Top Healthcare Stocks by Return on Equity
Top healthcare companies ranked by return on equity, latest annual filings.
What Return on Equity Means for Healthcare Companies
Return on Equity divides net income by shareholder equity. In healthcare, the ratio is most useful at mature pharmaceutical and medical device firms, where patent-protected franchises and steady cash generation produce stable mid-range figures over time. For clinical-stage biotechs the calculation often breaks down because persistent losses and accumulated deficits can push equity negative, producing ratios that carry no real information.
Why It Matters Less in Healthcare
Mature pharma Return on Equity is driven by patent-protected franchises and efficient capital deployment, which gives the ratio some interpretive value through cycles. However pipeline risk and patent cliffs can distort trend readings, and buybacks funded during peak earnings years inflate the ratio just before blockbuster products lose exclusivity. For biotech the metric is rarely meaningful because negative or near-zero equity produces mathematically odd ratios that mislead more than they inform.
What to Read Alongside
Pair Return on Equity with [Net Income](/financials/top-net-income-stocks/healthcare/) to see profitability in absolute terms, [Long-term Debt](/financials/most-indebted-stocks/healthcare/) to check how leverage is flattering the ratio, and [R&D Spending](/financials/top-rd-spending-stocks/healthcare/) to see the pipeline reinvestment intensity behind the numbers.
| # | Symbol | Company | Sector | ||
|---|---|---|---|---|---|
| 1 | MEDP | Medpace Holdings, Inc. | Healthcare | 98.27% | $14.87B |
| 2 | RIGL | Rigel Pharmaceuticals, Inc. | Healthcare | 93.75% | $0.60B |
| 3 | AMGN | Amgen Inc. | Healthcare | 89.06% | $191.53B |
| 4 | NRC | National Research Corporation | Healthcare | 82.92% | $0.41B |
| 5 | ZTS | Zoetis Inc. | Healthcare | 80.25% | $51.46B |
| 6 | LLY | Eli Lilly and Company | Healthcare | 77.78% | $828.17B |
| 7 | QTTB | Q32 Bio Inc. | Healthcare | 70.98% | $0.09B |
| 8 | PMCB | PharmaCyte Biotech, Inc. | Healthcare | 70.33% | $0.01B |
| 9 | TGTX | TG Therapeutics, Inc. | Healthcare | 69.01% | $5.64B |
| 10 | IDXX | IDEXX Laboratories, Inc. | Healthcare | 65.99% | $46.80B |
| 11 | ENLV | Enlivex Ltd. | Healthcare | 63.85% | $0.21B |
| 12 | LFMD | LifeMD, Inc. | Healthcare | 61.99% | $0.19B |
| 13 | THC | Tenet Healthcare Corporation | Healthcare | 56.09% | $17.23B |
| 14 | ZVRA | Zevra Therapeutics, Inc. | Healthcare | 53.82% | $0.63B |
| 15 | AUPH | Aurinia Pharmaceuticals Inc. | Healthcare | 49.40% | $2.13B |
| 16 | CON | Concentra Group Holdings Parent, Inc. | Healthcare | 42.31% | $2.94B |
| 17 | CRMD | CorMedix Inc. | Healthcare | 40.23% | $0.58B |
| 18 | TMDX | TransMedics Group, Inc. | Healthcare | 40.22% | $4.00B |
| 19 | ALNY | Alnylam Pharmaceuticals, Inc. | Healthcare | 39.76% | $41.32B |
| 20 | BMY | Bristol-Myers Squibb Company | Healthcare | 38.19% | $122.85B |
| 21 | XOMAP | XOMA Royalty Corporation | Healthcare | 37.78% | – |
| 22 | GILD | Gilead Sciences, Inc. | Healthcare | 37.48% | $170.84B |
