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Insmed Inc Financials

INSM
FY2025 annual
Revenue $606.4M +66.7% YoY
Net Income -$1.3B -39.7% YoY
EPS (Diluted) -$6.42 -15.3% YoY
Free Cash Flow -$967.6M -37.1% YoY
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Insmed Inc (INSM) reported $606.4M in revenue for fiscal year 2025, up 66.7% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI INSM FY2025

Revenue growth is real, but Insmed still operates as a capital-funded builder because research and commercialization spending outrun gross profit.

From FY2023 to FY2025, revenue increased 98.7% but free cash flow burn deepened 76.1%, showing that scale has not yet translated into self-funding. In FY2025, R&D plus SG&A consumed $1.47B against $483M of gross profit, so the operating model still depends on external capital to support both development and commercialization.

FY2025 looks less debt-heavy than FY2024: long-term debt fell to $541M from $1.10B. But that repair came alongside financing inflows of $954M and a larger share count, so the stronger equity base was funded from outside rather than earned through operations.

The encouraging part is that gross margin stayed near 80.0% even as revenue moved past $600M, which suggests the product itself is not the source of the losses. The drag is below gross profit: selling costs, research spend, and growing receivables and inventory show a business building infrastructure faster than current sales can absorb.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 48 / 100
Financial Health Score 48/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Insmed Inc's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
29
Dilution
33
R&D Intensity
74
Revenue Progress
83
Burn Trend
21
Balance Sheet
49
Altman Z-Score Safe
6.89

Insmed Inc scores 6.89, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($28.5B) relative to total liabilities ($1.5B). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Neutral
4/9

Insmed Inc passes 4 of 9 financial strength tests. 1 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Insmed Inc reported a net loss of $1.3B while operations used $935.0M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Insmed Inc reported an operating loss of $1.2B against $83.8M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$606.4M
YoY+66.7%
5Y CAGR+29.8%

Insmed Inc generated $606.4M in revenue in fiscal year 2025. This represents an increase of 66.7% from the prior year.

EBITDA
-$1.2B
YoY-42.0%

Insmed Inc's EBITDA was -$1.2B in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 42.0% from the prior year.

Net Income
-$1.3B
YoY-39.7%

Insmed Inc reported -$1.3B in net income in fiscal year 2025. This represents a decrease of 39.7% from the prior year.

EPS (Diluted)
-$6.42
YoY-15.3%

Insmed Inc earned -$6.42 per diluted share (EPS) in fiscal year 2025. This represents a decrease of 15.3% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$967.6M
YoY-37.1%

Insmed Inc recorded an outflow of $967.6M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents a decrease of 37.1% from the prior year.

Cash & Debt
$510.4M
YoY-8.0%
5Y CAGR-0.9%
10Y CAGR+6.1%

Insmed Inc held $510.4M in cash against $541.0M in long-term debt as of fiscal year 2025.

Shares Outstanding
216M
YoY+19.1%
5Y CAGR+16.0%
10Y CAGR+13.3%

Insmed Inc had 216M shares outstanding in fiscal year 2025. This represents an increase of 19.1% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Gross Margin
79.7%
YoY+3.3pp
5Y CAGR+4.0pp

Insmed Inc's gross margin was 79.7% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is up 3.3 percentage points from the prior year.

Return on Equity
-172.8%
YoY+147.4pp

Insmed Inc's ROE was -172.8% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 147.4 percentage points from the prior year.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$771.1M
YoY+28.9%
5Y CAGR+33.6%
10Y CAGR+26.4%

Insmed Inc invested $771.1M in research and development in fiscal year 2025. This represents an increase of 28.9% from the prior year.

Capital Expenditures
$32.6M
YoY+48.5%
5Y CAGR+39.2%
10Y CAGR+25.2%

Insmed Inc invested $32.6M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 48.5% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

