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MARKET LEADERS
52-WEEK LEADER
MGRT +3778%
Mega Fortune Company L..
2022 YTD LEADER
NINE +1131%
Nine Energy Service, I..
SEP 2022 LEADER
AKRO +169%
Akero Therapeutics, Inc.
📈 52-Week Top 5 Full List →
1 MGRT +3777.9% 2 SNDK +2426.2% 3 AXTI +1917.0% 4 ERAS +1071.6% 5 BW +898.6%
📅 2022 YTD Top 5 Full List →
1 NINE +1131.4% 2 META +689.1% 3 INDV +557.1% 4 TUSK +348.2% 5 RDUS +319.0%
🗓 September 2022 Top 5 Full List →
1 AKRO +169.2% 2 PRTA +120.2% 3 IMRX +106.0% 4 ELVN +105.4% 5 EVTL +79.3%
Quick Access: 52-Week 2022 YTD Sep 2022 Market Cap Dividends
#1 AKRO leads with +169% September 2022

Among the 3,411 NYSE, Nasdaq and NYSE American stocks currently eligible for this ranking, AKRO (Akero Therapeutics, Inc.) has the highest gain in September 2022 with +169%. Following are PRTA (+120%) and IMRX (+106%). Top performing sectors: Industrials (+38% avg, 1 in top 10), Healthcare (+35% avg, 9 in top 10), Consumer Cyclical (+27% avg).

Top Stock Gainers September 2022 - Monthly Performance Ranked

Track the top performing stocks of September 2022 ranked by monthly price gain. See which stock gainers delivered the highest gains this month, with market caps over $100 million on Nasdaq and NYSE.

Best performing large-cap stocks in September 2022

BIIB Biogen Inc. +33.64% $30.36B
CDE Coeur Mining, Inc. +30.53% $15.37B
KGC Kinross Gold Corporation +20.9% $28.07B
ASND Ascendis Pharma A/S +15.91% $16.69B
REGN Regeneron Pharmaceuticals, ... +14.69% $72.88B
2022
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

This ranking shows the top performing stocks and biggest stock gainers during September 2022, calculated from the first to the last trading day of the month. It shows which stocks are going up this month, with split-adjusted data used for consistent performance calculations.

Monthly performance rankings can reveal price strength, sustained momentum, sector rotation, and event-driven moves that are not visible in one-day movers lists. The table is informational only and does not recommend any stock to buy, sell, or hold.

September 2022 Stock Market Momentum

This page answers a current-month trend question with data: which NYSE and NASDAQ stocks have shown the strongest price gains so far in September 2022. The ranking is based on observed market performance, not analyst ratings, price targets, or investment recommendations.

Use the list to research momentum, market breadth, sector strength, and catalysts behind large moves. Before acting on any stock, review the company's news, SEC filings, liquidity, volatility, and your own risk constraints.

Looking for a specific Symbol?

September 2022 ranking, complete through September 30, 2022

29 stocks are withheld from this ranking because their price history is under review.

The gain covers the period above. Price, market cap, sector and country show each company as it is today, not as it was then.

