Every Form 4 that Sol-Gel Technologies Ltd. (SLGL) has filed with the SEC in the last 12 months is listed below, newest first, and each one links through to the document itself with the summary and the scores our analysis gives it.
A Form 4 covers the transactions officers, directors and large holders report, so if you follow SLGL and want that one kind of document rather than the whole filing history, this is the page to keep. The company's other filings, of every form, are on the full SLGL filings page.
Sol-Gel Technologies Ltd. (SLGL) reports that Opaleye Management Inc., a ten percent owner, indirectly purchased 3,124 ordinary shares in open-market transactions on September 10–11, 2026 through Opaleye, L.P. A separately managed account for which Opaleye Management acts as portfolio manager held 15,000 ordinary shares as of September 10, 2026. Opaleye Management may be deemed to beneficially own these securities but disclaims beneficial ownership except to the extent of its pecuniary interest.
Sol-Gel Technologies Ltd. (SLGL) reports that Opaleye Management Inc., a ten percent owner, indirectly purchased additional ordinary shares over several days in September 2026. Through Opaleye, L.P., it bought a total of 9,976 ordinary shares between September 4 and September 9, 2026 at prices generally around $68–$70 per share, including weighted-average purchases with disclosed price ranges. Opaleye Management Inc. reports these positions as indirectly held and disclaims beneficial ownership beyond its pecuniary interest, and no Rule 10b5-1 trading plan is reported.
Sol-Gel Technologies Ltd. (SLGL) had insider activity reported by Opaleye Management Inc., a more-than-10% owner. On September 1–2, 2026, entities it manages purchased 1,683 ordinary shares of Sol-Gel in open-market or private transactions at prices around $68.94–$69.52 per share, held indirectly through a fund and a managed account. A managed account associated with Opaleye Management Inc. held 15,000 ordinary shares after these transactions. No Rule 10b5-1 trading plan is reported, and Opaleye Management Inc. disclaims beneficial ownership beyond its pecuniary interest.
Sol-Gel Technologies Ltd. (SLGL) reports that large shareholder Opaleye Management Inc. filed a Form 4 showing open-market purchases of 40,330 ordinary shares on August 28 and 31, 2026. The shares were acquired indirectly through Opaleye, L.P. and a separately managed account, with 15,000 shares reported as held in the managed account. Certain trades used weighted average prices within disclosed ranges, and Opaleye Management Inc. disclaims beneficial ownership except to the extent of its pecuniary interest.
Opaleye Management Inc., a more than ten percent owner of Sol-Gel Technologies Ltd., reported an indirect open-market purchase of 951 Ordinary Shares on 2026-08-12 at $71.50 per share, held via Opaleye, L.P. Following this trade, that fund’s indirect holdings in Sol-Gel total 494,887 Ordinary Shares. A separate line reports 15,000 Ordinary Shares held in a managed account. Opaleye Management Inc. states that it may be deemed to beneficially own these securities through its roles with the fund and managed account, but disclaims beneficial ownership except to the extent of its pecuniary interest.
Opaleye Management Inc., a ten percent owner of Sol-Gel Technologies Ltd., reported net insider buying. Through Opaleye, L.P., it purchased 775 ordinary shares on July 13 and 920 shares on July 14, 2026, in open‑market transactions at weighted‑average prices of $73.89 and $73.43 per share, executed in multiple trades within disclosed ranges of $73.34–$73.50 and $73.75–$73.95. Following these trades, Opaleye, L.P. holds 493,936 shares, and a separately managed account overseen by Opaleye Management holds 15,000 shares. Opaleye Management disclaims beneficial ownership beyond its pecuniary interest.
Opaleye Management Inc., a more than ten percent owner of Sol-Gel Technologies Ltd., reported open-market purchases of the company’s ordinary shares. On July 8, 2026, an affiliated fund bought 300 shares at $73.69 per share, and on July 10, 2026 it bought an additional 229 shares at $73.95 per share. After these trades, the fund held 492,241 shares indirectly attributed to Opaleye Management Inc., and a separately managed account associated with it held 15,000 shares, with Opaleye Management Inc. disclaiming beneficial ownership beyond its pecuniary interest.
Opaleye Management Inc., a more than ten percent owner of Sol-Gel Technologies Ltd., reported additional indirect purchases of the company’s ordinary shares. Through Opaleye, L.P., it completed open-market purchases totaling 1,712 shares at prices ranging from $71.96 to $71.99 per share. After these trades, Opaleye, L.P. held 491,712 ordinary shares, while a separately managed account overseen by Opaleye Management held 15,000 shares, both positions being reported as indirect holdings. Opaleye Management disclaims beneficial ownership of these shares beyond any pecuniary interest.
Sol-Gel Technologies Ltd. reported that entities managed by Opaleye Management Inc. made an open-market purchase of 1,563 ordinary shares on May 20, 2026 at a weighted average price of $64.4349 per share, with individual trades between $63.97 and $64.50. Following the transaction, an Opaleye-managed fund indirectly holds 490,000 shares, and a separately managed account holds 15,000 shares. Opaleye Management may be deemed to beneficially own these securities through its roles with the fund and managed account but disclaims beneficial ownership beyond its pecuniary interest.