| 23 | NIVF | NewGenIvf Group Limited | Healthcare | 37.10% | $0.00B |
| 24 | HCM | HUTCHMED (China) Limited | Healthcare | 36.91% | $2.71B |
| 25 | EXEL | Exelixis, Inc. | Healthcare | 36.21% | $11.40B |
| 26 | TBPH | Theravance Biopharma, Inc. | Healthcare | 35.69% | $0.89B |
| 27 | MRK | Merck & Co., Inc. | Healthcare | 34.70% | $294.09B |
| 28 | CGEN | Compugen Ltd. | Healthcare | 34.40% | $0.27B |
| 29 | RDGT | Ridgetech, Inc. | Healthcare | 34.40% | $0.00B |
| 30 | JNJ | Johnson & Johnson | Healthcare | 32.87% | $564.05B |
| 31 | ORMP | Oramed Pharmaceuticals Inc. | Healthcare | 32.07% | $0.16B |
| 32 | ACAD | ACADIA Pharmaceuticals Inc. | Healthcare | 31.86% | $3.78B |
| 33 | BDMD | Baird Medical Investment Holdings Limited | Healthcare | 31.77% | $0.06B |
| 34 | ILMN | Illumina, Inc. | Healthcare | 31.22% | $20.43B |
| 35 | SOLV | Solventum Corporation | Healthcare | 30.82% | $12.22B |
| 36 | ADMA | ADMA Biologics, Inc. | Healthcare | 30.78% | $2.56B |
| 37 | DXCM | DexCom, Inc. | Healthcare | 30.46% | $24.69B |
| 38 | NVS | Novartis AG | Healthcare | 30.00% | $289.98B |
| 39 | KROS | Keros Therapeutics, Inc. | Healthcare | 28.70% | $0.23B |
| 40 | WAT | Waters Corporation | Healthcare | 25.09% | $32.18B |
| 41 | INCY | Incyte Corporation | Healthcare | 24.90% | $19.47B |
| 42 | OGN | Organon & Co. | Healthcare | 24.87% | $2.54B |
| 43 | PDEX | Pro-Dex, Inc. | Healthcare | 24.51% | $0.17B |
| 44 | PBYI | Puma Biotechnology, Inc. | Healthcare | 23.87% | $0.38B |
| 45 | IRMD | IRADIMED CORPORATION | Healthcare | 23.76% | $1.20B |
| 46 | HIMS | Hims & Hers Health, Inc. | Healthcare | 23.73% | $6.57B |
| 47 | RMD | ResMed Inc. | Healthcare | 23.47% | $33.23B |
| 48 | EHC | Encompass Health Corporation | Healthcare | 23.22% | $10.58B |
| 49 | INVA | Innoviva, Inc. | Healthcare | 23.12% | $1.80B |
| 50 | NAGE | Niagen Bioscience, Inc. | Healthcare | 22.71% | $0.39B |
| 51 | GRDN | Guardian Pharmacy Services, Inc. | Healthcare | 22.59% | $2.42B |
| 52 | CPRX | Catalyst Pharmaceuticals, Inc. | Healthcare | 22.46% | $3.21B |
| 53 | NUTX | Nutex Health Inc. | Healthcare | 21.49% | $0.74B |
| 54 | LNTH | Lantheus Holdings, Inc. | Healthcare | 21.43% | $5.46B |
| 55 | NNNN | Anbio Biotechnology | Healthcare | 21.24% | $1.19B |
| 56 | VRTX | Vertex Pharmaceuticals Incorporated | Healthcare | 21.18% | $112.22B |
| 57 | AZN | AstraZeneca PLC | Healthcare | 21.00% | $317.61B |
| 58 | IQV | IQVIA Holdings Inc. | Healthcare | 20.91% | $29.62B |
| 59 | COLL | Collegium Pharmaceutical, Inc. | Healthcare | 20.88% | $1.12B |
| 60 | DOCS | Doximity, Inc. | Healthcare | 20.62% | $4.56B |
| 61 | UHS | Universal Health Services, Inc. | Healthcare | 20.46% | $11.13B |
| 62 | HAE | Haemonetics Corporation | Healthcare | 20.43% | $2.86B |
| 63 | PACS | PACS Group, Inc. | Healthcare | 20.23% | $5.53B |
| 64 | GEHC | GE HealthCare Technologies Inc. | Healthcare | 20.08% | $34.07B |
| 65 | BDTX | Black Diamond Therapeutics, Inc. | Healthcare | 19.93% | $0.18B |
| 66 | JYNT | The Joint Corp. | Healthcare | 19.31% | $0.13B |
| 67 | MD | Pediatrix Medical Group, Inc. | Healthcare | 19.10% | $1.92B |
| 68 | MDXG | MiMedx Group, Inc. | Healthcare | 18.94% | $0.51B |