Rank
Symbol
Company Name
Sep Gain
Market Cap (today)
Price (today)
Country
Sector
1
AKRO
Akero Therapeutics, Inc.
169.17%
3.59 B
$ 44.93
United States
Healthcare
2
PRTA
Prothena Corporation plc
120.23%
448.14 M
$ 8.56
Ireland
Healthcare
3
IMRX
Immuneering Corporation
106.04%
274.32 M
$ 4.24
United States
Healthcare
4
ELVN
Enliven Therapeutics, Inc.
105.41%
3.84 B
$ 53.76
United States
Healthcare
5
EVTL
Vertical Aerospace Ltd.
79.31%
171.89 M
$ 1.35
United Kingdom
Industrials
6
PLSE
Pulse Biosciences, Inc.
75.57%
2.45 B
$ 35.47
United States
Healthcare
7
SAVA
Cassava Sciences Inc
65.04%
114.97 M
$ 2.38
United States
Healthcare
8
ABOS
Acumen Pharmaceuticals, Inc.
64.7%
164.68 M
$ 2.28
United States
Healthcare
9
XFOR
X4 Pharmaceuticals, Inc.
64.42%
371.62 M
$ 3.94
United States
Healthcare
10
INNV
InnovAge Holding Corp.
62.43%
1.60 B
$ 11.81
United States
Healthcare
11
VTYX
Ventyx Biosciences Inc
58.75%
1.00 B
$ 14
United States
Healthcare
12
TERN
Terns Pharmaceuticals, Inc.
53.39%
6.12 B
$ 52.95
United States
Healthcare
13
IDYA
IDEAYA Biosciences, Inc.
52.24%
3.48 B
$ 36.16
United States
Healthcare
14
EVI
EVI Industries, Inc.
47.24%
194.32 M
$ 15.1
United States
Industrials
15
CRCT
Cricut, Inc.
46.75%
985.47 M
$ 4.695
United States
Technology
16
DWSN
Dawson Geophysical Company
44.55%
136.63 M
$ 4.4
United States
Energy
17
EVEX
Eve Holding, Inc.
44.15%
853.35 M
$ 2.45
United States
Industrials
18
NGD
New Gold Inc.
39.75%
7.21 B
$ 9.08
Canada
Basic Materials
19
AURA
Aura Biosciences, Inc.
36.34%
729.23 M
$ 7.05
United States
Healthcare
20
HROW
Harrow, Inc.
35.92%
1.47 B
$ 39.32
United States
Healthcare
21
TOP
TOP Financial Group Limited
35.16%
1.40 B
$ 2.26
Singapore
Financial Services
22
BIIB
Biogen Inc.
33.64%
30.36 B
$ 205.61
United States
Healthcare
23
INTA
Intapp, Inc.
32.41%
2.36 B
$ 30.6
United States
Technology
24
CDE
Coeur Mining, Inc.
30.53%
15.37 B
$ 14.91
United States
Basic Materials
25
MSC
Studio City International H...
30.36%
340.88 M
$ 1.77
Hong Kong
Consumer Cyclical
26
CVRX
CVRx, Inc.
29.4%
131.35 M
$ 4.95
United States
Healthcare
27
ETNB
89bio, Inc.
29.24%
1.28 B
$ 8.65
United States
Healthcare
28
QBTS
D-Wave Quantum Inc.
29.23%
6.53 B
$ 17.635
United States
Technology
29
HLVX
HilleVax, Inc.
28.98%
104.76 M
$ 2.09
United States
Healthcare
30
TYRA
Tyra Biosciences, Inc.
28.89%
1.85 B
$ 31.06
United States
Healthcare
31
NEOV
NeoVolta Inc.
28.32%
110.36 M
$ 2.01
United States
Industrials
32
SGML
Sigma Lithium Corporation
27.71%
1.06 B
$ 9.49
Canada
Basic Materials
33
AXGN
Axogen, Inc.
27.08%
2.19 B
$ 41.15
United States
Healthcare
34
PHAT
Phathom Pharmaceuticals, Inc.
26.77%
929.95 M
$ 11.66
United States
Healthcare
35
CTGO
Contango Silver & Gold Inc.
26.75%
528.59 M
$ 15.78
United States
Basic Materials
36
PRO
PROS Holdings, Inc.
26.15%
744.69 M
$ 15.48
United States
Technology
37
WIX
Wix.com Ltd.
25.73%
2.36 B
$ 56.34
Israel
Technology
38
COE
51Talk Online Education Group
25.49%
100.14 M
$ 16.67
Singapore
Consumer Defensive
39
CTKB
Cytek Biosciences, Inc.
25.17%
575.98 M
$ 4.46
United States
Healthcare
40
AAOI
Applied Optoelectronics, Inc.
24.77%
7.07 B
$ 88.14
United States
Technology
41
ASAN
Asana, Inc.
24.75%
1.89 B
$ 8.19
United States
Technology
42
LRMR
Larimar Therapeutics, Inc.
24.03%
397.87 M
$ 3.83
United States
Healthcare
43
MLCO
Melco Resorts & Entertainme...
23.46%
2.19 B
$ 5.64
Hong Kong
Consumer Cyclical
44
RLMD
Relmada Therapeutics, Inc.
23.44%
549.08 M
$ 5.23
United States
Healthcare
45
WVE
Wave Life Sciences Ltd.
22.79%
1.14 B
$ 5.92
Singapore
Healthcare
46
MRVI
Maravai LifeSciences Holdin...
21.98%
2.53 B
$ 6.86
United States
Healthcare
47
JANX
Janux Therapeutics, Inc.
21.87%
914.77 M
$ 15
United States
Healthcare
48
INSW
International Seaways, Inc.
21.6%
4.63 B
$ 93.6
United States
Energy
49
ERO
Ero Copper Corp.
21.55%
2.67 B
$ 25.6
Canada
Basic Materials
50
ARDX
Ardelyx, Inc.
21.43%
1.26 B
$ 5.085
United States
Healthcare
51
TRDA