INSM Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

INSM annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Revenue$1.1B$606.4M+66.7%$363.7M+19.2%$305.2M+24.4%$245.4M+30.2%$188.5M+14.6%$164.4M+20.5%$136.5M+1287.6%$9.8M$0$0$0N/A$11.5M$0-100.0%$4.4M
Cost of Revenue$188.2M$122.9M+43.4%$85.7M+30.8%$65.6M+19.0%$55.1M+24.9%$44.2M+10.7%$39.9M+64.7%$24.2M+899.3%$2.4M$0$0N/AN/AN/AN/AN/A
Gross Profit$949.4M$483.5M+73.9%$278.0M+16.0%$239.6M+26.0%$190.2M+31.8%$144.3M+15.9%$124.5M+10.9%$112.3M+1414.5%$7.4M$0$0N/AN/AN/AN/AN/A
R&D Expenses$860.8M$771.1M+28.9%$598.4M+4.8%$571.0M+43.6%$397.5M+45.7%$272.7M+50.6%$181.2M+37.5%$131.7M-9.3%$145.3M+32.4%$109.7M-10.6%$122.7M+65.2%$74.3M+31.9%$56.3M+27.1%$44.3M+48.7%$29.8M+4.0%$28.6M
SG&A Expenses$893.6M$701.2M+52.1%$461.1M+33.9%$344.5M+29.6%$265.8M+13.5%$234.3M+15.1%$203.6M-3.4%$210.8M+25.3%$168.2M+112.5%$79.2M+56.2%$50.7M+17.3%$43.2M+39.1%$31.1M+39.7%$22.2M+75.7%$12.7M+9.8%$11.5M
Operating Income-$840.6M-$1.2B-42.0%-$878.3M-23.8%-$709.6M-55.2%-$457.3M-21.9%-$375.1M-41.4%-$265.2M-12.7%-$235.2M+23.5%-$307.3M-62.7%-$188.9M-9.0%-$173.4M-47.6%-$117.5M-34.5%-$87.4M-58.8%-$55.0M-29.6%-$42.4M+31.2%-$61.7M
Interest Expense$81.3M$83.8M-1.3%$84.9M+3.9%$81.7M+208.9%$26.4M-34.7%$40.5M+36.9%$29.6M+6.7%$27.7M+8.8%$25.5M+329.9%$5.9M+69.4%$3.5M+21.1%$2.9M+19.6%$2.4M+0.1%$2.4M+216.1%$763K+7530.0%$10K
Income Tax$6.2M$5.0M+35.6%$3.7M+45.1%$2.6M+84.7%$1.4M+178.7%-$1.8M-225.4%$1.4M+80.4%$777K+286.6%$201K+173.9%-$272K-377.6%$98K+105.0%-$2.0M+81.1%-$10.4M-753.6%-$1.2M$0$0
Net Income-$875.3M-$1.3B-39.7%-$913.8M-21.9%-$749.6M-55.7%-$481.5M-10.8%-$434.7M-47.8%-$294.1M-15.6%-$254.3M+21.6%-$324.3M-68.3%-$192.6M-9.3%-$176.3M-49.2%-$118.2M-49.3%-$79.2M-41.2%-$56.1M-35.5%-$41.4M+30.7%-$59.7M
EPS (Diluted)-$6.42-15.3%-$5.57-4.3%-$5.34-36.6%-$3.91-0.8%-$3.88-28.9%-$3.010.0%-$3.01N/AN/AN/AN/AN/AN/AN/A-$2.95

