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Top Healthcare Stocks by Net Margin

Top healthcare companies ranked by net margin, latest annual filings.

What Net Margin Means for Healthcare Companies

Net margin inside healthcare spans one of the widest ranges of any sector because it houses both mature branded pharmaceutical franchises with heavy bottom-line profitability and pre-commercial biotechs running deep losses while their candidate molecules work through clinical trials. Hospitals, medical devices, payers, distributors, and life-science tools each sit in their own sub-economy, with net margins shaped by regulation, payer mix, and the relative weight of research spend inside the income statement.

Why It Matters in Healthcare

For mature pharma and profitable device makers, net margin reflects patent-protected pricing and disciplined research reinvestment, and a consistently strong figure across years usually points to a deep commercial franchise. For biotech, a negative net margin is the expected state rather than a warning. It is worth noting that one-time items such as trial milestones, acquired in-process research charges, and litigation settlements can move healthcare net margin meaningfully in any single reporting period.

What to Read Alongside

Pair net margin with Gross Margin for the top of the margin stack, Operating Margin which captures research intensity, and Return on Equity for how efficiently the capital base translates profit into shareholder return.

Data as of FY 2025 100 companies Rhea AI
# Symbol Company Sector
1 UTHR United Therapeutics Corporation Healthcare 41.94% $23.94B
2 PTCT PTC Therapeutics, Inc. Healthcare 39.44% $5.47B
3 NVAX Novavax, Inc. Healthcare 39.19% $1.78B
4 ACAD Acadia Pharmaceuticals Inc. Healthcare 36.49% $3.67B
5 EXEL Exelixis, Inc. Healthcare 33.73% $16.98B
6 NVO Novo Nordisk A/S Healthcare 33.14% $177.74B
7 VRTX Vertex Pharmaceuticals Incorporated Healthcare 32.94% $138.71B
8 RPRX Royalty Pharma plc Healthcare 32.42% $38.60B
9 LLY Eli Lilly and Company Healthcare 31.67% $1.21T
10 REGN Regeneron Pharmaceuticals, Inc. Healthcare 31.41% $93.55B
11 ARGX argenx SE Healthcare 30.41% $58.31B
12 BIO Bio-Rad Laboratories, Inc. Healthcare 29.42% $10.26B
13 GILD Gilead Sciences, Inc. Healthcare 28.90% $207.00B
14 LKFT Lakefront Biotherapeutics NV Healthcare 28.85% $2.20B
15 JNJ Johnson & Johnson Healthcare 28.46% $664.95B
16 VEEV Veeva Systems Inc. Healthcare 28.44% $49.18B
17 ISRG Intuitive Surgical, Inc. Healthcare 28.38% $159.96B
18 ZTS Zoetis Inc. Healthcare 28.23% $32.26B
19 MRK Merck & Co., Inc. Healthcare 28.08% $361.73B
20 RMD ResMed Inc. Healthcare 26.94% $33.10B
21 GMAB Genmab A/S Healthcare 25.89% $32.98B
22 INCY Incyte Corporation Healthcare 25.03% $24.39B
23 NVS Novartis AG Healthcare 24.67% $307.00B
24 IDXX IDEXX Laboratories, Inc. Healthcare 24.62% $53.26B
25 HALO Halozyme Therapeutics, Inc. Healthcare 22.69% $11.81B
26 MTD Mettler-Toledo International Inc. Healthcare 21.59% $34.51B
27 AMGN Amgen Inc. Healthcare 20.98% $249.05B
28 QGEN Qiagen N.V. Healthcare 20.33% $10.39B
29 WAT Waters Corporation Healthcare 20.30% $44.96B
30 ILMN Illumina, Inc. Healthcare 19.57% $32.23B
31 A Agilent Technologies, Inc. Healthcare 18.75% $49.26B
32 SOLV Solventum Corporation Healthcare 18.69% $15.36B
33 GMED Globus Medical, Inc. Healthcare 18.30% $9.43B
34 DXCM DexCom, Inc. Healthcare 17.94% $29.62B
35 MEDP Medpace Holdings, Inc. Healthcare 17.83% $18.27B
36 EW Edwards Lifesciences Corporation Healthcare 17.69% $58.73B
37 GSK GSK plc Healthcare 17.50% $100.88B
38 PBH Prestige Consumer Healthcare Inc. Healthcare 17.48% $2.04B
39 AZN AstraZeneca PLC Healthcare 17.41% $289.14B
40 INDV Indivior Pharmaceuticals, Inc. Healthcare 16.95% $4.28B
41 SUPN Supernus, Inc. Healthcare 16.95% $1.52B
42 NBIX Neurocrine Biosciences, Inc. Healthcare 16.73% $16.66B
43 SNY Sanofi Healthcare 16.72% $112.71B
44 HQY HealthEquity, Inc. Healthcare 16.38% $8.57B
45 ALKS Alkermes plc Healthcare 16.37% $7.71B
46 WST West Pharmaceutical Services, Inc. Healthcare 16.06% $27.85B
47 LNTH Lantheus Holdings, Inc. Healthcare 15.15% $6.58B
48 HLN Haleon plc Healthcare 15.11% $40.17B
49 TMO Thermo Fisher Scientific Inc. Healthcare 15.05% $257.42B
50 TECH Bio-Techne Corporation Healthcare 14.97% $11.43B
51 ABT Abbott Laboratories Healthcare 14.72% $190.43B
52 DHR Danaher Corporation Healthcare 14.71% $161.89B
53 BMY Bristol-Myers Squibb Company Healthcare 14.64% $127.02B
54 BSX Boston Scientific Corporation Healthcare 14.44% $61.96B
55 MDT Medtronic plc Healthcare 13.20% $130.22B
56 STE STERIS plc Healthcare 13.18% $24.50B
57 BIIB Biogen Inc. Healthcare 13.07% $36.71B
58 SYK Stryker Corporation Healthcare 12.92% $124.06B
59 RDY Dr. Reddy's Laboratories Limited Healthcare 12.76% $12.43B
60 PEN Penumbra, Inc. Healthcare 12.66% $12.58B
61 PFE Pfizer Inc. Healthcare 12.42% $167.52B
62 STVN Stevanato Group S.p.A. Healthcare 11.79% $3.71B
63 BMRN BioMarin Pharmaceutical Inc. Healthcare 10.83% $10.85B
64 CHE Chemed Corporation Healthcare 10.48% $6.84B
65 ATR AptarGroup, Inc. Healthcare 10.40% $9.03B
66 WAY Waystar Holding Corp. Healthcare 10.20% $5.45B
67 ALGN Align Technology, Inc. Healthcare 10.17% $11.70B
68 SNN Smith & Nephew plc Healthcare 10.14% $13.04B
69 GEHC GE HealthCare Technologies Inc. Healthcare 10.10% $37.25B
70 EHC Encompass Health Corporation Healthcare 9.54% $13.50B
71 ALC Alcon Inc. Healthcare 9.42% $36.23B
72 AVAH Aveanna Healthcare Holdings Inc. Healthcare 9.25% $2.89B
73 COO The Cooper Companies, Inc. Healthcare 9.16% $11.86B
74 PODD Insulet Corporation Healthcare 9.12% $10.16B
75 DGX Quest Diagnostics Incorporated Healthcare 8.99% $28.21B
76 HCA HCA Healthcare, Inc. Healthcare 8.97% $103.40B
77 EMBC Embecta Corp. Healthcare 8.83% $350.72M
78 MD Pediatrix Medical Group, Inc. Healthcare 8.64% $2.44B
79 UHS Universal Health Services, Inc. Healthcare 8.57% $11.52B
80 ZBH Zimmer Biomet Holdings, Inc. Healthcare 8.57% $19.98B
81 MMSI Merit Medical Systems, Inc. Healthcare 8.48% $5.23B
82 ALNY Alnylam Pharmaceuticals, Inc. Healthcare 8.45% $20.89B
83 RVTY Revvity, Inc. Healthcare 8.45% $17.31B
84 IQV IQVIA Holdings Inc. Healthcare 8.34% $44.80B
85 TEVA Teva Pharmaceutical Industries Limited Healthcare 8.17% $49.72B
86 NHC National HealthCare Corporation Healthcare 7.91% $3.27B
87 CON Concentra Group Holdings Parent, Inc. Healthcare 7.69% $5.34B
88 BDX Becton, Dickinson and Company Healthcare 7.68% $57.71B
89 HAE Haemonetics Corporation Healthcare 7.29% $5.46B
90 ABBV AbbVie Inc. Healthcare 6.91% $514.78B
91 ENSG The Ensign Group, Inc. Healthcare 6.80% $10.56B
92 ADUS Addus HomeCare Corporation Healthcare 6.74% $2.32B
93 SHC Sotera Health Company Healthcare 6.70% $4.57B
94 THC Tenet Healthcare Corporation Healthcare 6.60% $22.55B
95 PAHC Phibro Animal Health Corporation Healthcare 6.57% $1.34B
96 LH Labcorp Holdings Inc. Healthcare 6.28% $29.77B
97 ITGR Integer Holdings Corporation Healthcare 5.55% $4.30B
98 DVA DaVita Inc. Healthcare 5.47% $12.04B
99 HIMS Hims & Hers Health, Inc. Healthcare 5.47% $6.07B
100 ONC BeOne Medicines AG Healthcare 5.37% $46.49B

