STOCK TITAN

Centessa Pharmaceuticals Plc SEC Filings

CNTA NASDAQ

Welcome to our dedicated page for Centessa Pharmaceuticals Plc SEC filings (Ticker: CNTA), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

SEC documents for a clinical-stage biotech like Centessa Pharmaceuticals can feel like navigating a maze of scientific jargon and risk factors. Pipeline updates on orexin agonists, the LockBody immuno-oncology platform, and critical cash-runway disclosures are scattered across hundreds of pages. Missing one footnote could mean overlooking a trial halt or royalty obligation.

Stock Titan’s AI decodes every Centessa Pharmaceuticals quarterly earnings report 10-Q filing and annual report 10-K simplified, surfacing what matters—R&D spend by program, milestone payments, and liquidity outlook. Need to see Centessa Pharmaceuticals insider trading Form 4 transactions? You’ll also get Centessa Pharmaceuticals Form 4 insider transactions real-time as they post, while side-by-side comparisons help you understand Centessa Pharmaceuticals SEC filings explained simply. Even sudden announcements, like the 8-K material events explained when SerpinPC was discontinued, land on your dashboard seconds after they hit EDGAR.

Investors use these insights to:

  • Monitor Centessa Pharmaceuticals executive stock transactions Form 4 before key data read-outs
  • Track progress of ORX750 and LB101 across filings without sifting through appendices
  • Compare quarter-over-quarter spending using understanding Centessa Pharmaceuticals SEC documents with AI
  • Review the proxy statement executive compensation details in plain English

Whether you’re preparing a valuation model or answering, “How do I read Centessa Pharmaceuticals earnings report filing analysis?”, Stock Titan delivers the context. Real-time updates, AI-powered summaries, and historical documents ensure you never miss a disclosure again.

Rhea-AI Summary

Centessa (NASDAQ:CNTA) Form 4 reports that Chief Business Officer Gregory M. Weinhoff exercised 10,000 options at $3.85 and immediately sold the same 10,000 ordinary shares on 06/25/2025 through a Rule 10b5-1 plan.

The shares were disposed at a weighted-average price of $13.8642, yielding roughly $139 k in gross proceeds and an implied ~$10 per-share spread. After the transactions he still owns 122,279 ordinary shares (≈8 % reduction versus post-exercise balance) and 65,000 unexercised options. The sale exceeds the 5 % materiality threshold for insider trades, making the activity noteworthy for investors tracking executive sentiment.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
insider
-
Rhea-AI Summary

Centessa Pharmaceuticals (NASDAQ: CNTA) Form 4 shows General Counsel Iqbal J. Hussain exercised 12,000 stock options at $5.84 and immediately sold the same number of ordinary shares at a weighted-average $14.02 on 06/24/2025 under a Rule 10b5-1 plan.

Post-transaction, Hussain’s direct ownership declined by ~10% to 105,386 shares; he also holds 5,500 shares indirectly and 291,559 unexercised options.

  • Gross sale proceeds ≈ $168.2 K.
  • Sale represents >5% of insider’s pre-sale direct holdings, meeting materiality threshold.
  • No impact on share count or dilution.

Insider selling by a senior legal officer can be viewed as a potential sentiment headwind, though execution under a pre-arranged 10b5-1 plan mitigates timing concerns.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
insider
-
Rhea-AI Summary

Centessa (NASDAQ:CNTA) filed a Form 4 showing that President, Orexin Program Mario Alberto Accardi exercised options for 15,000 ordinary shares at $3.85 and immediately sold the same 15,000 shares at $14.00 on 06/24/2025 under a Rule 10b5-1 plan.

The transaction generated roughly $210 k in gross proceeds and reduced his direct holdings by 6.5% to 216,485 shares; he still holds 15,300 vested options. Because the sale exceeds 5% of his prior stake, it meets materiality thresholds for insider activity that investors track for sentiment shifts.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
insider
Rhea-AI Summary

Centessa Pharmaceuticals (NASDAQ: CNTA) submitted a Form 144 notice covering the proposed sale of 10,000 common shares—approximately $140,000 in aggregate market value—through UBS Financial Services on or around 26 June 2025. The filing lists 133,618,774 shares outstanding, so the planned sale represents less than 0.01 % of the float.

The same account holder reported three earlier open‐market sales during the past three months: 10,000 shares on 25 March 2025 for $163,386, 11,742 shares on 25 April 2025 for $159,857, and 10,000 shares on 27 May 2025 for $128,225. Combined with the new notice, gross proceeds from the four transactions total roughly $591,000. No additional financial statements, risk factors, or business updates were provided in this routine disclosure.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
other
-
Rhea-AI Summary

A Form 144 filing from Centessa Pharmaceuticals indicates a proposed sale of 15,000 shares of common stock through UBS Financial Services. The shares have an aggregate market value of $210,000, with the sale planned for June 24, 2025 on the Nasdaq exchange.

The securities were acquired through the exercise of stock options from the issuer on June 24, 2025, with payment made in cash. The total outstanding shares of the company are 133,618,774.

