock unit ("RSU"), Continuous Service, Change in Control, 2019 Equity Incentive Plan, +1 more

5 terms

restricted stock unit ("RSU") financial

"Each share is represented by a restricted stock unit ("RSU")."

Continuous Service financial

"subject to the reporting person's Continuous Service (as defined in the Company's 2019 Equity Incentive Plan"

Change in Control financial

"In the event of a Change in Control (as defined in the 2019 Plan), the shares underlying the RSU shall vest"

A "change in control" occurs when the ownership or management of a company shifts significantly, such as through a merger, acquisition, or sale of a large part of its assets. This change can impact how the company is run and may influence its future direction. For investors, it matters because it can affect the company's stability, strategy, and value, often signaling potential changes in investment risk or opportunity.

2019 Equity Incentive Plan financial

"as defined in the Company's 2019 Equity Incentive Plan (the "2019 Plan")"

Stock Option (right to buy) financial

"Stock Option (right to buy)"

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Accepted by SEC EDGAR 05/14/2026 - 05:09 PM EDT Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

EASTHAM KARIN

(Last) (First) (Middle)

C/O PERSONALIS, INC.

6600 DUMBARTON CIRCLE

(Street)

FREMONT CALIFORNIA 94555

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Personalis, Inc. [ PSNL ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
05/12/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	05/12/2026		A		6,250(1)	A	$0	22,366	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	$6.04	05/12/2026		A		37,500		(2)	05/12/2036	Common Stock	37,500	$0	37,500	D

Explanation of Responses:

1. Each share is represented by a restricted stock unit ("RSU"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement. 100% of the shares subject to the RSU shall vest on the earlier of the one-year anniversary of the grant date or the day prior to the Company's next annual meeting of stockholders occurring after the grant date, subject to the reporting person's Continuous Service (as defined in the Company's 2019 Equity Incentive Plan (the "2019 Plan")) through the vesting date. In the event of a Change in Control (as defined in the 2019 Plan), the shares underlying the RSU shall vest immediately prior to the effectiveness of such Change in Control.

2. 100% of the shares subject to the option shall vest on the earlier of the one-year anniversary of the grant date or the day prior to the Company's next annual meeting of stockholders occurring after the grant date, subject to the reporting person's Continuous Service (as defined in the 2019 Plan) through the vesting date. In the event of a Change in Control (as defined in the 2019 Plan), the shares underlying the option shall vest and become exercisable immediately prior to the effectiveness of such Change in Control.

	/s/ Aaron Tachibana, Attorney-in-Fact	05/14/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)