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Zenas BioPharma Inc. Financials

ZBIO
FY2025 annual
Revenue $10.0M +100.0% YoY
Net Income -$377.7M -140.6% YoY
EPS (Diluted) -$8.44 YoY not available
Free Cash Flow -$172.4M -43.9% YoY
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Zenas BioPharma Inc. (ZBIO) reported $10.0M in revenue for fiscal year 2025, up 100.0% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 3 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ZBIO FY2025

ZBIO remains a balance-sheet-funded development company, where research spending rather than customer revenue determines the business's cash needs.

In FY2025, operating cash flow and free cash flow were essentially the same at about -$172.3M because capex was only $18K, so cash use is coming from funding the development program rather than building a lasting asset base. That matters because cash fell from $319.7M to $110.6M across FY2024-FY2025 even after financing inflows, showing the company still operates mainly on external funding, not on customer receipts.

Revenue was only $10M in FY2025 while R&D reached $168.1M, which means year-to-year sales changes are still far less important than management's decision to keep expanding the development program.

Near-term liquidity looks comfortable with a current ratio of 5.6x, and cash still exceeded current liabilities. But the arrival of long-term debt at $78.6M means the funding mix is no longer just equity and cash reserves.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 32 / 100
Financial Health Score 32/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Zenas BioPharma Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
33
Dilution
5
R&D Intensity
74
Revenue Progress
4
Burn Trend
5
Balance Sheet
70
Altman Z-Score Safe
3.58

Zenas BioPharma Inc. scores 3.58, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($2.1B) relative to total liabilities ($141.5M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
2/7

Zenas BioPharma Inc. passes 2 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Zenas BioPharma Inc. reported a net loss of $377.7M while operations used $172.3M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Zenas BioPharma Inc. reported an operating loss of $383.1M against $7.3M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$10.0M
YoY+100.0%

Zenas BioPharma Inc. generated $10.0M in revenue in fiscal year 2025. This represents an increase of 100.0% from the prior year.

EBITDA
-$383.0M
YoY-133.9%

Zenas BioPharma Inc.'s EBITDA was -$383.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 133.9% from the prior year.

Net Income
-$377.7M
YoY-140.6%

Zenas BioPharma Inc. reported -$377.7M in net income in fiscal year 2025. This represents a decrease of 140.6% from the prior year.

EPS (Diluted)
-$8.44

Zenas BioPharma Inc. earned -$8.44 per diluted share (EPS) in fiscal year 2025.

Cash & Balance Sheet

Free Cash Flow
-$172.4M
YoY-43.9%

Zenas BioPharma Inc. recorded an outflow of $172.4M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents a decrease of 43.9% from the prior year.

Cash & Debt
$110.6M
YoY-65.4%

Zenas BioPharma Inc. held $110.6M in cash against $78.6M in long-term debt as of fiscal year 2025.

Shares Outstanding
54M

Zenas BioPharma Inc. had 54M shares outstanding in fiscal year 2025.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Return on Equity
-156.0%
YoY-105.8pp

Zenas BioPharma Inc.'s ROE was -156.0% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 105.8 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$168.1M
YoY+20.8%

Zenas BioPharma Inc. invested $168.1M in research and development in fiscal year 2025. This represents an increase of 20.8% from the prior year.

Capital Expenditures
$18K
YoY-86.3%

Zenas BioPharma Inc. invested $18K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 86.3% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

ZBIO Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ZBIO annual income statement
MetricTTMFY25FY24FY23
RevenueN/A$10.0M+100.0%$5.0M-90.0%$50.0M
R&D ExpensesN/A$168.1M+20.8%$139.1M+131.8%$60.0M
SG&A ExpensesN/A$53.3M+79.2%$29.7M+73.8%$17.1M
Operating IncomeN/A-$383.1M-133.7%-$163.9M-341.2%-$37.1M
Interest ExpenseN/A$7.3MN/AN/A
Income TaxN/A-$79K-118.4%$429K+42.5%$301K
Net IncomeN/A-$377.7M-140.6%-$157.0M-322.9%-$37.1M
EPS (Diluted)-$8.44-$11.89-$24.25

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

ZBIO Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ZBIO annual balance sheet
MetricFY25FY24FY23
Total Assets$383.6M+3.7%$370.0M+442.6%$68.2M
Current Assets$351.2M-1.3%$355.9M+495.1%$59.8M
Cash & Equivalents$110.6M-65.4%$319.7M+462.4%$56.9M
Total Liabilities$141.5M+146.0%$57.5M-80.4%$293.9M
Current Liabilities$62.6M+9.4%$57.3M+146.3%$23.3M
Long-Term Debt$78.6MN/AN/A
Total Equity$242.1M-22.5%$312.5M+238.4%-$225.7M
Retained Earnings-$765.1M-97.5%-$387.4M-68.1%-$230.4M

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill.

