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111, Inc. (NASDAQ: YI) trims 2025 revenue while edging toward operating profit

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Form Type
6-K

Rhea-AI Filing Summary

111, Inc. reported fourth quarter and full-year 2025 results showing lower revenue but improved profitability metrics as it shifts to an asset-light warehouse partnership model.

Net revenues were RMB12.6 billion for 2025, down 12.8% from 2024, while operating costs fell by the same percentage. GAAP loss from operations was RMB2.4 million, compared with RMB2.1 million of operating income in 2024, but non-GAAP income from operations remained positive at RMB7.7 million.

For Q4 2025, net revenues declined 26.7% year over year to RMB2.8 billion, yet loss from operations narrowed sharply to RMB0.3 million and non-GAAP income from operations reached RMB0.2 million. The company generated positive operating cash flow of RMB119.1 million for 2025 and ended the year with RMB611.3 million in cash, restricted cash and short-term investments.

Positive

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Insights

Revenue fell, but margins, cash flow and balance sheet quality improved modestly.

111, Inc. is deliberately shrinking its asset base by divesting subsidiaries and using a warehouse partnership model. This reduced 2025 net revenues to RMB12.6 billion, down 12.8%, but operating costs declined at the same pace, preserving gross and operating margin levels.

Profitability metrics improved on a run-rate basis. Q4 2025 loss from operations narrowed to just RMB0.3 million, and non-GAAP income from operations turned positive at RMB0.2 million. For the full year, non-GAAP operating income was RMB7.7 million, indicating the core business is approaching breakeven despite lower scale.

Liquidity appears more robust with cash, restricted cash and short-term investments rising to RMB611.3 million as of December 31, 2025, up from RMB518.3 million a year earlier. However, the company still carries RMB1.12 billion owed to investors in 1 Pharmacy Technology, with phased repayment arrangements and a RMB189.0 million repayment completed in February 2026, so leverage and funding commitments remain a key watchpoint.

2025 Net revenues RMB12.6 billion Full year 2025, down 12.8% from RMB14.4 billion in 2024
Q4 2025 Net revenues RMB2.8 billion Quarter ended December 31, 2025, down 26.7% year over year
2025 non-GAAP income from operations RMB7.7 million Full year 2025, vs RMB22.3 million in 2024
Q4 2025 non-GAAP income from operations RMB0.2 million Quarter ended December 31, 2025, vs RMB2.3 million non-GAAP loss in Q4 2024
2025 net loss RMB22.5 million Full year 2025, compared with RMB20.8 million in 2024
Cash, restricted cash and short-term investments RMB611.3 million As of December 31, 2025; up from RMB518.3 million at December 31, 2024
2025 operating cash flow RMB119.1 million Net cash provided by operating activities for full year 2025
Obligation to 1 Pharmacy Technology investors RMB1.12 billion Included in redeemable non-controlling interests and accrued liabilities
warehouse partnership model financial
"our transition to a warehouse partnership model—where we generate recurring commission income"
non-GAAP income from operations financial
"Non-GAAP income from operations was RMB7.7 million"
Non-GAAP income from operations is a measure of a company's profit from its core business activities, calculated without including certain expenses or income that are typically added back or excluded in standard accounting reports. It provides a clearer picture of how well the company's main operations are performing by removing items like one-time costs or gains that might distort the overall results. Investors use it to better understand the company's ongoing profitability, separate from unusual or non-recurring items.
redeemable non-controlling interests financial
"amount of RMB1.12 billion has been included in the balances of redeemable non-controlling interests"
Redeemable non-controlling interests are ownership stakes in a company’s unit held by outside investors that can be forced to be bought back by the parent company for cash or a set value. Think of it like a part-owner who has the contractual right to ‘cash out’ their share; for investors this matters because it can create a future cash obligation, change reported equity versus debt, and affect earnings and ownership percentages.
ADS financial
"Every one ADS represents twenty Class A ordinary shares"
Ads are paid promotional messages a company places across media — online, on TV, in print, or on social platforms — to attract customers, explain products, or shape public perception. For investors, ads matter because they drive sales growth, affect how much a company must spend to win customers, and influence brand strength and long-term value. Ads can also create regulatory or reputational risk if claims are misleading, which can affect profits and stock price.
asset-light financial
"reinforces our focus on pursuing asset-light, profitable growth"
A business described as "asset-light" relies on few owned physical assets—such as factories, real estate, or heavy equipment—and instead uses partners, contractors, or lease arrangements to deliver products or services. For investors, this model can mean lower upfront investment, faster scaling and often higher profit margins, but it also increases dependence on outside providers and can create less predictable costs and supply risks—like renting tools instead of owning them.

