Stock Market News for October 21, 2026

At a glance

On October 21, 2026, Philip Morris reported Q3 adjusted EPS of $2.36 and $11.4 billion revenue; Roivant said brepocitinib met primary and all key secondary endpoints in two Phase 3 NIU trials, extending median time to treatment failure beyond 48 weeks versus ~12 weeks with placebo; Abbott announced a planned separation of its Nutrition business with approximately $8.5 billion in annual sales; Thermo Fisher reported Q3 revenue of $12.14 billion.

Drug trials and approvals

Roivant Sciences (ROIV) reported positive results in two Phase 3 non-infectious uveitis trials where once-daily 45 mg brepocitinib extended median time to treatment failure beyond 48 weeks versus ~12 weeks with placebo and achieved steroid-free disease inactivity at Week 48 in 62% vs 20% (pooled, p<0.0001).

BioCryst Pharmaceuticals (BCRX) announced FDA approval of ORLADEYO 150 mg oral pellets to prevent hereditary angioedema attacks in patients aged 12 and older.

Earnings and guidance

Philip Morris International (PM) reported third-quarter results with adjusted diluted EPS of $2.36, reported diluted EPS of $2.12, and revenue of $11.4 billion, with adjusted EPS up 5.4% year over year.

Thermo Fisher Scientific (TMO) reported third-quarter results with revenue of $12.14 billion, GAAP diluted EPS of $4.64 and adjusted EPS of $6.68, and GAAP operating income of $2.26 billion.

Abbott Laboratories (ABT) announced intention to separate its global Nutrition business into an independent, publicly traded company by the end of 2027, a business the company says has approximately $8.5 billion in annual sales and will be distributed to Abbott shareholders in a transaction intended to be tax-free for U.S. federal income tax purposes.

Abbott Laboratories (ABT) reported third-quarter results with sales of $13,013 million, GAAP diluted EPS of $0.53 and adjusted diluted EPS of $1.42, and tightened its full-year adjusted EPS range to $5.50–$5.55.

Danaher (DHR) reported third-quarter results with revenue of $6.554 billion, net earnings from continuing operations of $1.207 billion and non-GAAP adjusted diluted EPS of $2.11, and raised full-year adjusted earnings guidance.

AT&T (T) reported third-quarter results with revenue of $32.3 billion, adjusted EPS of $0.65, diluted EPS from continuing operations of $0.13, and a $2.6 billion non-cash impairment tied to the agreed Mexico wireless sale.

Elevance Health (ELV) reported third-quarter results and raised guidance after Q3 operating revenue of $50.4 billion and diluted EPS of $6.27; the company raised full-year adjusted EPS guidance to at least $29.00 per share and raised operating cash flow guidance to at least $6.5 billion.

Teledyne Technologies (TDY) reported third-quarter results with record sales of $1,684.9 million, GAAP diluted EPS of $5.82 and raised its full-year GAAP diluted EPS outlook to $21.71–$21.87.

Wabtec (WAB) reported third-quarter results and raised guidance with sales of $3.12 billion, GAAP diluted EPS of $2.42, adjusted EPS of $2.83, and raised and tightened its 2026 adjusted EPS guidance.

CME Group (CME) reported record third-quarter revenue of $1,737.3 million, with net income of $1,036.9 million and diluted EPS of $2.89, and a third-quarter record average daily volume of 29.4 million contracts.

Stifel Financial (SF) reported third-quarter results with net income available to common shareholders of $224.8 million, diluted EPS of $1.40 and adjusted diluted EPS of $1.46.

AI, infrastructure and partnerships

Dell Technologies (DELL) expanded its NVIDIA-based AI portfolio with enterprise software, deskside systems and data center infrastructure, saying the Dell AI Factory with NVIDIA now has more than 6,500 customers (up from 5,000 last quarter) and adding validated Reflection and Mistral solutions and deployment templates for deskside AI.

CrowdStrike Holdings (CRWD) expanded collaboration with NVIDIA to extend AI agent security from software runtimes to hardware by integrating Falcon Guardian with NVIDIA OpenShell and planning an integration with NVIDIA Sentry on BlueField-4 DPU technology.

ServiceNow (NOW) made Arc generally available as a personal enterprise AI agent included at no additional cost with certain SKUs, enforced through its Super Intelligence Control Tower and NVIDIA OpenShell, with Mac support live and Windows support expected within weeks.

Amkor Technology (AMKR) announced a $1.3 billion agreement with NVIDIA to support expansion of semiconductor packaging capacity in South Korea, bringing their multi-year agreements in Arizona and South Korea to $3 billion in total commitments.

Vertiv Holdings (VRT) introduced an AI factory approach with NVIDIA modeling a target of up to 30% more cumulative AI token output in the first 12 months using pre-engineered reference designs and virtual validation (the target is modeled, not an achieved result).

Financings and buybacks

INVE Technologies (INVE) commenced a modified Dutch auction tender offer to repurchase up to $20 million of its common stock at prices from $2.85 to $3.40 per share, expiring November 19, 2026.

Other notable news

United Airlines Holdings (UAL) opened a new concourse at Houston George Bush Intercontinental Airport—Terminal B North Concourse—with 22 mainline gates and a 54,000-square-foot United Club seating 800 travelers, opening to the public October 22, 2026.