Net margin is GAAP net income divided by revenue, so one-time gains and tax benefits count in full: a company near the top can show a net margin well above its operating margin for that year.

How this ranking is built

Companies are ranked by net margin as reported in their most recent annual filing with the SEC. Figures shown are in US dollars (or percent, as noted), rounded to two decimals.

  • Source: annual 10-K / 20-F filings from companies trading on US exchanges (NYSE, Nasdaq, AMEX).
  • Fiscal year: whichever annual period the company has most recently filed. Fiscal years don't always align with the calendar year, so the "as of FY" stamp above reflects the most common year across the table.
  • Filtered out: warrants, preferred shares, and duplicate listings that share a parent company's financials.
  • Size floor: A company qualifies at $1 billion in annual revenue or above, so a small filer with a freak ratio cannot top the list.
  • Value range: Only figures above 0% and up to 100% qualify.
  • Market cap: stated at each company's latest close, which is newer than the annual figure ranked here.
  • Update cadence: refreshed as companies file new annual reports (typically within 60–90 days of fiscal year end).

Not financial advice. This is a research tool, not a recommendation.

Frequently asked questions

Why does healthcare net margin vary so much between sub-industries?

Branded pharmaceutical makers and some medical device firms enjoy regulatory and patent-driven pricing power that produces strong bottom-line profitability once a drug or device is commercialized. Hospitals and payers work on volume-driven margin structures that are structurally thinner. Pre-commercial biotechs have no meaningful product revenue yet and their reported net margins can run deeply negative for years as they finance research against future milestone and royalty income. All of these businesses sit inside the same sector label even though their economics differ fundamentally.

Why is it wise to be cautious with single-year healthcare net margins?

Healthcare income statements are frequently disrupted by one-time items: upfront payments on licensing deals, charges for acquired in-process research, pension adjustments, or settlements with government or plaintiff parties. Any of these can move a single year's net margin by a large amount without changing the underlying business economics. Rolling multi-year averages or adjusted figures the company publishes alongside GAAP results often give a more stable read on the structural profitability of the franchise than any single year in isolation.