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Calidi Biotherapeutics Announces $1.2 Million Registered Direct Offering

Calidi Biotherapeutics (CLDI) entered a definitive agreement for a registered direct offering of 1,025,640 common shares at $1.17 per share, with closing expected on or about September 18, 2026, subject to customary conditions.

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Calidi Biotherapeutics (CLDI) entered a definitive agreement for a registered direct offering of 1,025,640 common shares at $1.17 per share, with closing expected on or about September 18, 2026, subject to customary conditions.

The transaction is expected to generate approximately $1.2 million in gross proceeds before expenses. Calidi plans to use the net proceeds for working capital and general corporate purposes. The securities are being issued under an effective shelf registration statement on Form S-3, and the offering will be made using a prospectus and prospectus supplement to be filed with the SEC.

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Positive

  • Registered direct offering expected to raise approximately $1.2 million in gross proceeds
  • New capital earmarked for working capital and general corporate purposes
  • Financing conducted under an already effective Form S-3 shelf registration

Negative

  • Issuance of 1,025,640 new common shares may dilute existing shareholders

News Explained

The agreed sale remains unclosed, and its 1.2 million dollars of gross proceeds equal 25.1 days of second-quarter operating cash use.

Calidi has signed the agreement but has not yet closed the offering; if completed, issuing 1,025,640 new shares would increase the share count and reduce existing holders’ percentage ownership.

A registered direct is a negotiated sale to selected investors. The Form S-3 supplies shelf capacity rather than completing this sale, while the prospectus supplement carries the final terms for this takedown.

The $1.2 million gross amount equals 25.1 days of the last reported quarterly operating cash use, while $4.29 million of cash and equivalents at June 30, 2026 equals 89.7 days at that rate.

Sources and calculations
  • Offering gross against the last reported quarterly operating outflow, in days at that rate $1,200,000 / ($4,353,000 / 91) = 25.1 days
  • Available liquidity against the last reported quarterly operating outflow, in days at that rate $4,290,000 / ($4,353,000 / 91) = 89.7 days

Market Context

-53.14% was the 24-hour reaction after Calidi priced its March 6 underwritten offering, providing re...
Analysis

-53.14% was the 24-hour reaction after Calidi priced its March 6 underwritten offering, providing relevant financing precedent for this registered direct offering; the current pre-publication close was unchanged.

Key Figures

Shares offered: 1,025,640 shares Purchase price: $1.17 per share Gross proceeds: Approximately $1.2 million +2 more
Shares offered
1,025,640 shares
Registered direct offering
Purchase price
$1.17 per share
Registered direct offering
Gross proceeds
Approximately $1.2 million
Before offering expenses
Expected closing
September 18, 2026
Subject to customary closing conditions
Shelf effectiveness
October 10, 2024
Form S-3 registration statement declared effective

Previous Offering Reports

5 past events · Latest: Mar 09
Same Type 5 events
  1. Mar 09

    Offering closing

    24h Move
    -1.5%

    Closed a $6.0 million underwritten offering with shares and multiple warrant series

  2. Mar 06

    Offering pricing

    24h Move
    -53.1%

    Priced a $5.2 million underwritten offering with units and three warrant series

  3. Mar 05

    Offering proposal

    24h Move
    -53.1%

    Proposed an underwritten offering of units with accompanying common warrants

  4. Aug 21

    Offering closing

    24h Move
    +2.4%

    Closed a $6.9 million offering with common stock units and pre-funded warrants

  5. Aug 20

    Offering pricing

    24h Move
    -42.7%

    Priced a $6 million underwritten offering with common and pre-funded warrant units

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Key Terms

registered direct offering, accredited investors, qualified institutional buyers, shelf registration statement, +1 more
5 terms
registered direct offering financial
"for the purchase and sale of 1,025,640 shares of the Company’s common stock, in a registered direct offering"
A registered direct offering is a way for a company to sell new shares of its stock directly to select investors with regulatory approval. This method allows the company to raise funds quickly and efficiently without needing a public auction, similar to offering exclusive access to a limited number of buyers. For investors, it often provides an opportunity to purchase shares at a favorable price, while giving the company immediate access to capital.
accredited investors financial
"with certain accredited investors and/or qualified institutional buyers"
Accredited investors are individuals or entities considered to have enough financial knowledge and resources to understand and handle more complex and risky investments. They are often allowed to participate in private investment opportunities that are not available to the general public, similar to how experienced players might access exclusive clubs or events. This status helps ensure that investors can manage potential risks and rewards appropriately.
qualified institutional buyers financial
"with certain accredited investors and/or qualified institutional buyers"
Qualified institutional buyers are large organizations, like big investment firms or banks, that are allowed to buy certain types of investment opportunities not available to everyday investors. Their size and experience matter because it ensures they understand and can handle complex financial deals, making markets more efficient and secure.
shelf registration statement regulatory
"being offered pursuant to a shelf registration statement on Form S-3"
A shelf registration statement is a document a company files with regulators that allows it to sell shares or bonds quickly when it’s a good time to raise money. It’s like having a pre-approved plan ready so the company can act fast without going through lengthy paperwork each time they want to sell, making fundraising more flexible.
form s-3 regulatory
"a shelf registration statement on Form S-3 (File No. 333-282456)"
Form S-3 is a legal document companies use to register their stock sales with the government, making it easier and faster for them to raise money by selling shares to investors. It’s like having a pre-approved shopping list that lets a company quickly sell new shares when they need funds, without going through a lengthy approval process each time.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SAN DIEGO, Sept. 17, 2026 (GLOBE NEWSWIRE) -- Calidi Biotherapeutics, Inc. (NYSE American: CLDI) (“Calidi” or the “Company”), a biotechnology company pioneering the development of targeted genetic medicines, today announced that it has entered into a definitive stock purchase agreement with certain accredited investors and/or qualified institutional buyers for the purchase and sale of 1,025,640 shares of the Company’s common stock, in a registered direct offering, at a per share purchase price of $1.17.
  