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

INSM Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

INSM annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Total Assets$2.3B+11.8%$2.0B+52.3%$1.3B-19.7%$1.7B+33.2%$1.2B+56.2%$796.2M+7.3%$742.3M+22.8%$604.6M+30.8%$462.0M+94.2%$238.0M-33.3%$356.6M+54.4%$230.9M+30.8%$176.5M+14.9%$153.6M+9.8%$139.8M
Current Assets$1.8B+10.6%$1.6B+74.5%$929.1M-27.0%$1.3B+52.1%$837.0M+34.4%$622.9M+12.2%$555.2M+7.0%$518.9M+33.3%$389.4M+131.3%$168.4M-41.5%$288.1M+74.9%$164.7M+41.8%$116.2M+24.1%$93.6M+20.9%$77.4M
Cash & Equivalents$510.4M-8.0%$555.0M+15.1%$482.4M-55.1%$1.1B+49.8%$716.8M+34.5%$532.8M+9.3%$487.4M-1.5%$495.1M+29.9%$381.2M+134.4%$162.6M-42.5%$282.9M+77.7%$159.2M+39.8%$113.9M+25.5%$90.8M+511.4%$14.8M
Inventory$132.1M+34.0%$98.6M+18.4%$83.2M+19.1%$69.9M+4.3%$67.0M+35.1%$49.6M+75.2%$28.3M+302.6%$7.0M$0N/AN/AN/AN/AN/AN/A
Accounts Receivable$140.9M+170.8%$52.0M+26.3%$41.2M+38.6%$29.7M+22.0%$24.4M+47.0%$16.6M-13.9%$19.2M+248.7%$5.5M$0N/AN/AN/AN/A$0-100.0%$757K
Goodwill$136.1M0.0%$136.1M0.0%$136.1M0.0%$136.1M0.0%$136.1M$0N/AN/AN/AN/AN/AN/AN/AN/A$0
Total Liabilities$1.5B-12.3%$1.7B+4.7%$1.7B+5.9%$1.6B+88.3%$833.0M+60.1%$520.3M+8.2%$480.6M+21.3%$396.3M+292.4%$101.0M+21.0%$83.5M+86.1%$44.9M+0.5%$44.6M+34.5%$33.2M+1.5%$32.7M+487.1%$5.6M
Current Liabilities$468.9M+57.6%$297.5M+31.9%$225.6M+18.6%$190.2M+40.7%$135.2M+13.8%$118.8M+39.4%$85.2M+6.9%$79.7M+78.5%$44.7M+59.5%$28.0M+25.7%$22.3M+13.4%$19.6M+19.3%$16.5M+4.5%$15.7M+251.7%$4.5M
Long-Term Debt$541.0M-51.0%$1.1B-4.5%$1.2B+2.7%$1.1B+98.6%$566.6M+59.0%$356.3M+6.1%$335.9M+6.1%$316.6M+469.7%$55.6M+1.4%$54.8M+148.7%$22.0M-11.4%$24.9M+52.1%$16.3M+0.7%$16.2M$0
Total Equity$739.0M+158.9%$285.4M+186.0%-$331.9M-477.4%$88.0M-78.6%$410.5M+48.8%$275.9M+5.4%$261.7M+25.6%$208.3M-42.3%$361.1M+133.7%$154.5M-50.4%$311.7M+67.4%$186.2M+29.9%$143.3M+18.6%$120.9M-10.0%$134.3M
Retained Earnings-$5.6B-29.3%-$4.4B-26.5%-$3.4B-27.8%-$2.7B-19.0%-$2.3B-23.7%-$1.8B-19.1%-$1.5B-19.8%-$1.3B-33.9%-$957.9M-25.2%-$765.2M-29.9%-$589.0M-25.1%-$470.8M-20.2%-$391.6M-16.7%-$335.5M-14.1%-$294.2M

INSM Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

INSM annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Operating Cash Flow-$778.9M-$935.0M-36.7%-$683.9M-27.5%-$536.2M-33.9%-$400.4M-10.2%-$363.3M-65.6%-$219.3M+12.5%-$250.6M+2.8%-$258.0M-61.6%-$159.6M-8.8%-$146.7M-45.7%-$100.7M-56.3%-$64.4M-38.0%-$46.7M-50.5%-$31.0M-2.7%-$30.2M
Capital Expenditures$28.7M$32.6M+48.5%$21.9M+65.0%$13.3M+34.5%$9.9M+35.5%$7.3M+16.8%$6.2M-85.2%$42.3M+222.9%$13.1M+336.2%$3.0M-28.5%$4.2M+21.6%$3.5M-35.5%$5.4M+547.8%$826K+184.8%$290K-70.4%$979K
Free Cash Flow-$807.7M-$967.6M-37.1%-$705.8M-28.4%-$549.5M-33.9%-$410.3M-10.7%-$370.6M-64.3%-$225.6M+23.0%-$292.9M-8.1%-$271.1M-66.7%-$162.6M-7.8%-$150.9M-44.9%-$104.2M-49.3%-$69.8M-46.9%-$47.5M-51.7%-$31.3M-0.4%-$31.2M
Investing Cash Flow-$82.8M-$64.6M+88.9%-$583.2M-160.8%-$223.6M-546.6%-$34.6M+46.2%-$64.3M-842.3%-$6.8M+83.9%-$42.3M-185.3%-$14.8M-393.6%-$3.0M+28.5%-$4.2M-21.6%-$3.5MN/AN/A$61.5M+79.1%$34.4M
Financing Cash Flow$124.0M$954.1M-28.9%$1.3B+696.1%$168.4M-78.8%$793.3M+29.5%$612.5M+126.0%$271.0M-5.0%$285.3M-26.2%$386.7M+1.5%$381.1M+1142.4%$30.7M-86.5%$227.8MN/AN/A$45.4M+90948.0%-$50K

