[Form 4] Guardant Health, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Insider stock changes at Guardant Health (GH): On 09/15/2025 Chief Information Officer Kumud Kalia had 638 restricted stock units vest, resulting in 638 shares issued to her and retained 324 shares that were sold to satisfy tax withholding at a price of $54.79 per share. After these transactions Kalia beneficially owns 19,488 shares of Common Stock. The Form 4 was signed by an attorney-in-fact on 09/17/2025.

Positive

• Vesting occurred as scheduled for the RSU grant, indicating equity compensation is being administered per plan
• Clear disclosure of shares withheld for tax and the withholding price ($54.79) provides transparent reporting

Negative

• Shares were surrendered (324) to cover tax withholding which reduced net issued shares to the reporting person

Insights

Securities Analyst

TL;DR: Routine RSU vesting and tax-withholding sale by an officer; change in beneficial ownership is small relative to typical public-company floats.

The filing documents a scheduled vesting of 638 restricted stock units and a corresponding company-withheld disposition of 324 shares to satisfy tax obligations at $54.79 per share. Post-transaction beneficial ownership is 19,488 shares. This is a standard administrative transaction tied to equity compensation rather than an open-market trade or a strategic stake change.

Corporate Governance Expert

TL;DR: Disclosure is complete for the transactions reported; signature was provided by an attorney-in-fact.

The Form 4 lists the reporting person as the Chief Information Officer and shows individual filing status. The explanations clarify the tax-withholding mechanics and vesting schedule for the RSU award originally granted 06/09/2023. The filing includes a dated signature block signed by an attorney-in-fact, meeting procedural requirements for Section 16 reporting.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Kalia Kumud

(Last) (First) (Middle)

3100 HANOVER STREET

(Street)

PALO ALTO CA 94304

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Guardant Health, Inc. [ GH ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Information Officer

3. Date of Earliest Transaction (Month/Day/Year)
09/15/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	09/15/2025		M		638	A	$0	19,488	D
Common Stock	09/15/2025		F		324(1)	D	$54.79	19,164	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Restricted Stock Units	$0	09/15/2025		M			638	(2)	(3)	Common Stock	638	$0	1,912	D

Explanation of Responses:

1. These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

2. This represents a restricted stock unit award granted on June 9, 2023 that vests over a three-year period. 33% of the shares subject to such award vested on June 15, 2024. The remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

3. Not applicable for Restricted Stock Units.

Remarks:

	/s/ John G. Saia, as attorney-in-fact for Kumud Kalia	09/17/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What transactions did Kumud Kalia report on the Form 4 for GH?

The Form 4 reports 638 RSUs vested on 09/15/2025 and a company-withheld disposition of 324 shares at $54.79 per share to cover taxes.

How many shares does Kumud Kalia beneficially own after the reported transactions?

Following the transactions the filing reports 19,488 shares of Guardant Health Common Stock beneficially owned.

When was the RSU grant originally awarded and what is the vesting schedule?

The RSU award was granted on 06/09/2023 and vests over three years: 33% vested on 06/15/2024 and the remaining 67% vests in equal quarterly installments over the next two years.

Why were 324 shares disposed of according to the Form 4?

The company retained 324 shares to satisfy the reporting-holder's tax withholding obligations related to the RSU vesting; the retained amount was not in excess of the tax liability.

Who signed the Form 4 and when?

The Form 4 was signed by John G. Saia, as attorney-in-fact for Kumud Kalia on 09/17/2025.