Opaleye Management Inc., a ten percent owner of Sol-Gel Technologies Ltd., reported open-market purchases of the company’s ordinary shares through affiliated accounts. On May 12 and May 13, an affiliated fund, Opaleye, L.P., bought a total of 3,437 ordinary shares in two open-market transactions. The purchases were made at weighted average prices of $67.9833 and $66.8701 per share. After these trades, Opaleye, L.P. held 488,437 ordinary shares, while a separately managed account overseen by Opaleye Management held 15,000 ordinary shares. Opaleye Management disclaims beneficial ownership of these shares beyond its pecuniary interest.
Sol-Gel Technologies Ltd. reported insider buying by entities associated with Opaleye Management Inc., a more than ten percent owner. On March 24, 2026, Opaleye, L.P. purchased 34,665 ordinary shares at 72 per share, bringing its holdings to 485,000 shares. A separately managed account overseen by Opaleye Management bought an additional 5,000 shares at 72 per share, increasing that account’s position to 15,000 shares. Opaleye Management Inc. may be deemed to beneficially own these securities as investment manager and portfolio manager, but explicitly disclaims beneficial ownership except to the extent of its pecuniary interest.
Opaleye Management Inc., a more than ten percent owner of Sol-Gel Technologies Ltd., reported an indirect open-market purchase of 291 ordinary shares of Sol-Gel on February 13, 2026 at a price of $63.00 per share, through Opaleye, L.P.
After this transaction, Opaleye, L.P. held 450,335 ordinary shares, and a separately managed account overseen by Opaleye held 10,000 ordinary shares. Opaleye Management Inc. disclaims beneficial ownership of these shares except to the extent of its pecuniary interest.
Sol-Gel Technologies Ltd. reported an amended insider filing for Opaleye Management Inc., a more than 10% holder. Through Opaleye, L.P., a related fund, there was an open-market purchase of 100 ordinary shares at a price of 58.0000 per share on 2026-02-02.
After this trade, Opaleye, L.P. held 450,044 shares, and a separately managed account associated with Opaleye held 10,000 shares, both reported as indirect ownership. The amendment states it corrects the previously reported beneficially owned share count due to a clerical error, and Opaleye Management Inc. disclaims beneficial ownership except to the extent of its pecuniary interest.
Sol-Gel Technologies Ltd. had an insider ownership update involving entities managed by Opaleye Management Inc. On February 2, 2026, Opaleye, L.P. purchased 100 ordinary shares of Sol-Gel at $58 per share, bringing its indirectly held position to 450,944 ordinary shares. A separately managed account overseen by Opaleye Management holds an additional 10,000 ordinary shares indirectly. Opaleye Management Inc. states that it may be deemed to beneficially own these securities but disclaims beneficial ownership beyond its pecuniary interest.
Opaleye Management Inc., a 10% owner of Sol-Gel Technologies Ltd., reported an indirect open‑market purchase of 100 ordinary shares on January 27, 2026 at $57.05 per share. These shares are held by Opaleye, L.P., bringing that fund’s reported holdings to 449,944 shares. A separately managed account associated with Opaleye holds an additional 10,000 shares. Opaleye Management Inc. states it may be deemed to beneficially own these securities through its roles with the fund and managed account, but disclaims beneficial ownership except to the extent of its pecuniary interest.
Opaleye Management Inc., a 10% owner of Sol-Gel Technologies Ltd. (SLGL), reported January open-market share purchases made through affiliated investment vehicles. On January 22, 2026, Opaleye, L.P. bought 2,173 ordinary shares at a weighted average price of $56.5681 per share, and on January 23, 2026 it bought another 1,151 shares at a weighted average price of $55.9809. After these transactions, 449,844 ordinary shares were held indirectly through Opaleye, L.P., and an additional 10,000 shares were held indirectly via a separately managed account. The filing notes that prices reflect weighted averages across multiple trades within disclosed price ranges and that Opaleye Management Inc. disclaims beneficial ownership beyond its pecuniary interest.
Opaleye Management Inc., reporting as a 10% owner of Sol-Gel Technologies Ltd., disclosed a small indirect purchase of ordinary shares. On 12/12/2025, 87 ordinary shares with a par value of NIS 1.00 per share were acquired at a reported price of $40. After this transaction, 371,795 ordinary shares are held indirectly through Opaleye, L.P. and 10,000 ordinary shares are held indirectly through a separately managed account. Opaleye Management Inc. states it may be deemed to beneficially own these securities through its roles with the fund and managed account, but disclaims beneficial ownership except to the extent of its pecuniary interest.
Opaleye Management Inc. reported open market purchases of Sol-Gel Technologies Ltd. (SLGL) ordinary shares. On 11/24/2025, an affiliated fund bought 6 ordinary shares at $35.5 per share, and on 11/26/2025 it bought another 943 shares at a weighted average price of $40.00. Following these transactions, the fund is shown as beneficially owning 364,100 Sol-Gel ordinary shares, with an additional 10,000 shares held in a separately managed account. Opaleye Management Inc. states that it may be deemed to beneficially own these securities through its roles with the fund and the managed account and disclaims beneficial ownership except to the extent of its pecuniary interest.
Sol-Gel Technologies Ltd. (SLGL) director Opaleye Management Inc. reported buying additional ordinary shares. On 11/20/2025, an affiliated fund purchased 5,784 ordinary shares at a weighted average price of $35.8305 per share in multiple trades within a price range of $35.132 to $36.10. After this transaction, Opaleye Management Inc. reports indirect beneficial ownership of 363,151 ordinary shares through Opaleye, L.P. and 10,000 ordinary shares through a separately managed account. The firm states it may be deemed to beneficially own these securities as investment manager and portfolio manager, while disclaiming beneficial ownership beyond its economic interest.