Top Healthcare Stocks by Net Margin
Top healthcare companies ranked by net margin, latest annual filings.
What Net Margin Means for Healthcare Companies
Net margin inside healthcare spans one of the widest ranges of any sector because it houses both mature branded pharmaceutical franchises with heavy bottom-line profitability and pre-commercial biotechs running deep losses while their candidate molecules work through clinical trials. Hospitals, medical devices, payers, distributors, and life-science tools each sit in their own sub-economy, with net margins shaped by regulation, payer mix, and the relative weight of research spend inside the income statement.
Why It Matters in Healthcare
For mature pharma and profitable device makers, net margin reflects patent-protected pricing and disciplined research reinvestment, and a consistently strong figure across years usually points to a deep commercial franchise. For biotech, a negative net margin is the expected state rather than a warning. It is worth noting that one-time items such as trial milestones, acquired in-process research charges, and litigation settlements can move healthcare net margin meaningfully in any single reporting period.
What to Read Alongside
Pair net margin with [Gross Margin](/financials/top-gross-margin-stocks/healthcare/) for the top of the margin stack, [Operating Margin](/financials/top-operating-margin-stocks/healthcare/) which captures research intensity, and [Return on Equity](/financials/top-roe-stocks/healthcare/) for how efficiently the capital base translates profit into shareholder return.
| # | Symbol | Company | Sector | ||
|---|---|---|---|---|---|
| 1 | TBPH | Theravance Biopharma, Inc. | Healthcare | 98.54% | $0.89B |
| 2 | HCM | HUTCHMED (China) Limited | Healthcare | 83.30% | $2.71B |
| 3 | ZVRA | Zevra Therapeutics, Inc. | Healthcare | 78.17% | $0.63B |
| 4 | NNNN | Anbio Biotechnology | Healthcare | 74.06% | $1.19B |
| 5 | SMLR | Semler Scientific, Inc. | Healthcare | 72.65% | $0.31B |
| 6 | TGTX | TG Therapeutics, Inc. | Healthcare | 72.56% | $5.64B |
| 7 | INVA | Innoviva, Inc. | Healthcare | 65.92% | $1.80B |
| 8 | XOMAO | XOMA Royalty Corporation | Healthcare | 60.81% | – |
| 9 | QTTB | Q32 Bio Inc. | Healthcare | 55.49% | $0.09B |
| 10 | KRYS | Krystal Biotech, Inc. | Healthcare | 52.64% | $8.07B |
| 11 | CRMD | CorMedix Inc. | Healthcare | 52.31% | $0.58B |
| 12 | CGEN | Compugen Ltd. | Healthcare | 48.57% | $0.27B |
| 13 | LGND | Ligand Pharmaceuticals Incorporated | Healthcare | 46.42% | $4.62B |
| 14 | UTHR | United Therapeutics Corporation | Healthcare | 41.94% | $25.79B |
| 15 | PTCT | PTC Therapeutics, Inc. | Healthcare | 39.44% | $6.00B |
| 16 | NVAX | Novavax, Inc. | Healthcare | 39.19% | $1.44B |
| 17 | DOCS | Doximity, Inc. | Healthcare | 39.13% | $4.56B |
| 18 | ACAD | ACADIA Pharmaceuticals Inc. | Healthcare | 36.49% | $3.78B |
| 19 | SMTI | Sanara MedTech Inc. | Healthcare | 36.43% | $0.19B |
| 20 | CPRX | Catalyst Pharmaceuticals, Inc. | Healthcare | 36.39% | $3.21B |
| 21 | KROS | Keros Therapeutics, Inc. | Healthcare | 35.68% | $0.23B |
| 22 | MASS | 908 Devices Inc. | Healthcare | 34.68% | $0.27B |