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 6-K

 

REPORT OF FOREIGN ISSUER
PURSUANT TO RULE 13a-16 OR 15d-16 OF
THE SECURITIES EXCHANGE ACT OF 1934

 

For the month of April 2026

 

Commission file number: 001-38639

 

111, Inc.

10th Floor, T1, Yuzhongxin, No. 268 Yubei Road

Pudong New Area

Shanghai, 201204

The People’s Republic of China

(Address of principal executive offices)

 

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.    Form 20-F    Form 40-F

 

 

 

EXHIBIT INDEX

 

Exhibit No.   Description
     
99.1   111, Inc. Announces Fourth Quarter and Fiscal Year 2025 Financial Results

 

 

 

 

Signature

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

    111, INC.
     
Date: April 9, 2026   By: /s/ Junling Liu
        Name: Junling Liu
        Title: Chief Executive Officer

 

 

 

 

Exhibit 99.1

 

 

111, Inc. Announces Fourth Quarter and Fiscal Year 2025 Financial Results

 

·Continuing Transition to an Asset-Light Business Model to Improve Overall Efficiency

 

·Delivered Non-GAAP Operating Profitability in Both Q4'25 and FY'25

 

·Generated Positive Operating Cash Flow for Both Q4'25 and FY'25

 

·Continued Gross Profit Margin Expansion for B2B Business in Both Q4’25 and FY'25

 

SHANGHAI, April 9, 2026 /PRNewswire/ – 111, Inc. (“111” or the “Company”) (NASDAQ: YI), a leading tech-enabled healthcare platform company committed to reshaping the value chain of healthcare industry by digitally empowering the upstream and downstream in China, today announced its unaudited financial results for the fourth quarter and fiscal year ended December 31, 2025.

 

2025 Executing Strategic Optimization: Embraces Asset-Light Partnership Network Growth

 

In 2025, the Company proactively implemented strategic structural optimization by divesting its 100% equity interests in several subsidiaries. While this structural optimization created a temporary headwind for top-line revenue, these facilities have now joined our ecosystem as fulfillment partners and are dedicated to serving our customers exclusively. Through the divestiture of these entities and our transition to a warehouse partnership modelwhere we generate recurring commission income rather than bearing the operational and capital burdenswe have successfully driven continued margin expansion. By optimizing our network and selectively exiting underperforming fulfillment centers, we have strengthened our ability to further improve our profitability and liquidity profile in the future.

 

Fourth Quarter 2025 Highlights

 

·Net revenues were RMB2.8 billion (US$403.3 million) and gross segment profit (1) was RMB164.9 million (US$23.6 million). Due to the strategic optimization, gross margin continued to expand. B2B gross profit margin reached 5.6%, representing an improvement of 60 basis points from 5.0% in the same quarter of 2024.

 

·Total operating expenses were RMB165.2 million (US$23.6 million), representing a decrease of 21.3% compared to RMB209.8 million in the same quarter of 2024, highlighting continued cost optimization and efficiency gains.

 

·Non-GAAP income from operations (2) was RMB0.2 million (US$0.03 million), compared to a non-GAAP loss from operations of RMB2.3 million in the same quarter of 2024. The Company achieved non-GAAP operating profitability in the quarter, marking a year-over-year turnaround from loss to profit.

 

·Net cash provided by operating activities was RMB29.9 million (US$4.3 million). The Company achieved a meaningful operating cash flow turnaround, moving from negative to positive year-over-year, underscoring stronger business fundamentals and improved financial health.

 

Fiscal Year 2025 Highlights

 

·Net revenues were RMB12.6 billion (US$1.8 billion) and gross segment profit was RMB723.4 million (US$103.4 million). Due to the strategic optimization, B2B gross profit margin rose 10 basis points from 5.4% to 5.5% year-over-year, reflecting continued optimization of core operations.

 

·Total operating expenses were RMB725.8 million (US$103.8 million), representing a decrease of 12.3% compared to RMB827.1 million in the prior year. The Company continued to focus on operational efficiency and disciplined cost management.

 

·Non-GAAP income from operations was RMB7.7 million (US$1.1 million), compared to RMB22.3 million in 2024. The year-over-year decrease reflected the intentional reduction in revenue scale resulting from the strategic transition, partially offset by continued gross margin expansion. Importantly, the Company maintained non-GAAP operating profitability for both 2025 and 2024, marking a key milestone on the path toward sustainable earnings.

 

·Net cash provided by operating activities was RMB119.1 million (US$17.0 million). The Company delivered annual positive operating cash flow for both 2025 and 2024, demonstrating improved financial discipline and business quality.

 

·Cash and cash equivalents, restricted cash and short-term investments amounted to RMB611.3 million (US$87.4 million) as of December 31, 2025, representing an increase of 17.9% compared to the end of 2024.

 

(1) Gross segment profit represents net revenues less cost of goods sold. 

