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Top Healthcare Stocks by Net Margin

Top healthcare companies ranked by net margin, latest annual filings.

What Net Margin Means for Healthcare Companies

Net margin inside healthcare spans one of the widest ranges of any sector because it houses both mature branded pharmaceutical franchises with heavy bottom-line profitability and pre-commercial biotechs running deep losses while their candidate molecules work through clinical trials. Hospitals, medical devices, payers, distributors, and life-science tools each sit in their own sub-economy, with net margins shaped by regulation, payer mix, and the relative weight of research spend inside the income statement.

Why It Matters in Healthcare

For mature pharma and profitable device makers, net margin reflects patent-protected pricing and disciplined research reinvestment, and a consistently strong figure across years usually points to a deep commercial franchise. For biotech, a negative net margin is the expected state rather than a warning. It is worth noting that one-time items such as trial milestones, acquired in-process research charges, and litigation settlements can move healthcare net margin meaningfully in any single reporting period.

What to Read Alongside

Pair net margin with Gross Margin for the top of the margin stack, Operating Margin which captures research intensity, and Return on Equity for how efficiently the capital base translates profit into shareholder return.

Data as of FY 2025 100 companies Rhea AI
# Symbol Company Sector
1 UTHR United Therapeutics Corporation Healthcare 41.94% $22.86B
2 PTCT PTC Therapeutics, Inc. Healthcare 39.46% $5.91B
3 NVAX Novavax, Inc. Healthcare 39.19% $1.27B
4 ACAD ACADIA Pharmaceuticals Inc. Healthcare 36.49% $4.90B
5 EXEL Exelixis, Inc. Healthcare 33.73% $12.93B
6 VRTX Vertex Pharmaceuticals Incorporated Healthcare 32.94% $122.68B
7 RPRX Royalty Pharma plc Healthcare 32.42% $25.38B
8 LLY Eli Lilly & Co. Healthcare 31.67% $1062.44B
9 REGN Regeneron Pharmaceuticals, Inc. Healthcare 31.41% $79.49B
10 ARGX argenx SE Healthcare 30.41% $54.76B
11 BIO Bio-Rad Laboratories, Inc. Healthcare 29.42% $9.16B
12 GILD Gilead Sciences, Inc. Healthcare 28.90% $162.47B
13 JNJ Johnson & Johnson Healthcare 28.46% $619.30B
14 VEEV Veeva Systems Inc. Healthcare 28.44% $35.38B
15 ISRG Intuitive Surgical, Inc. Healthcare 28.38% $132.02B
16 ZTS ZOETIS INC. Healthcare 28.23% $32.39B
17 MRK Merck & Co., Inc. Healthcare 28.08% $317.05B
18 RMD ResMed Inc. Healthcare 27.22% $32.38B
19 GMAB Genmab A/S Healthcare 25.89% $18.31B
20 INCY Incyte Corporation Healthcare 25.03% $24.00B
21 IDXX IDEXX Laboratories, Inc. Healthcare 24.62% $46.48B
22 HALO Halozyme Therapeutics, Inc. Healthcare 22.69% $10.17B
23 MTD Mettler-Toledo International Healthcare 21.59% $28.48B
24 AMGN Amgen Inc. Healthcare 20.98% $219.02B
25 QGEN Qiagen N.V. Healthcare 20.33% $8.61B
26 WAT Waters Corporation Healthcare 20.30% $39.24B
27 ILMN Illumina, Inc. Healthcare 19.57% $29.25B
28 A Agilent Technologies Inc. Healthcare 18.75% $39.92B
29 SOLV Solventum Corporation Healthcare 18.69% $14.12B
30 GMED Globus Medical, Inc. Healthcare 18.30% $11.01B
31 DXCM DexCom, Inc. Healthcare 17.94% $31.33B
32 MEDP Medpace Holdings, Inc. Healthcare 17.83% $16.33B
33 EW Edwards Lifesciences Corporation Healthcare 17.69% $51.48B
34 PBH Prestige Consumer Healthcare Inc. Healthcare 17.48% $2.58B
35 AZN AstraZeneca PLC Healthcare 17.42% $249.80B
36 INDV Indivior Pharmaceuticals, Inc. Healthcare 16.95% $4.56B
37 NBIX Neurocrine Biosciences, Inc. Healthcare 16.73% $16.25B
38 ALKS Alkermes plc Healthcare 16.38% $8.11B
39 HQY HealthEquity, Inc. Healthcare 16.38% $8.65B
40 WST West Pharmaceutical Services, Inc. Healthcare 16.06% $24.53B
41 LNTH Lantheus Holdings, Inc. Healthcare 15.15% $6.60B
42 TMO Thermo Fisher Scientific, Inc. Healthcare 15.08% $214.46B
43 ABT Abbott Laboratories Healthcare 14.72% $186.81B
44 DHR Danaher Corporation Healthcare 14.71% $140.58B