| 23 | BDMD | Baird Medical Investment Holdings Limited | Healthcare | 34.01% | $0.06B |
| 24 | EXEL | Exelixis, Inc. | Healthcare | 33.73% | $11.40B |
| 25 | VRTX | Vertex Pharmaceuticals Incorporated | Healthcare | 32.94% | $112.22B |
| 26 | RPRX | Royalty Pharma plc | Healthcare | 32.42% | $22.22B |
| 27 | BDTX | Black Diamond Therapeutics, Inc. | Healthcare | 31.95% | $0.18B |
| 28 | LLY | Eli Lilly and Company | Healthcare | 31.67% | $828.17B |
| 29 | TMDX | TransMedics Group, Inc. | Healthcare | 31.43% | $4.00B |
| 30 | REGN | Regeneron Pharmaceuticals, Inc. | Healthcare | 31.41% | $79.35B |
| 31 | ARGX | argenx SE | Healthcare | 30.41% | $52.80B |
| 32 | BCRX | BioCryst Pharmaceuticals, Inc. | Healthcare | 30.16% | $2.38B |
| 33 | BIO | Bio-Rad Laboratories, Inc. | Healthcare | 29.42% | $8.07B |
| 34 | UTMD | Utah Medical Products, Inc. | Healthcare | 29.30% | $0.23B |
| 35 | GILD | Gilead Sciences, Inc. | Healthcare | 28.90% | $170.84B |
| 36 | ADMA | ADMA Biologics, Inc. | Healthcare | 28.80% | $2.56B |
| 37 | JNJ | Johnson & Johnson | Healthcare | 28.46% | $564.05B |
| 38 | VEEV | Veeva Systems Inc. | Healthcare | 28.44% | $27.43B |
| 39 | ISRG | Intuitive Surgical, Inc. | Healthcare | 28.38% | $166.65B |
| 40 | ZTS | Zoetis Inc. | Healthcare | 28.23% | $51.46B |
| 41 | MRK | Merck & Co., Inc. | Healthcare | 28.08% | $294.09B |
| 42 | RMD | ResMed Inc. | Healthcare | 27.22% | $33.23B |
| 43 | ATRA | Atara Biotherapeutics, Inc. | Healthcare | 27.07% | $0.04B |
| 44 | IRMD | IRADIMED CORPORATION | Healthcare | 26.82% | $1.20B |
| 45 | SNWV | SANUWAVE Health, Inc. | Healthcare | 26.82% | $0.18B |
| 46 | GMAB | Genmab A/S | Healthcare | 25.89% | $17.53B |
| 47 | INMD | InMode Ltd. | Healthcare | 25.33% | $0.93B |
| 48 | INCY | Incyte Corporation | Healthcare | 25.03% | $19.47B |
| 49 | IDXX | IDEXX Laboratories, Inc. | Healthcare | 24.62% | $46.80B |
| 50 | SIGA | SIGA Technologies, Inc. | Healthcare | 24.61% | $0.34B |
| 51 | LMAT | LeMaitre Vascular, Inc. | Healthcare | 23.12% | $2.61B |
| 52 | HALO | Halozyme Therapeutics, Inc. | Healthcare | 22.69% | $8.21B |
| 53 | MTD | Mettler-Toledo International Inc. | Healthcare | 21.59% | $27.14B |
| 54 | AMGN | Amgen Inc. | Healthcare | 20.98% | $191.53B |
| 55 | SRTA | Strata Critical Medical, Inc. | Healthcare | 20.97% | $0.40B |
| 56 | QGEN | Qiagen N.V. | Healthcare | 20.33% | $8.50B |
| 57 | WAT | Waters Corporation | Healthcare | 20.30% | $32.18B |
| 58 | ILMN | Illumina, Inc. | Healthcare | 19.57% | $20.43B |
| 59 | PBH | Prestige Consumer Healthcare Inc. | Healthcare | 18.86% | $2.75B |
| 60 | SOLV | Solventum Corporation | Healthcare | 18.69% | $12.22B |
| 61 | GMED | Globus Medical, Inc. | Healthcare | 18.30% | $12.88B |
| 62 | HRMY | Harmony Biosciences Holdings, Inc. | Healthcare | 18.27% | $1.74B |
| 63 | DXCM | DexCom, Inc. | Healthcare | 17.94% | $24.69B |
| 64 | MEDP | Medpace Holdings, Inc. | Healthcare | 17.83% | $14.87B |
| 65 | EW | Edwards Lifesciences Corporation | Healthcare | 17.69% | $46.69B |
| 66 | RDY | Dr. Reddy's Laboratories Limited | Healthcare | 17.61% | $11.07B |
| 67 | AZN | AstraZeneca PLC | Healthcare | 17.42% | $317.61B |