(2) Non-GAAP income (loss) from operations represents income (loss) from operations excluding share-based compensation expenses.

 

1

 

 

Mr. Junling Liu, Co-Founder, Chairman, and Chief Executive Officer of 111, commented, "2025 marked a pivotal year for 111, as we steadily advanced our transition to a warehouse partnership model and achieved a key profitability milestone. We delivered non-GAAP operating profitability and positive operating cash flow for both the quarter and the full year. These results underscore the strength of our platform and validate the strategic direction we have set for the Company."

 

"In 2025, we proactively implemented strategic structural optimization by divesting 100% equity interests in several subsidiaries. Through the divestiture of these entities and our transition to a warehouse partnership model—where we generate recurring commission income rather than bearing operational and capital burdens—we achieved sustained gross margin expansion for the B2B business. We believe this initiative reinforces our focus on pursuing asset-light, profitable growth, strengthening our ability to scale the warehouse partnership network efficiently while maintaining a healthier financial structure."

 

"Our strategic initiatives are yielding significant results. Promotional products are rapidly reaching pharmacies nationwide through the 111 digital marketing platform. Revenue from all marketing-promoted products increased by 76.2% and gross profit rose 81.7% compared to the same quarter last year. As a notable promotional product, "Cravit" has become our flagship star product, whose monthly sales volume rose sharply from 20,000 boxes at launch in March to a monthly peak of 290,000 boxes in November 2025. GMV generated by the product in 2025 also increased by 368.2% on a year-over-year basis. This success underscores our unique marketing capabilities and has delivered strong momentum to both our upstream and downstream partners."

 

"Looking ahead, with our solid foundation and strategic optimization, we are well positioned for sustainable, high-quality growth. We have deeply integrated AI applications across our operations to drive meaningfully enhanced efficiency, and will continue to focus on leading the Company's evolution from a digital to an intelligent ecosystem—creating durable long-term opportunities for our partners, customers, and shareholders. Through a more streamlined and intelligent operating model, we aim to drive consistent margin expansion, improve profitability, and deliver enduring value to all stakeholders."

 

Fourth Quarter 2025 Financial Results

 

Net revenues were RMB2.8 billion (US$403.3 million), representing a decrease of 26.7% from RMB3.8 billion in the same quarter of 2024.

 

(In thousands RMB) 

 

For the three months ended December 31, 

  

2024

 

2025 

 

YoY 

B2B Net Revenue         
Product   3,759,824    2,742,449    -27.1%
Service   21,771    21,721    -0.2%
                
Sub-Total   3,781,595    2,764,170    -26.9%
                
Cost of Products Sold (3)   3,592,588    2,609,356    -27.4%
                
Segment Profit   189,007    154,814    -18.1%
Segment Profit %   5.0%   5.6%     

 

2

 

 

(In thousands RMB) 

  For the three months ended December 31,
  

2024 

 

2025 

 

YoY 

B2C Net Revenue         
Product   62,480    53,027    -15.1%
Service   3,700    2,967    -19.8%
                
Sub-Total   66,180    55,994    -15.4%
                
Cost of Products Sold   52,705    45,912    -12.9%
                
Segment Profit   13,475    10,082    -25.2%
Segment Profit %   20.4%   18.0%     

 

(3) For segment reporting purposes, purchase rebates are allocated to the B2B segment and B2C segments primarily based on the amount of cost of products sold for each segment. Cost of products sold does not include other direct costs related to cost of product sales such as shipping and handling expense, payroll and benefits of logistic staff, logistic centers rental expenses and depreciation expenses, which are recorded in the fulfillment expenses.

 

Operating costs and expenses were RMB2.8 billion (US$403.3 million), representing a decrease of 26.8% from RMB3.9 billion in the same quarter of 2024.

 

·Cost of products sold was RMB2.7 billion (US$379.7 million), representing a decrease of 27.2% from RMB3.6 billion in the same quarter of 2024.

 

·Fulfillment expenses were RMB74.1 million (US$10.6 million), representing a decrease of 29.1% from RMB104.5 million in the same quarter of 2024. Fulfillment expenses accounted for 2.6% of net revenues this quarter as compared to 2.7% in the same quarter of 2024.

 

·Selling and marketing expenses were RMB62.7 million (US$9.0 million), representing a decrease of 17.6% from RMB76.2 million in the same quarter of 2024. Excluding the share-based compensation expenses of RMB0.6 million for the quarter and RMB1.8 million for the same quarter of 2024, respectively, selling and marketing expenses as a percentage of net revenues accounted for 2.2% in the quarter as compared to 1.9% in the same quarter of 2024.

 

·General and administrative expenses were RMB18.0 million (US$2.6 million), representing a decrease of 10.6% from RMB20.2 million in the same quarter of 2024. Excluding the share-based compensation expenses, general and administrative expenses as a percentage of net revenues accounted for 0.6% in the quarter as compared to 0.5% in the same quarter of 2024.