| 69 | UTHR | United Therapeutics Corporation | Healthcare | 18.81% | $25.79B |
| 70 | INSP | Inspire Medical Systems, Inc. | Healthcare | 18.62% | $1.66B |
| 71 | HRMY | Harmony Biosciences Holdings, Inc. | Healthcare | 18.24% | $1.74B |
| 72 | TEVA | Teva Pharmaceutical Industries Limited | Healthcare | 17.83% | $37.73B |
| 73 | SMLR | Semler Scientific, Inc. | Healthcare | 17.72% | $0.31B |
| 74 | ARGX | argenx SE | Healthcare | 17.64% | $52.80B |
| 75 | ELMD | Electromed, Inc. | Healthcare | 17.44% | $0.22B |
| 76 | RDY | Dr. Reddy's Laboratories Limited | Healthcare | 17.00% | $11.07B |
| 77 | PAHC | Phibro Animal Health Corporation | Healthcare | 16.89% | $2.31B |
| 78 | KRYS | Krystal Biotech, Inc. | Healthcare | 16.80% | $8.07B |
| 79 | GMAB | Genmab A/S | Healthcare | 16.47% | $17.53B |
| 80 | PODD | Insulet Corporation | Healthcare | 16.31% | $14.11B |
| 81 | UFPT | UFP Technologies, Inc. | Healthcare | 16.12% | $1.56B |
| 82 | ISRG | Intuitive Surgical, Inc. | Healthcare | 16.02% | $166.65B |
| 83 | OPCH | Option Care Health, Inc. | Healthcare | 15.65% | $4.51B |
| 84 | WST | West Pharmaceutical Services, Inc. | Healthcare | 15.54% | $19.73B |
| 85 | ENSG | The Ensign Group, Inc. | Healthcare | 15.41% | $11.69B |
| 86 | CORT | Corcept Therapeutics Incorporated | Healthcare | 15.38% | $4.91B |
| 87 | PBM | Psyence Biomedical Ltd. | Healthcare | 15.05% | $0.02B |
| 88 | SRTA | Strata Critical Medical, Inc. | Healthcare | 14.82% | $0.40B |
| 89 | ATR | AptarGroup, Inc. | Healthcare | 14.72% | $8.33B |
| 90 | NBIX | Neurocrine Biosciences, Inc. | Healthcare | 14.71% | $13.40B |
| 91 | LMAT | LeMaitre Vascular, Inc. | Healthcare | 14.66% | $2.61B |
| 92 | SPRO | Spero Therapeutics, Inc. | Healthcare | 14.52% | $0.16B |
| 93 | SYK | Stryker Corporation | Healthcare | 14.48% | $131.49B |
| 94 | ANIP | ANI Pharmaceuticals, Inc. | Healthcare | 14.43% | $1.84B |
| 95 | REGN | Regeneron Pharmaceuticals, Inc. | Healthcare | 14.41% | $79.35B |
| 96 | CI | The Cigna Group | Healthcare | 14.28% | $73.47B |
| 97 | DGX | Quest Diagnostics Incorporated | Healthcare | 13.84% | $21.59B |
| 98 | INMD | InMode Ltd. | Healthcare | 13.73% | $0.93B |
| 99 | FBIO | Fortress Biotech, Inc. | Healthcare | 13.66% | $0.08B |
| 100 | MASS | 908 Devices Inc. | Healthcare | 13.56% | $0.27B |
No companies match this search.
How this ranking is built
Companies are ranked by return on equity as reported in their most recent annual filing with the SEC. Figures shown are in US dollars (or percent, as noted), rounded to two decimals.
- Source: annual 10-K / 20-F filings from companies trading on US exchanges (NYSE, Nasdaq, AMEX).
- Fiscal year: whichever annual period the company has most recently filed. Fiscal years don't always align with the calendar year, so the "as of FY" stamp above reflects the most common year across the table.
- Filtered out: warrants, preferred shares, and duplicate listings that share a parent company's financials.
- Update cadence: refreshed as companies file new annual reports (typically within 60–90 days of fiscal year end).
Not financial advice. This is a research tool, not a recommendation.