ZBIO Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ZBIO annual cash flow statement
MetricTTMFY25FY24FY23
Operating Cash Flow-$226.0M-$172.3M-44.0%-$119.7M-292.0%-$30.5M
Capital Expenditures$2K$18K-86.3%$131K+670.6%$17K
Free Cash Flow-$226.0M-$172.4M-43.9%-$119.8M-292.2%-$30.5M
Investing Cash Flow-$309.4M-$251.9M-724.5%-$30.6M-179617.6%-$17K
Financing Cash Flow$689.0M$215.3M-47.9%$413.0M+1952.9%$20.1M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

ZBIO Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

ZBIO annual financial ratios
MetricFY25FY24FY23
Operating Margin-3830.6%-3277.8%-74.3%
Net Margin-3777.4%-3139.8%-74.3%
Return on Equity-156.0%-105.8pp-50.2%N/A
Return on Assets-98.5%-56.0pp-42.4%+12.0pp-54.4%
Current Ratio5.61-0.6x6.21+3.6x2.57
Debt-to-Equity0.32+0.1x0.18N/A
FCF Margin-1723.5%-2396.1%-61.1%

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Zenas BioPharma Inc.'s annual revenue?

Zenas BioPharma Inc. (ZBIO) reported $10.0M in total revenue for fiscal year 2025. This represents a 100.0% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Zenas BioPharma Inc.'s revenue growing?

Zenas BioPharma Inc. (ZBIO) revenue grew by 100.0% year-over-year, from $5.0M to $10.0M in fiscal year 2025.

Is Zenas BioPharma Inc. profitable?

No, Zenas BioPharma Inc. (ZBIO) reported a net income of -$377.7M in fiscal year 2025.

Zenas BioPharma Inc. (ZBIO) reported diluted earnings per share of -$8.44 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Zenas BioPharma Inc. (ZBIO) had EBITDA of -$383.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Zenas BioPharma Inc. (ZBIO) had $110.6M in cash and equivalents against $78.6M in long-term debt.

Zenas BioPharma Inc. (ZBIO) has a return on equity of -156.0% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Zenas BioPharma Inc. (ZBIO) recorded an outflow of $172.4M in free cash flow during fiscal year 2025. This represents a -43.9% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Zenas BioPharma Inc. (ZBIO) recorded an outflow of $172.3M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Zenas BioPharma Inc. (ZBIO) had $383.6M in total assets as of fiscal year 2025, including both current and long-term assets.

Zenas BioPharma Inc. (ZBIO) invested $18K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Zenas BioPharma Inc. (ZBIO) invested $168.1M in research and development during fiscal year 2025.

Zenas BioPharma Inc. (ZBIO) had 54M shares outstanding as of fiscal year 2025.

Zenas BioPharma Inc. (ZBIO) had a current ratio of 5.61 as of fiscal year 2025, which is generally considered healthy.

Zenas BioPharma Inc. (ZBIO) had a debt-to-equity ratio of 0.32 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Zenas BioPharma Inc. (ZBIO) had a return on assets of -98.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Zenas BioPharma Inc. (ZBIO) had $110.6M in cash against an annual operating cash burn of $172.3M. This gives an estimated cash runway of approximately 8 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Zenas BioPharma Inc. (ZBIO) has an Altman Z-Score of 3.58, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Zenas BioPharma Inc. (ZBIO) has a Piotroski F-Score of 2 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Zenas BioPharma Inc. (ZBIO) reported a net loss of $377.7M while operations used $172.3M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Zenas BioPharma Inc. (ZBIO) reported an operating loss of $383.1M against $7.3M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Zenas BioPharma Inc. (ZBIO) scores 32 out of 100 on our Financial Health Score, indicating weak standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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