 

·Technology expenses were RMB14.8 million (US$2.1 million), representing a decrease of 4.2% from RMB15.4 million in the same quarter of 2024. Excluding the share-based compensation expenses of RMB0.1 million for the quarter and RMB1.0 million for the same quarter 2024, respectively, technology expenses as a percentage of net revenues accounted for 0.5% in the quarter as compared to 0.4% in the same quarter of 2024.

 

3

 

 

Loss from operations was RMB0.3 million (US$0.05 million), representing a significant 95.6% narrowing compared to a loss of RMB7.3 million in the same quarter of 2024. As a percentage of net revenues, loss from operations accounted for 0.01% in the quarter, down from 0.2% in the same quarter of 2024.

 

Non-GAAP income from operations was RMB0.2 million (US$0.03 million), compared to a non-GAAP loss from operations of RMB2.3 million in the same quarter of 2024, marking a year-over-year turnaround from loss to profit.

 

Net loss was RMB6.5 million (US$0.9 million), representing an improvement of 48.3% from RMB12.5 million in the same quarter of 2024. As a percentage of net revenues, net loss accounted for 0.2% in the quarter, down from 0.3% in the same quarter of 2024.

 

Non-GAAP net loss (4) was RMB5.9 million (US$0.9 million), representing an improvement of 20.9% from RMB7.5 million in the same quarter of 2024. As a percentage of net revenues, non-GAAP net loss accounted for 0.2% in the quarter, consistent with the same period last year.

 

Net loss attributable to ordinary shareholders was RMB16.2 million (US$2.3 million), representing an improvement of 18.2% from RMB19.8 million in the same quarter of 2024. As a percentage of net revenues, net loss attributable to ordinary shareholders accounted for 0.6% in the quarter as compared to 0.5% in the same quarter of 2024.

 

Non-GAAP net loss attributable to ordinary shareholders (5) was RMB15.7 million (US$2.2 million), compared to RMB14.8 million in the same quarter of last year. As a percentage of net revenues, non-GAAP net loss attributable to ordinary shareholders accounted for 0.6% in the quarter as compared to 0.4% in the same quarter of 2024.

 

(4) Non-GAAP net loss represents net loss excluding share-based compensation expenses, net of tax. Considering the impact of accretion of redeemable non-controlling interest for the fourth quarter and fiscal year ended December 31, 2025, non-GAAP net loss is used as a meaningful measurement of the operation performance of the Company.

 

(5) Non-GAAP net loss attributable to ordinary shareholders represents net loss attributable to ordinary shareholders excluding share-based compensation expenses, net of tax.

 

Fiscal Year 2025 Financial Results

 

Net revenues were RMB12.6 billion (US$1.8 billion), representing a decrease of 12.8% from RMB14.4 billion in the previous year.

 

(In thousands RMB) 

  For the year ended December 31,
   2024  2025  YoY
B2B Net Revenue         
Product   14,033,543    12,247,430    -12.7%
Service   89,609    73,775    -17.7%
                
Sub-Total   14,123,152    12,321,205    -12.8%
                
Cost of Products Sold   13,357,617    11,641,681    -12.8%
                
Segment Profit   765,535    679,524    -11.2%
Segment Profit %   5.4%   5.5%     

 

4

 

 

(In thousands RMB) 

  For the year ended December 31,
   2024  2025  YoY
B2C Net Revenue         
Product   261,197    223,217    -14.5%
Service   16,900    11,601    -31.4%
                
Sub-Total   278,097    234,818    -15.6%
                
Cost of Products Sold   214,403    190,936    -10.9%
                
Segment Profit   63,694    43,882    -31.1%
Segment Profit %   22.9%   18.7%     

  

Operating costs and expenses were RMB12.6 billion (US$1.8 billion), representing a decrease of 12.8% from RMB14.4 billion in 2024.

 

·Cost of products sold was RMB11.8 billion (US$1.7 billion), representing a decrease of 12.8% from RMB13.6 billion in 2024.

 

·Fulfillment expenses were RMB345.2 million (US$49.4 million), representing a decrease of 9.4% from RMB381.0 million in 2024. Fulfillment expenses accounted for 2.7% of net revenues in 2025 as compared to 2.6% in 2024.

 

·Selling and marketing expenses were RMB258.6 million (US$37.0 million), representing a decrease of 17.6% from RMB313.9 million in the previous year. Excluding the share-based compensation expenses of RMB4.0 million for 2025 and RMB6.9 million for 2024, respectively, selling and marketing expenses as a percentage of net revenues, decreased to 2.0% in 2025 from 2.1% in 2024.