The closing of the registered direct offering is expected to occur on or about September 18, 2026, subject to the satisfaction of customary closing conditions.

The gross proceeds to Calidi from the registered direct offering, before deducting offering expenses payable by the Company, are expected to be approximately $1.2 million. Calidi intends to use the net proceeds from the offering for working capital and for general corporate purposes.

The securities described above are being offered pursuant to a shelf registration statement on Form S-3 (File No. 333-282456), which was declared effective by the United States Securities and Exchange Commission (“SEC”) on October 10, 2024. The registered direct offering is being made only by means of a prospectus, including a prospectus supplement, which is part of the effective registration statement, that will be filed with the SEC. Electronic copies of the final prospectus supplement and accompanying prospectus may be obtained, when available, on the SEC’s website at http://www.sec.gov.
  
This press release shall not constitute an offer to sell or the solicitation of an offer to buy any of the securities described therein, nor shall there be any sales of these securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such jurisdiction.

About Calidi Biotherapeutics

Calidi Biotherapeutics (NYSE American: CLDI) is a biotechnology company pioneering the development of targeted therapies with the potential to deliver genetic medicines to distal sites of disease. The Company’s proprietary RedTail platform features an engineered enveloped oncolytic virus designed for systemic delivery and targeting of metastatic sites. This advanced enveloped technology is intended to shield the virus from immune clearance, allowing virotherapy to effectively reach tumor sites, induce tumor lysis, and deliver potent genetic medicine(s) to metastatic locations.

CLD-401, the lead candidate from the RedTail platform, currently in IND-enabling studies, targets metastatic non-small cell lung cancer, head and neck cancer, and other tumor types with high unmet medical need. Calidi continues to advance its pipeline utilizing the RedTail platform including its novel approach to incorporate in situ T-cell engagers in solid tumors.

Calidi Biotherapeutics is headquartered in San Diego, California. For more information, please visit www.calidibio.com or view Calidi’s Corporate Presentation here.

Forward-Looking Statements

This press release may contain forward-looking statements for purposes of the “safe harbor” provisions under the United States Private Securities Litigation Reform Act of 1995. Terms such as “anticipates,” “believe,” “continue,” “could,” “estimate,” “expect,” “intends,” “may,” “might,” “plan,” “possible,” “potential,” “predicts,” “project,” “should,” “towards,” “would” as well as similar terms, are forward-looking in nature, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include, but are not limited to, the Company’s plans strategies, priorities and key operational initiatives for fiscal year 2026 and 2027, statements concerning key milestones, including certain pre-clinical data, planned clinical trials, and statements relating to the safety and efficacy of Calidi’s therapeutic candidates in development. Any forward-looking statements contained in this discussion are based on Calidi’s current expectations and beliefs concerning future developments and their potential effects and are subject to multiple risks and uncertainties that could cause actual results to differ materially and adversely from those set forth or implied in such forward-looking statements. These risks and uncertainties include, but are not limited to, the risk that Calidi is not able to raise sufficient capital to support its current and anticipated clinical trials, the risk that early results of clinical trials do not necessarily predict final results and that one or more of the clinical outcomes may materially change following more comprehensive review of the data, and as more patient data becomes available, the risk that Calidi may not receive FDA approval for some or all of its therapeutic candidates; and, risks related to changes in applicable laws or regulations; manufacturing and supply chain matters; the availability of capital and other resources; and changes in business, market, economic or competitive conditions. Other risks and uncertainties are set forth in the section entitled “Risk Factors” and “Cautionary Note Regarding Forward-Looking Statements” in the Company’s annual report filed with the SEC on Form 10-K on March 27, 2026, as may be amended or supplemented by other reports we file with the SEC from time to time. We disclaim any obligation to update any forward-looking statement to reflect events or circumstances after the date of this press release or to reflect the occurrence of unanticipated events.

Investors Contact:
IR@calidibio.com 

Media Contact:
PR@calidibio.com 


FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What are the key terms of Calidi Biotherapeutics’ registered direct offering?

Calidi agreed to sell 1,025,640 shares of common stock at a purchase price of $1.17 per share in a registered direct offering, with expected gross proceeds of approximately $1.2 million before offering expenses.

When is the offering expected to close?

The closing of the registered direct offering is expected to occur on or about September 18, 2026, subject to the satisfaction of customary closing conditions.

How does Calidi intend to use the proceeds from this offering?

Calidi intends to use the net proceeds from the registered direct offering for working capital and general corporate purposes.

Under what registration statement is this offering being made?

The securities are being offered pursuant to a shelf registration statement on Form S-3 (File No. 333-282456), which was declared effective by the SEC on October 10, 2024.

Where can investors find the prospectus for this offering?

The registered direct offering is being made only by means of a prospectus, including a prospectus supplement that will be filed with the SEC. Electronic copies of the final prospectus supplement and accompanying prospectus may be obtained, when available, on the SEC’s website at http://www.sec.gov.

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