45 BMY Bristol-Myers Squibb Company Healthcare 14.64% $131.04B
46 BSX Boston Scientific Corporation Healthcare 14.41% $71.45B
47 HOLX Hologic, Inc. Healthcare 13.80% $16.97B
48 MDT Medtronic plc Healthcare 13.20% $109.98B
49 STE STERIS plc Healthcare 13.18% $22.59B
50 BIIB Biogen Inc. Healthcare 13.07% $30.48B
51 SYK Stryker Corporation Healthcare 12.92% $129.43B
52 PEN Penumbra, Inc. Healthcare 12.66% $12.80B
53 RDY Dr. Reddy's Laboratories Limited Healthcare 12.63% $10.09B
54 PFE Pfizer Inc. Healthcare 12.42% $149.33B
55 THC Tenet Healthcare Corporation Healthcare 11.11% $20.66B
56 BMRN BioMarin Pharmaceutical Inc. Healthcare 10.83% $11.88B
57 ATR AptarGroup, Inc. Healthcare 10.40% $8.63B
58 WAY Waystar Holding Corp. Healthcare 10.20% $4.48B
59 ALGN Align Technology, Inc. Healthcare 10.16% $12.01B
60 SNN Smith & Nephew plc Healthcare 10.14% $12.47B
61 GEHC GE HealthCare Technologies Inc. Healthcare 10.10% $31.76B
62 EHC Encompass Health Corporation Healthcare 9.54% $12.38B
63 COO The Cooper Companies, Inc. Healthcare 9.16% $14.30B
64 PODD Insulet Corporation Healthcare 9.12% $9.66B
65 DGX Quest Diagnostics Incorporated Healthcare 8.99% $26.32B
66 HCA HCA Healthcare, Inc. Healthcare 8.97% $88.53B
67 EMBC Embecta Corp. Healthcare 8.83% $0.21B
68 MD Pediatrix Medical Group, Inc. Healthcare 8.64% $2.15B
69 UHS Universal Health Services, Inc. Healthcare 8.57% $10.27B
70 ZBH Zimmer Biomet Holdings, Inc. Healthcare 8.57% $18.54B
71 MMSI Merit Medical Systems, Inc. Healthcare 8.48% $5.24B
72 ALNY Alnylam Pharmaceuticals, Inc. Healthcare 8.45% $28.92B
73 RVTY Revvity, Inc. Healthcare 8.45% $12.74B
74 IQV IQVIA Holdings Inc. Healthcare 8.34% $38.26B
75 TEVA Teva Pharmaceutical Industries Limited Healthcare 8.17% $40.56B
76 DVA DaVita Inc. Healthcare 7.91% $11.53B
77 NHC National HealthCare Corporation Healthcare 7.91% $3.43B
78 CON Concentra Group Holdings Parent, Inc. Healthcare 7.69% $3.91B
79 BDX Becton, Dickinson and Co. Healthcare 7.68% $48.79B
80 ABBV AbbVie Inc. Healthcare 6.91% $430.95B
81 ENSG The Ensign Group, Inc. Healthcare 6.80% $10.59B
82 ADUS Addus HomeCare Corporation Healthcare 6.74% $2.22B
83 SHC Sotera Health Company Healthcare 6.70% $5.39B
84 LH Labcorp Holdings Inc. Healthcare 6.29% $25.67B
85 TECH Bio-Techne Corporation Healthcare 6.02% $11.20B
86 ITGR Integer Holdings Corporation Healthcare 5.55% $4.29B
87 HIMS Hims & Hers Health, Inc. Healthcare 5.47% $6.87B
88 ONC BeOne Medicines AG Healthcare 5.37% $36.69B
89 PGNY Progyny, Inc. Healthcare 4.54% $2.37B
90 CYH Community Health Systems, Inc. Healthcare 4.08% $0.42B
91 PAHC Phibro Animal Health Corporation Healthcare 3.72% $1.44B
92 OPCH Option Care Health, Inc. Healthcare 3.67% $3.54B
93 PACS PACS Group, Inc. Healthcare 3.62% $7.39B
94 CNMD CONMED Corporation Healthcare 3.43% $1.49B
95 GRDN Guardian Pharmacy Services, Inc. Healthcare 3.40% $2.50B
96 HCSG Healthcare Services Group, Inc. Healthcare 3.21% $1.51B
97 HSIC Henry Schein, Inc. Healthcare 3.18% $9.83B
98 OGN Organon & Co. Healthcare 3.01% $3.56B
99 ELV Elevance Health, Inc. Healthcare 2.84% $84.88B
100 ICLR ICON Public Limited Company Healthcare 2.78% $12.43B

How this ranking is built

Companies are ranked by net margin as reported in their most recent annual filing with the SEC. Figures shown are in US dollars (or percent, as noted), rounded to two decimals.

  • Source: annual 10-K / 20-F filings from companies trading on US exchanges (NYSE, Nasdaq, AMEX).
  • Fiscal year: whichever annual period the company has most recently filed. Fiscal years don't always align with the calendar year, so the "as of FY" stamp above reflects the most common year across the table.
  • Filtered out: warrants, preferred shares, and duplicate listings that share a parent company's financials.
  • Update cadence: refreshed as companies file new annual reports (typically within 60–90 days of fiscal year end).

Not financial advice. This is a research tool, not a recommendation.