Key details:

  • Share price implied by filing: $14.00 per share
  • No other securities sales reported by the seller in the past 3 months
  • Transaction represents approximately 0.011% of total outstanding shares
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
other
-
Rhea-AI Summary

Director Arjun Goyal of Centessa Pharmaceuticals was granted 40,000 stock options on June 20, 2025. The options have the following key terms:

  • Exercise price set at $12.43 per share
  • Expiration date of June 20, 2035
  • Vesting occurs at earlier of: - First anniversary of grant date - Next annual shareholder meeting
  • Options convert to ordinary shares (which may be represented as American Depositary Shares)
  • Vesting conditional on continued service as director

This Form 4 filing, signed by attorney-in-fact Iqbal Hussain, represents a standard director compensation equity grant, suggesting continued commitment to aligning director interests with shareholders through long-term equity incentives.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
insider
Rhea-AI Summary

Form 4 filing reveals that Mary Lynne Hedley, Director at Centessa Pharmaceuticals, was granted 40,000 share options on June 20, 2025. The stock options have an exercise price of $12.43 per share and will expire on June 20, 2035.

Key details of the option grant:

  • Vesting occurs at the earlier of: (1) first anniversary of grant date or (2) next annual shareholder meeting
  • Vesting is contingent on continued service as director
  • Options are convertible into ordinary shares, which may be represented as American Depositary Shares (1:1 ratio)
  • Direct ownership form reported

This grant appears to be part of the company's director compensation program. No other securities transactions were reported in this filing.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
insider
-
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
insider
-
Rhea-AI Summary

Form 4 filing reveals that Samarth Kulkarni, Director at Centessa Pharmaceuticals, received a stock option grant on June 20, 2025. Key details:

  • Granted 40,000 stock options to purchase ordinary shares at an exercise price of $12.43 per share
  • Options will vest in full at the earlier of: - First anniversary of grant date - Next annual shareholder meeting
  • Options expire on June 20, 2035
  • Vesting conditional on continued service as director
  • Ordinary shares may be represented by American Depositary Shares (ADS), with each ADS representing one ordinary share

This equity compensation grant aligns with standard director compensation practices and aims to align the director's interests with shareholders. The filing was signed by Iqbal Hussain as attorney-in-fact on June 24, 2025.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
insider
Rhea-AI Summary

Centessa Pharmaceuticals director Carol Stuckley received a stock option grant on June 20, 2025. The derivative securities transaction details include:

  • Granted 40,000 share options to purchase ordinary shares
  • Exercise price set at $12.43 per share
  • Options expire on June 20, 2035
  • Vesting occurs at earlier of:
    • First anniversary of grant date
    • Next annual shareholder meeting

The options are subject to continued service as director through the vesting date. Each ordinary share may be represented by one American Depositary Share (ADS). The transaction was reported via Form 4 filing with attorney-in-fact signature dated June 24, 2025.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
insider

FAQ

What is the current stock price of Centessa Pharmaceuticals Plc (CNTA)?

The current stock price of Centessa Pharmaceuticals Plc (CNTA) is $13.13 as of June 28, 2025.

What is the market cap of Centessa Pharmaceuticals Plc (CNTA)?

The market cap of Centessa Pharmaceuticals Plc (CNTA) is approximately 1.7B.

What is Centessa Pharmaceuticals' business model?

Centessa employs an asset-centric R&D model, where each program operates as a subsidiary supported by centralized resources, enabling efficient and focused drug development.

What are Centessa's key therapeutic areas?

Centessa focuses on sleep-wake disorders, immuno-oncology, and previously hemophilia, with innovative programs like orexin receptor agonists and the LockBody® platform.

What is the purpose of Centessa's orexin agonist program?

The orexin agonist program aims to develop therapies for narcolepsy, idiopathic hypersomnia, and excessive daytime sleepiness by targeting the underlying pathophysiology of orexin neuron loss.

What is the LockBody technology platform?

The LockBody platform is designed to selectively target the tumor microenvironment in cancer, enhancing efficacy while minimizing systemic toxicity.

Why did Centessa discontinue its SerpinPC program?

Centessa discontinued SerpinPC to prioritize resources for its orexin agonist program, aligning with its focus on high-potential assets and evolving market needs.

What makes Centessa Pharmaceuticals unique?

Centessa's asset-centric R&D model, innovative orexin agonist program, and LockBody technology platform set it apart in the competitive biopharmaceutical landscape.

What is ORX750?

ORX750 is a highly potent and selective orexin receptor 2 (OX2R) agonist in clinical trials for narcolepsy, idiopathic hypersomnia, and other sleep-wake disorders.

What is Centessa's financial position?

Centessa has a cash runway extending into mid-2027, supporting its clinical development plans and multiple potential value-creating milestones.

What are Centessa's competitive advantages?

Centessa's competitive advantages include its asset-centric R&D model, differentiated orexin agonist pipeline, and the innovative LockBody platform for immuno-oncology.

What is Centessa's mission?

Centessa's mission is to deliver transformational medicines that improve patient outcomes and establish new standards of care.
Centessa Pharmaceuticals Plc

NASDAQ:CNTA

CNTA Rankings

CNTA Stock Data

1.74B
118.69M
1.29%
97.12%
4.14%
Biotechnology
Pharmaceutical Preparations
Link
United Kingdom
ALTRINCHAM, CHESHIRE