 

·General and administrative expenses were RMB69.5 million (US$9.9 million), representing a decrease of 2.0% from RMB70.9 million in 2024. Excluding the share-based compensation expenses of RMB4.9 million for 2025 and RMB9.2 million for 2024, respectively, general and administrative expenses accounted for 0.5% of net revenues in 2025 as compared to 0.4% in 2024.

 

·Technology expenses were RMB60.4 million (US$8.6 million), representing a decrease of 13.3% from RMB69.6 million in 2024. Excluding the share-based compensation expenses of RMB1.1 million for 2025 and RMB4.0 million for 2024, respectively, technology expenses accounted for 0.5% of net revenues in 2025, maintaining the same percentage as 2024.

 

Loss from operations was RMB2.4 million (US$0.3 million), compared to income from operations of RMB2.1 million in 2024.

 

Non-GAAP income from operations was RMB7.7 million (US$1.1 million), compared to RMB22.3 million in 2024. As a percentage of net revenues, non-GAAP income from operations accounted for 0.1% in 2025 as compared to 0.2% in 2024.

 

Net loss was RMB22.5 million (US$3.2 million), compared to RMB20.8 million in 2024. As a percentage of net revenues, net loss accounted for 0.2% in 2025 as compared to 0.1% in 2024.

 

Non-GAAP net loss was RMB12.5 million (US$1.8 million), compared to RMB0.6 million in 2024. As a percentage of net revenues, non-GAAP net loss accounted for 0.1% in 2025 as compared to 0.004% in 2024.

 

Net loss attributable to ordinary shareholders was RMB66.4 million (US$9.5 million), compared to RMB64.7 million in 2024. As a percentage of net revenues, net loss attributable to ordinary shareholders accounted for 0.5% in 2025 as compared to 0.4% in 2024.

 

Non-GAAP net loss attributable to ordinary shareholders was RMB56.3 million (US$8.1 million), compared to RMB44.6 million in 2024.  As a percentage of net revenues, non-GAAP net loss attributable to ordinary shareholders accounted for 0.4% in 2025, up from 0.3% in 2024.

 

5

 

 

As of December 31, 2025, the Company held cash and cash equivalents, restricted cash and short-term investments totaling RMB611.3 million (US$87.4 million), compared to RMB518.3 million as of December 31, 2024. To date, amount of RMB1.12 billion has been included in the balances of redeemable non-controlling interests and accrued expenses and other current liabilities. This amount is owed to a group of investors of 1 Pharmacy Technology pursuant to equity investments made in 2020, as previously disclosed. 111 has received redemption requests from certain of such investors in accordance with the terms of their initial investments in 1 Pharmacy Technology. Following communication and negotiation, the Company has further reached agreements with, or received commitment letters from, all investors to reschedule the repayments, allowing for phased repayments at extended periods, if the investors exercise their redemption rights. In February 2026, the Company made repayments of approximately RMB189.0 million (US$27.0 million) to all investors of 1 Pharmacy Technology. For further details about such investors’ investments in 1 Pharmacy Technology, please see “Item 4. Information on the Company-A. History and Development of the Company” in the Company’s annual report for the fiscal year ended December 31, 2024.

 

Use of Non-GAAP Financial Measures

 

In evaluating the business, the Company considers and uses non-GAAP income (loss) from operations, non-GAAP net loss, non-GAAP net loss attributable to ordinary shareholders, and non-GAAP loss per ADS, as supplemental measures to review and assess its operating performance. The Company defines non-GAAP income (loss) from operations as income (loss) from operations excluding share-based compensation expenses. The Company defines non-GAAP net loss as net loss excluding share-based compensation expenses, net of tax. The Company defines non-GAAP net loss attributable to ordinary shareholders as net loss attributable to ordinary shareholders excluding share-based compensation expenses, net of tax. The Company defines non-GAAP loss per ADS as net loss attributable to ordinary shareholders per ADS excluding share-based compensation expenses, net of tax per ADS. The presentation of these non-GAAP financial measures is not intended to be considered in isolation or as a substitute for the financial information prepared and presented in accordance with U.S. GAAP.

 

The Company believes that non-GAAP income (loss) from operations, non-GAAP net loss, non-GAAP net loss attributable to ordinary shareholders, and non-GAAP loss per ADS help identify underlying trends in its business that could otherwise be distorted by the effect of certain expenses that it includes in income (loss) from operations and net loss. Share-based compensation expenses is a non-cash expense that varies from period to period. As a result, management excludes the items from its internal operating forecasts and models. Management believes that the adjustments for share-based compensation expenses provide investors with a reasonable basis to measure the company's core operating performance, in a more meaningful comparison with the performance of other companies. The Company believes that non-GAAP income (loss) from operations, non-GAAP net loss, non-GAAP net loss attributable to ordinary shareholders, and non-GAAP loss per ADS provide useful information about its operating results, enhances the overall understanding of its past performance and future prospects and allow for greater visibility with respect to key metrics used by the management in their financial and operational decision-making.