Entrada Therapeutics, Inc.
21.23%
226.32 M
$ 5.83
United States
Healthcare
52
KGC
Kinross Gold Corporation
20.9%
28.07 B
$ 23.51
Canada
Basic Materials
53
CCLD
CareCloud, Inc.
20.81%
100.28 M
$ 2.36
United States
Healthcare
54
SMID
Smith-Midland Corporation
20.55%
155.38 M
$ 29.28
United States
Basic Materials
55
DYN
Dyne Therapeutics, Inc.
20.15%
4.28 B
$ 25.9
United States
Healthcare
56
IBRX
ImmunityBio, Inc.
20.05%
7.30 B
$ 6.97
United States
Healthcare
57
WK
Workiva Inc.
19.84%
3.13 B
$ 55.75
United States
Technology
58
QTRX
Quanterix Corporation
19.65%
164.40 M
$ 3.49
United States
Healthcare
59
AMLX
Amylyx Pharmaceuticals, Inc.
19.58%
2.17 B
$ 19.55
United States
Healthcare
60
ANTX
AN2 Therapeutics, Inc.
19.37%
169.28 M
$ 4.7
United States
Healthcare
61
MXCT
MaxCyte, Inc.
19.27%
112.48 M
$ 1.05
United States
Healthcare
62
HLIT
Harmonic Inc.
19.14%
1.20 B
$ 11.06
United States
Technology
63
TNK
Teekay Tankers Ltd.
18.81%
2.66 B
$ 76.78
Bermuda
Energy
64
RZLT
Rezolute, Inc.
18.61%
473.76 M
$ 4.92
United States
Healthcare
65
BEBE
TGE Value Creative Solution...
18.43%
199.80 M
$ 9.99
France
Financial Services
66
WFRD
Weatherford International plc
18.15%
6.16 B
$ 85.92
United States
Energy
67
OPOF
Old Point Financial Corpora...
18.1%
214.80 M
$ 42.1
United States
Financial Services
68
NRC
NRC Health
17.93%
503.47 M
$ 22.34
United States
Healthcare
69
MOLN
Molecular Partners AG
17.16%
143.68 M
$ 3.8303
Switzerland
Healthcare
70
FRPT
Freshpet, Inc.
16.79%
3.01 B
$ 61.22
United States
Consumer Defensive
71
NCNO
nCino, Inc.
16.18%
2.03 B
$ 18.51
United States
Technology
72
ASND
Ascendis Pharma A/S
15.91%
16.69 B
$ 254.44
Denmark
Healthcare
73
FOA
Finance of America Companie...
15.63%
217.61 M
$ 24.35
United States
Financial Services
74
THTX
Theratechnologies Inc.
15.61%
150.81 M
$ 3.28
Canada
Healthcare
75
CINT
CI&T Inc.
15.5%
421.59 M
$ 3.28
Brazil
Technology
76
IFRX
InflaRx N.V.
15.28%
248.92 M
$ 1.69
Germany
Healthcare
77
CCRN
Cross Country Healthcare, Inc.
15.14%
428.06 M
$ 13.25
United States
Healthcare
78
FSM
Fortuna Mining Corp.
15.07%
2.55 B
$ 8.42
Canada
Basic Materials
79
ATEC
Alphatec Holdings, Inc.
15%
1.43 B
$ 9.32
United States
Healthcare
80
REGN
Regeneron Pharmaceuticals, ...
14.69%
72.88 B
$ 695.18
United States
Healthcare
81
NG
NovaGold Resources Inc.
14.67%
2.55 B
$ 5.82
Canada
Basic Materials
82
NUVL
Nuvalent Inc
14.49%
9.81 B
$ 123.96
United States
Healthcare
83
ANIX
Anixa Biosciences, Inc.
14.42%
119.76 M
$ 3.52
United States
Healthcare
84
XMTR
Xometry, Inc.
14.2%
4.75 B
$ 85.92
United States
Industrials
85
PEN
Penumbra, Inc.
14.04%
12.59 B
$ 319.99
United States
Healthcare
86
EGO
Eldorado Gold Corporation
13.99%
8.40 B
$ 32.24
Canada
Basic Materials
87
DNA
Ginkgo Bioworks Holdings, Inc.
13.87%
503.00 M
$ 7.7
United States
Healthcare
88
ZVRA
Zevra Therapeutics, Inc.
13.66%
574.01 M
$ 9.71
United States
Healthcare
89
ISSC
Innovative Aerosystems, Inc.
13.55%
342.83 M
$ 19.16
United States
Industrials
90
CWAN
Clearwater Analytics Holdin...
13.45%
7.33 B
$ 24.56
United States
Technology
91
PRTH
Priority Technology Holding...
13.32%
567.43 M
$ 6.89
United States
Technology
92
SSRM
SSR Mining Inc.
12.98%
5.27 B
$ 25.41
United States
Basic Materials
93
ZS
Zscaler, Inc.
12.91%
23.82 B
$ 147.3
United States
Technology
94
CFFI
C&F Financial Corporation
12.63%
271.37 M
$ 83.49
United States
Financial Services
95
IBEX
IBEX Limited
12.48%
480.27 M
$ 35.87
United States
Technology
96
SCPH
scPharmaceuticals Inc.
12.41%
302.21 M
$ 5.63
United States
Healthcare
97
FSBC
Five Star Bancorp
12.32%
1.02 B
$ 47.83
United States
Financial Services
98
WALD
Waldencast plc
11.98%
220.61 M
$ 1.72
United Kingdom
Consumer Defensive
99
LQDA
Liquidia Corporation
11.93%
7.72 B
$ 86.82
United States
Healthcare
100
TMCI
Treace Medical Concepts, Inc.
11.92%
260.14 M
$ 4.01
United States
Healthcare
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q Which stock has gained the most in September 2022?
A