| 68 | INDV | Indivior Pharmaceuticals, Inc. | Healthcare | 16.95% | $3.99B |
| 69 | NBIX | Neurocrine Biosciences, Inc. | Healthcare | 16.73% | $13.40B |
| 70 | HQY | HealthEquity, Inc. | Healthcare | 16.38% | $7.27B |
| 71 | ALKS | Alkermes plc | Healthcare | 16.38% | $5.74B |
| 72 | WST | West Pharmaceutical Services, Inc. | Healthcare | 16.06% | $19.73B |
| 73 | INSP | Inspire Medical Systems, Inc. | Healthcare | 15.95% | $1.66B |
| 74 | LNTH | Lantheus Holdings, Inc. | Healthcare | 15.15% | $5.46B |
| 75 | TMO | Thermo Fisher Scientific Inc. | Healthcare | 15.08% | $195.70B |
| 76 | ABT | Abbott Laboratories | Healthcare | 14.72% | $168.22B |
| 77 | DHR | Danaher Corporation | Healthcare | 14.71% | $137.82B |
| 78 | BMY | Bristol-Myers Squibb Company | Healthcare | 14.64% | $122.85B |
| 79 | BSX | Boston Scientific Corporation | Healthcare | 14.41% | $95.46B |
| 80 | BTMD | biote Corp. | Healthcare | 14.07% | $0.07B |
| 81 | MDT | Medtronic plc | Healthcare | 13.90% | $110.66B |
| 82 | HOLX | Hologic, Inc. | Healthcare | 13.80% | $16.97B |
| 83 | AMPH | Amphastar Pharmaceuticals, Inc. | Healthcare | 13.63% | $1.02B |
| 84 | PBYI | Puma Biotechnology, Inc. | Healthcare | 13.62% | $0.38B |
| 85 | PDEX | Pro-Dex, Inc. | Healthcare | 13.48% | $0.17B |
| 86 | NAGE | Niagen Bioscience, Inc. | Healthcare | 13.43% | $0.39B |
| 87 | CORT | Corcept Therapeutics Incorporated | Healthcare | 13.09% | $4.91B |
| 88 | BIIB | Biogen Inc. | Healthcare | 13.07% | $26.03B |
| 89 | SYK | Stryker Corporation | Healthcare | 12.92% | $131.49B |
| 90 | SPRO | Spero Therapeutics, Inc. | Healthcare | 12.83% | $0.16B |
| 91 | VCYT | Veracyte, Inc. | Healthcare | 12.83% | $2.69B |
| 92 | PEN | Penumbra, Inc. | Healthcare | 12.66% | $13.03B |
| 93 | PFE | Pfizer Inc. | Healthcare | 12.42% | $156.77B |
| 94 | HAE | Haemonetics Corporation | Healthcare | 12.32% | $2.86B |
| 95 | ELMD | Electromed, Inc. | Healthcare | 11.78% | $0.22B |
| 96 | MDXG | MiMedx Group, Inc. | Healthcare | 11.60% | $0.51B |
| 97 | SPOK | Spok Holdings, Inc. | Healthcare | 11.37% | $0.24B |
| 98 | UFPT | UFP Technologies, Inc. | Healthcare | 11.33% | $1.56B |
| 99 | STE | STERIS plc | Healthcare | 11.26% | $22.14B |
| 100 | MHUA | Meihua International Medical Technologies Co., Ltd. | Healthcare | 11.19% | $0.43B |
No companies match this search.
How this ranking is built
Companies are ranked by net margin as reported in their most recent annual filing with the SEC. Figures shown are in US dollars (or percent, as noted), rounded to two decimals.
- Source: annual 10-K / 20-F filings from companies trading on US exchanges (NYSE, Nasdaq, AMEX).
- Fiscal year: whichever annual period the company has most recently filed. Fiscal years don't always align with the calendar year, so the "as of FY" stamp above reflects the most common year across the table.
- Filtered out: warrants, preferred shares, and duplicate listings that share a parent company's financials.
- Update cadence: refreshed as companies file new annual reports (typically within 60–90 days of fiscal year end).
Not financial advice. This is a research tool, not a recommendation.