 

The non-GAAP financial measures are not defined under U.S. GAAP and are not presented in accordance with U.S. GAAP. The non-GAAP financial measures have limitations as analytical tools. One of the key limitations of using non-GAAP income (loss) from operations, non-GAAP net loss, non-GAAP net loss attributable to ordinary shareholders, or non-GAAP loss per ADS is that it does not reflect all items of income and expense that affect the Company's operations. Further, the non-GAAP financial measures may differ from the non-GAAP information used by other companies, including peer companies, and therefore their comparability may be limited.

 

The Company compensates for these limitations by reconciling the non-GAAP financial measures to the most comparable U.S. GAAP measures, all of which should be considered when evaluating the Company's performance. The Company encourages you to review its financial information in its entirety and not rely on a single financial measure.

 

Reconciliation of the non-GAAP financial measures to the most comparable U.S. GAAP measures is included at the end of this press release.

 

Exchange Rate Information Statement

 

This announcement contains translations of certain RMB amounts into U.S. dollars at specified rates solely for the convenience of the reader. Unless otherwise noted, all translations from RMB to U.S. dollars are made at a rate of RMB6.9931 to US$1.00, the exchange rate set forth in the H.10 statistical release of the Board of Governors of the Federal Reserve System as of December 31, 2025.

 

6

 

 

Forward-Looking Statements

 

This press release contains forward-looking statements. These statements constitute "forward-looking" statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," "target," "confident" and similar statements. Among other things, the Business Outlook and quotations from management in this announcement, as well as 111's strategic and operational plans, contain forward-looking statements. 111 may also make written or oral forward-looking statements in its periodic reports to the U.S. Securities and Exchange Commission, in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Such statements are based upon management's current expectations and current market and operating conditions and relate to events that involve known or unknown risks, uncertainties and other factors, all of which are difficult to predict and many of which are beyond the Company's control. Forward-looking statements involve inherent risks, uncertainties and other factors that could cause actual results to differ materially from those contained in any such statements. Potential risks and uncertainties include, but are not limited to, uncertainties as to the Company's ability comply with extensive and evolving regulatory requirements, its ability to compete effectively in the evolving PRC general health and wellness market, its ability to manage the growth of its business and expansion plans, its ability to achieve or maintain profitability in the future, its ability to control the risks associated with its pharmaceutical retail and wholesale businesses, and the Company's ability to meet the standards necessary to maintain listing of its ADSs on the Nasdaq Global Market, including its ability to cure any non-compliance with Nasdaq's continued listing criteria. Further information regarding these and other risks, uncertainties or factors is included in the Company's filings with the U.S. Securities and Exchange Commission. All information provided in this press release is as of the date of this press release, and 111 does not undertake any obligation to update any forward-looking statement as a result of new information, future events or otherwise, except as required under applicable law.

 

About 111, Inc.

 

111, Inc. (NASDAQ: YI) ("111" or the "Company") is a leading tech-enabled healthcare platform company committed to reshaping the value chain of healthcare industry by digitally empowering the upstream and downstream in China. The Company provides consumers with better access to pharmaceutical products and healthcare services directly through its online retail pharmacy, 1 Pharmacy, and indirectly through its offline virtual pharmacy network. The Company also offers online healthcare services through its internet hospital, 1 Clinic, which provides consumers with cost-effective and convenient online consultation, electronic prescription service, and patient management service. In addition, the Company's online platform, 1 Medicine, serves as a one-stop shop for pharmacies to source a vast selection of pharmaceutical products. With the largest virtual pharmacy network in China, 111 enables offline pharmacies to better serve their customers with cloud-based services. 111 also provides an omni-channel drug commercialization platform to its strategic partners, which includes services such as digital marketing, patient education, data analytics, and pricing monitoring.

 

For more information on 111, please visit: http://ir.111.com.cn/.

 

For more information, please contact:

 

111, Inc.  

Investor Relations  

Email: ir@111.com.cn

 

111, Inc.  

Media Relations   

Email: press@111.com.cn 

Phone: +86-021-2053 6666 (China)

 

7

 

 

111, Inc. 