AKRO (Akero Therapeutics, Inc.) has the highest monthly gain in this ranking for September 2022, with a gain of 169%. Top performers this month include AKRO, PRTA, IMRX.

Q What stocks gained the most in September 2022?
A

The biggest gainers in September 2022 were: AKRO (+169%), PRTA (+120%), IMRX (+106%), ELVN (+105%), EVTL (+79%). These monthly rankings show which stocks had the strongest short-term momentum.

Q Does this page recommend the best stocks to buy now?
A

No. This page is an informational ranking of stocks that have already gone up during September 2022. It does not make buy, sell, or hold recommendations and should be used as a research starting point, not financial advice.

Q How can this ranking help explain current stock market trends?
A

The ranking shows where price strength is concentrated during September 2022. Comparing the top gainers by sector, market cap, and recent catalysts can help identify momentum themes and market rotation without implying that any listed stock is a recommendation.

Q Which sectors performed best in September 2022?
A

The top performing sectors in September 2022 included Healthcare, Industrials, based on the stocks with highest monthly gains. AKRO led the Healthcare sector.

Q How is monthly stock performance calculated?
A

Monthly stock performance is calculated by comparing the closing price on the last trading day of the month to the opening price on the first trading day. Split-adjusted prices ensure accuracy.

Q Where can I find today's top stock gainers and most active stocks?
A

This page ranks stocks by their full-month performance in September 2022. For today's top stock gainers, real-time stock movers, and the most active stocks right now, visit our Momentum Scanner which tracks live intraday market activity across NYSE and NASDAQ.

Understanding Monthly Stock Performance

Monthly performance rankings reveal short-term momentum patterns and help identify stocks experiencing rapid price movements:

  • Momentum Research: Stocks showing strong monthly performance can help identify where market attention and price strength are concentrated.
  • Sector Rotation: Monthly rankings can reveal which sectors are gaining favor with investors and where market leadership is shifting.
  • Event-Driven Moves: Earnings releases, product launches, and regulatory approvals often create significant monthly price movements.

Using Monthly Data Effectively

  • Combine Timeframes: Compare monthly gainers with 52-week and YTD performance to identify stocks with both short and long-term momentum.
  • Research the Catalyst: Investigate why top monthly performers moved significantly. The reason for the move matters as much as the percentage gain.
  • Watch for Reversals: Extreme monthly gains sometimes precede corrections, so treat the ranking as a research starting point rather than a buy list.

Evaluate Your Positions

Researching one of this month's top movers? Use our Stock Return Calculator to review historical performance, or the Position Size Calculator to model position sizing and risk before making your own decision.