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

INSM Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

INSM annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Gross Margin79.7%+3.3pp76.4%-2.1pp78.5%+1.0pp77.5%+1.0pp76.6%+0.8pp75.8%-6.5pp82.3%+6.9pp75.4%N/AN/AN/AN/AN/AN/AN/A
Operating Margin-205.6%-241.5%-232.5%-186.4%-199.0%-161.3%-172.4%-3124.9%N/AN/AN/AN/A-478.4%N/A-1397.3%
Net Margin-210.5%-251.2%-245.6%-196.3%-230.6%-178.9%-186.4%-3297.2%N/AN/AN/AN/A-487.6%N/A-1350.8%
Return on Equity-172.8%+147.4pp-320.2%N/A-547.5%-441.6pp-105.9%+0.7pp-106.6%-9.4pp-97.2%+58.5pp-155.7%-102.3pp-53.4%+60.8pp-114.1%-76.2pp-37.9%+4.6pp-42.5%-3.4pp-39.1%-4.9pp-34.2%+10.2pp-44.4%
Return on Assets-56.4%-11.3pp-45.1%+11.2pp-56.4%-27.3pp-29.1%+5.9pp-34.9%+2.0pp-36.9%-2.7pp-34.3%+19.4pp-53.6%-11.9pp-41.7%+32.4pp-74.1%-40.9pp-33.1%+1.1pp-34.3%-2.5pp-31.8%-4.8pp-26.9%+15.7pp-42.7%
Current Ratio3.83-1.6x5.45+1.3x4.12-2.6x6.69+0.5x6.19+0.9x5.24-1.3x6.510.0x6.51-2.2x8.72+2.7x6.02-6.9x12.94+4.6x8.39+1.3x7.06+1.1x5.94-11.3x17.29
Debt-to-Equity0.73-3.1x3.87N/A12.79+11.4x1.38+0.1x1.290.0x1.28-0.2x1.52+1.4x0.15-0.2x0.35+0.3x0.07-0.1x0.130.0x0.110.0x0.13+0.1x0.00
FCF Margin-159.5%-194.1%-180.1%-167.2%-196.6%-137.2%-214.6%-2756.2%N/AN/AN/AN/A-413.0%N/A-706.0%

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Insmed Inc's annual revenue?

Insmed Inc (INSM) reported $606.4M in total revenue for fiscal year 2025. This represents a 66.7% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Insmed Inc's revenue growing?

Insmed Inc (INSM) revenue grew by 66.7% year-over-year, from $363.7M to $606.4M in fiscal year 2025.

Is Insmed Inc profitable?

No, Insmed Inc (INSM) reported a net income of -$1.3B in fiscal year 2025.

Insmed Inc (INSM) reported diluted earnings per share of -$6.42 for fiscal year 2025. This represents a -15.3% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Insmed Inc (INSM) had EBITDA of -$1.2B in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Insmed Inc (INSM) had $510.4M in cash and equivalents against $541.0M in long-term debt.

Insmed Inc (INSM) had a gross margin of 79.7% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Insmed Inc (INSM) has a return on equity of -172.8% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Insmed Inc (INSM) recorded an outflow of $967.6M in free cash flow during fiscal year 2025. This represents a -37.1% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Insmed Inc (INSM) recorded an outflow of $935.0M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Insmed Inc (INSM) had $2.3B in total assets as of fiscal year 2025, including both current and long-term assets.

Insmed Inc (INSM) invested $32.6M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Insmed Inc (INSM) invested $771.1M in research and development during fiscal year 2025.

Insmed Inc (INSM) had 216M shares outstanding as of fiscal year 2025.

Insmed Inc (INSM) had a current ratio of 3.83 as of fiscal year 2025, which is generally considered healthy.

Insmed Inc (INSM) had a debt-to-equity ratio of 0.73 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Insmed Inc (INSM) had a return on assets of -56.4% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Insmed Inc (INSM) had $510.4M in cash against an annual operating cash burn of $935.0M. This gives an estimated cash runway of approximately 7 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Insmed Inc (INSM) has an Altman Z-Score of 6.89, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Insmed Inc (INSM) has a Piotroski F-Score of 4 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Insmed Inc (INSM) reported a net loss of $1.3B while operations used $935.0M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Insmed Inc (INSM) reported an operating loss of $1.2B against $83.8M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Insmed Inc (INSM) scores 48 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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