UNAUDITED CONDENSED CONSOLIDATED BALANCE SHEETS 

(In thousands, except for share and per share data)

 

  As of As of
  December 31, 2024 December 31, 2025
  RMB     RMB   US$
ASSETS            
Current assets:            
Cash and cash equivalents 462,289     510,967   73,067
Restricted cash 56,043     50,337   7,198
Short-term investments -     50,031   7,154
Accounts receivable, net 413,101     259,686   37,135
Notes receivable 78,827     58,617   8,382
Inventories 1,387,403     998,465   142,779
Prepayments and other current assets 251,994     196,756   28,136
Total current assets 2,649,657     2,124,859   303,851
Property and equipment, net 32,903     21,108   3,018
Intangible assets, net 1,437     868   124
Long-term investments -      -    -
Other non-current assets 14,682     9,285   1,328
Operating lease right-of-use assets 89,071     44,122   6,309
Total assets 2,787,750     2,200,242   314,630
             
LIABILITIES, MEZZANINE EQUITY AND SHAREHOLDERS' DEFICIT            
Current liabilities:            
Short-term borrowings 160,981     187,631   26,831
Accounts payable 1,721,425     1,282,368   183,376
Accrued expense and other current liabilities 460,173     483,676   69,164
Total current liabilities 2,342,579     1,953,675   279,371
Long-term operating lease liabilities 55,448     29,965   4,285
Other non-current liabilities 8,961     2,181   312
Total liabilities 2,406,988     1,985,821   283,968
             
MEZZANINE EQUITY            
Redeemable non-controlling interests 1,038,914     935,917   133,834
             
SHAREHOLDERS' DEFICIT            
Ordinary shares Class A 33     34   5
Ordinary shares Class B 25     25   3
Treasury shares (5,887)     (5,887)   (842)
Additional paid-in capital 3,172,820     3,181,343   454,926
Accumulated deficit (3,883,992)     (3,950,384)   (564,897)
Accumulated other comprehensive income 74,357     72,635   10,387
Total shareholders' deficit (642,644)     (702,234)   (100,418)
Non-controlling interest (15,508)     (19,262)   (2,754)
Total deficit (658,152)     (721,496)   (103,172)
Total liabilities, mezzanine equity and deficit 2,787,750     2,200,242   314,630

 

8

 

 

111, Inc. 

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS 

(In thousands, except for share and per share data)

 

 

 

For the three months ended December 31, 

For the year ended December 31, 

 

2024 

2025 

2024 

2025 

 

RMB 

RMB 

US$ 

RMB 

RMB 

US$ 

Net revenues

3,847,775 

2,820,164 

403,278 

14,401,249 

12,556,023 

1,795,488

Operating costs and expenses:            
 Cost of products sold (3,645,293) (2,655,268) (379,698) (13,572,020) (11,832,617) (1,692,042)
 Fulfillment expenses (104,476) (74,058) (10,590) (381,035) (345,222) (49,366)
 Selling and marketing expenses (76,173) (62,746) (8,973) (313,897) (258,643) (36,985)
 General and administrative expenses (20,160) (18,031) (2,578) (70,907) (69,459) (9,933)
 Technology expenses (15,410) (14,769) (2,112) (69,635) (60,391) (8,636)
 Other operating income, net

6,418 

4,387 

627 

8,359 

7,932 

1,134

Total operating costs and expenses

(3,855,094)

(2,820,485)

(403,324)

(14,399,135)

(12,558,400)

(1,795,828)

(Loss) Income from operations (7,319) (321) (46) 2,114 (2,377) (340)
 Interest income 1,467 932 133 7,041 3,885 556
 Interest expense (5,264) (11,329) (1,620) (28,331) (35,572) (5,087)
 Foreign exchange (loss) gain (949) 190 27 (909) 480 69
 Other (loss) income, net

(479)

4,039

578

(595)

11,082

1,585

Loss before income taxes (12,544) (6,489) (928) (20,680) (22,502) (3,217)
 Income tax expense

(3)

-

-

(96)

(13)

(2)

Net loss (12,547) (6,489) (928) (20,776) (22,515) (3,219)
Net loss attributable to non-controlling interest 8,829 209 30 8,398 4,094 585
Net loss attributable to redeemable non-controlling interest 824 316 45 1,992 1,106 158
Adjustment attributable to redeemable non-controlling interest

(16,947)

(10,257)

(1,467)

(54,357)

(49,077)

(7,018)

Net loss attributable to ordinary shareholders

(19,841)

(16,221)

(2,320)

(64,743)

(66,392)

(9,494)

Other comprehensive loss            
 Unrealized (loss) gain of available-for-sale securities, (320) 677 97 1,074 677 97
 Realized gain (loss) of available-for-sale debt securities 321 (646) (92) (1,217) (646) (92)
 Foreign currency translation adjustments

1,754

(441)

(63)

1,986

(1,753)

(251)

Comprehensive loss

(18,086)

(16,631)

(2,378)

(62,900)

(68,114)

(9,740)

Loss per ADS:            
 Basic and diluted

(2.20)

(1.80)

(0.20)

(7.60)

(7.60)

(1.00)

Weighted average number of shares used in computation of loss per share            
 Basic and diluted

172,757,611 

175,251,218 

175,251,218 

171,835,632 

174,026,392 

174,026,392 

 

9

 

 

111, Inc.

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(In thousands)

 

 

 

For the three months ended December 31, 

For the year ended December 31, 

 

2024 

2025 

2024 

2025 

  RMB RMB US$ RMB RMB US$
             
Net cash (used in) provided by operating activities (48,547) 29,871 4,271 263,016 119,142 17,036
Net cash provided by (used in) investing activities 37,517 (22,438) (3,208) 37,376 (53,723) (7,681)
Net cash (used in) provided by financing activities (35,783) 26,561 3,797 (406,236) (21,194) (3,031)
Effect of exchange rate changes on cash and cash equivalents, and restricted cash

734

(239)

(34)

628

(1,253)

(179)

Net (decrease) increase in cash and cash equivalents, and restricted cash

(46,079)

33,755

4,826

(105,216)

42,972

6,145

Cash and cash equivalents, and restricted cash at the beginning of the period

564,411

527,549

75,439

623,548

518,332

74,120

Cash and cash equivalents, and restricted cash at the end of the period

518,332 

561,304 

80,265 

518,332 

561,304 

80,265

 

10

 

 

111, Inc.

Unaudited Reconciliation of GAAP and Non-GAAP Results

(In thousands, except for share and per share data)

 

 

 

For the three months ended December 31,

For the year ended December 31,

 

2024

2025

2024

2025

 

RMB

RMB

US$

RMB

RMB

US$

             
(Loss) Income from operations (7,319) (321) (46) 2,114 (2,377) (340)
Add: Share-based compensation expenses

5,027

 

544

 

78

 

20,149

 

10,047

 

1,437

 

Non-GAAP (loss) income from operations

(2,292)

223

32

22,263

7,670

1,097

             
Net loss (12,547) (6,489) (928) (20,776) (22,515) (3,219)
Add: Share-based compensation expenses, net of tax 5,027 544 78 20,149 10,047 1,437
Non-GAAP net loss (7,520) (5,945) (850) (627) (12,468) (1,782)
             
Net loss attributable to ordinary shareholders (19,841) (16,221) (2,320) (64,743) (66,392) (9,494)
Add: Share-based compensation expenses, net of tax

5,027

 

544

 

78

 

20,149

 

10,047

 

1,437

 

Non-GAAP net loss attributable to ordinary shareholders

(14,814)

(15,677)

(2,242)

(44,594)

(56,345)

(8,057)

             
Loss per ADS (6): Basic and diluted (2.20) (1.80) (0.20) (7.60) (7.60) (1.00)
Add: Share-based compensation expenses per ADS (6), net of tax

0.60

 

0.00

 

0.00

 

2.40

 

1.20

 

0.20

 

Non-GAAP loss per ADS (6)

(1.60)

(1.80)

(0.20)

(5.20)

(6.40)

(0.80)

 

(6) Every one ADS represents twenty Class A ordinary shares.

 

11

FAQ

How did 111, Inc. (YI) perform financially in full-year 2025?

111, Inc. generated net revenues of RMB12.6 billion in 2025, down 12.8% from 2024. Operating costs declined at the same rate, and non-GAAP income from operations was RMB7.7 million, showing the core business was slightly profitable despite lower sales.

What were 111, Inc.’s key fourth quarter 2025 financial results?

In Q4 2025, 111, Inc. reported net revenues of RMB2.8 billion, a 26.7% year-over-year decline. Loss from operations narrowed sharply to RMB0.3 million, and non-GAAP income from operations turned positive at RMB0.2 million, reflecting improved operating efficiency.

How is 111, Inc. changing its business model with the warehouse partnership strategy?

The company divested 100% equity interests in several subsidiaries and shifted to a warehouse partnership model. These facilities now act as fulfillment partners, generating recurring commission income for 111, while reducing operational and capital burdens and supporting gross margin expansion, particularly in its B2B business.

What is the status of 111, Inc.’s liquidity and cash position at the end of 2025?

As of December 31, 2025, 111, Inc. held RMB611.3 million in cash, cash equivalents, restricted cash and short-term investments, up from RMB518.3 million a year earlier. The company also delivered RMB119.1 million in positive operating cash flow during 2025.

How much does 111, Inc. owe to investors in 1 Pharmacy Technology and what repayments were made?

A total of RMB1.12 billion related to investors in 1 Pharmacy Technology is included in redeemable non-controlling interests and accrued liabilities. 111, Inc. reached agreements to reschedule repayments and paid approximately RMB189.0 million to these investors in February 2026.

Did 111, Inc. achieve profitability on a net income basis in 2025?

111, Inc. remained loss-making on a net basis in 2025, recording a net loss of RMB22.5 million, compared with RMB20.8 million in 2024. Non-GAAP net loss widened to RMB12.5 million, reflecting adjustments mainly for share-based compensation expenses.

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